{
  "description": "The relationship between two substance types.",
  "_filename": "CodeSystem-substance-relationship-type.json",
  "package_name": "hl7.fhir.r6.core",
  "date": "2021-01-05T10:01:24+11:00",
  "meta": {
    "lastUpdated": "2026-07-17T18:22:54.721+11:00"
  },
  "publisher": "HL7 (FHIR Project)",
  "jurisdiction": [ {
    "coding": [ {
      "code": "001",
      "system": "http://unstats.un.org/unsd/methods/m49/m49.htm",
      "display": "World"
    } ]
  } ],
  "content": "complete",
  "name": "SubstanceRelationshipTypeExample",
  "type": null,
  "experimental": "true",
  "resourceType": "CodeSystem",
  "title": "Substance Relationship Type",
  "package_version": "6.0.0-ballot5",
  "extension": [ {
    "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-wg",
    "valueCode": "brr"
  }, {
    "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status",
    "valueCode": "informative"
  }, {
    "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fmm",
    "valueInteger": 1
  } ],
  "status": "active",
  "id": "d2287cc9-f05f-4528-a390-a1b5aa59b669",
  "valueSet": "http://hl7.org/fhir/ValueSet/substance-relationship-type",
  "kind": null,
  "url": "http://hl7.org/fhir/substance-relationship-type",
  "identifier": [ {
    "value": "urn:oid:2.16.840.1.113883.4.642.4.2088",
    "system": "urn:ietf:rfc:3986"
  } ],
  "concept": [ {
    "code": "Salt",
    "display": "Salt to parent"
  }, {
    "code": "ActiveMoiety",
    "display": "Active moiety"
  }, {
    "code": "StartingMaterial",
    "display": "Starting material for"
  }, {
    "code": "Polymorph",
    "display": "Polymorph of"
  }, {
    "code": "Impurity",
    "display": "Impurity of"
  }, {
    "code": "TherapeuticTarget",
    "display": "Therapeutic target",
    "definition": "The substance acts therapeutically on the target."
  }, {
    "code": "MetabolicTarget",
    "display": "Metabolic target",
    "definition": "The substance is metabolised by or interacts with the target as part of metabolism."
  }, {
    "code": "ToxicityTarget",
    "display": "Toxicity target",
    "definition": "The substance interacts with the target in a way that contributes to toxicity."
  }, {
    "code": "TargetUnknownEffect",
    "display": "Target (unknown effect)",
    "definition": "The substance is known to interact with the target, but the effect is not characterised."
  }, {
    "code": "GeneOfOrigin",
    "display": "Gene of origin",
    "definition": "The substance was derived from this gene (used e.g. for recombinant proteins and nucleic acid products)."
  }, {
    "code": "Component",
    "display": "Component",
    "definition": "The substance is a component (constituent) of a mixture substance. Used to relate a mixture's component substances to the mixture itself."
  } ],
  "caseSensitive": true,
  "version": "6.0.0-ballot5",
  "contact": [ {
    "telecom": [ {
      "value": "http://hl7.org/fhir",
      "system": "url"
    }, {
      "value": "fhir@lists.hl7.org",
      "system": "email"
    } ]
  } ]
}