{
  "description": "Codesystem für Her2neu Status basierend auf der S3-Leitlinie Mammakarzinom und ASCO/CAP Guidelines mit erweiterten Klassifikationen (HER2-low, HER2-ultralow)",
  "_filename": "CodeSystem-mii-cs-onko-mamma-her2neu-status-leitlinie.json",
  "package_name": "de.medizininformatikinitiative.kerndatensatz.onkologie",
  "date": "2025-11-13T17:19:39+01:00",
  "meta": {
    "profile": [ "http://hl7.org/fhir/StructureDefinition/shareablecodesystem" ]
  },
  "publisher": "Medizininformatik Initiative",
  "content": "complete",
  "name": "MII_CS_Onko_Mamma_Her2neu_Status_Leitlinie",
  "type": null,
  "experimental": "false",
  "resourceType": "CodeSystem",
  "title": "MII CS Onkologie Mamma Her2neu Status Leitlinie",
  "package_version": "2026.0.0-rc.5",
  "status": "active",
  "id": "fcaff4b2-f6ba-4410-9abc-5e420c768253",
  "kind": null,
  "count": 5,
  "url": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/CodeSystem/mii-cs-onko-mamma-her2neu-status-leitlinie",
  "concept": [ {
    "code": "positiv",
    "display": "HER2-positiv",
    "definition": "HER2-positiv: IHC 3+ (Score 3+) oder IHC 2+ (Score 2+) und ISH positiv"
  }, {
    "code": "low",
    "display": "HER2-low",
    "definition": "HER2-low: IHC 1+ oder IHC 2+ und ISH negativ"
  }, {
    "code": "ultralow",
    "display": "HER2-ultralow",
    "definition": "HER2-ultralow: IHC 0 mit Membranfärbung"
  }, {
    "code": "negativ",
    "display": "HER2-negativ",
    "definition": "HER2-negativ: IHC 0 ohne Membranfärbung"
  }, {
    "code": "equivocal",
    "display": "equivocal",
    "definition": "Equivocal: Grenzwertig/unklarer Befund, weitere Testung erforderlich"
  } ],
  "caseSensitive": true,
  "version": "2026.0.0-ballot",
  "contact": [ {
    "name": "Medizininformatik Initiative",
    "telecom": [ {
      "value": "https://www.medizininformatik-initiative.de/",
      "system": "url"
    } ]
  } ]
}