description: Profile with properties for observations that convey the potential impact of genomic characteristics on a medication or non-medicinal therapy.
package_name: hl7.fhir.uv.genomics
derivation: constraint
name: TherapeuticImplication
type: Observation
elements:
  code:
    elements:
      coding:
        elements:
          system:
            pattern: {type: Uri, value: 'http://hl7.org/fhir/uv/genomics-reporting/CodeSystem/TbdCodes'}
            index: 0
          code:
            pattern: {type: Code, value: therapeutic-implication}
            index: 1
  component:
    short: Associated phenotype
    array: true
    index: 2
    slicing:
      slices:
        associated-phenotype:
          match: {}
          schema:
            short: Associated phenotype
            array: true
            index: 2
            elements:
              code:
                pattern:
                  type: CodeableConcept
                  value:
                    coding:
                    - {code: 81259-4, system: 'http://loinc.org'}
                index: 3
              value:
                choices: [valueCodeableConcept]
                index: 5
              valueCodeableConcept: {type: CodeableConcept, choiceOf: value, index: 6}
            required: [value, valueCodeableConcept]
        associated-cancer:
          match: {}
          schema:
            short: Associated cancer
            array: true
            index: 7
            elements:
              code:
                pattern:
                  type: CodeableConcept
                  value:
                    coding:
                    - {code: associated-cancer, system: 'http://hl7.org/fhir/uv/genomics-reporting/CodeSystem/TbdCodes'}
                index: 8
              value:
                choices: [valueCodeableConcept]
                index: 10
              valueCodeableConcept: {type: CodeableConcept, choiceOf: value, index: 11}
            required: [value, valueCodeableConcept]
        medication-assessed:
          match: {}
          schema:
            short: Medication Assessed
            array: true
            index: 12
            elements:
              code:
                pattern:
                  type: CodeableConcept
                  value:
                    coding:
                    - {code: 51963-7, system: 'http://loinc.org'}
                index: 13
              value:
                choices: [valueCodeableConcept]
                index: 15
              valueCodeableConcept: {type: CodeableConcept, choiceOf: value, index: 16}
            required: [value, valueCodeableConcept]
        therapy-assessed:
          match: {}
          schema:
            short: Associated cancer
            array: true
            index: 17
            elements:
              code:
                pattern:
                  type: CodeableConcept
                  value:
                    coding:
                    - {code: associated-therapy, system: 'http://hl7.org/fhir/uv/genomics-reporting/CodeSystem/TbdCodes'}
                index: 18
              value:
                choices: [valueCodeableConcept]
                index: 20
              valueCodeableConcept: {type: CodeableConcept, choiceOf: value, index: 21}
            required: [value, valueCodeableConcept]
        effect-medication-metabolism:
          match: {}
          schema:
            short: Effect medication metabolism
            index: 22
            elements:
              code:
                pattern:
                  type: CodeableConcept
                  value:
                    coding:
                    - {code: 53040-2, system: 'http://loinc.org'}
                index: 23
              value:
                choices: [valueCodeableConcept]
                index: 25
              valueCodeableConcept: {type: CodeableConcept, choiceOf: value, index: 26}
            required: [value, valueCodeableConcept]
        effect-medication-high-risk:
          match: {}
          schema:
            short: Effect medication high risk
            index: 27
            elements:
              code:
                pattern:
                  type: CodeableConcept
                  value:
                    coding:
                    - {code: 83009-1, system: 'http://loinc.org'}
                index: 28
              value:
                choices: [valueCodeableConcept]
                index: 30
              valueCodeableConcept: {type: CodeableConcept, choiceOf: value, index: 31}
            required: [value, valueCodeableConcept]
        effect-medication-efficacy:
          match: {}
          schema:
            short: Effect medication high risk
            array: true
            index: 32
            elements:
              code:
                pattern:
                  type: CodeableConcept
                  value:
                    coding:
                    - {code: 51961-1, system: 'http://loinc.org'}
                index: 33
              value:
                choices: [valueCodeableConcept]
                index: 35
              valueCodeableConcept: {type: CodeableConcept, choiceOf: value, index: 36}
            required: [value, valueCodeableConcept]
package_version: reporting-1.1.0
class: profile
kind: resource
url: http://hl7.org/fhir/uv/genomics-reporting/StructureDefinition/therapeutic-implication
base: http://hl7.org/fhir/uv/genomics-reporting/StructureDefinition/implication
version: 1.1.0