{
  "description": null,
  "_filename": "example/EvidenceVariable-ExampleRecommendationEligibilityCriteriaDrugs.json",
  "package_name": "de.netzwerk-universitaetsmedizin.ebm-cpg",
  "date": "2025-03-04T10:04:34+00:00",
  "meta": {
    "profile": [ "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/StructureDefinition/recommendation-eligibility-criteria" ]
  },
  "publisher": null,
  "name": "PopulationExample",
  "type": null,
  "experimental": null,
  "resourceType": "EvidenceVariable",
  "title": null,
  "package_version": "1.2.0",
  "characteristic": [ {
    "definitionByCombination": {
      "code": "all-of",
      "characteristic": [ {
        "definitionByCombination": {
          "code": "all-of",
          "characteristic": [ {
            "definitionByTypeAndValue": {
              "type": {
                "coding": [ {
                  "code": "18629005",
                  "system": "http://snomed.info/sct",
                  "display": "Administration of drug or medicament (procedure)"
                } ]
              },
              "extension": [ {
                "url": "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/StructureDefinition/ext-characteristic-dosage",
                "valueDosage": {
                  "route": {
                    "coding": [ {
                      "code": "26643006",
                      "system": "http://snomed.info/sct",
                      "display": "Oral route"
                    } ]
                  },
                  "timing": {
                    "repeat": {
                      "count": 10,
                      "period": 1,
                      "duration": 10,
                      "frequency": 1,
                      "periodUnit": "d",
                      "durationUnit": "d"
                    }
                  },
                  "extension": [ {
                    "url": "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/StructureDefinition/ext-dosage-condition",
                    "extension": [ {
                      "url": "type",
                      "valueCodeableConcept": {
                        "coding": [ {
                          "code": "29463-7",
                          "system": "http://loinc.org",
                          "display": "Body weight"
                        } ]
                      }
                    }, {
                      "url": "value",
                      "valueRange": {
                        "high": {
                          "code": "kg",
                          "unit": "kg",
                          "value": 70,
                          "system": "http://unitsofmeasure.org"
                        }
                      }
                    } ]
                  } ],
                  "doseAndRate": [ {
                    "doseQuantity": {
                      "code": "mg",
                      "unit": "mg",
                      "value": 6,
                      "system": "http://unitsofmeasure.org"
                    },
                    "rateQuantity": {
                      "code": "/d",
                      "unit": "/d",
                      "value": 1,
                      "system": "http://unitsofmeasure.org"
                    }
                  } ]
                }
              } ],
              "valueCodeableConcept": {
                "coding": [ {
                  "code": "372877000",
                  "system": "http://snomed.info/sct",
                  "display": "Heparin (substance)"
                } ]
              }
            }
          } ]
        }
      } ]
    }
  } ],
  "status": "active",
  "id": "e989f1be-8d41-4563-8bbe-5f1249e0d4e8",
  "kind": null,
  "url": "https://www.netzwerk-universitaetsmedizin.de/fhir/cpg-on-ebm-on-fhir/example/recommendation-eligibility-criteria-drugs",
  "version": null
}