{
"description": "Mean HbA1c at 12 months in Ding 2015 was 7.17 % in Surgery group (n = 18) and 7.15% in Medical/Lifestyle group (n = 22), mean difference 0.02% (95% CI -0.16% to 0.20%)",
"_filename": "example/Evidence-47748.json",
"package_name": "hl7.fhir.uv.ebm",
"statistic": [ {
"note": [ {
"text": "Mean HbA1c at 12 months in Ding 2015 was 7.17 % in Surgery group (n = 18) and 7.15% in Medical/Lifestyle group (n = 22)"
} ],
"quantity": {
"code": "%",
"unit": "%",
"value": 0.2,
"system": "http://unitsofmeasure.org"
},
"sampleSize": {
"knownDataCount": 40,
"numberOfParticipants": 40
},
"description": "mean difference 0.02% (95% CI -0.16% to 0.20%)",
"statisticType": {
"coding": [ {
"code": "0000457",
"system": "http://terminology.hl7.org/CodeSystem/statistic-type",
"display": "Mean Difference"
} ]
},
"attributeEstimate": [ {
"type": {
"coding": [ {
"code": "C53324",
"system": "http://terminology.hl7.org/CodeSystem/attribute-estimate-type",
"display": "Confidence interval"
} ]
},
"level": 0.95,
"range": {
"low": {
"code": "%",
"unit": "%",
"value": -0.16,
"system": "http://unitsofmeasure.org"
},
"high": {
"code": "%",
"unit": "%",
"value": 0.2,
"system": "http://unitsofmeasure.org"
}
},
"description": "95% CI -0.16% to 0.20%"
} ]
} ],
"date": "2022-05-29T11:04:02.111Z",
"meta": {
"profile": [ "http://hl7.org/fhir/uv/ebm/StructureDefinition/comparative-evidence", "http://hl7.org/fhir/uv/ebm/StructureDefinition/single-study-evidence" ],
"versionId": "18",
"lastUpdated": "2023-12-06T18:56:16.372Z"
},
"publisher": "Computable Publishing LLC",
"name": "ComparativeEvidence_Mean_difference_in_HbA1c_between_Surgery_and_Medical_Lifestyle_groups_in_Ding_2015",
"useContext": [ {
"code": {
"code": "evidence-communication",
"system": "https://fevir.net/resources/CodeSystem/179423",
"display": "Evidence Communication"
},
"valueCodeableConcept": {
"coding": [ {
"code": "ComparativeEvidence",
"system": "https://fevir.net/resources/CodeSystem/179423",
"display": "ComparativeEvidence"
} ]
}
}, {
"code": {
"code": "evidence-communication",
"system": "https://fevir.net/resources/CodeSystem/179423",
"display": "Evidence Communication"
},
"valueCodeableConcept": {
"coding": [ {
"code": "SingleStudyEvidence",
"system": "https://fevir.net/resources/CodeSystem/179423",
"display": "SingleStudyEvidence"
} ]
}
} ],
"copyright": "https://creativecommons.org/licenses/by-nc-sa/4.0/",
"type": null,
"experimental": null,
"resourceType": "Evidence",
"variableDefinition": [ {
"observed": {
"type": "Group",
"display": "Ding 2015 Trial Enrollment Group"
},
"description": "40 patients aged 21 to 65 with T2DM and BMI 30 to 45 and HbA1c >= 6.5",
"variableRole": "population"
}, {
"intended": {
"type": "EvidenceVariable",
"display": "GroupAssignment: Bariatric Surgery vs. no bariatric surgery",
"reference": "EvidenceVariable/172427"
},
"description": "Laparoscopic Adjustable Gastric Banding vs. medical treatment (Intensive Medical Diabetes and Weight Management IMWM)",
"variableRole": "exposure",
"comparatorCategory": "no bariatric surgery"
}, {
"observed": {
"type": "EvidenceVariable",
"display": "OutcomeVariable: HbA1c at 12 months",
"reference": "EvidenceVariable/173243"
},
"description": "HbA1c at 12 months",
"variableRole": "outcome"
} ],
"title": "ComparativeEvidence: Mean difference in HbA1c between Surgery and Medical/Lifestyle groups in Ding 2015",
"package_version": "1.0.0-ballot2",
"author": [ {
"name": "Brian S. Alper"
} ],
"synthesisType": {
"coding": [ {
"code": "NotApplicable",
"system": "http://terminology.hl7.org/CodeSystem/synthesis-type",
"display": "not applicable"
} ]
},
"extension": [ {
"url": "http://hl7.org/fhir/uv/ebm/StructureDefinition/relates-to",
"extension": [ {
"url": "type",
"valueCode": "derived-from"
}, {
"url": "targetUri",
"valueUri": "https://diabetesjournals.org/care/article/39/6/861/29305/Metabolic-Surgery-in-the-Treatment-Algorithm-for"
}, {
"url": "targetMarkdown",
"valueMarkdown": "Metabolic Surgery in the Treatment Algorithm for Type 2 Diabetes: A Joint Statement by International Diabetes Organizations [Journal Article]. Contributors: Francesco Rubino, David M Nathan, Robert H Eckel, Philip R Schauer, K George M M Alberti, Paul Z Zimmet, Stefano Del Prato, Linong Ji, Shaukat M Sadikot, William H Herman, Stephanie A Amiel, Lee M Kaplan, Gaspar Taroncher-Oldenburg, David E Cummings, Delegates of the 2nd Diabetes Surgery Summit. In: Diabetes care, PMID 27222544. Published June 2016. Available at: https://pubmed.ncbi.nlm.nih.gov/27222544/."
} ]
}, {
"url": "http://hl7.org/fhir/uv/ebm/StructureDefinition/relates-to",
"extension": [ {
"url": "type",
"valueCode": "cite-as"
}, {
"url": "targetMarkdown",
"valueMarkdown": "ComparativeEvidence: Mean difference in HbA1c between Surgery and Medical/Lifestyle groups in Ding 2015 [Evidence]. Contributors: In: Fast Evidence Interoperability Resources (FEvIR) Platform, FOI 47748. Revised 2022-05-29. Available at: https://fevir.net/resources/Evidence/47748. Computable resource at: https://fevir.net/resources/Evidence/47748."
} ]
} ],
"status": "active",
"id": "99789959-3048-4711-a6e5-e5a051bf551e",
"kind": null,
"url": "https://fevir.net/resources/Evidence/47748",
"identifier": [ {
"type": {
"text": "FEvIR Object Identifier",
"coding": [ {
"code": "ACSN",
"system": "http://terminology.hl7.org/CodeSystem/v2-0203",
"display": "Accession ID"
} ]
},
"value": "47748",
"system": "https://fevir.net",
"assigner": {
"display": "Computable Publishing LLC"
}
} ],
"version": null,
"studyDesign": [ {
"coding": [ {
"code": "SEVCO:01003",
"system": "https://fevir.net/sevco",
"display": "randomized assignment"
} ]
} ],
"contact": [ {
"telecom": [ {
"value": "support@computablepublishing.com",
"system": "email"
} ]
} ]
}