description: Beschreibt die Gesamtzahl von in Krebszellen gefundenen Mutationen pro 1 Mio. Basen.
package_name: de.medizininformatikinitiative.kerndatensatz.mtb
derivation: constraint
name: MII_PR_MTB_Mutationslast
type: Observation
elements:
  category: {mustSupport: true, index: 1}
  interpretation:
    binding: {strength: required, valueSet: 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/high-low-codes-vs'}
    mustSupport: true
    index: 9
  encounter: {mustSupport: true, index: 5}
  specimen: {mustSupport: true, index: 10}
  valueQuantity: {type: Quantity, mustSupport: true, choiceOf: value, index: 8}
  value:
    mustSupport: true
    choices: [valueQuantity]
    index: 7
  status: {mustSupport: true, index: 0}
  code:
    mustSupport: true
    index: 2
    elements:
      coding:
        mustSupport: true
        pattern:
          type: Coding
          value: {code: 94076-7, system: 'http://loinc.org', display: 'Mutations/Megabase [# Ratio] in Tumor'}
        type: Coding
        index: 3
  subject:
    type: Reference
    mustSupport: true
    refers: ['http://hl7.org/fhir/StructureDefinition/Patient']
    index: 4
package_version: 2025.0.0-ballot
class: profile
kind: resource
url: https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-pr-mtb-mutationslast
base: https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-pr-mtb-molekularer-biomarker
version: 2024.0.0-ballot
required: [subject]