{
  "description": "R4: `SubstanceProtein.disulfideLinkage` (new:string)",
  "_filename": "StructureDefinition-ext-R4-SubstanceProtein.disulfideLinkage.json",
  "package_name": "hl7.fhir.uv.xver-r4.r5",
  "date": "2026-03-17T21:02:03.8104715+00:00",
  "derivation": "constraint",
  "publisher": "FHIR Infrastructure",
  "fhirVersion": "5.0.0",
  "jurisdiction": [ {
    "coding": [ {
      "code": "001",
      "system": "http://unstats.un.org/unsd/methods/m49/m49.htm",
      "display": "World"
    } ]
  } ],
  "purpose": "This extension is part of the cross-version definitions generated to enable use of the\r\nelement `SubstanceProtein.disulfideLinkage` as defined in FHIR R4\r\nin FHIR R5.\r\n\r\nThe source element is defined as:\r\n`SubstanceProtein.disulfideLinkage` 0..* `string`\r\n\r\nAcross FHIR versions, the element set has been mapped as:\r\n* R4 `SubstanceProtein.disulfideLinkage` 0..* `string`\r\n\r\nFollowing are the generation technical comments:\r\nElement `SubstanceProtein.disulfideLinkage` is not mapped to FHIR R5, since FHIR R4 `SubstanceProtein` is not mapped.\nElement `SubstanceProtein.disulfideLinkage` has no mapping targets in FHIR R5. Typically, this is because the element has been added (is a new element).",
  "name": "ExtensionSubstanceProtein_DisulfideLinkage",
  "mapping": [ {
    "uri": "http://hl7.org/v3",
    "name": "RIM Mapping",
    "identity": "rim"
  } ],
  "abstract": false,
  "type": "Extension",
  "experimental": "false",
  "resourceType": "StructureDefinition",
  "title": "R4: The disulphide bond between two cysteine residues either on the same subunit or on two different subunits shall be described. The position of the disulfide bonds in the SubstanceProtein shall be listed in increasing order of subunit number and position within subunit followed by the abbreviation of the amino acids involved. The disulfide linkage positions shall actually contain the amino acid Cysteine at the respective positions (new)",
  "package_version": "0.1.0",
  "extension": [ {
    "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-wg",
    "valueCode": "fhir"
  }, {
    "url": "http://hl7.org/fhir/StructureDefinition/package-source",
    "extension": [ {
      "url": "packageId",
      "valueId": "hl7.fhir.uv.xver-r4.r5"
    }, {
      "url": "version",
      "valueString": "0.1.0"
    }, {
      "url": "uri",
      "valueUri": "http://hl7.org/fhir/uv/xver/ImplementationGuide/hl7.fhir.uv.xver-r4.r5"
    } ]
  }, {
    "url": "http://hl7.org/fhir/StructureDefinition/version-specific-use",
    "extension": [ {
      "url": "startFhirVersion",
      "valueCode": "5.0"
    }, {
      "url": "endFhirVersion",
      "valueCode": "5.0"
    } ]
  }, {
    "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-type-characteristics",
    "valueCode": "can-bind"
  }, {
    "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fmm",
    "valueInteger": 0,
    "_valueInteger": {
      "extension": [ {
        "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom",
        "valueCanonical": "http://hl7.org/fhir/uv/xver/ImplementationGuide/hl7.fhir.uv.xver-r4.r5"
      } ]
    }
  }, {
    "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status",
    "valueCode": "trial-use",
    "_valueCode": {
      "extension": [ {
        "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom",
        "valueCanonical": "http://hl7.org/fhir/uv/xver/ImplementationGuide/hl7.fhir.uv.xver-r4.r5"
      } ]
    }
  } ],
  "snapshot": {
    "element": [ {
      "constraint": [ {
        "key": "ele-1",
        "human": "All FHIR elements must have a @value or children",
        "source": "http://hl7.org/fhir/StructureDefinition/Element|5.0.0",
        "severity": "error",
        "expression": "hasValue() or (children().count() > id.count())"
      }, {
        "key": "ext-1",
        "human": "Must have either extensions or value[x], not both",
        "source": "http://hl7.org/fhir/StructureDefinition/Extension|5.0.0",
        "severity": "error",
        "expression": "extension.exists() != value.exists()"
      } ],
      "path": "Extension",
      "min": 0,
      "definition": "R4: `SubstanceProtein.disulfideLinkage` (new:string)",
      "isModifier": false,
      "short": "R4: The disulphide bond between two cysteine residues either on the same subunit or on two different subunits shall be described. The position of the disulfide bonds in the SubstanceProtein shall be listed in increasing order of subunit number and position within subunit followed by the abbreviation of the amino acids involved. The disulfide linkage positions shall actually contain the amino acid Cysteine at the respective positions (new)",
      "max": "*",
      "id": "Extension",
      "comment": "Element `SubstanceProtein.disulfideLinkage` is not mapped to FHIR R5, since FHIR R4 `SubstanceProtein` is not mapped.\nElement `SubstanceProtein.disulfideLinkage` has no mapping targets in FHIR R5. Typically, this is because the element has been added (is a new element).",
      "base": {
        "max": "*",
        "min": 0,
        "path": "Extension"
      }
    }, {
      "path": "Extension.id",
      "min": 0,
      "definition": "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
      "isModifier": false,
      "short": "Unique id for inter-element referencing",
      "mapping": [ {
        "map": "n/a",
        "identity": "rim"
      } ],
      "type": [ {
        "code": "http://hl7.org/fhirpath/System.String",
        "extension": [ {
          "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
          "valueUrl": "id"
        } ]
      } ],
      "representation": [ "xmlAttr" ],
      "max": "1",
      "id": "Extension.id",
      "condition": [ "ele-1" ],
      "base": {
        "max": "1",
        "min": 0,
        "path": "Element.id"
      },
      "isSummary": false
    }, {
      "constraint": [ {
        "key": "ele-1",
        "human": "All FHIR elements must have a @value or children",
        "source": "http://hl7.org/fhir/StructureDefinition/Element|5.0.0",
        "severity": "error",
        "expression": "hasValue() or (children().count() > id.count())"
      }, {
        "key": "ext-1",
        "human": "Must have either extensions or value[x], not both",
        "source": "http://hl7.org/fhir/StructureDefinition/Extension|5.0.0",
        "severity": "error",
        "expression": "extension.exists() != value.exists()"
      } ],
      "path": "Extension.extension",
      "min": 0,
      "definition": "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and managable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
      "isModifier": false,
      "short": "Additional content defined by implementations",
      "mapping": [ {
        "map": "n/a",
        "identity": "rim"
      } ],
      "slicing": {
        "rules": "open",
        "description": "Extensions are always sliced by (at least) url",
        "discriminator": [ {
          "path": "url",
          "type": "value"
        } ]
      },
      "type": [ {
        "code": "Extension"
      } ],
      "alias": [ "extensions", "user content" ],
      "max": "*",
      "id": "Extension.extension",
      "comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
      "base": {
        "max": "*",
        "min": 0,
        "path": "Element.extension"
      },
      "isSummary": false
    }, {
      "path": "Extension.url",
      "min": 1,
      "definition": "Source of the definition for the extension code - a logical name or a URL.",
      "isModifier": false,
      "short": "identifies the meaning of the extension",
      "fixedUri": "http://hl7.org/fhir/4.0/StructureDefinition/extension-SubstanceProtein.disulfideLinkage",
      "mapping": [ {
        "map": "N/A",
        "identity": "rim"
      } ],
      "type": [ {
        "code": "http://hl7.org/fhirpath/System.String",
        "extension": [ {
          "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
          "valueUrl": "uri"
        } ]
      } ],
      "representation": [ "xmlAttr" ],
      "max": "1",
      "id": "Extension.url",
      "comment": "The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.",
      "base": {
        "max": "1",
        "min": 1,
        "path": "Extension.url"
      },
      "isSummary": false
    }, {
      "constraint": [ {
        "key": "ele-1",
        "human": "All FHIR elements must have a @value or children",
        "source": "http://hl7.org/fhir/StructureDefinition/Element|5.0.0",
        "severity": "error",
        "expression": "hasValue() or (children().count() > id.count())"
      } ],
      "path": "Extension.value[x]",
      "min": 0,
      "definition": "The disulphide bond between two cysteine residues either on the same subunit or on two different subunits shall be described. The position of the disulfide bonds in the SubstanceProtein shall be listed in increasing order of subunit number and position within subunit followed by the abbreviation of the amino acids involved. The disulfide linkage positions shall actually contain the amino acid Cysteine at the respective positions.",
      "isModifier": false,
      "short": "The disulphide bond between two cysteine residues either on the same subunit or on two different subunits shall be described. The position of the disulfide bonds in the SubstanceProtein shall be listed in increasing order of subunit number and position within subunit followed by the abbreviation of the amino acids involved. The disulfide linkage positions shall actually contain the amino acid Cysteine at the respective positions",
      "mapping": [ {
        "map": "N/A",
        "identity": "rim"
      } ],
      "type": [ {
        "code": "string"
      } ],
      "max": "1",
      "id": "Extension.value[x]",
      "condition": [ "ext-1" ],
      "base": {
        "max": "1",
        "min": 0,
        "path": "Extension.value[x]"
      },
      "isSummary": false
    } ],
    "extension": [ {
      "url": "http://hl7.org/fhir/tools/StructureDefinition/snapshot-base-version",
      "valueString": "5.0.0"
    } ]
  },
  "status": "active",
  "id": "ebf77ec0-e228-4afe-b2d0-e0ffa86bebb6",
  "kind": "complex-type",
  "url": "http://hl7.org/fhir/4.0/StructureDefinition/extension-SubstanceProtein.disulfideLinkage",
  "context": [ {
    "type": "element",
    "expression": "Basic"
  } ],
  "version": "0.1.0",
  "differential": {
    "element": [ {
      "path": "Extension",
      "min": 0,
      "definition": "R4: `SubstanceProtein.disulfideLinkage` (new:string)",
      "isModifier": false,
      "short": "R4: The disulphide bond between two cysteine residues either on the same subunit or on two different subunits shall be described. The position of the disulfide bonds in the SubstanceProtein shall be listed in increasing order of subunit number and position within subunit followed by the abbreviation of the amino acids involved. The disulfide linkage positions shall actually contain the amino acid Cysteine at the respective positions (new)",
      "max": "*",
      "id": "Extension",
      "comment": "Element `SubstanceProtein.disulfideLinkage` is not mapped to FHIR R5, since FHIR R4 `SubstanceProtein` is not mapped.\nElement `SubstanceProtein.disulfideLinkage` has no mapping targets in FHIR R5. Typically, this is because the element has been added (is a new element).",
      "base": {
        "max": "*",
        "min": 0,
        "path": "Extension"
      }
    }, {
      "id": "Extension.url",
      "max": "1",
      "min": 1,
      "base": {
        "max": "1",
        "min": 1,
        "path": "Extension.url"
      },
      "path": "Extension.url",
      "fixedUri": "http://hl7.org/fhir/4.0/StructureDefinition/extension-SubstanceProtein.disulfideLinkage"
    }, {
      "id": "Extension.value[x]",
      "max": "1",
      "min": 0,
      "base": {
        "max": "1",
        "min": 0,
        "path": "Extension.value[x]"
      },
      "path": "Extension.value[x]",
      "type": [ {
        "code": "string"
      } ],
      "short": "The disulphide bond between two cysteine residues either on the same subunit or on two different subunits shall be described. The position of the disulfide bonds in the SubstanceProtein shall be listed in increasing order of subunit number and position within subunit followed by the abbreviation of the amino acids involved. The disulfide linkage positions shall actually contain the amino acid Cysteine at the respective positions",
      "definition": "The disulphide bond between two cysteine residues either on the same subunit or on two different subunits shall be described. The position of the disulfide bonds in the SubstanceProtein shall be listed in increasing order of subunit number and position within subunit followed by the abbreviation of the amino acids involved. The disulfide linkage positions shall actually contain the amino acid Cysteine at the respective positions."
    } ]
  },
  "contact": [ {
    "name": "FHIR Infrastructure",
    "telecom": [ {
      "value": "http://www.hl7.org/Special/committees/fiwg",
      "system": "url"
    } ]
  } ],
  "baseDefinition": "http://hl7.org/fhir/StructureDefinition/Extension|5.0.0"
}