{
"description": "Representing the Substances in the Norwegian Substance database",
"_filename": "SubstanceSpecificationNoma2.0.1.StructureDefinition.json",
"package_name": "noma.fhir.mpd",
"date": null,
"derivation": "constraint",
"publisher": null,
"fhirVersion": "4.0.1",
"name": "SubstanceSpecificationNOMA",
"abstract": false,
"type": "SubstanceSpecification",
"experimental": null,
"resourceType": "StructureDefinition",
"title": null,
"package_version": "2.0.0",
"status": "active",
"id": "f60cfb81-c5f5-42f1-b09b-2c45503ef7c6",
"kind": "resource",
"url": "https://example.org/fhir/StructureDefinition/2.0.0/SubstanceSpecificationNOMA",
"version": "2.0.0",
"differential": {
"element": [ {
"id": "SubstanceSpecification",
"path": "SubstanceSpecification",
"alias": [ "SubstanceDefinition (FHIR R5)" ],
"comment": "Based on ISO 11238"
}, {
"id": "SubstanceSpecification.identifier",
"min": 1,
"path": "SubstanceSpecification.identifier",
"short": "Indentifier for the substance.",
"definition": "Identifier by which this substance is known, specific to NoMA's FHIR API\r\nUrl (preliminary): http://legemiddelverket.no/fhir/SAFEST/SafestSubstanceDefinitionID \r\nAlternative (business) identifiers - SMS ID, UniiCode and FEST ID - are provided in the extension. since the identifier attribute can provide at most one identifier."
}, {
"id": "SubstanceSpecification.identifier.system",
"path": "SubstanceSpecification.identifier.system",
"fixedUri": "http://legemiddelverket.no/fhir/SAFEST/SafestSubstanceDefinitionID",
"definition": "The namespace is preliminary and will be replaced with a stable \"GUPRI\""
}, {
"id": "SubstanceSpecification.type",
"path": "SubstanceSpecification.type",
"alias": [ "category" ],
"short": "High level categorization, e.g. chemical, polymer or nucleic acid",
"binding": {
"strength": "example",
"valueSet": "https://spor.ema.europa.eu/rmswi/#/lists/100000075826/terms",
"description": "SPOR RMS Substance Types"
},
"definition": "High level categorization, e.g. chemical, polymer or nucleic acid."
}, {
"id": "SubstanceSpecification.type.coding.system",
"path": "SubstanceSpecification.type.coding.system",
"fixedUri": "https://api.legemiddelverket.no/FHIR-R4/CodeSystem/905de22c-b0f9-4ad5-bfcb-08e1d6fef20d",
"definition": "The identification of the code system that defines the meaning of the symbol in the code.\r\nThe system URL is preliminary and will be replaced with a stable \"GUPRI\""
}, {
"id": "SubstanceSpecification.status",
"max": "0",
"path": "SubstanceSpecification.status"
}, {
"id": "SubstanceSpecification.domain",
"max": "0",
"path": "SubstanceSpecification.domain"
}, {
"id": "SubstanceSpecification.description",
"max": "0",
"path": "SubstanceSpecification.description"
}, {
"id": "SubstanceSpecification.source",
"max": "0",
"path": "SubstanceSpecification.source"
}, {
"id": "SubstanceSpecification.comment",
"max": "0",
"path": "SubstanceSpecification.comment"
}, {
"id": "SubstanceSpecification.moiety",
"max": "0",
"path": "SubstanceSpecification.moiety"
}, {
"id": "SubstanceSpecification.property",
"max": "0",
"path": "SubstanceSpecification.property"
}, {
"id": "SubstanceSpecification.referenceInformation",
"max": "0",
"path": "SubstanceSpecification.referenceInformation"
}, {
"id": "SubstanceSpecification.structure",
"max": "0",
"path": "SubstanceSpecification.structure"
}, {
"id": "SubstanceSpecification.code",
"max": "0",
"path": "SubstanceSpecification.code"
}, {
"id": "SubstanceSpecification.name",
"path": "SubstanceSpecification.name",
"definition": "Names applicable to this substance.. Provided in Norwegian, English and (if exists) Latin"
}, {
"id": "SubstanceSpecification.name.extension",
"path": "SubstanceSpecification.name.extension",
"alias": [ "alias" ]
}, {
"id": "SubstanceSpecification.name.extension:alias",
"path": "SubstanceSpecification.name.extension",
"type": [ {
"code": "Extension",
"profile": [ "https://example.org/fhir/StructureDefinition/SubstanceSpecificationNameAliasNOMA" ]
} ],
"sliceName": "alias",
"isModifier": false
}, {
"id": "SubstanceSpecification.name.language",
"path": "SubstanceSpecification.name.language",
"definition": "Language of the name. Norwegian, English or (if exists) Latin"
}, {
"id": "SubstanceSpecification.molecularWeight",
"max": "0",
"path": "SubstanceSpecification.molecularWeight"
}, {
"id": "SubstanceSpecification.relationship.relationship",
"path": "SubstanceSpecification.relationship.relationship",
"alias": [ "type" ]
}, {
"id": "SubstanceSpecification.relationship.amount[x]",
"max": "0",
"path": "SubstanceSpecification.relationship.amount[x]",
"slicing": {
"rules": "open",
"discriminator": [ {
"path": "$this",
"type": "type"
} ]
}
}, {
"id": "SubstanceSpecification.relationship.amount[x]:amountQuantity",
"max": "0",
"path": "SubstanceSpecification.relationship.amount[x]",
"type": [ {
"code": "Quantity"
} ],
"sliceName": "amountQuantity"
}, {
"id": "SubstanceSpecification.relationship.amount[x]:amountRange",
"max": "0",
"path": "SubstanceSpecification.relationship.amount[x]",
"type": [ {
"code": "Range"
} ],
"sliceName": "amountRange"
}, {
"id": "SubstanceSpecification.relationship.amount[x]:amountRatio",
"max": "0",
"path": "SubstanceSpecification.relationship.amount[x]",
"type": [ {
"code": "Ratio"
} ],
"sliceName": "amountRatio"
}, {
"id": "SubstanceSpecification.relationship.amount[x]:amountString",
"max": "0",
"path": "SubstanceSpecification.relationship.amount[x]",
"type": [ {
"code": "string"
} ],
"sliceName": "amountString"
}, {
"id": "SubstanceSpecification.nucleicAcid",
"max": "0",
"path": "SubstanceSpecification.nucleicAcid"
}, {
"id": "SubstanceSpecification.polymer",
"max": "0",
"path": "SubstanceSpecification.polymer"
}, {
"id": "SubstanceSpecification.protein",
"max": "0",
"path": "SubstanceSpecification.protein"
}, {
"id": "SubstanceSpecification.sourceMaterial",
"max": "0",
"path": "SubstanceSpecification.sourceMaterial"
}, {
"id": "SubstanceSpecification.extension",
"min": 1,
"path": "SubstanceSpecification.extension",
"type": [ {
"code": "Extension"
} ],
"slicing": {
"rules": "open",
"ordered": true,
"discriminator": [ {
"path": "url",
"type": "value"
} ]
},
"isModifier": false,
"mustSupport": false
}, {
"path": "SubstanceSpecification.extension",
"requirements": "Provides ability to map substances between different substance master data systems",
"definition": "The substance ID in the [EMA SPOR substances management services](https://spor.ema.europa.eu/smswi/#/). \r\nIdentifies substnaces in EU marketing authorisations.",
"isModifier": false,
"short": "SPOR SMS ID",
"type": [ {
"code": "Extension",
"profile": [ "http://legemiddelverket.no/fhir/StructureDefinition/IdentifierExtension" ]
} ],
"sliceName": "SMSID",
"meaningWhenMissing": "SPOR does not contain the relevant substance",
"id": "SubstanceSpecification.extension:SMSID",
"comment": "URL (preliminary): http://legemiddelverket.no/fhir/SAFEST/SMSID"
}, {
"path": "SubstanceSpecification.extension",
"requirements": "Provides ability to map substances between different susbtance master data systems",
"definition": "The Unique Ingredient Identifier (UNII) generated by the [Global Substance Registration System (GSRS)](https://gsrs.ncats.nih.gov/) of the US Food and Drug Administration.",
"isModifier": false,
"short": "GSRS Substance ID",
"type": [ {
"code": "Extension",
"profile": [ "http://legemiddelverket.no/fhir/StructureDefinition/IdentifierExtension" ]
} ],
"sliceName": "UniiCode",
"meaningWhenMissing": "GSRS does not contain the relevant substance",
"id": "SubstanceSpecification.extension:UniiCode",
"comment": "URL (preliminary): http://legemiddelverket.no/fhir/SAFEST/UniiCode"
}, {
"path": "SubstanceSpecification.extension",
"min": 1,
"definition": "The substance ID in the [FEST medicinal product master data](https://www.dmp.no/om-oss/distribusjon-av-legemiddeldata/fest)",
"isModifier": false,
"short": "FEST substance ID",
"type": [ {
"code": "Extension",
"profile": [ "http://legemiddelverket.no/fhir/StructureDefinition/IdentifierExtension" ]
} ],
"sliceName": "FestId",
"id": "SubstanceSpecification.extension:FestId",
"comment": "URL (preliminary): http://legemiddelverket.no/FEST/SubstansID"
}, {
"id": "SubstanceSpecification.extension:classification",
"path": "SubstanceSpecification.extension",
"type": [ {
"code": "Extension",
"profile": [ "http://legemiddelverket.no/fhir/StructureDefinition/substancespecification-classification" ]
} ],
"short": "Classifies the substance",
"comment": "##### Published (optional) classification categories:\r\n\r\n###### **E-Number**\r\nThe substance's [E-number(s)](https://ec.europa.eu/food/food-feed-portal/screen/food-additives/search). A substance can have multiple e-numbers.\r\nCardinality: 0..* \r\nCode: The E-number \r\nDisplay: The E-number name (substance) \r\nUrl (preliminary): https://simplifier.net/safest/e-number\r\n###### **Is Therapeutic**\r\nWhether the substance is therapeutic (only published when \"true\"). \r\nCardinality: 0..1 \r\nCode: \"true\" \r\nDisplay: \"Er terapautisk del\" \r\nUrl (preliminary): https://simplifier.net/safest/activemoiety\r\n###### **Is Prodrug**\r\nWhether the substance is a prodrug (only published when \"true\") \r\nCardinality: 0..1 \r\nCode: \"true\" \r\nDisplay: \"Er prodrug\" \r\nUrl (preliminary): ttps://simplifier.net/safest/prodrug\r\n###### **Is Complex**\r\nWhether the substance is complex (only published when \"true\") \r\nCardinality: 0..1 \r\nCode: \"true\" \r\nDisplay: \"Er kompleks\" \r\nUrl (preliminary): https://simplifier.net/safest/complex \r\n###### **ATC codes**\r\nAll the substance's ATC code(s). Human codes only.\r\nCardinality: 0..* \r\nCode: The ATC code \r\nDisplay: The (substance) name \r\nUrls (preliminary), one per first-level ATC: \r\n\r\n| First-level ATC category | Url |\r\n| :------- | :------ |\r\n| Alimentary tract and metabolism | https://api.legemiddelverket.no/FHIR-R4/CodeSystem/dcedfe5f-d7dd-43f4-a351-8744395249dd |\r\n| Blood and blood forming organs | https://api.legemiddelverket.no/FHIR-R4/CodeSystem/127f5448-fa44-4da4-9589-438749da0158 |\r\n| Cardiovascular system | https://api.legemiddelverket.no/FHIR-R4/CodeSystem/e104a7eb-e832-4d57-946d-d402b71ecc22 |\r\n| Dermatologicals | https://api.legemiddelverket.no/FHIR-R4/CodeSystem/f5a60497-f1c5-4163-ad34-a3c614d2f6b4 |\r\n| Genito urinary system and sex hormones | https://api.legemiddelverket.no/FHIR-R4/CodeSystem/1fd6dad4-6b05-44ee-9a61-9409927bf195 |\r\n| Systemic hormonal preparations, excl. sex hormones and insulins | https://api.legemiddelverket.no/FHIR-R4/CodeSystem/bd343711-ab45-4ebd-9f2c-b128f422645e |\r\n| Antiinfectives for systemic use | https://api.legemiddelverket.no/FHIR-R4/CodeSystem/e9f15a26-d384-48c2-a74d-3fa95f44a9dc |\r\n| Antineoplastic and immunomodulating agents | https://api.legemiddelverket.no/FHIR-R4/CodeSystem/849bc27b-a66d-49ad-9389-d8f19d63b480 |\r\n| Musculo-skeletal system | https://api.legemiddelverket.no/FHIR-R4/CodeSystem/82311936-f7e3-4c24-8821-229f055f7c64 |\r\n| Nervous system | https://api.legemiddelverket.no/FHIR-R4/CodeSystem/f7949a93-d26e-4235-ac5d-d2b898a7aad4 |\r\n| Antiparasitic products, insecticides and repellents | https://api.legemiddelverket.no/FHIR-R4/CodeSystem/a9a04ea3-c412-4c27-b191-fddb4ae4d162 |\r\n| Respiratory system | https://api.legemiddelverket.no/FHIR-R4/CodeSystem/451f509c-f18b-48e1-ac75-d1852b846eee |\r\n| Sensory organs | https://api.legemiddelverket.no/FHIR-R4/CodeSystem/2949f36e-6b6f-496a-96c8-c61429e75797 |\r\n| Various | https://api.legemiddelverket.no/FHIR-R4/CodeSystem/e5390228-1602-4bef-8ca9-fca1771de4d1 |",
"sliceName": "classification",
"definition": "Optional xtension for classifying substances.",
"isModifier": false
} ]
},
"baseDefinition": "http://hl7.org/fhir/StructureDefinition/SubstanceSpecification"
}