{
"description": "Basisiprofil zur Abbildung einer MII Bioprobe. Nicht zur direkten Implementierung gedacht, Module leiten bei Bedarf eigene Profile von diesem Profil ab.",
"_filename": "StructureDefinition-SpecimenCore.json",
"package_name": "de.medizininformatikinitiative.kerndatensatz.biobank",
"date": null,
"derivation": "constraint",
"publisher": null,
"fhirVersion": "4.0.1",
"name": "ProfileSpecimenBioprobeCore",
"abstract": false,
"type": "Specimen",
"experimental": null,
"resourceType": "StructureDefinition",
"title": "Profile - Specimen - Bioprobe - Core",
"package_version": "2025.0.0",
"status": "active",
"id": "f9c42b8b-955a-4571-a293-e29e6cb88a5c",
"kind": "resource",
"url": "https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/SpecimenCore",
"version": "2025.0.0-rc",
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"element": [ {
"id": "Specimen.identifier",
"path": "Specimen.identifier",
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"extension": [ {
"url": "http://hl7.org/fhir/StructureDefinition/translation",
"extension": [ {
"url": "lang",
"valueCode": "de-DE"
}, {
"url": "content",
"valueString": "Proben-ID"
} ]
}, {
"url": "http://hl7.org/fhir/StructureDefinition/translation",
"extension": [ {
"url": "lang",
"valueCode": "en-US"
}, {
"url": "content",
"valueString": "Specimen ID"
} ]
} ]
},
"_definition": {
"extension": [ {
"url": "http://hl7.org/fhir/StructureDefinition/translation",
"extension": [ {
"url": "lang",
"valueCode": "de-DE"
}, {
"url": "content",
"valueString": "Einrichtungsinterner Identifier der Probe."
} ]
}, {
"url": "http://hl7.org/fhir/StructureDefinition/translation",
"extension": [ {
"url": "lang",
"valueCode": "en-US"
}, {
"url": "content",
"valueString": "Internal identifier of the specimen at the institution."
} ]
} ]
},
"mustSupport": true
}, {
"id": "Specimen.status",
"min": 1,
"path": "Specimen.status",
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"extension": [ {
"url": "http://hl7.org/fhir/StructureDefinition/translation",
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}, {
"url": "content",
"valueString": "Verfügbarkeitsstatus"
} ]
}, {
"url": "http://hl7.org/fhir/StructureDefinition/translation",
"extension": [ {
"url": "lang",
"valueCode": "en-US"
}, {
"url": "content",
"valueString": "Availability status"
} ]
} ]
},
"_definition": {
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"url": "http://hl7.org/fhir/StructureDefinition/translation",
"extension": [ {
"url": "lang",
"valueCode": "de-DE"
}, {
"url": "content",
"valueString": "Der Status der Probe in Bezug auf die Verfügbarkeit für Forschung."
} ]
}, {
"url": "http://hl7.org/fhir/StructureDefinition/translation",
"extension": [ {
"url": "lang",
"valueCode": "en-US"
}, {
"url": "content",
"valueString": "The status of the specimen in terms of its availability for research."
} ]
} ]
},
"mustSupport": true
}, {
"id": "Specimen.type",
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"path": "Specimen.type",
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"url": "lang",
"valueCode": "de-DE"
}, {
"url": "content",
"valueString": "Probenart"
} ]
}, {
"url": "http://hl7.org/fhir/StructureDefinition/translation",
"extension": [ {
"url": "lang",
"valueCode": "en-US"
}, {
"url": "content",
"valueString": "Specimen type"
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} ]
},
"_definition": {
"extension": [ {
"url": "http://hl7.org/fhir/StructureDefinition/translation",
"extension": [ {
"url": "lang",
"valueCode": "de-DE"
}, {
"url": "content",
"valueString": "Die Art der Probe, codiert in SNOMED CT."
} ]
}, {
"url": "http://hl7.org/fhir/StructureDefinition/translation",
"extension": [ {
"url": "lang",
"valueCode": "en-US"
}, {
"url": "content",
"valueString": "The type of the specimen, encoded as SNOMED CT code."
} ]
} ]
},
"mustSupport": true
}, {
"id": "Specimen.type.coding",
"min": 1,
"path": "Specimen.type.coding",
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}
}, {
"id": "Specimen.type.coding:sct",
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"path": "Specimen.type.coding",
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},
"sliceName": "sct"
}, {
"id": "Specimen.type.coding:sct.system",
"path": "Specimen.type.coding.system",
"patternUri": "http://snomed.info/sct"
}, {
"id": "Specimen.subject",
"min": 1,
"path": "Specimen.subject",
"type": [ {
"code": "Reference",
"targetProfile": [ "http://hl7.org/fhir/StructureDefinition/Patient" ]
} ],
"_short": {
"extension": [ {
"url": "http://hl7.org/fhir/StructureDefinition/translation",
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"valueCode": "de-DE"
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"valueString": "Patient:in"
} ]
}, {
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"extension": [ {
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}, {
"url": "content",
"valueString": "Patient"
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} ]
},
"_definition": {
"extension": [ {
"url": "http://hl7.org/fhir/StructureDefinition/translation",
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"url": "lang",
"valueCode": "de-DE"
}, {
"url": "content",
"valueString": "Verweis auf die Person, von der die Probe stammt."
} ]
}, {
"url": "http://hl7.org/fhir/StructureDefinition/translation",
"extension": [ {
"url": "lang",
"valueCode": "en-US"
}, {
"url": "content",
"valueString": "Reference to the person from whom the specimen was collected."
} ]
} ]
},
"mustSupport": true
}, {
"id": "Specimen.parent",
"path": "Specimen.parent",
"_short": {
"extension": [ {
"url": "http://hl7.org/fhir/StructureDefinition/translation",
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"url": "lang",
"valueCode": "de-DE"
}, {
"url": "content",
"valueString": "Ist gewonnen aus"
} ]
}, {
"url": "http://hl7.org/fhir/StructureDefinition/translation",
"extension": [ {
"url": "lang",
"valueCode": "en-US"
}, {
"url": "content",
"valueString": "Derived from"
} ]
} ]
},
"_definition": {
"extension": [ {
"url": "http://hl7.org/fhir/StructureDefinition/translation",
"extension": [ {
"url": "lang",
"valueCode": "de-DE"
}, {
"url": "content",
"valueString": "Referenz auf eine übergeordnete Probe, aus der diese Probe gewonnen wurde."
} ]
}, {
"url": "http://hl7.org/fhir/StructureDefinition/translation",
"extension": [ {
"url": "lang",
"valueCode": "en-US"
}, {
"url": "content",
"valueString": "Reference to a parent specimen from which this specimen was derived."
} ]
} ]
},
"mustSupport": true
}, {
"id": "Specimen.request",
"path": "Specimen.request",
"_short": {
"extension": [ {
"url": "http://hl7.org/fhir/StructureDefinition/translation",
"extension": [ {
"url": "lang",
"valueCode": "de-DE"
}, {
"url": "content",
"valueString": "Entnahme-ID"
} ]
}, {
"url": "http://hl7.org/fhir/StructureDefinition/translation",
"extension": [ {
"url": "lang",
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}, {
"url": "content",
"valueString": "Collection ID"
} ]
} ]
},
"_definition": {
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"extension": [ {
"url": "lang",
"valueCode": "de-DE"
}, {
"url": "content",
"valueString": "Der Identifier der Probenentnahme."
} ]
}, {
"url": "http://hl7.org/fhir/StructureDefinition/translation",
"extension": [ {
"url": "lang",
"valueCode": "en-US"
}, {
"url": "content",
"valueString": "The identifier for the specimen collection."
} ]
} ]
},
"mustSupport": true
}, {
"id": "Specimen.collection",
"min": 1,
"path": "Specimen.collection",
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"extension": [ {
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"extension": [ {
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"valueCode": "de-DE"
}, {
"url": "content",
"valueString": "Probenentnahme"
} ]
}, {
"url": "http://hl7.org/fhir/StructureDefinition/translation",
"extension": [ {
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"valueCode": "en-US"
}, {
"url": "content",
"valueString": "Specimen sampling"
} ]
} ]
},
"_definition": {
"extension": [ {
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"extension": [ {
"url": "lang",
"valueCode": "de-DE"
}, {
"url": "content",
"valueString": "Informationen über den Prozess der Probenentnahme, einschließlich Entnahmezeitpunkt und -stelle."
} ]
}, {
"url": "http://hl7.org/fhir/StructureDefinition/translation",
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"url": "lang",
"valueCode": "en-US"
}, {
"url": "content",
"valueString": "Information about the specimen collection process, including collection time and site."
} ]
} ]
},
"mustSupport": true
}, {
"id": "Specimen.collection.extension",
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"rules": "open",
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"discriminator": [ {
"path": "url",
"type": "value"
} ]
}
}, {
"id": "Specimen.collection.extension:einstellungBlutversorgung",
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"path": "Specimen.collection.extension",
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"code": "Extension",
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} ],
"sliceName": "einstellungBlutversorgung",
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}, {
"id": "Specimen.collection.collected[x]",
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"extension": [ {
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"valueCode": "de-DE"
}, {
"url": "content",
"valueString": "Entnahmezeitpunkt"
} ]
}, {
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"extension": [ {
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"valueCode": "en-US"
}, {
"url": "content",
"valueString": "Sampling time"
} ]
} ]
},
"_definition": {
"extension": [ {
"url": "http://hl7.org/fhir/StructureDefinition/translation",
"extension": [ {
"url": "lang",
"valueCode": "de-DE"
}, {
"url": "content",
"valueString": "Der Zeitpunkt, zu dem die Probe entnommen oder gesammelt wurde."
} ]
}, {
"url": "http://hl7.org/fhir/StructureDefinition/translation",
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"url": "lang",
"valueCode": "en-US"
}, {
"url": "content",
"valueString": "The time when the specimen was collected or obtained."
} ]
} ]
},
"mustSupport": true
}, {
"id": "Specimen.collection.bodySite",
"path": "Specimen.collection.bodySite",
"_short": {
"extension": [ {
"url": "http://hl7.org/fhir/StructureDefinition/translation",
"extension": [ {
"url": "lang",
"valueCode": "de-DE"
}, {
"url": "content",
"valueString": "Anatomische Lokalisation"
} ]
}, {
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"valueCode": "en-US"
}, {
"url": "content",
"valueString": "anatomical localisation"
} ]
} ]
},
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"human": "Bei der Angabe der Entnahmestelle muss ein ICD-O-3 Topographiecode oder ein SNOMED CT Code angegeben werden.",
"source": "https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/SpecimenCore",
"severity": "error",
"expression": "coding.where(system = 'http://snomed.info/sct' or system = 'http://terminology.hl7.org/CodeSystem/icd-o-3').exists()"
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"_definition": {
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}, {
"url": "content",
"valueString": "Die Körperstelle, von der die Probe entnommen wurde gemäß icd-o-3."
} ]
}, {
"url": "http://hl7.org/fhir/StructureDefinition/translation",
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"url": "lang",
"valueCode": "en-US"
}, {
"url": "content",
"valueString": "The body site from which the specimen was collected according to icd-o-3."
} ]
} ]
},
"mustSupport": true
}, {
"id": "Specimen.collection.bodySite.coding",
"path": "Specimen.collection.bodySite.coding",
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"type": "pattern"
} ]
}
}, {
"id": "Specimen.collection.bodySite.coding:sct",
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"min": 0,
"path": "Specimen.collection.bodySite.coding",
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"valueSet": "https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/ValueSet/sct-body-structures"
},
"sliceName": "sct",
"mustSupport": true
}, {
"id": "Specimen.collection.bodySite.coding:sct.system",
"path": "Specimen.collection.bodySite.coding.system",
"patternUri": "http://snomed.info/sct"
}, {
"id": "Specimen.collection.bodySite.coding:icd-o-3",
"max": "1",
"min": 0,
"path": "Specimen.collection.bodySite.coding",
"binding": {
"strength": "required",
"valueSet": "https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/ValueSet/icd-o-3-topography"
},
"sliceName": "icd-o-3",
"mustSupport": true
}, {
"id": "Specimen.collection.bodySite.coding:icd-o-3.system",
"path": "Specimen.collection.bodySite.coding.system",
"patternUri": "http://terminology.hl7.org/CodeSystem/icd-o-3"
}, {
"id": "Specimen.collection.fastingStatus[x]",
"path": "Specimen.collection.fastingStatus[x]",
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"extension": [ {
"url": "http://hl7.org/fhir/StructureDefinition/translation",
"extension": [ {
"url": "lang",
"valueCode": "de-DE"
}, {
"url": "content",
"valueString": "Nüchternstatus"
} ]
}, {
"url": "http://hl7.org/fhir/StructureDefinition/translation",
"extension": [ {
"url": "lang",
"valueCode": "en-US"
}, {
"url": "content",
"valueString": "Fasting status"
} ]
} ]
},
"slicing": {
"rules": "open",
"ordered": false,
"discriminator": [ {
"path": "$this",
"type": "type"
} ]
},
"_definition": {
"extension": [ {
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"extension": [ {
"url": "lang",
"valueCode": "de-DE"
}, {
"url": "content",
"valueString": "Der Nüchternstatus der Person zum Zeitpunkt der Probenentnahme."
} ]
}, {
"url": "http://hl7.org/fhir/StructureDefinition/translation",
"extension": [ {
"url": "lang",
"valueCode": "en-US"
}, {
"url": "content",
"valueString": "The fasting status of the person at the time the specimen was collected."
} ]
} ]
},
"mustSupport": true
}, {
"id": "Specimen.collection.fastingStatus[x]:fastingStatusCodeableConcept",
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"min": 0,
"path": "Specimen.collection.fastingStatus[x]",
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"binding": {
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"valueSet": "http://terminology.hl7.org/ValueSet/v2-0916"
},
"sliceName": "fastingStatusCodeableConcept"
}, {
"id": "Specimen.processing",
"path": "Specimen.processing",
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"extension": [ {
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"valueCode": "de-DE"
}, {
"url": "content",
"valueString": "Probenverarbeitung"
} ]
}, {
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}, {
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} ]
},
"slicing": {
"rules": "open",
"discriminator": [ {
"path": "$this.procedure.coding",
"type": "pattern"
} ]
},
"_definition": {
"extension": [ {
"url": "http://hl7.org/fhir/StructureDefinition/translation",
"extension": [ {
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"valueCode": "de-DE"
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"url": "content",
"valueString": "Details zur Verarbeitung der Probe, einschließlich Prozeduren und Verarbeitungszeitraum."
} ]
}, {
"url": "http://hl7.org/fhir/StructureDefinition/translation",
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"url": "content",
"valueString": "Details about the processing of the specimen, including procedures and processing period."
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} ]
},
"mustSupport": true
}, {
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"path": "Specimen.processing.extension",
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}
}, {
"id": "Specimen.processing.extension:temperaturbedingungen",
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"min": 1,
"path": "Specimen.processing.extension",
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} ],
"sliceName": "temperaturbedingungen",
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}, {
"id": "Specimen.processing.procedure",
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"path": "Specimen.processing.procedure",
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}, {
"url": "http://hl7.org/fhir/StructureDefinition/translation",
"extension": [ {
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}, {
"url": "content",
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} ]
},
"binding": {
"strength": "example",
"valueSet": "https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/ValueSet/sct-lab-procedure"
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"_definition": {
"extension": [ {
"url": "http://hl7.org/fhir/StructureDefinition/translation",
"extension": [ {
"url": "lang",
"valueCode": "de-DE"
}, {
"url": "content",
"valueString": "Die angewendete Prozedur zur Verarbeitung der Probe, z.B. Zentrifugation."
} ]
}, {
"url": "http://hl7.org/fhir/StructureDefinition/translation",
"extension": [ {
"url": "lang",
"valueCode": "en-US"
}, {
"url": "content",
"valueString": "The procedure applied to process the specimen, e.g. centrifugation."
} ]
} ]
},
"mustSupport": true
}, {
"id": "Specimen.processing.procedure.coding",
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"path": "Specimen.processing.procedure.coding",
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}
}, {
"id": "Specimen.processing.procedure.coding:sct",
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"min": 1,
"path": "Specimen.processing.procedure.coding",
"sliceName": "sct",
"mustSupport": true
}, {
"id": "Specimen.processing.procedure.coding:sct.system",
"path": "Specimen.processing.procedure.coding.system",
"patternUri": "http://snomed.info/sct"
}, {
"id": "Specimen.processing.additive",
"path": "Specimen.processing.additive",
"type": [ {
"code": "Reference",
"targetProfile": [ "https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Substance" ]
} ],
"_short": {
"extension": [ {
"url": "http://hl7.org/fhir/StructureDefinition/translation",
"extension": [ {
"url": "lang",
"valueCode": "de-DE"
}, {
"url": "content",
"valueString": "Additive bei Verarbeitung"
} ]
}, {
"url": "http://hl7.org/fhir/StructureDefinition/translation",
"extension": [ {
"url": "lang",
"valueCode": "en-US"
}, {
"url": "content",
"valueString": "Processing additives"
} ]
} ]
},
"_definition": {
"extension": [ {
"url": "http://hl7.org/fhir/StructureDefinition/translation",
"extension": [ {
"url": "lang",
"valueCode": "de-DE"
}, {
"url": "content",
"valueString": "Zusatzstoffe, die während der Probenverarbeitung verwendet wurden, z.B. Fixierungsmittel."
} ]
}, {
"url": "http://hl7.org/fhir/StructureDefinition/translation",
"extension": [ {
"url": "lang",
"valueCode": "en-US"
}, {
"url": "content",
"valueString": "Additives used during the specimen processing, e.g. fixatives."
} ]
} ]
},
"mustSupport": true
}, {
"id": "Specimen.processing.time[x]",
"path": "Specimen.processing.time[x]",
"slicing": {
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"discriminator": [ {
"path": "$this",
"type": "type"
} ]
},
"mustSupport": true
}, {
"path": "Specimen.processing.time[x]",
"min": 0,
"_definition": {
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}, {
"url": "content",
"valueString": "Der Zeitraum, in dem die Probe verarbeitet wurde."
} ]
}, {
"url": "http://hl7.org/fhir/StructureDefinition/translation",
"extension": [ {
"url": "lang",
"valueCode": "en-US"
}, {
"url": "content",
"valueString": "The time period during which the specimen was processed."
} ]
} ]
},
"type": [ {
"code": "Period"
} ],
"mustSupport": true,
"_short": {
"extension": [ {
"url": "http://hl7.org/fhir/StructureDefinition/translation",
"extension": [ {
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"valueCode": "de-DE"
}, {
"url": "content",
"valueString": "Verarbeitungszeitraum"
} ]
}, {
"url": "http://hl7.org/fhir/StructureDefinition/translation",
"extension": [ {
"url": "lang",
"valueCode": "en-US"
}, {
"url": "content",
"valueString": "Processing period"
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