description: DNA-Fusion
package_name: rs/de.medizininformatikinitiative.kerndatensatz.mtb
derivation: constraint
name: MII_PR_MTB_DNA_Fusion
type: Observation
elements:
  meta:
    mustSupport: true
    index: 0
    elements:
      profile: {mustSupport: true, index: 1}
  identifier: {short: VariantenId im Kontext des NGS-Befundes, mustSupport: true, index: 2}
  focus:
    type: Reference
    mustSupport: true
    refers: ['https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-pr-mtb-diagnose-primaertumor', 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-diagnose-primaertumor']
    index: 3
  component:
    array: true
    min: 6
    index: 4
    slicing:
      slices:
        allelic-read-depth:
          match: {}
          schema:
            short: Number reported reads
            index: 5
            elements:
              code: {mustSupport: true, index: 6}
              value:
                mustSupport: true
                choices: []
                index: 8
        five-prime-chromosome:
          match: {}
          schema:
            short: 5' Domain - Chromosom
            mustSupport: true
            _required: true
            index: 9
            elements:
              code:
                pattern:
                  type: CodeableConcept
                  value:
                    coding:
                    - {code: five-prime-chromosome, system: 'https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/CodeSystem/mii-cs-mtb-molekulare-biomarker'}
                type: CodeableConcept
                index: 10
              value:
                choices: []
                index: 12
                slicing:
                  rules: open
                  ordered: false
                  discriminator:
                  - {path: $this, type: type}
                  min: null
                  slices:
                    valueCodeableConcept:
                      match: {}
                      schema:
                        mustSupport: true
                        choices: [valueCodeableConcept]
                        index: 14
                      min: 0
                      max: 1
              valueCodeableConcept:
                type: CodeableConcept
                mustSupport: true
                choiceOf: value
                index: 15
                slicing:
                  slices:
                    valueCodeableConcept:
                      match: {}
                      schema: {type: CodeableConcept, mustSupport: true, choiceOf: value, index: 15}
                      min: 0
                      max: 1
        three-prime-chromosome:
          match: {}
          schema:
            short: 3' Domain - Chromosom
            mustSupport: true
            _required: true
            index: 16
            elements:
              code:
                mustSupport: true
                pattern:
                  type: CodeableConcept
                  value:
                    coding:
                    - {code: three-prime-chromosome, system: 'https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/CodeSystem/mii-cs-mtb-molekulare-biomarker'}
                type: CodeableConcept
                index: 17
              value:
                choices: []
                index: 19
                slicing:
                  rules: open
                  ordered: false
                  discriminator:
                  - {path: $this, type: type}
                  min: null
                  slices:
                    valueCodeableConcept:
                      match: {}
                      schema:
                        mustSupport: true
                        choices: [valueCodeableConcept]
                        index: 21
                      min: 0
                      max: 1
              valueCodeableConcept:
                type: CodeableConcept
                mustSupport: true
                choiceOf: value
                index: 22
                slicing:
                  slices:
                    valueCodeableConcept:
                      match: {}
                      schema: {type: CodeableConcept, mustSupport: true, choiceOf: value, index: 22}
                      min: 0
                      max: 1
        five-prime-position:
          match: {}
          schema:
            short: 5' Domain - Position
            mustSupport: true
            _required: true
            index: 23
            elements:
              code:
                mustSupport: true
                pattern:
                  type: CodeableConcept
                  value:
                    coding:
                    - {code: five-prime-position, system: 'https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/CodeSystem/mii-cs-mtb-molekulare-biomarker'}
                type: CodeableConcept
                index: 24
              value:
                choices: []
                index: 26
                slicing:
                  rules: open
                  ordered: false
                  discriminator:
                  - {path: $this, type: type}
                  min: null
                  slices:
                    valueRange:
                      match: {}
                      schema:
                        mustSupport: true
                        choices: [valueRange]
                        index: 28
                      min: 0
                      max: 1
              valueRange:
                type: Range
                mustSupport: true
                choiceOf: value
                index: 29
                slicing:
                  slices:
                    valueRange:
                      match: {}
                      schema: {type: Range, mustSupport: true, choiceOf: value, index: 29}
                      min: 0
                      max: 1
        three-prime-position:
          match: {}
          schema:
            short: 3' Domain - Position
            mustSupport: true
            _required: true
            index: 30
            elements:
              code:
                mustSupport: true
                pattern:
                  type: CodeableConcept
                  value:
                    coding:
                    - {code: three-prime-position, system: 'https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/CodeSystem/mii-cs-mtb-molekulare-biomarker'}
                type: CodeableConcept
                index: 31
        five-prime-gene:
          match: {}
          schema:
            short: 5' Domain - Gen
            mustSupport: true
            _required: true
            index: 32
            elements:
              code:
                mustSupport: true
                pattern:
                  type: CodeableConcept
                  value:
                    coding:
                    - {code: five-prime-gene, system: 'https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/CodeSystem/mii-cs-mtb-molekulare-biomarker'}
                type: CodeableConcept
                index: 33
        three-prime-gene:
          match: {}
          schema:
            short: 3' Domain - Gen
            mustSupport: true
            _required: true
            index: 34
            elements:
              code:
                mustSupport: true
                pattern:
                  type: CodeableConcept
                  value:
                    coding:
                    - {code: three-prime-gene, system: 'https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/CodeSystem/mii-cs-mtb-molekulare-biomarker'}
                type: CodeableConcept
                index: 35
              value:
                choices: []
                index: 37
                slicing:
                  rules: open
                  ordered: false
                  discriminator:
                  - {path: $this, type: type}
                  min: null
                  slices:
                    valueCodeableConcept:
                      match: {}
                      schema:
                        mustSupport: true
                        choices: [valueCodeableConcept]
                        index: 39
                      min: 0
                      max: 1
              valueCodeableConcept:
                type: CodeableConcept
                mustSupport: true
                choiceOf: value
                index: 40
                slicing:
                  slices:
                    valueCodeableConcept:
                      match: {}
                      schema: {type: CodeableConcept, mustSupport: true, choiceOf: value, index: 40}
                      min: 0
                      max: 1
package_version: 2025.0.0-ballot
class: profile
kind: resource
url: https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-pr-mtb-dna-fusion
base: https://www.medizininformatik-initiative.de/fhir/ext/modul-molgen/StructureDefinition/variante
version: 2024.0.0-ballot