{
  "description": "NGS-Bericht zu einer Probe",
  "_filename": "StructureDefinition-mii-pr-mtb-ngs-bericht.json",
  "package_name": "de.medizininformatikinitiative.kerndatensatz.mtb",
  "date": null,
  "derivation": "constraint",
  "publisher": "Medizininformatik Initiative",
  "fhirVersion": "4.0.1",
  "name": "MII_PR_MTB_NGS_Bericht",
  "abstract": false,
  "type": "DiagnosticReport",
  "experimental": null,
  "resourceType": "StructureDefinition",
  "title": "MII PR MTB NGS-Bericht",
  "package_version": "2025.0.0-ballot",
  "status": "draft",
  "id": "ff860066-f859-47c2-81f8-7d7e45c96d49",
  "kind": "resource",
  "url": "https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-pr-mtb-ngs-bericht",
  "version": "2024.0.0-ballot",
  "differential": {
    "element": [ {
      "id": "DiagnosticReport.meta",
      "path": "DiagnosticReport.meta",
      "mustSupport": true
    }, {
      "id": "DiagnosticReport.meta.profile",
      "path": "DiagnosticReport.meta.profile",
      "mustSupport": true
    }, {
      "id": "DiagnosticReport.subject",
      "path": "DiagnosticReport.subject",
      "type": [ {
        "code": "Reference",
        "targetProfile": [ "http://hl7.org/fhir/StructureDefinition/Patient" ]
      } ],
      "short": "Referenz auf Patient",
      "mustSupport": true
    }, {
      "id": "DiagnosticReport.issued",
      "path": "DiagnosticReport.issued",
      "short": "Erstellungsdatum",
      "mustSupport": true
    }, {
      "id": "DiagnosticReport.specimen",
      "path": "DiagnosticReport.specimen",
      "type": [ {
        "code": "Reference",
        "targetProfile": [ "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-specimen", "https://www.medizininformatik-initiative.de/fhir/ext/modul-patho/StructureDefinition/mii-pr-patho-specimen", "https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Specimen", "http://hl7.org/fhir/StructureDefinition/Specimen" ]
      } ],
      "short": "Referenz auf Probe",
      "mustSupport": true
    }, {
      "id": "DiagnosticReport.result",
      "path": "DiagnosticReport.result",
      "slicing": {
        "rules": "open",
        "ordered": false,
        "description": "Slice für Varianten & Biomarker des NGS-Berichts",
        "discriminator": [ {
          "path": "$this.resolve()",
          "type": "profile"
        } ]
      }
    }, {
      "path": "DiagnosticReport.result",
      "min": 0,
      "definition": "Verweis auf Tumor Mutational Burden",
      "short": "Tumor Mutational Burden",
      "type": [ {
        "code": "Reference",
        "targetProfile": [ "https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-pr-mtb-mutationslast" ]
      } ],
      "mustSupport": true,
      "sliceName": "TumorMutionalBurden",
      "max": "1",
      "id": "DiagnosticReport.result:TumorMutionalBurden"
    }, {
      "path": "DiagnosticReport.result",
      "min": 0,
      "definition": "Verweis auf Micro-Satellite Instabilities",
      "short": "Micro-Satellite Instabilities",
      "type": [ {
        "code": "Reference",
        "targetProfile": [ "https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-pr-mtb-mikrosatelliteninstabilitaet" ]
      } ],
      "mustSupport": true,
      "sliceName": "MSI",
      "max": "1",
      "id": "DiagnosticReport.result:MSI"
    }, {
      "path": "DiagnosticReport.result",
      "min": 0,
      "definition": "Ploidie",
      "short": "Ploidie",
      "type": [ {
        "code": "Reference",
        "targetProfile": [ "https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-pr-mtb-ploidie" ]
      } ],
      "mustSupport": true,
      "sliceName": "Ploidie",
      "max": "1",
      "id": "DiagnosticReport.result:Ploidie"
    }, {
      "path": "DiagnosticReport.result",
      "min": 0,
      "definition": "Verweis auf HRD-Score",
      "short": "HRD-Score",
      "type": [ {
        "code": "Reference",
        "targetProfile": [ "https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-pr-mtb-hrd-score" ]
      } ],
      "mustSupport": true,
      "sliceName": "HRDScore",
      "max": "1",
      "id": "DiagnosticReport.result:HRDScore"
    }, {
      "path": "DiagnosticReport.result",
      "min": 0,
      "definition": "Verweis auf BRCAness",
      "short": "BRCAness",
      "type": [ {
        "code": "Reference",
        "targetProfile": [ "https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-pr-mtb-brcaness" ]
      } ],
      "mustSupport": true,
      "sliceName": "BRCAness",
      "max": "1",
      "id": "DiagnosticReport.result:BRCAness"
    }, {
      "path": "DiagnosticReport.result",
      "min": 0,
      "definition": "Verweis auf Einfache Variante",
      "short": "Einfache Variante",
      "type": [ {
        "code": "Reference",
        "targetProfile": [ "https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-pr-mtb-einfache-variante" ]
      } ],
      "mustSupport": true,
      "sliceName": "EinfacheVariante",
      "max": "1",
      "id": "DiagnosticReport.result:EinfacheVariante"
    }, {
      "path": "DiagnosticReport.result",
      "min": 0,
      "definition": "Verweis auf Copy Number Variant",
      "short": "Copy Number Variant",
      "type": [ {
        "code": "Reference",
        "targetProfile": [ "https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-pr-mtb-copy-number-variant" ]
      } ],
      "mustSupport": true,
      "sliceName": "CopyNumberVariant",
      "max": "1",
      "id": "DiagnosticReport.result:CopyNumberVariant"
    }, {
      "path": "DiagnosticReport.result",
      "min": 0,
      "definition": "Verweis auf DNA-Fusion",
      "short": "DNA-Fusion",
      "type": [ {
        "code": "Reference",
        "targetProfile": [ "https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-pr-mtb-dna-fusion" ]
      } ],
      "mustSupport": true,
      "sliceName": "DNAFusion",
      "max": "1",
      "id": "DiagnosticReport.result:DNAFusion"
    }, {
      "path": "DiagnosticReport.result",
      "min": 0,
      "definition": "Verweis auf RNA-Fusion",
      "short": "RNA-Fusion",
      "type": [ {
        "code": "Reference",
        "targetProfile": [ "https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-pr-mtb-rna-fusion" ]
      } ],
      "mustSupport": true,
      "sliceName": "RNAFusion",
      "max": "1",
      "id": "DiagnosticReport.result:RNAFusion"
    }, {
      "path": "DiagnosticReport.result",
      "min": 0,
      "definition": "Verweis auf RNASeq",
      "short": "RNASeq",
      "type": [ {
        "code": "Reference",
        "targetProfile": [ "https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-pr-mtb-rna-seq" ]
      } ],
      "mustSupport": true,
      "sliceName": "RNASeq",
      "max": "1",
      "id": "DiagnosticReport.result:RNASeq"
    }, {
      "id": "DiagnosticReport.result:Tumorzellgehalt",
      "max": "1",
      "min": 0,
      "path": "DiagnosticReport.result",
      "sliceName": "Tumorzellgehalt",
      "mustSupport": true
    } ]
  },
  "contact": [ {
    "telecom": [ {
      "value": "https://www.medizininformatik-initiative.de",
      "system": "url"
    } ]
  } ],
  "baseDefinition": "http://hl7.org/fhir/StructureDefinition/DiagnosticReport"
}