PackagesCanonicalsLogsProblems
    Packages
    de.medizininformatikinitiative.kerndatensatz.mtb@2025.0.0-ballot-alpha.1
    https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/LogicalModel/mii-lm-mtb
{
  "description": "MII Logical Model Modul Molekulares Tumorboard",
  "_filename": "StructureDefinition-mii-lm-mtb.json",
  "package_name": "de.medizininformatikinitiative.kerndatensatz.mtb",
  "date": null,
  "derivation": "specialization",
  "publisher": "Medizininformatik Initiative",
  "fhirVersion": "4.0.1",
  "name": "MII_LM_MTB",
  "mapping": [ {
    "name": "MII MAP Molekulares Tumorboard",
    "comment": "MII Mappings Modul Molekulares Tumorboard",
    "identity": "mii-map-mtb"
  } ],
  "abstract": false,
  "type": "https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/LogicalModel/mii-lm-mtb",
  "experimental": null,
  "resourceType": "StructureDefinition",
  "title": "MII LM Molekulares Tumorboard",
  "package_version": "2025.0.0-ballot-alpha.1",
  "status": "draft",
  "id": "8b16e687-be9f-448e-aa39-1c750f29bf58",
  "kind": "logical",
  "url": "https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/LogicalModel/mii-lm-mtb",
  "version": "2024.0.0-ballot",
  "differential": {
    "element": [ {
      "id": "mii-lm-mtb",
      "path": "mii-lm-mtb",
      "short": "MII LM Molekulares Tumorboard",
      "definition": "MII Logical Model Modul Molekulares Tumorboard"
    }, {
      "id": "mii-lm-mtb.Behandlungsepisode",
      "max": "1",
      "min": 1,
      "path": "mii-lm-mtb.Behandlungsepisode",
      "type": [ {
        "code": "BackboneElement"
      } ],
      "short": "Behandlungsepisode",
      "mapping": [ {
        "map": "ClinicalImpression",
        "identity": "mii-map-mtb"
      } ],
      "definition": "Behandlungsepisode"
    }, {
      "id": "mii-lm-mtb.Behandlungsepisode.Anmeldedatum",
      "max": "1",
      "min": 1,
      "path": "mii-lm-mtb.Behandlungsepisode.Anmeldedatum",
      "type": [ {
        "code": "date"
      } ],
      "short": "Anmeldedatum",
      "mapping": [ {
        "map": "ClinicalImpression.effectiveDateTime",
        "identity": "mii-map-mtb"
      } ],
      "definition": "Anmeldedatum für das Molekulare Tumorboard"
    }, {
      "id": "mii-lm-mtb.Behandlungsepisode.KrankengeschichteFamilie",
      "max": "1",
      "min": 0,
      "path": "mii-lm-mtb.Behandlungsepisode.KrankengeschichteFamilie",
      "type": [ {
        "code": "Reference",
        "targetProfile": [ "http://hl7.org/fhir/StructureDefinition/FamilyMemberHistory" ]
      } ],
      "short": "Verweis auf Krankengeschichte Familie",
      "mapping": [ {
        "map": "ClinicalImpression.investigation.item:Reference(FamilyMemberHistory)",
        "identity": "mii-map-mtb"
      } ],
      "definition": "Verweis auf die familiäre Krankengeschichte"
    }, {
      "id": "mii-lm-mtb.Behandlungsepisode.NGSBericht",
      "max": "*",
      "min": 0,
      "path": "mii-lm-mtb.Behandlungsepisode.NGSBericht",
      "type": [ {
        "code": "Reference",
        "targetProfile": [ "http://hl7.org/fhir/StructureDefinition/DiagnosticReport" ]
      } ],
      "short": "Verweis auf NGS Bericht",
      "mapping": [ {
        "map": "ClinicalImpression.investigation.item:Reference(DiagnosticReport)",
        "identity": "mii-map-mtb"
      } ],
      "definition": "Verweis auf Next Generation Sequencing Bericht"
    }, {
      "id": "mii-lm-mtb.Behandlungsepisode.MolekularPathologieBefund",
      "max": "*",
      "min": 0,
      "path": "mii-lm-mtb.Behandlungsepisode.MolekularPathologieBefund",
      "type": [ {
        "code": "Reference",
        "targetProfile": [ "http://hl7.org/fhir/StructureDefinition/DiagnosticReport" ]
      } ],
      "short": "Verweis auf Molekular Pathologie Befund",
      "mapping": [ {
        "map": "ClinicalImpression.investigation.item:Reference(DiagnosticReport)",
        "identity": "mii-map-mtb"
      } ],
      "definition": "Verweis auf Molekular Pathologie Befund"
    }, {
      "id": "mii-lm-mtb.Behandlungsepisode.Einwilligung",
      "max": "1",
      "min": 1,
      "path": "mii-lm-mtb.Behandlungsepisode.Einwilligung",
      "type": [ {
        "code": "BackboneElement"
      } ],
      "short": "Einwilligung",
      "mapping": [ {
        "map": "Consent",
        "identity": "mii-map-mtb"
      } ],
      "definition": "Einwilligung zum Molekularen Tumorboard"
    }, {
      "id": "mii-lm-mtb.Behandlungsepisode.Einwilligung.Status",
      "max": "1",
      "min": 1,
      "path": "mii-lm-mtb.Behandlungsepisode.Einwilligung.Status",
      "type": [ {
        "code": "code"
      } ],
      "short": "Status Einwilligung",
      "mapping": [ {
        "map": "Consent.status",
        "identity": "mii-map-mtb"
      } ],
      "definition": "Status der Einwilligung zum Molekularen Tumorboard"
    }, {
      "id": "mii-lm-mtb.Behandlungsepisode.Diagnose",
      "max": "1",
      "min": 1,
      "path": "mii-lm-mtb.Behandlungsepisode.Diagnose",
      "type": [ {
        "code": "BackboneElement"
      } ],
      "short": "Diagnose",
      "mapping": [ {
        "map": "Condition",
        "identity": "mii-map-mtb"
      } ],
      "definition": "Diagnose"
    }, {
      "id": "mii-lm-mtb.Behandlungsepisode.Diagnose.Diagnose",
      "max": "1",
      "min": 0,
      "path": "mii-lm-mtb.Behandlungsepisode.Diagnose.Diagnose",
      "type": [ {
        "code": "Reference"
      } ],
      "short": "Verweis auf Diagnose",
      "mapping": [ {
        "map": "Condition.where(meta.profile = 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-diagnose-primaertumor')",
        "identity": "mii-map-mtb"
      } ],
      "definition": "Verweis auf Diagnose"
    }, {
      "id": "mii-lm-mtb.Behandlungsepisode.Diagnose.Histologie",
      "max": "1",
      "min": 0,
      "path": "mii-lm-mtb.Behandlungsepisode.Diagnose.Histologie",
      "type": [ {
        "code": "Reference"
      } ],
      "short": "Verweis auf Histologiebefund",
      "mapping": [ {
        "map": "Observation.where(meta.profile = 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-histologie-icdo3')",
        "identity": "mii-map-mtb"
      } ],
      "definition": "Verweis auf den Befund zur Histologie des Tumors"
    }, {
      "id": "mii-lm-mtb.Behandlungsepisode.Diagnose.WHOGradZNS",
      "max": "1",
      "min": 0,
      "path": "mii-lm-mtb.Behandlungsepisode.Diagnose.WHOGradZNS",
      "type": [ {
        "code": "code"
      } ],
      "short": "WHO-Grad ZNS Tumor",
      "mapping": [ {
        "map": "Condition.stage.assessment:Reference(Observation)",
        "identity": "mii-map-mtb"
      } ],
      "definition": "Grad des Tumors nach WHO Klassifikation der Tumoren des zentralen Nervensystems (ZNS)"
    }, {
      "id": "mii-lm-mtb.Behandlungsepisode.Diagnose.TumorausbreitungED",
      "max": "1",
      "min": 1,
      "path": "mii-lm-mtb.Behandlungsepisode.Diagnose.TumorausbreitungED",
      "type": [ {
        "code": "BackboneElement"
      } ],
      "short": "Tumorausbreitung ED",
      "mapping": [ {
        "map": "Condition.stage.assessment:Reference(Observation)",
        "identity": "mii-map-mtb"
      } ],
      "definition": "Tumorausbreitung zum Zeitpunkt der Erstdiagnose"
    }, {
      "id": "mii-lm-mtb.Behandlungsepisode.Diagnose.TumorausbreitungED.Wert",
      "max": "1",
      "min": 1,
      "path": "mii-lm-mtb.Behandlungsepisode.Diagnose.TumorausbreitungED.Wert",
      "type": [ {
        "code": "code"
      } ],
      "short": "Wert",
      "mapping": [ {
        "map": "Observation.valueCodeableConcept.coding.code",
        "identity": "mii-map-mtb"
      } ],
      "definition": "Wert Tumorausbreitung"
    }, {
      "id": "mii-lm-mtb.Behandlungsepisode.Diagnose.TumorausbreitungED.Zeitpunkt",
      "max": "1",
      "min": 1,
      "path": "mii-lm-mtb.Behandlungsepisode.Diagnose.TumorausbreitungED.Zeitpunkt",
      "type": [ {
        "code": "dateTime"
      } ],
      "short": "Zeitpunkt",
      "mapping": [ {
        "map": "Observation.effectiveDateTime",
        "identity": "mii-map-mtb"
      } ],
      "definition": "Zeitpunkt der Tumorausbreitung"
    }, {
      "id": "mii-lm-mtb.Behandlungsepisode.Diagnose.TumorausbreitungMTB",
      "max": "1",
      "min": 1,
      "path": "mii-lm-mtb.Behandlungsepisode.Diagnose.TumorausbreitungMTB",
      "type": [ {
        "code": "BackboneElement"
      } ],
      "short": "Tumorausbreitung MTB",
      "mapping": [ {
        "map": "Condition.stage.assessment:Reference(Observation)",
        "identity": "mii-map-mtb"
      } ],
      "definition": "Tumorausbreitung zum Zeitpunkt der MTB-Anmeldung"
    }, {
      "id": "mii-lm-mtb.Behandlungsepisode.Diagnose.TumorausbreitungMTB.Wert",
      "max": "1",
      "min": 1,
      "path": "mii-lm-mtb.Behandlungsepisode.Diagnose.TumorausbreitungMTB.Wert",
      "type": [ {
        "code": "code"
      } ],
      "short": "Wert",
      "mapping": [ {
        "map": "Observation.valueCodeableConcept.coding.code",
        "identity": "mii-map-mtb"
      } ],
      "definition": "Wert Tumorausbreitung"
    }, {
      "id": "mii-lm-mtb.Behandlungsepisode.Diagnose.TumorausbreitungMTB.Zeitpunkt",
      "max": "1",
      "min": 1,
      "path": "mii-lm-mtb.Behandlungsepisode.Diagnose.TumorausbreitungMTB.Zeitpunkt",
      "type": [ {
        "code": "dateTime"
      } ],
      "short": "Zeitpunkt",
      "mapping": [ {
        "map": "Observation.effectiveDateTime",
        "identity": "mii-map-mtb"
      } ],
      "definition": "Zeitpunkt der Tumorausbreitung"
    }, {
      "id": "mii-lm-mtb.Behandlungsepisode.Diagnose.LeitlinienbehandlungStatus",
      "max": "1",
      "min": 0,
      "path": "mii-lm-mtb.Behandlungsepisode.Diagnose.LeitlinienbehandlungStatus",
      "type": [ {
        "code": "code"
      } ],
      "short": "Status Leitlinienbehandlung",
      "mapping": [ {
        "map": "Condition.extension(LeitlinenbehandlungStatus)",
        "identity": "mii-map-mtb"
      } ],
      "definition": "Status der Leitlinienbehandlung"
    }, {
      "id": "mii-lm-mtb.Behandlungsepisode.Vortherapie",
      "max": "*",
      "min": 1,
      "path": "mii-lm-mtb.Behandlungsepisode.Vortherapie",
      "type": [ {
        "code": "BackboneElement"
      } ],
      "short": "Vortherapie",
      "mapping": [ {
        "map": "Procedure",
        "identity": "mii-map-mtb"
      } ],
      "definition": "Vortherapie"
    }, {
      "id": "mii-lm-mtb.Behandlungsepisode.Vortherapie.Diagnose",
      "max": "*",
      "min": 0,
      "path": "mii-lm-mtb.Behandlungsepisode.Vortherapie.Diagnose",
      "type": [ {
        "code": "Reference",
        "targetProfile": [ "http://hl7.org/fhir/StructureDefinition/Condition" ]
      } ],
      "short": "Verweis auf Diagnose",
      "mapping": [ {
        "map": "Procedure.reasonReference:Reference(Condition)",
        "identity": "mii-map-mtb"
      } ],
      "definition": "Verweis auf i.d.R. die Anmeldediagnose, in seltenen Fällen weitere Diagnosen"
    }, {
      "id": "mii-lm-mtb.Behandlungsepisode.Vortherapie.Zulassungsstatus",
      "max": "1",
      "min": 0,
      "path": "mii-lm-mtb.Behandlungsepisode.Vortherapie.Zulassungsstatus",
      "type": [ {
        "code": "code"
      } ],
      "short": "Zulassungsstatus",
      "mapping": [ {
        "map": "ClinicalImpression.extension.extension(Zulassungsstatus)",
        "identity": "mii-map-mtb"
      } ],
      "definition": "Zulassungsstatus der Vortherapie"
    }, {
      "id": "mii-lm-mtb.Behandlungsepisode.Vortherapie.Therapielinie",
      "max": "1",
      "min": 0,
      "path": "mii-lm-mtb.Behandlungsepisode.Vortherapie.Therapielinie",
      "type": [ {
        "code": "unsignedInt"
      } ],
      "short": "Therapielinie",
      "mapping": [ {
        "map": "ClinicalImpression.extension.extension(Therapielinie)",
        "identity": "mii-map-mtb"
      } ],
      "definition": "Therapielinie der Vortherapie (0 bis 9)"
    }, {
      "id": "mii-lm-mtb.Behandlungsepisode.Vortherapie.Startdatum",
      "max": "1",
      "min": 0,
      "path": "mii-lm-mtb.Behandlungsepisode.Vortherapie.Startdatum",
      "type": [ {
        "code": "dateTime"
      } ],
      "short": "Startdatum",
      "mapping": [ {
        "map": "Procedure.performedPeriod.start",
        "identity": "mii-map-mtb"
      } ],
      "definition": "Startdatum der Vortherapie"
    }, {
      "id": "mii-lm-mtb.Behandlungsepisode.Vortherapie.Enddatum",
      "max": "1",
      "min": 0,
      "path": "mii-lm-mtb.Behandlungsepisode.Vortherapie.Enddatum",
      "type": [ {
        "code": "dateTime"
      } ],
      "short": "Enddatum",
      "mapping": [ {
        "map": "Procedure.performedPeriod.end",
        "identity": "mii-map-mtb"
      } ],
      "definition": "Enddatum der Vortherapie"
    }, {
      "id": "mii-lm-mtb.Behandlungsepisode.Vortherapie.Wirkstoffe",
      "max": "*",
      "min": 0,
      "path": "mii-lm-mtb.Behandlungsepisode.Vortherapie.Wirkstoffe",
      "type": [ {
        "code": "code"
      } ],
      "short": "Wirkstoffe",
      "mapping": [ {
        "map": "MedicationStatement.medicationCodeableConcept",
        "identity": "mii-map-mtb"
      } ],
      "definition": "Wirkstoffe der systemischen Leitlinientherapie"
    }, {
      "id": "mii-lm-mtb.Behandlungsepisode.Vortherapie.Abbruchsgrund",
      "max": "1",
      "min": 0,
      "path": "mii-lm-mtb.Behandlungsepisode.Vortherapie.Abbruchsgrund",
      "type": [ {
        "code": "code"
      } ],
      "short": "Abbruchsgrund",
      "mapping": [ {
        "map": "Procedure.outcome.coding.code",
        "identity": "mii-map-mtb"
      } ],
      "definition": "Gibt den Grund an, warum die Systemtherapie beendet wurde"
    }, {
      "id": "mii-lm-mtb.Behandlungsepisode.Vortherapie.Kategorie",
      "max": "1",
      "min": 0,
      "path": "mii-lm-mtb.Behandlungsepisode.Vortherapie.Kategorie",
      "type": [ {
        "code": "code"
      } ],
      "short": "Kategorie",
      "mapping": [ {
        "map": "Procedure.category",
        "identity": "mii-map-mtb"
      } ],
      "definition": "Kategorie der Leitlinientherapie (Prozedur)"
    }, {
      "id": "mii-lm-mtb.Behandlungsepisode.ECOG",
      "max": "*",
      "min": 0,
      "path": "mii-lm-mtb.Behandlungsepisode.ECOG",
      "type": [ {
        "code": "BackboneElement"
      } ],
      "short": "ECOG Performance Status",
      "mapping": [ {
        "map": "Observation",
        "identity": "mii-map-mtb"
      } ],
      "definition": "ECOG Performance Status bei Einschluss ins Molekulare Tumorboard"
    }, {
      "id": "mii-lm-mtb.Behandlungsepisode.ECOG.Datum",
      "max": "1",
      "min": 0,
      "path": "mii-lm-mtb.Behandlungsepisode.ECOG.Datum",
      "type": [ {
        "code": "dateTime"
      } ],
      "short": "Bestimmungsdatum",
      "mapping": [ {
        "map": "Observation.effectiveDateTime",
        "identity": "mii-map-mtb"
      } ],
      "definition": "Bestimmungsdatum des ECOG Performance Status"
    }, {
      "id": "mii-lm-mtb.Behandlungsepisode.ECOG.AllgemeinerLeistungszustand",
      "max": "1",
      "min": 0,
      "path": "mii-lm-mtb.Behandlungsepisode.ECOG.AllgemeinerLeistungszustand",
      "type": [ {
        "code": "code"
      } ],
      "short": "Verweis auf Allgemeiner Leistungszustand",
      "mapping": [ {
        "map": "Observation.valueCodeableConcept",
        "identity": "mii-map-mtb"
      } ],
      "definition": "Verweis auf die Bewertung des allgemeinen Leistungszustandes"
    }, {
      "id": "mii-lm-mtb.Behandlungsepisode.Probe",
      "max": "*",
      "min": 0,
      "path": "mii-lm-mtb.Behandlungsepisode.Probe",
      "type": [ {
        "code": "BackboneElement"
      } ],
      "short": "Histologie und Tumorzellgehalt",
      "mapping": [ {
        "map": "Specimen",
        "identity": "mii-map-mtb"
      } ],
      "definition": "Histologiebefund und bestimmter Tumorzellgehalt"
    }, {
      "id": "mii-lm-mtb.Behandlungsepisode.Probe.Histologie",
      "max": "1",
      "min": 0,
      "path": "mii-lm-mtb.Behandlungsepisode.Probe.Histologie",
      "type": [ {
        "code": "Reference",
        "targetProfile": [ "http://hl7.org/fhir/StructureDefinition/DiagnosticReport" ]
      } ],
      "short": "Verweis auf Histologiebefund",
      "mapping": [ {
        "map": "DiagnosticReport",
        "identity": "mii-map-mtb"
      } ],
      "definition": "Verweis auf den Befund zur Histologie des Tumors"
    }, {
      "id": "mii-lm-mtb.Behandlungsepisode.Probe.Tumorzellgehalt",
      "max": "1",
      "min": 0,
      "path": "mii-lm-mtb.Behandlungsepisode.Probe.Tumorzellgehalt",
      "type": [ {
        "code": "BackboneElement"
      } ],
      "short": "Tumorzellgehalt",
      "mapping": [ {
        "map": "Observation",
        "identity": "mii-map-mtb"
      } ],
      "definition": "Tumorzellgehalt"
    }, {
      "id": "mii-lm-mtb.Behandlungsepisode.Probe.Tumorzellgehalt.Methode",
      "max": "1",
      "min": 1,
      "path": "mii-lm-mtb.Behandlungsepisode.Probe.Tumorzellgehalt.Methode",
      "type": [ {
        "code": "code"
      } ],
      "short": "Bestimmungsmethode",
      "mapping": [ {
        "map": "Observation.method.valueCodeableConcept.coding.code",
        "identity": "mii-map-mtb"
      } ],
      "definition": "Angewandte Methode zur Bestimmung des Tumorzellgehalts"
    }, {
      "id": "mii-lm-mtb.Behandlungsepisode.Probe.Tumorzellgehalt.Wert",
      "max": "1",
      "min": 1,
      "path": "mii-lm-mtb.Behandlungsepisode.Probe.Tumorzellgehalt.Wert",
      "type": [ {
        "code": "decimal"
      } ],
      "short": "Anzahl Tumorzellen",
      "mapping": [ {
        "map": "Observation.valueQuantity.value",
        "identity": "mii-map-mtb"
      } ],
      "definition": "Gesamtanzahl an aktiven und inaktiven Tumorzellen"
    }, {
      "id": "mii-lm-mtb.Behandlungsepisode.BeschlussTherapieplan",
      "max": "*",
      "min": 0,
      "path": "mii-lm-mtb.Behandlungsepisode.BeschlussTherapieplan",
      "type": [ {
        "code": "BackboneElement"
      } ],
      "short": "Therapieplan gemäß Beschluss des Molekularen Tumorboards",
      "mapping": [ {
        "map": "CarePlan",
        "identity": "mii-map-mtb"
      } ],
      "definition": "Therapieplan gemäß Beschluss des Molekularen Tumorboards"
    }, {
      "id": "mii-lm-mtb.Behandlungsepisode.BeschlussTherapieplan.Erstellungsdatum",
      "max": "1",
      "min": 0,
      "path": "mii-lm-mtb.Behandlungsepisode.BeschlussTherapieplan.Erstellungsdatum",
      "type": [ {
        "code": "dateTime"
      } ],
      "short": "Erstellungsdatum",
      "mapping": [ {
        "map": "CarePlan.created",
        "identity": "mii-map-mtb"
      } ],
      "definition": "Erstellungsdatum des Therapieplans gemäß Beschluss des Molekularen Tumorboards"
    }, {
      "id": "mii-lm-mtb.Behandlungsepisode.BeschlussTherapieplan.Protokollauszug",
      "max": "1",
      "min": 0,
      "path": "mii-lm-mtb.Behandlungsepisode.BeschlussTherapieplan.Protokollauszug",
      "type": [ {
        "code": "string"
      } ],
      "short": "Protokollauszug",
      "mapping": [ {
        "map": "CarePlan.description",
        "identity": "mii-map-mtb"
      } ],
      "definition": "Protokollauszug aus dem Beschluss des Molekularen Tumorboards"
    }, {
      "id": "mii-lm-mtb.Behandlungsepisode.BeschlussTherapieplan.StatusBegruendung",
      "max": "1",
      "min": 0,
      "path": "mii-lm-mtb.Behandlungsepisode.BeschlussTherapieplan.StatusBegruendung",
      "type": [ {
        "code": "code"
      } ],
      "short": "Status Begründung",
      "mapping": [ {
        "map": "CarePlan.activity.detail.statusReason.valueCodeableConcept.coding.code",
        "identity": "mii-map-mtb"
      } ],
      "definition": "Erforderliche Begründung für den Fall, dass der Beschluss keine Therapieempfehlungen enthält"
    }, {
      "id": "mii-lm-mtb.Behandlungsepisode.BeschlussTherapieplan.Therapieempfehlungen",
      "max": "*",
      "min": 0,
      "path": "mii-lm-mtb.Behandlungsepisode.BeschlussTherapieplan.Therapieempfehlungen",
      "type": [ {
        "code": "BackboneElement"
      } ],
      "short": "Therapieempfehlungen gemäß Beschluss des Molekularen Tumorboards",
      "mapping": [ {
        "map": "MedicationRequest",
        "identity": "mii-map-mtb"
      } ],
      "definition": "Therapieempfehlungen gemäß Beschluss des Molekularen Tumorboards"
    }, {
      "id": "mii-lm-mtb.Behandlungsepisode.BeschlussTherapieplan.Therapieempfehlungen.StuetzendeMolekularAlterationen",
      "max": "*",
      "min": 0,
      "path": "mii-lm-mtb.Behandlungsepisode.BeschlussTherapieplan.Therapieempfehlungen.StuetzendeMolekularAlterationen",
      "type": [ {
        "code": "Reference",
        "targetProfile": [ "http://hl7.org/fhir/StructureDefinition/Observation" ]
      } ],
      "short": "Stützende molekulare Alteration(en)",
      "mapping": [ {
        "map": "MedicationRequest.supportingInformation[StuetzendeMolekulareAlteration]",
        "identity": "mii-map-mtb"
      } ],
      "definition": "Verweis auf entsprechendes Feld in NGS Bericht und/oder IHC (Verweis auf KDS Molekular-Pathologischer Befundbericht)"
    }, {
      "id": "mii-lm-mtb.Behandlungsepisode.BeschlussTherapieplan.Therapieempfehlungen.StuetzendeEntitaet",
      "max": "*",
      "min": 0,
      "path": "mii-lm-mtb.Behandlungsepisode.BeschlussTherapieplan.Therapieempfehlungen.StuetzendeEntitaet",
      "type": [ {
        "code": "Reference",
        "targetProfile": [ "http://hl7.org/fhir/StructureDefinition/Condition" ]
      } ],
      "short": "Stützende Entität",
      "mapping": [ {
        "map": "MedicationRequest.supportingInformation[StuetzendeEntitaet]",
        "identity": "mii-map-mtb"
      } ],
      "definition": "Verweis auf die Tumorentität, falls Therapie- oder Studieneinschlussempfehlung nicht aufgrund einer molekularen Alteration geschieht"
    }, {
      "id": "mii-lm-mtb.Behandlungsepisode.BeschlussTherapieplan.Therapieempfehlungen.Wirkstoffe",
      "max": "*",
      "min": 0,
      "path": "mii-lm-mtb.Behandlungsepisode.BeschlussTherapieplan.Therapieempfehlungen.Wirkstoffe",
      "type": [ {
        "code": "Reference",
        "targetProfile": [ "http://hl7.org/fhir/StructureDefinition/Medication" ]
      } ],
      "short": "Wirkstoffe",
      "mapping": [ {
        "map": "MedicationRequest.medicationReference(Medication)",
        "identity": "mii-map-mtb"
      } ],
      "definition": "Empfohlene Wirkstoffe zur Therapie"
    }, {
      "id": "mii-lm-mtb.Behandlungsepisode.BeschlussTherapieplan.Therapieempfehlungen.Prioritaet",
      "max": "1",
      "min": 0,
      "path": "mii-lm-mtb.Behandlungsepisode.BeschlussTherapieplan.Therapieempfehlungen.Prioritaet",
      "type": [ {
        "code": "positiveInt"
      } ],
      "short": "Priorität",
      "mapping": [ {
        "map": "MedicationRequest.extension(Prioritaet)",
        "identity": "mii-map-mtb"
      } ],
      "definition": "Priorität der (einzelnen) Therapieempfehlung"
    }, {
      "id": "mii-lm-mtb.Behandlungsepisode.BeschlussTherapieplan.Therapieempfehlungen.EvidenzLevel",
      "max": "1",
      "min": 0,
      "path": "mii-lm-mtb.Behandlungsepisode.BeschlussTherapieplan.Therapieempfehlungen.EvidenzLevel",
      "type": [ {
        "code": "BackboneElement"
      } ],
      "short": "Evidenzgraduierung",
      "mapping": [ {
        "map": "Extension",
        "identity": "mii-map-mtb"
      } ],
      "definition": "Evidenzgraduierung für Biomarker-basierte Therapieempfehlung"
    }, {
      "id": "mii-lm-mtb.Behandlungsepisode.BeschlussTherapieplan.Therapieempfehlungen.EvidenzLevel.Graduierung",
      "max": "1",
      "min": 1,
      "path": "mii-lm-mtb.Behandlungsepisode.BeschlussTherapieplan.Therapieempfehlungen.EvidenzLevel.Graduierung",
      "type": [ {
        "code": "code"
      } ],
      "short": "Evidenzgrad",
      "mapping": [ {
        "map": "Extension.valueCodableConcept.coding.code",
        "identity": "mii-map-mtb"
      } ],
      "definition": "Evidenzgrad der Therapieempfehlung"
    }, {
      "id": "mii-lm-mtb.Behandlungsepisode.BeschlussTherapieplan.Therapieempfehlungen.EvidenzLevel.Zusatz",
      "max": "*",
      "min": 0,
      "path": "mii-lm-mtb.Behandlungsepisode.BeschlussTherapieplan.Therapieempfehlungen.EvidenzLevel.Zusatz",
      "type": [ {
        "code": "code"
      } ],
      "short": "Zusatzverweis",
      "mapping": [ {
        "map": "Extension.valueCodableConcept.coding.code",
        "identity": "mii-map-mtb"
      } ],
      "definition": "Zusatzverweise zum Evidenzgrad"
    }, {
      "id": "mii-lm-mtb.Behandlungsepisode.BeschlussTherapieplan.Therapieempfehlungen.EvidenzLevel.Publikationen",
      "max": "*",
      "min": 0,
      "path": "mii-lm-mtb.Behandlungsepisode.BeschlussTherapieplan.Therapieempfehlungen.EvidenzLevel.Publikationen",
      "type": [ {
        "code": "BackboneElement"
      } ],
      "short": "Publikationen",
      "mapping": [ {
        "map": "Extension",
        "identity": "mii-map-mtb"
      } ],
      "definition": "Publikationen zur Evidenzgraduierung"
    }, {
      "id": "mii-lm-mtb.Behandlungsepisode.BeschlussTherapieplan.Therapieempfehlungen.EvidenzLevel.Publikationen.DigitalObjectIdentifier",
      "max": "1",
      "min": 0,
      "path": "mii-lm-mtb.Behandlungsepisode.BeschlussTherapieplan.Therapieempfehlungen.EvidenzLevel.Publikationen.DigitalObjectIdentifier",
      "type": [ {
        "code": "string"
      } ],
      "short": "Digital Object Identifier (DOI)",
      "mapping": [ {
        "map": "Idenfifier.value",
        "identity": "mii-map-mtb"
      } ],
      "definition": "DOI zur Publikation"
    }, {
      "id": "mii-lm-mtb.Behandlungsepisode.BeschlussTherapieplan.Therapieempfehlungen.EvidenzLevel.Publikationen.PubMedIdentifier",
      "max": "1",
      "min": 0,
      "path": "mii-lm-mtb.Behandlungsepisode.BeschlussTherapieplan.Therapieempfehlungen.EvidenzLevel.Publikationen.PubMedIdentifier",
      "type": [ {
        "code": "string"
      } ],
      "short": "PubMed Identifier (PMID)",
      "mapping": [ {
        "map": "Identifier.value",
        "identity": "mii-map-mtb"
      } ],
      "definition": "PMID zur Publikation"
    }, {
      "id": "mii-lm-mtb.Behandlungsepisode.BeschlussTherapieplan.Therapieempfehlungen.Studieneinschlussempfehlungen",
      "max": "*",
      "min": 0,
      "path": "mii-lm-mtb.Behandlungsepisode.BeschlussTherapieplan.Therapieempfehlungen.Studieneinschlussempfehlungen",
      "type": [ {
        "code": "BackboneElement"
      } ],
      "short": "Studieneinschlussempfehlungen",
      "mapping": [ {
        "map": "ResearchStudy",
        "identity": "mii-map-mtb"
      } ],
      "definition": "Empfehlungen zum Studieneinschlus gemäß Beschluss des Molekularen Tumorboards"
    }, {
      "id": "mii-lm-mtb.Behandlungsepisode.BeschlussTherapieplan.Therapieempfehlungen.Studieneinschlussempfehlungen.StuetzendeEntitaet",
      "max": "*",
      "min": 0,
      "path": "mii-lm-mtb.Behandlungsepisode.BeschlussTherapieplan.Therapieempfehlungen.Studieneinschlussempfehlungen.StuetzendeEntitaet",
      "type": [ {
        "code": "code"
      } ],
      "short": "Stützende Entität",
      "mapping": [ {
        "map": "ResearchStudy.condition.extension(Condition)",
        "identity": "mii-map-mtb"
      } ],
      "definition": "Stützende Entität"
    }, {
      "id": "mii-lm-mtb.Behandlungsepisode.BeschlussTherapieplan.Therapieempfehlungen.Studieneinschlussempfehlungen.NctNummer",
      "max": "1",
      "min": 0,
      "path": "mii-lm-mtb.Behandlungsepisode.BeschlussTherapieplan.Therapieempfehlungen.Studieneinschlussempfehlungen.NctNummer",
      "type": [ {
        "code": "Identifier"
      } ],
      "short": "NCT-Nummer",
      "mapping": [ {
        "map": "ResearchStudy.identifier[NCT-Nummer]",
        "identity": "mii-map-mtb"
      } ],
      "definition": "Identifikator NCT Studie"
    }, {
      "id": "mii-lm-mtb.Behandlungsepisode.BeschlussTherapieplan.Therapieempfehlungen.Studieneinschlussempfehlungen.EudraCtNummer",
      "max": "1",
      "min": 0,
      "path": "mii-lm-mtb.Behandlungsepisode.BeschlussTherapieplan.Therapieempfehlungen.Studieneinschlussempfehlungen.EudraCtNummer",
      "type": [ {
        "code": "Identifier"
      } ],
      "short": "Eudra-CT-Nummer",
      "mapping": [ {
        "map": "ResearchStudy.identifier[EudraCT-Nummer]",
        "identity": "mii-map-mtb"
      } ],
      "definition": "Identifikator Eudra-CT Studie"
    }, {
      "id": "mii-lm-mtb.Behandlungsepisode.BeschlussTherapieplan.Therapieempfehlungen.Studieneinschlussempfehlungen.DrksNummer",
      "max": "1",
      "min": 0,
      "path": "mii-lm-mtb.Behandlungsepisode.BeschlussTherapieplan.Therapieempfehlungen.Studieneinschlussempfehlungen.DrksNummer",
      "type": [ {
        "code": "Identifier"
      } ],
      "short": "DRKS-Nummer",
      "mapping": [ {
        "map": "ResearchStudy.identifier[DRKS-Nummer]",
        "identity": "mii-map-mtb"
      } ],
      "definition": "Identifikator DRKS Studie"
    }, {
      "id": "mii-lm-mtb.Behandlungsepisode.BeschlussTherapieplan.RebiopsieAuftrag",
      "max": "*",
      "min": 0,
      "path": "mii-lm-mtb.Behandlungsepisode.BeschlussTherapieplan.RebiopsieAuftrag",
      "type": [ {
        "code": "BackboneElement"
      } ],
      "short": "Auftrag zur Rebiopsie",
      "mapping": [ {
        "map": "ServiceRequest",
        "identity": "mii-map-mtb"
      } ],
      "definition": "Auftrag zur Rebiopsie gemäß Beschluss des Molekularen Tumorboards"
    }, {
      "id": "mii-lm-mtb.Behandlungsepisode.BeschlussTherapieplan.RebiopsieAuftrag.Begruendung",
      "max": "1",
      "min": 0,
      "path": "mii-lm-mtb.Behandlungsepisode.BeschlussTherapieplan.RebiopsieAuftrag.Begruendung",
      "type": [ {
        "code": "code"
      } ],
      "short": "Begründung Auftrag Rebiopsie",
      "mapping": [ {
        "map": "ServiceRequest.reasonCode.valueCodeableConcept.coding.code",
        "identity": "mii-map-mtb"
      } ],
      "definition": "Begründung für die Beauftragung einer erneuten Biopsie"
    }, {
      "id": "mii-lm-mtb.Behandlungsepisode.BeschlussTherapieplan.RebiopsieAuftrag.Probe",
      "max": "*",
      "min": 0,
      "path": "mii-lm-mtb.Behandlungsepisode.BeschlussTherapieplan.RebiopsieAuftrag.Probe",
      "type": [ {
        "code": "BackboneElement"
      } ],
      "short": "Histologie und Tumorzellgehalt",
      "mapping": [ {
        "map": "Specimen",
        "identity": "mii-map-mtb"
      } ],
      "definition": "Histologiebefund und bestimmter Tumorzellgehalt"
    }, {
      "id": "mii-lm-mtb.Behandlungsepisode.BeschlussTherapieplan.RebiopsieAuftrag.Probe.Histologie",
      "max": "1",
      "min": 0,
      "path": "mii-lm-mtb.Behandlungsepisode.BeschlussTherapieplan.RebiopsieAuftrag.Probe.Histologie",
      "type": [ {
        "code": "Reference",
        "targetProfile": [ "http://hl7.org/fhir/StructureDefinition/DiagnosticReport" ]
      } ],
      "short": "Verweis auf Histologiebefund",
      "mapping": [ {
        "map": "DiagnosticReport",
        "identity": "mii-map-mtb"
      } ],
      "definition": "Verweis auf den Befund zur Histologie des Tumors"
    }, {
      "id": "mii-lm-mtb.Behandlungsepisode.BeschlussTherapieplan.RebiopsieAuftrag.Probe.Tumorzellgehalt",
      "max": "1",
      "min": 0,
      "path": "mii-lm-mtb.Behandlungsepisode.BeschlussTherapieplan.RebiopsieAuftrag.Probe.Tumorzellgehalt",
      "type": [ {
        "code": "BackboneElement"
      } ],
      "short": "Tumorzellgehalt",
      "mapping": [ {
        "map": "Observation",
        "identity": "mii-map-mtb"
      } ],
      "definition": "Tumorzellgehalt"
    }, {
      "id": "mii-lm-mtb.Behandlungsepisode.BeschlussTherapieplan.RebiopsieAuftrag.Probe.Tumorzellgehalt.Methode",
      "max": "1",
      "min": 1,
      "path": "mii-lm-mtb.Behandlungsepisode.BeschlussTherapieplan.RebiopsieAuftrag.Probe.Tumorzellgehalt.Methode",
      "type": [ {
        "code": "code"
      } ],
      "short": "Bestimmungsmethode",
      "mapping": [ {
        "map": "Observation.method.valueCodeableConcept.coding.code",
        "identity": "mii-map-mtb"
      } ],
      "definition": "Angewandte Methode zur Bestimmung des Tumorzellgehalts"
    }, {
      "id": "mii-lm-mtb.Behandlungsepisode.BeschlussTherapieplan.RebiopsieAuftrag.Probe.Tumorzellgehalt.Wert",
      "max": "1",
      "min": 1,
      "path": "mii-lm-mtb.Behandlungsepisode.BeschlussTherapieplan.RebiopsieAuftrag.Probe.Tumorzellgehalt.Wert",
      "type": [ {
        "code": "decimal"
      } ],
      "short": "Anzahl Tumorzellen",
      "mapping": [ {
        "map": "Observation.valueQuantity.value",
        "identity": "mii-map-mtb"
      } ],
      "definition": "Gesamtanzahl an aktiven und inaktiven Tumorzellen"
    }, {
      "id": "mii-lm-mtb.Behandlungsepisode.BeschlussTherapieplan.HumangenetischeBeratungAuftrag",
      "max": "1",
      "min": 0,
      "path": "mii-lm-mtb.Behandlungsepisode.BeschlussTherapieplan.HumangenetischeBeratungAuftrag",
      "type": [ {
        "code": "BackboneElement"
      } ],
      "short": "Auftrag zur Human-genetischen Beratung",
      "mapping": [ {
        "map": "ServiceRequest",
        "identity": "mii-map-mtb"
      } ],
      "definition": "Auftrag zur Human-genetischen Beratung"
    }, {
      "id": "mii-lm-mtb.Behandlungsepisode.BeschlussTherapieplan.HumangenetischeBeratungAuftrag.Begruendung",
      "max": "1",
      "min": 0,
      "path": "mii-lm-mtb.Behandlungsepisode.BeschlussTherapieplan.HumangenetischeBeratungAuftrag.Begruendung",
      "type": [ {
        "code": "code"
      } ],
      "short": "Begründung Auftrag Human-genetische-Beratung",
      "mapping": [ {
        "map": "ServiceRequest.reasonCode.valueCodeableConcept.coding.code",
        "identity": "mii-map-mtb"
      } ],
      "definition": "Begründung für die Beauftragung einer erneuten Human-genetischen Beratung"
    }, {
      "id": "mii-lm-mtb.Behandlungsepisode.BeschlussTherapieplan.HistologieReevaluationAuftrag",
      "max": "1",
      "min": 0,
      "path": "mii-lm-mtb.Behandlungsepisode.BeschlussTherapieplan.HistologieReevaluationAuftrag",
      "type": [ {
        "code": "BackboneElement"
      } ],
      "short": "Auftrag zur Histologie-Reevaluation",
      "mapping": [ {
        "map": "ServiceRequest",
        "identity": "mii-map-mtb"
      } ],
      "definition": "Auftrag zur Histologie-Reevaluation gemäß Beschluss des Molekularen Tumorboards"
    }, {
      "id": "mii-lm-mtb.Behandlungsepisode.BeschlussTherapieplan.HistologieReevaluationAuftrag.Begruendung",
      "max": "1",
      "min": 0,
      "path": "mii-lm-mtb.Behandlungsepisode.BeschlussTherapieplan.HistologieReevaluationAuftrag.Begruendung",
      "type": [ {
        "code": "code"
      } ],
      "short": "Begründung Auftrag Histologie-Reevaluation",
      "mapping": [ {
        "map": "ServiceRequest.reasonCode.valueCodeableConcept.coding.code",
        "identity": "mii-map-mtb"
      } ],
      "definition": "Begründung für die Beauftragung einer erneuten Histologie-Evaluation"
    }, {
      "id": "mii-lm-mtb.Behandlungsepisode.BeschlussTherapieplan.HistologieReevaluationAuftrag.Probe",
      "max": "*",
      "min": 0,
      "path": "mii-lm-mtb.Behandlungsepisode.BeschlussTherapieplan.HistologieReevaluationAuftrag.Probe",
      "type": [ {
        "code": "BackboneElement"
      } ],
      "short": "Histologie und Tumorzellgehalt",
      "mapping": [ {
        "map": "Specimen",
        "identity": "mii-map-mtb"
      } ],
      "definition": "Histologiebefund und bestimmter Tumorzellgehalt"
    }, {
      "id": "mii-lm-mtb.Behandlungsepisode.BeschlussTherapieplan.HistologieReevaluationAuftrag.Probe.Histologie",
      "max": "1",
      "min": 0,
      "path": "mii-lm-mtb.Behandlungsepisode.BeschlussTherapieplan.HistologieReevaluationAuftrag.Probe.Histologie",
      "type": [ {
        "code": "Reference",
        "targetProfile": [ "http://hl7.org/fhir/StructureDefinition/DiagnosticReport" ]
      } ],
      "short": "Verweis auf Histologiebefund",
      "mapping": [ {
        "map": "DiagnosticReport",
        "identity": "mii-map-mtb"
      } ],
      "definition": "Verweis auf den Befund zur Histologie des Tumors"
    }, {
      "id": "mii-lm-mtb.Behandlungsepisode.BeschlussTherapieplan.HistologieReevaluationAuftrag.Probe.Tumorzellgehalt",
      "max": "1",
      "min": 0,
      "path": "mii-lm-mtb.Behandlungsepisode.BeschlussTherapieplan.HistologieReevaluationAuftrag.Probe.Tumorzellgehalt",
      "type": [ {
        "code": "BackboneElement"
      } ],
      "short": "Tumorzellgehalt",
      "mapping": [ {
        "map": "Observation",
        "identity": "mii-map-mtb"
      } ],
      "definition": "Tumorzellgehalt"
    }, {
      "id": "mii-lm-mtb.Behandlungsepisode.BeschlussTherapieplan.HistologieReevaluationAuftrag.Probe.Tumorzellgehalt.Methode",
      "max": "1",
      "min": 1,
      "path": "mii-lm-mtb.Behandlungsepisode.BeschlussTherapieplan.HistologieReevaluationAuftrag.Probe.Tumorzellgehalt.Methode",
      "type": [ {
        "code": "code"
      } ],
      "short": "Bestimmungsmethode",
      "mapping": [ {
        "map": "Observation.method.valueCodeableConcept.coding.code",
        "identity": "mii-map-mtb"
      } ],
      "definition": "Angewandte Methode zur Bestimmung des Tumorzellgehalts"
    }, {
      "id": "mii-lm-mtb.Behandlungsepisode.BeschlussTherapieplan.HistologieReevaluationAuftrag.Probe.Tumorzellgehalt.Wert",
      "max": "1",
      "min": 1,
      "path": "mii-lm-mtb.Behandlungsepisode.BeschlussTherapieplan.HistologieReevaluationAuftrag.Probe.Tumorzellgehalt.Wert",
      "type": [ {
        "code": "decimal"
      } ],
      "short": "Anzahl Tumorzellen",
      "mapping": [ {
        "map": "Observation.valueQuantity.value",
        "identity": "mii-map-mtb"
      } ],
      "definition": "Gesamtanzahl an aktiven und inaktiven Tumorzellen"
    }, {
      "id": "mii-lm-mtb.FollowUp",
      "max": "*",
      "min": 0,
      "path": "mii-lm-mtb.FollowUp",
      "type": [ {
        "code": "BackboneElement"
      } ],
      "short": "Follow-Up nach DNPM",
      "mapping": [ {
        "map": "ClinicalImpression",
        "identity": "mii-map-mtb"
      } ],
      "definition": "Follow-Up nach DNPM"
    }, {
      "id": "mii-lm-mtb.FollowUp.Erfassungsdatum",
      "max": "1",
      "min": 0,
      "path": "mii-lm-mtb.FollowUp.Erfassungsdatum",
      "type": [ {
        "code": "dateTime"
      } ],
      "short": "Erfassungsdatum",
      "mapping": [ {
        "map": "ClinicalImpression.effective",
        "identity": "mii-map-mtb"
      } ],
      "definition": "Erfassungsdatum Durchführung Follow-Up"
    }, {
      "id": "mii-lm-mtb.FollowUp.FollowUpStatus",
      "max": "1",
      "min": 1,
      "path": "mii-lm-mtb.FollowUp.FollowUpStatus",
      "type": [ {
        "code": "code"
      } ],
      "short": "FollowUpStatus",
      "mapping": [ {
        "map": "ClinicalImpression.status",
        "identity": "mii-map-mtb"
      } ],
      "definition": "FollowUpStatus"
    }, {
      "id": "mii-lm-mtb.FollowUp.GrundNichtUmsetzung",
      "max": "1",
      "min": 0,
      "path": "mii-lm-mtb.FollowUp.GrundNichtUmsetzung",
      "type": [ {
        "code": "code"
      } ],
      "short": "GrundNichtUmsetzung",
      "mapping": [ {
        "map": "ClinicalImpression.statusReason",
        "identity": "mii-map-mtb"
      } ],
      "definition": "Grund für die Nicht-Umsetzung des gesamten Therapieplans. Wird entweder evaluiert, wenn Patient ein zweites mal im MTB vorgestellt wird oder Patient verstorben ist."
    }, {
      "id": "mii-lm-mtb.FollowUp.SystemischeTherapie",
      "max": "*",
      "min": 0,
      "path": "mii-lm-mtb.FollowUp.SystemischeTherapie",
      "type": [ {
        "code": "BackboneElement"
      } ],
      "short": "Systemische Therapie nach DNPM",
      "mapping": [ {
        "map": "ClinicalImpression.supportingInfo[UmgesetzteTherapien]",
        "identity": "mii-map-mtb"
      } ],
      "definition": "Systemische Therapie nach DNPM"
    }, {
      "id": "mii-lm-mtb.FollowUp.SystemischeTherapie.MTBTherapieStartdatum",
      "max": "1",
      "min": 0,
      "path": "mii-lm-mtb.FollowUp.SystemischeTherapie.MTBTherapieStartdatum",
      "type": [ {
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      "short": "Systemische Therapie Ende Grund",
      "definition": "Gibt den Grund an, warum die Systemtherapie beendet wurde."
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      "definition": "Referenz auf Therapieempfehlung in Therapieplan"
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      "path": "mii-lm-mtb.FollowUp.SystemischeTherapie.Status",
      "type": [ {
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      "short": "Status",
      "definition": "WENN STATUS COMPLETED ODER STOPPED -> SYSTEMISCHE THERAPIE ENDE GRUND AUSFÜLLEN"
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      "definition": "Response Befund"
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      "definition": "Response Beurteilung"
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      "short": "Zeitpunkt",
      "definition": "Zeitpunkt des Response Befundes"
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      "definition": "Kostenuebernahme Follow-Up"
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      "definition": "Ausstellungsdatum Antrag Kostenübernahme"
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      "short": "Therapie Empfehlung",
      "definition": "Referenz MTB Empfehlung"
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      "short": "Antragsstadium",
      "definition": "Antragsstadium"
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      "short": "Antragssteller ZPM Geschäftsstelle",
      "definition": "Antragssteller ZPM Geschäftsstelle"
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      "definition": "Antwort Kostenuebernahme Follow-Up"
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      "short": "Datum",
      "definition": "Datum"
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      "short": "Antrag",
      "definition": "Antrag"
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      "definition": "Grund"
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      "short": "NGS-Bericht",
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      "definition": "NGS-Bericht"
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      "short": "Erstellungsdatum",
      "mapping": [ {
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        "identity": "mii-map-mtb"
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      "definition": "Erstellungsdatum für den NGS-Bericht"
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      "short": "Probe",
      "mapping": [ {
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        "identity": "mii-map-mtb"
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      "definition": "Referenz zur zugehörigen Probe"
    }, {
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      "short": "Tumor Mutational Burden (TMB)",
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      "definition": "Tumor Mutational Burden (TMB)"
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      "definition": "Interpretation"
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      "definition": "Wert"
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      "definition": "Metadaten"
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      "short": "BRCAness",
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      "definition": "Wert"
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      "definition": "Micro-Satellite Instabilities"
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      "id": "mii-lm-mtb.NGSBericht.EinfacheVariante.AllelicFrequency",
      "max": "1",
      "min": 1,
      "path": "mii-lm-mtb.NGSBericht.EinfacheVariante.AllelicFrequency",
      "type": [ {
        "code": "decimal"
      } ],
      "short": "Allelic Frequency",
      "mapping": [ {
        "map": "MII_PR_MTB_Einfache_Variante.",
        "identity": "mii-map-mtb"
      } ],
      "definition": "Allelic Frequency"
    }, {
      "id": "mii-lm-mtb.NGSBericht.EinfacheVariante.COSMICID",
      "max": "1",
      "min": 1,
      "path": "mii-lm-mtb.NGSBericht.EinfacheVariante.COSMICID",
      "type": [ {
        "code": "integer"
      } ],
      "short": "COSMIC ID",
      "mapping": [ {
        "map": "MII_PR_MTB_Einfache_Variante.",
        "identity": "mii-map-mtb"
      } ],
      "definition": "COSMIC ID"
    }, {
      "id": "mii-lm-mtb.NGSBericht.EinfacheVariante.dbSNPID",
      "max": "1",
      "min": 1,
      "path": "mii-lm-mtb.NGSBericht.EinfacheVariante.dbSNPID",
      "type": [ {
        "code": "integer"
      } ],
      "short": "dbSNP ID",
      "mapping": [ {
        "map": "MII_PR_MTB_Einfache_Variante.",
        "identity": "mii-map-mtb"
      } ],
      "definition": "dbSNP ID"
    }, {
      "id": "mii-lm-mtb.NGSBericht.EinfacheVariante.Interpretation",
      "max": "1",
      "min": 1,
      "path": "mii-lm-mtb.NGSBericht.EinfacheVariante.Interpretation",
      "type": [ {
        "code": "code"
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      "short": "Interpretation",
      "mapping": [ {
        "map": "MII_PR_MTB_Einfache_Variante.",
        "identity": "mii-map-mtb"
      } ],
      "definition": "Interpretation"
    }, {
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      "max": "*",
      "min": 0,
      "path": "mii-lm-mtb.NGSBericht.CopyNumberVariant",
      "type": [ {
        "code": "BackboneElement"
      } ],
      "short": "Einfache Variante",
      "mapping": [ {
        "map": "MII_PR_MolGen_Variante",
        "identity": "mii-map-mtb"
      } ],
      "definition": "Einfache Variante"
    }, {
      "id": "mii-lm-mtb.NGSBericht.CopyNumberVariant.Chromosom",
      "max": "1",
      "min": 1,
      "path": "mii-lm-mtb.NGSBericht.CopyNumberVariant.Chromosom",
      "type": [ {
        "code": "code"
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      "short": "Chromosom",
      "mapping": [ {
        "map": "MII_PR_MolGen_Variante.component[chromosome-identifier]",
        "identity": "mii-map-mtb"
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      "definition": "Chromosom"
    }, {
      "id": "mii-lm-mtb.NGSBericht.CopyNumberVariant.StartPositionsbereich",
      "max": "1",
      "min": 1,
      "path": "mii-lm-mtb.NGSBericht.CopyNumberVariant.StartPositionsbereich",
      "type": [ {
        "code": "integer"
      } ],
      "short": "Start-Positionsbereich",
      "mapping": [ {
        "map": "MII_PR_MolGen_Variante.component[exact-start-end].low",
        "identity": "mii-map-mtb"
      } ],
      "definition": "Start-Positionsbereich"
    }, {
      "id": "mii-lm-mtb.NGSBericht.CopyNumberVariant.EndePositionsbereich",
      "max": "1",
      "min": 1,
      "path": "mii-lm-mtb.NGSBericht.CopyNumberVariant.EndePositionsbereich",
      "type": [ {
        "code": "integer"
      } ],
      "short": "Ende-Positionsbereich",
      "mapping": [ {
        "map": "MII_PR_MolGen_Variante.component[exact-start-end].high",
        "identity": "mii-map-mtb"
      } ],
      "definition": "Ende-Positionsbereich"
    }, {
      "id": "mii-lm-mtb.NGSBericht.CopyNumberVariant.TotalCN",
      "max": "1",
      "min": 1,
      "path": "mii-lm-mtb.NGSBericht.CopyNumberVariant.TotalCN",
      "type": [ {
        "code": "integer"
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      "short": "Total CN",
      "mapping": [ {
        "map": "MII_PR_MolGen_Variante.component[copy-number]",
        "identity": "mii-map-mtb"
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      "definition": "Total CN"
    }, {
      "id": "mii-lm-mtb.NGSBericht.CopyNumberVariant.RelativeCN",
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      "path": "mii-lm-mtb.NGSBericht.CopyNumberVariant.RelativeCN",
      "type": [ {
        "code": "string"
      } ],
      "short": "Relative CN",
      "mapping": [ {
        "map": "MII_PR_MolGen_Variante.component[relative-copy-number]",
        "identity": "mii-map-mtb"
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      "definition": "Relative CN"
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      "id": "mii-lm-mtb.NGSBericht.CopyNumberVariant.CNA",
      "max": "1",
      "min": 1,
      "path": "mii-lm-mtb.NGSBericht.CopyNumberVariant.CNA",
      "type": [ {
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      "short": "CNA",
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        "map": "MII_PR_MolGen_Variante.component[cna]",
        "identity": "mii-map-mtb"
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      "definition": "CNA"
    }, {
      "id": "mii-lm-mtb.NGSBericht.CopyNumberVariant.CNB",
      "max": "1",
      "min": 1,
      "path": "mii-lm-mtb.NGSBericht.CopyNumberVariant.CNB",
      "type": [ {
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      "short": "CNB",
      "mapping": [ {
        "map": "MII_PR_MolGen_Variante.component[cnb]",
        "identity": "mii-map-mtb"
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      "definition": "CNB"
    }, {
      "id": "mii-lm-mtb.NGSBericht.CopyNumberVariant.ReportedAffectedGenes",
      "max": "1",
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      "path": "mii-lm-mtb.NGSBericht.CopyNumberVariant.ReportedAffectedGenes",
      "type": [ {
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      "short": "Reported Affected Genes",
      "mapping": [ {
        "map": "MII_PR_MolGen_Variante.component[gene-studied]",
        "identity": "mii-map-mtb"
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      "definition": "Reported Affected Genes"
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      "id": "mii-lm-mtb.NGSBericht.CopyNumberVariant.ReportedFocality",
      "max": "1",
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      "type": [ {
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      } ],
      "short": "Reported Focality",
      "mapping": [ {
        "map": "MII_PR_MolGen_Variante.component[reported-focality]",
        "identity": "mii-map-mtb"
      } ],
      "definition": "Reported Focality"
    }, {
      "id": "mii-lm-mtb.NGSBericht.CopyNumberVariant.Type",
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      "path": "mii-lm-mtb.NGSBericht.CopyNumberVariant.Type",
      "type": [ {
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      "short": "Type",
      "mapping": [ {
        "map": "MII_PR_MolGen_Variante.component[cnv-type]",
        "identity": "mii-map-mtb"
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      "definition": "Type"
    }, {
      "id": "mii-lm-mtb.NGSBericht.CopyNumberVariant.CopyNumberNeutralLoH",
      "max": "1",
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      "type": [ {
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      "short": "Copy-Number-Neutral LoH",
      "mapping": [ {
        "map": "MII_PR_MolGen_Variante.component[copy-number-neutral-loh]",
        "identity": "mii-map-mtb"
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      "definition": "Copy-Number-Neutral LoH"
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      "id": "mii-lm-mtb.NGSBericht.DNAFusion",
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      "path": "mii-lm-mtb.NGSBericht.DNAFusion",
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      "short": "DNA Fusion",
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        "identity": "mii-map-mtb"
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      "definition": "DNA Fusion"
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      "type": [ {
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      "short": "5' Domain",
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      "definition": "5' Domain"
    }, {
      "id": "mii-lm-mtb.NGSBericht.DNAFusion.ThreePrimeDomain",
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      "path": "mii-lm-mtb.NGSBericht.DNAFusion.ThreePrimeDomain",
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      "short": "3' Domain",
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        "map": "MII_PR_MTB_DNA_Fusion.component[three-prime-gene]",
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      "definition": "3' Domain"
    }, {
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      "short": "Number Reported Reads",
      "mapping": [ {
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      "definition": "Number Reported Reads"
    }, {
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      "short": "RNA Fusion",
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      "definition": "RNA Fusion"
    }, {
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      "short": "5' Fusion Partner",
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        "map": "MII_PR_MTB_RNA_Fusion.component[five-prime-strand]",
        "identity": "mii-map-mtb"
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      "definition": "5' Fusion Partner"
    }, {
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      "type": [ {
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      "short": "3' Fusion Partner",
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        "map": "MII_PR_MTB_RNA_Fusion.component[three-prime-strand]",
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      "definition": "3' Fusion Partner"
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      "path": "mii-lm-mtb.NGSBericht.RNAFusion.Effect",
      "type": [ {
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      "short": "Effect",
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        "map": "MII_PR_MTB_RNA_Fusion.component[effect]",
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      "definition": "Effect"
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      "path": "mii-lm-mtb.NGSBericht.RNAFusion.COSMICID",
      "type": [ {
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      "mapping": [ {
        "map": "MII_PR_MTB_RNA_Fusion.component[cosmic-id]",
        "identity": "mii-map-mtb"
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      "definition": "COSMIC ID"
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      "id": "mii-lm-mtb.NGSBericht.RNAFusion.NumberReportedReads",
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      "short": "Number Reported Reads",
      "mapping": [ {
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      "definition": "Number Reported Reads"
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      "id": "mii-lm-mtb.NGSBericht.RNASeq",
      "max": "*",
      "min": 0,
      "path": "mii-lm-mtb.NGSBericht.RNASeq",
      "type": [ {
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      "short": "RNA Fusion",
      "mapping": [ {
        "map": "",
        "identity": "mii-map-mtb"
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      "definition": "RNA Fusion"
    }, {
      "id": "mii-lm-mtb.NGSBericht.RNASeq.VariantenId",
      "max": "1",
      "min": 0,
      "path": "mii-lm-mtb.NGSBericht.RNASeq.VariantenId",
      "type": [ {
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      "short": "Varianten ID",
      "mapping": [ {
        "map": "",
        "identity": "mii-map-mtb"
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      "definition": "Varianten ID"
    }, {
      "id": "mii-lm-mtb.NGSBericht.RNASeq.EntrezID",
      "max": "1",
      "min": 0,
      "path": "mii-lm-mtb.NGSBericht.RNASeq.EntrezID",
      "type": [ {
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      "short": "Entrez ID",
      "mapping": [ {
        "map": "",
        "identity": "mii-map-mtb"
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      "definition": "Entrez ID"
    }, {
      "id": "mii-lm-mtb.NGSBericht.RNASeq.EnsembleID",
      "max": "1",
      "min": 0,
      "path": "mii-lm-mtb.NGSBericht.RNASeq.EnsembleID",
      "type": [ {
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        "identity": "mii-map-mtb"
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      "definition": "Ensemble ID"
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      "id": "mii-lm-mtb.NGSBericht.RNASeq.Gen",
      "max": "1",
      "min": 0,
      "path": "mii-lm-mtb.NGSBericht.RNASeq.Gen",
      "type": [ {
        "code": "Reference"
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      "short": "Gen",
      "mapping": [ {
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        "identity": "mii-map-mtb"
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      "definition": "Gen"
    }, {
      "id": "mii-lm-mtb.NGSBericht.RNASeq.TranscriptID",
      "max": "1",
      "min": 0,
      "path": "mii-lm-mtb.NGSBericht.RNASeq.TranscriptID",
      "type": [ {
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      "short": "Transcript ID",
      "mapping": [ {
        "map": "",
        "identity": "mii-map-mtb"
      } ],
      "definition": "Transcript ID"
    }, {
      "id": "mii-lm-mtb.NGSBericht.RNASeq.TranscriptsPerMillion",
      "max": "1",
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      "path": "mii-lm-mtb.NGSBericht.RNASeq.TranscriptsPerMillion",
      "type": [ {
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      "short": "Transcripts Per Million",
      "mapping": [ {
        "map": "",
        "identity": "mii-map-mtb"
      } ],
      "definition": "Transcripts Per Million"
    }, {
      "id": "mii-lm-mtb.NGSBericht.RNASeq.TissueCorrectedExpression",
      "max": "1",
      "min": 0,
      "path": "mii-lm-mtb.NGSBericht.RNASeq.TissueCorrectedExpression",
      "type": [ {
        "code": "boolean"
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      "short": "Tissue Corrected Expression",
      "mapping": [ {
        "map": "",
        "identity": "mii-map-mtb"
      } ],
      "definition": "Tissue Corrected Expression"
    }, {
      "id": "mii-lm-mtb.NGSBericht.RNASeq.RawCounts",
      "max": "1",
      "min": 0,
      "path": "mii-lm-mtb.NGSBericht.RNASeq.RawCounts",
      "type": [ {
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      "short": "Raw counts",
      "mapping": [ {
        "map": "",
        "identity": "mii-map-mtb"
      } ],
      "definition": "Raw counts"
    }, {
      "id": "mii-lm-mtb.NGSBericht.RNASeq.LibrarySize",
      "max": "1",
      "min": 0,
      "path": "mii-lm-mtb.NGSBericht.RNASeq.LibrarySize",
      "type": [ {
        "code": "integer"
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      "short": "Library size",
      "mapping": [ {
        "map": "",
        "identity": "mii-map-mtb"
      } ],
      "definition": "Library size"
    }, {
      "id": "mii-lm-mtb.NGSBericht.RNASeq.CohortRanking",
      "max": "1",
      "min": 0,
      "path": "mii-lm-mtb.NGSBericht.RNASeq.CohortRanking",
      "type": [ {
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      "short": "Cohort ranking",
      "mapping": [ {
        "map": "",
        "identity": "mii-map-mtb"
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      "definition": "Cohort ranking"
    } ]
  },
  "contact": [ {
    "telecom": [ {
      "value": "https://www.medizininformatik-initiative.de",
      "system": "url"
    } ]
  } ],
  "baseDefinition": "http://hl7.org/fhir/StructureDefinition/Element"
}