{
  "description": "Dieses Profil beschreibt die Gesamtzahl der in der DNA von Krebszellen gefundenen Mutationen.",
  "_filename": "fsh-generated/resources/StructureDefinition-mii-pr-molgen-mutationslast.json",
  "package_name": "de.medizininformatikinitiative.kerndatensatz.molgen",
  "date": null,
  "derivation": "constraint",
  "publisher": "Medizininformatik Initiative",
  "fhirVersion": "4.0.1",
  "name": "MII_PR_MolGen_Mutationslast",
  "mapping": [ {
    "name": "MII KDS Mapping",
    "identity": "MII-KDS"
  } ],
  "abstract": false,
  "type": "Observation",
  "experimental": null,
  "resourceType": "StructureDefinition",
  "title": "MII PR MolGen Mutationslast",
  "package_version": "2026.0.1",
  "status": "active",
  "id": "80752ff5-9c4d-471f-9280-e132e0c14d5e",
  "kind": "resource",
  "url": "https://www.medizininformatik-initiative.de/fhir/ext/modul-molgen/StructureDefinition/mutationslast",
  "version": "2026.0.1",
  "differential": {
    "element": [ {
      "id": "Observation.status",
      "path": "Observation.status",
      "short": "Status",
      "_short": {
        "extension": [ {
          "url": "http://hl7.org/fhir/StructureDefinition/translation",
          "extension": [ {
            "url": "lang",
            "valueCode": "de-DE"
          }, {
            "url": "content",
            "valueString": "Status"
          } ]
        } ]
      },
      "definition": "Status der Beobachtung",
      "_definition": {
        "extension": [ {
          "url": "http://hl7.org/fhir/StructureDefinition/translation",
          "extension": [ {
            "url": "lang",
            "valueCode": "de-DE"
          }, {
            "url": "content",
            "valueString": "Status der Beobachtung"
          } ]
        } ]
      },
      "mustSupport": true
    }, {
      "id": "Observation.code",
      "path": "Observation.code",
      "definition": "Code zur Identifizierung der Mutationslast",
      "_definition": {
        "extension": [ {
          "url": "http://hl7.org/fhir/StructureDefinition/translation",
          "extension": [ {
            "url": "lang",
            "valueCode": "de-DE"
          }, {
            "url": "content",
            "valueString": "Code zur Identifizierung der Mutationslast"
          } ]
        } ]
      }
    }, {
      "id": "Observation.subject",
      "min": 1,
      "path": "Observation.subject"
    }, {
      "id": "Observation.value[x]",
      "path": "Observation.value[x]",
      "short": "Ergebniswert",
      "_short": {
        "extension": [ {
          "url": "http://hl7.org/fhir/StructureDefinition/translation",
          "extension": [ {
            "url": "lang",
            "valueCode": "de-DE"
          }, {
            "url": "content",
            "valueString": "Ergebniswert"
          } ]
        } ]
      },
      "slicing": {
        "rules": "open",
        "ordered": false,
        "discriminator": [ {
          "path": "$this",
          "type": "type"
        } ]
      },
      "definition": "Der numerische Wert der Mutationslast in Mutationen pro Megabase",
      "_definition": {
        "extension": [ {
          "url": "http://hl7.org/fhir/StructureDefinition/translation",
          "extension": [ {
            "url": "lang",
            "valueCode": "de-DE"
          }, {
            "url": "content",
            "valueString": "Der numerische Wert der Mutationslast in Mutationen pro Megabase"
          } ]
        } ]
      },
      "mustSupport": true
    }, {
      "id": "Observation.value[x]:valueQuantity",
      "max": "1",
      "min": 0,
      "path": "Observation.value[x]",
      "type": [ {
        "code": "Quantity"
      } ],
      "mapping": [ {
        "map": "mide-dataelement-2012",
        "comment": "Mutationslast",
        "identity": "MII-KDS"
      } ],
      "sliceName": "valueQuantity"
    }, {
      "id": "Observation.specimen",
      "path": "Observation.specimen",
      "short": "Probe",
      "_short": {
        "extension": [ {
          "url": "http://hl7.org/fhir/StructureDefinition/translation",
          "extension": [ {
            "url": "lang",
            "valueCode": "de-DE"
          }, {
            "url": "content",
            "valueString": "Probe"
          } ]
        } ]
      },
      "definition": "Die untersuchte Tumorprobe",
      "_definition": {
        "extension": [ {
          "url": "http://hl7.org/fhir/StructureDefinition/translation",
          "extension": [ {
            "url": "lang",
            "valueCode": "de-DE"
          }, {
            "url": "content",
            "valueString": "Die untersuchte Tumorprobe"
          } ]
        } ]
      },
      "mustSupport": true
    } ]
  },
  "contact": [ {
    "telecom": [ {
      "value": "https://www.medizininformatik-initiative.de",
      "system": "url"
    } ]
  } ],
  "baseDefinition": "https://www.medizininformatik-initiative.de/fhir/ext/modul-molgen/StructureDefinition/mii-pr-molgen-molekularer-biomarker"
}