description: 此基因資訊-Observation Diagnostic TWPAS Profile說明本IG如何進一步定義FHIR的Observation Resource以呈現癌藥事前審查之基因資訊
package_name: tw.gov.mohw.nhi.pas
derivation: constraint
name: ObservationDiagnosticTWPAS
type: Observation
elements:
  category:
    short: 因FHIR設計而需必填
    index: 2
    elements:
      coding:
        index: 3
        elements:
          system:
            pattern: {type: Uri, value: 'https://nhicore.nhi.gov.tw/pas/CodeSystem/nhi-supporting-info-type'}
            index: 4
          code:
            pattern: {type: Code, value: geneInfo}
            index: 5
    required: [coding]
  meta:
    index: 0
    elements:
      profile:
        pattern: {type: Canonical, value: 'https://nhicore.nhi.gov.tw/pas/StructureDefinition/Observation-diagnostic-twpas'}
        index: 1
    required: [profile]
  derivedFrom:
    type: Reference
    short: 基因報告
    mustSupport: true
    refers: ['https://nhicore.nhi.gov.tw/pas/StructureDefinition/DocumentReference-twpas']
    index: 20
  interpretation: {short: 基因臨床判讀結果，醫師判讀結果。請勿將醫事機構名稱、病人及醫師姓名等資訊列入結果中上傳，且不得包含HTML或XML等語法。, mustSupport: true, index: 17}
  method:
    short: 基因檢測方法
    binding: {strength: extensible, valueSet: 'http://loinc.org/vs/LL4048-6'}
    mustSupport: true
    index: 18
  specimen:
    type: Reference
    short: 基因檢測檢體類型
    mustSupport: true
    refers: ['https://nhicore.nhi.gov.tw/pas/StructureDefinition/Specimen-twpas']
    index: 19
  value:
    short: 基因檢測分析結果。請勿將醫事機構名稱、病人及醫師姓名等資訊列入結果中上傳，且不得包含HTML或XML等語法。
    mustSupport: true
    choices: [valueString]
    index: 15
  valueString: {type: string, short: 基因檢測分析結果。請勿將醫事機構名稱、病人及醫師姓名等資訊列入結果中上傳，且不得包含HTML或XML等語法。, mustSupport: true, choiceOf: value, index: 16}
  component:
    index: 21
    slicing:
      rules: closed
      discriminator:
      - {path: code.coding.system, type: pattern}
      min: 1
      slices:
        gene-test-code:
          match:
            code:
              coding: {system: 'http://loinc.org'}
          schema:
            short: 基因檢測代碼
            mustSupport: true
            array: true
            min: 1
            _required: true
            index: 22
            elements:
              code:
                short: 基因檢測代碼
                binding: {strength: extensible, valueSet: 'https://nhicore.nhi.gov.tw/pas/ValueSet/gene-test-code'}
                mustSupport: true
                index: 23
                elements:
                  coding:
                    index: 24
                    elements:
                      system:
                        pattern: {type: Uri, value: 'http://loinc.org'}
                        index: 25
                    required: [system]
                required: [coding]
              value:
                short: 基因檢測實際結果
                mustSupport: true
                choices: []
                index: 27
              interpretation:
                short: 基因突變類型
                binding: {strength: extensible, valueSet: 'https://nhicore.nhi.gov.tw/pas/ValueSet/dna-change-type'}
                constraint:
                  pas-1: {human: text、coding至少需存在一個。, source: 'https://nhicore.nhi.gov.tw/pas/StructureDefinition/Observation-diagnostic-twpas', severity: error, expression: text.exists() or coding.exists()}
                mustSupport: true
                index: 28
                elements:
                  coding:
                    index: 29
                    elements:
                      code: {short: 'LA6692-3: Deletion | LA6686-5: Duplication | LA6687-3: Insertion | LA6688-1: Insertion/Deletion | LA6689-9: Inversion | LA6690-7: Substitution | 101397-8: Copy number variation analysis Sequencing Doc (Bld/Tiss) | 81695-9: MSI Ca spec-Imp | 94077-5: TMB Tumor-Imp | O55-2: Delins', index: 30}
                    required: [code]
                  text: {short: 基因突變類型。若無合適代碼，可使用此欄位以文字呈現。請勿將醫事機構名稱、病人及醫師姓名等資訊列入結果中上傳，且不得包含HTML或XML等語法。, index: 31}
            required: [value]
  effectiveDateTime: {type: dateTime, short: 基因檢測日期, mustSupport: true, choiceOf: effective, index: 12}
  effective:
    short: 基因檢測日期
    mustSupport: true
    choices: [effectiveDateTime]
    index: 11
  code:
    elements:
      coding:
        index: 6
        elements:
          system:
            pattern: {type: Uri, value: 'http://loinc.org'}
            index: 7
          code:
            mustSupport: true
            pattern: {type: Code, value: 69548-6}
            index: 8
        required: [code]
    required: [coding]
  subject:
    type: Reference
    mustSupport: true
    refers: ['https://nhicore.nhi.gov.tw/pas/StructureDefinition/Patient-twpas']
    index: 9
  performer:
    type: Reference
    short: 基因檢測機構，衛福部公告名冊或LDTs核定函上之「案件編號」。
    mustSupport: true
    refers: ['https://nhicore.nhi.gov.tw/pas/StructureDefinition/Organization-genetic-testing-twpas']
    index: 13
package_version: 1.0.9
class: profile
kind: resource
url: https://nhicore.nhi.gov.tw/pas/StructureDefinition/Observation-diagnostic-twpas
base: http://hl7.org/fhir/StructureDefinition/Observation
version: 1.0.9
required: [effectiveDateTime, valueString, method, component, value, subject, specimen, meta, category, effective, performer]