description: RNA-Fusion
package_name: rs/de.medizininformatikinitiative.kerndatensatz.mtb
derivation: constraint
name: MII_PR_MTB_RNA_Fusion
type: Observation
elements:
  meta:
    mustSupport: true
    index: 0
    elements:
      profile: {mustSupport: true, index: 1}
  identifier: {short: VariantenId innerhalb des NGS-Befundes, mustSupport: true, index: 2}
  focus:
    type: Reference
    mustSupport: true
    refers: ['https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-pr-mtb-diagnose-primaertumor', 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-diagnose-primaertumor']
    index: 3
  component:
    array: true
    min: 12
    index: 4
    slicing:
      slices:
        three-prime-transcript-id:
          match: {}
          schema:
            short: 3' Transcript - Identifier
            mustSupport: true
            _required: true
            index: 55
            elements:
              code: {mustSupport: true, index: 56}
              value:
                choices: []
                index: 58
                slicing:
                  rules: open
                  ordered: false
                  discriminator:
                  - {path: $this, type: type}
                  min: null
                  slices:
                    valueCodeableConcept:
                      match: {}
                      schema:
                        mustSupport: true
                        choices: [valueCodeableConcept]
                        index: 60
                      min: 0
                      max: 1
              valueCodeableConcept:
                type: CodeableConcept
                mustSupport: true
                choiceOf: value
                index: 61
                slicing:
                  slices:
                    valueCodeableConcept:
                      match: {}
                      schema: {type: CodeableConcept, mustSupport: true, choiceOf: value, index: 61}
                      min: 0
                      max: 1
        allelic-read-depth:
          match: {}
          schema:
            short: Number reported reads
            index: 5
            elements:
              code: {mustSupport: true, index: 6}
              value:
                mustSupport: true
                choices: []
                index: 8
        three-prime-gene:
          match: {}
          schema:
            short: 3' Domain - Gene
            mustSupport: true
            _required: true
            index: 48
            elements:
              code: {mustSupport: true, index: 49}
              value:
                choices: []
                index: 51
                slicing:
                  rules: open
                  ordered: false
                  discriminator:
                  - {path: $this, type: type}
                  min: null
                  slices:
                    valueCodeableConcept:
                      match: {}
                      schema:
                        mustSupport: true
                        choices: [valueCodeableConcept]
                        index: 53
                      min: 0
                      max: 1
              valueCodeableConcept:
                type: CodeableConcept
                mustSupport: true
                choiceOf: value
                index: 54
                slicing:
                  slices:
                    valueCodeableConcept:
                      match: {}
                      schema: {type: CodeableConcept, mustSupport: true, choiceOf: value, index: 54}
                      min: 0
                      max: 1
        five-prime-transcript-id:
          match: {}
          schema:
            short: 5' Transcript - Identifier
            mustSupport: true
            _required: true
            index: 30
            elements:
              code: {mustSupport: true, index: 31}
              value:
                choices: []
                index: 33
                slicing:
                  rules: open
                  ordered: false
                  discriminator:
                  - {path: $this, type: type}
                  min: null
                  slices:
                    valueCodeableConcept:
                      match: {}
                      schema:
                        mustSupport: true
                        choices: [valueCodeableConcept]
                        index: 35
                      min: 0
                      max: 1
              valueCodeableConcept:
                type: CodeableConcept
                mustSupport: true
                choiceOf: value
                index: 36
                slicing:
                  slices:
                    valueCodeableConcept:
                      match: {}
                      schema: {type: CodeableConcept, mustSupport: true, choiceOf: value, index: 36}
                      min: 0
                      max: 1
        five-prime-strand:
          match: {}
          schema:
            short: 5' Strand
            mustSupport: true
            _required: true
            index: 46
            elements:
              code: {mustSupport: true, index: 47}
        five-prime-gene:
          match: {}
          schema:
            short: 5' Domain - Gene
            mustSupport: true
            _required: true
            index: 23
            elements:
              code: {mustSupport: true, index: 24}
              value:
                choices: []
                index: 26
                slicing:
                  rules: open
                  ordered: false
                  discriminator:
                  - {path: $this, type: type}
                  min: null
                  slices:
                    valueCodeableConcept:
                      match: {}
                      schema:
                        mustSupport: true
                        choices: [valueCodeableConcept]
                        index: 28
                      min: 0
                      max: 1
              valueCodeableConcept:
                type: CodeableConcept
                mustSupport: true
                choiceOf: value
                index: 29
                slicing:
                  slices:
                    valueCodeableConcept:
                      match: {}
                      schema: {type: CodeableConcept, mustSupport: true, choiceOf: value, index: 29}
                      min: 0
                      max: 1
        five-prime-position:
          match: {}
          schema:
            short: 5' Domain - Position
            mustSupport: true
            _required: true
            index: 44
            elements:
              code: {mustSupport: true, index: 45}
        three-prime-strand:
          match: {}
          schema:
            short: 3' Strand
            mustSupport: true
            _required: true
            index: 71
            elements:
              code: {mustSupport: true, index: 72}
        three-prime-position:
          match: {}
          schema:
            short: 3' Domain - Position
            mustSupport: true
            _required: true
            index: 69
            elements:
              code: {mustSupport: true, index: 70}
        five-prime-exon-id:
          match: {}
          schema:
            short: 5' Exon - Identifier
            mustSupport: true
            _required: true
            index: 37
            elements:
              code: {mustSupport: true, index: 38}
              value:
                choices: []
                index: 40
                slicing:
                  rules: open
                  ordered: false
                  discriminator:
                  - {path: $this, type: type}
                  min: null
                  slices:
                    valueCodeableConcept:
                      match: {}
                      schema:
                        mustSupport: true
                        choices: [valueCodeableConcept]
                        index: 42
                      min: 0
                      max: 1
              valueCodeableConcept:
                type: CodeableConcept
                mustSupport: true
                choiceOf: value
                index: 43
                slicing:
                  slices:
                    valueCodeableConcept:
                      match: {}
                      schema: {type: CodeableConcept, mustSupport: true, choiceOf: value, index: 43}
                      min: 0
                      max: 1
        three-prime-exon-id:
          match: {}
          schema:
            short: 3' Exon - Identifier
            mustSupport: true
            _required: true
            index: 62
            elements:
              code: {mustSupport: true, index: 63}
              value:
                choices: []
                index: 65
                slicing:
                  rules: open
                  ordered: false
                  discriminator:
                  - {path: $this, type: type}
                  min: null
                  slices:
                    valueCodeableConcept:
                      match: {}
                      schema:
                        mustSupport: true
                        choices: [valueCodeableConcept]
                        index: 67
                      min: 0
                      max: 1
              valueCodeableConcept:
                type: CodeableConcept
                mustSupport: true
                choiceOf: value
                index: 68
                slicing:
                  slices:
                    valueCodeableConcept:
                      match: {}
                      schema: {type: CodeableConcept, mustSupport: true, choiceOf: value, index: 68}
                      min: 0
                      max: 1
        cosmic-id:
          match: {}
          schema:
            short: RNA Fusion Cosmic-ID
            mustSupport: true
            _required: true
            index: 16
            elements:
              code: {mustSupport: true, index: 17}
              value:
                choices: []
                index: 19
                slicing:
                  rules: open
                  ordered: false
                  discriminator:
                  - {path: $this, type: type}
                  min: null
                  slices:
                    valueCodeableConcept:
                      match: {}
                      schema:
                        mustSupport: true
                        choices: [valueCodeableConcept]
                        index: 21
                      min: 0
                      max: 1
              valueCodeableConcept:
                type: CodeableConcept
                mustSupport: true
                choiceOf: value
                index: 22
                slicing:
                  slices:
                    valueCodeableConcept:
                      match: {}
                      schema: {type: CodeableConcept, mustSupport: true, choiceOf: value, index: 22}
                      min: 0
                      max: 1
        effect:
          match: {}
          schema:
            short: RNA Fusion Effect
            mustSupport: true
            _required: true
            index: 9
            elements:
              code: {mustSupport: true, index: 10}
              value:
                choices: []
                index: 12
                slicing:
                  rules: open
                  ordered: false
                  discriminator:
                  - {path: $this, type: type}
                  min: null
                  slices:
                    valueQuantity:
                      match: {}
                      schema:
                        mustSupport: true
                        choices: [valueQuantity]
                        index: 14
                      min: 0
                      max: 1
              valueQuantity:
                type: Quantity
                mustSupport: true
                choiceOf: value
                index: 15
                slicing:
                  slices:
                    valueQuantity:
                      match: {}
                      schema: {type: Quantity, mustSupport: true, choiceOf: value, index: 15}
                      min: 0
                      max: 1
package_version: 2025.0.0-ballot
class: profile
kind: resource
url: https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-pr-mtb-rna-fusion
base: https://www.medizininformatik-initiative.de/fhir/ext/modul-molgen/StructureDefinition/variante
version: 2024.0.0-ballot