description: Beschreibt die Neigung zu Mutationen aufgrund einer gestörten Fehlpaarungsreparatur (DNA mismatch repair, MMR).
package_name: de.medizininformatikinitiative.kerndatensatz.mtb
derivation: constraint
name: MII_PR_MTB_Mikrosatelliteninstabilitaet
type: Observation
elements:
  category: {mustSupport: true, index: 1}
  interpretation:
    binding: {strength: required, valueSet: 'https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/ValueSet/mii-vs-mtb-msi'}
    mustSupport: true
    index: 8
  encounter: {mustSupport: true, index: 4}
  method:
    short: IHC|PCR|bioinformatic
    binding: {strength: preferred, valueSet: 'https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/ValueSet/mii-vs-mtb-msi-method-type'}
    mustSupport: true
    index: 9
  specimen: {mustSupport: true, index: 10}
  valueQuantity: {type: Quantity, mustSupport: true, choiceOf: value, index: 7}
  value:
    mustSupport: true
    choices: [valueQuantity]
    index: 6
  status: {mustSupport: true, index: 0}
  code: {mustSupport: true, index: 2}
  subject:
    type: Reference
    mustSupport: true
    refers: ['http://hl7.org/fhir/StructureDefinition/Group', 'http://hl7.org/fhir/StructureDefinition/Patient']
    index: 3
package_version: 2025.0.0-ballot
class: profile
kind: resource
url: https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-pr-mtb-mikrosatelliteninstabilitaet
base: https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-pr-mtb-molekularer-biomarker
version: 2024.0.0-ballot
required: [subject]