{
  "description": "ClinVar contains examples of evidence level concepts that are not conflated with clinical significance. These can be found on  ClinVar https://www.ncbi.nlm.nih.gov/clinvar/docs/review_status/ . These examples are informational only, for copyright information contact the relevant source.",
  "_filename": "CodeSystem-clinvar-evidence-level-custom-cs.json",
  "package_name": "hl7.fhir.uv.genomics-reporting",
  "date": "2024-12-12T20:43:36+00:00",
  "publisher": "HL7 International / Clinical Genomics",
  "jurisdiction": [ {
    "coding": [ {
      "code": "001",
      "system": "http://unstats.un.org/unsd/methods/m49/m49.htm",
      "display": "World"
    } ]
  } ],
  "content": "complete",
  "name": "ClinVarEvidenceLevelCustomCS",
  "type": null,
  "experimental": "true",
  "resourceType": "CodeSystem",
  "title": "ClinVar Evidence Level Example Codes",
  "package_version": "3.0.0",
  "extension": [ {
    "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-wg",
    "valueCode": "cg"
  } ],
  "status": "active",
  "id": "b7d4990f-c6e0-40fd-805e-d1e8e7dbcccb",
  "kind": null,
  "count": 5,
  "url": "http://hl7.org/fhir/uv/genomics-reporting/CodeSystem/clinvar-evidence-level-custom-cs",
  "concept": [ {
    "code": "4-star",
    "display": "4 star",
    "definition": "Supported by practice guideline"
  }, {
    "code": "3-star",
    "display": "3 star",
    "definition": "Supported by expert panel review"
  }, {
    "code": "2-star",
    "display": "2 star",
    "definition": "Supported by submission by multiple-submitters with documentation of criteria for assertion"
  }, {
    "code": "1-star",
    "display": "1 star",
    "definition": "Single submitter providing interpretation and documentation of criteria for assertion"
  }, {
    "code": "no-star",
    "display": "no star",
    "definition": "submitted, no evidence"
  } ],
  "caseSensitive": true,
  "version": "3.0.0",
  "contact": [ {
    "name": "HL7 International / Clinical Genomics",
    "telecom": [ {
      "value": "http://www.hl7.org/Special/committees/clingenomics",
      "system": "url"
    }, {
      "value": "cg@lists.HL7.org",
      "system": "email"
    } ]
  } ]
}