description: The Evidence Resource provides a machine-interpretable expression of an evidence concept including the evidence variables (e.g., population, exposures/interventions, comparators, outcomes, measured variables, confounding variables), the statistics, and the certainty of this evidence. package_name: hl7.fhir.r6.core derivation: specialization name: Evidence type: Evidence elements: description: {isModifier: false, short: Description of the particular summary, type: markdown, mustSupport: false, isSummary: true, index: 35} statistic: isModifier: false short: Values and parameters for a single statistic type: BackboneElement mustSupport: false array: true isSummary: false index: 49 elements: description: {isModifier: false, short: A natural language summary of the statistic, type: markdown, mustSupport: false, isSummary: false, index: 50} category: {isModifier: false, short: Associated category for categorical variable, type: CodeableConcept, mustSupport: false, isSummary: false, index: 53} attributeEstimate: isModifier: false short: An attribute of the Statistic type: BackboneElement mustSupport: false array: true isSummary: false index: 64 elements: description: {isModifier: false, short: Textual description of the attribute estimate, type: markdown, mustSupport: false, isSummary: false, index: 65} note: {isModifier: false, short: Footnote or explanatory note about the estimate, type: Annotation, mustSupport: false, array: true, isSummary: false, index: 66} type: isModifier: false short: The type of attribute estimate, e.g., confidence interval or p value type: CodeableConcept mustSupport: false binding: {strength: example, valueSet: 'http://terminology.hl7.org/ValueSet/attribute-estimate-type'} isSummary: false index: 67 quantity: {isModifier: false, short: 'The singular quantity of the attribute estimate, for attribute estimates represented as single values, which may include a unit of measure', type: Quantity, mustSupport: false, isSummary: false, index: 68} level: {isModifier: false, short: 'Level of confidence interval, e.g., 0.95 for 95% confidence interval', type: decimal, mustSupport: false, isSummary: false, index: 69} range: {isModifier: false, short: Lower and upper bound values of the attribute estimate, type: Range, mustSupport: false, isSummary: false, index: 70} attributeEstimate: elementReference: ['http://hl7.org/fhir/StructureDefinition/Evidence', elements, statistic, elements, attributeEstimate] isModifier: false short: A nested attribute estimate; which is the attribute estimate of an attribute estimate mustSupport: false array: true isSummary: false index: 71 sampleSize: isModifier: false short: Count of participants in the study sample type: BackboneElement mustSupport: false isSummary: false index: 57 elements: description: {isModifier: false, short: Textual description of sample size for statistic, type: markdown, mustSupport: false, isSummary: false, index: 58} note: {isModifier: false, short: Footnote or explanatory note about the sample size, type: Annotation, mustSupport: false, array: true, isSummary: false, index: 59} numberOfStudies: {isModifier: false, short: Number of contributing studies, type: unsignedInt, mustSupport: false, isSummary: false, index: 60} numberOfParticipants: {isModifier: false, short: Total number of participants, type: unsignedInt, mustSupport: false, isSummary: false, index: 61} knownDataCount: {isModifier: false, short: Number of participants with known results for measured variables, type: unsignedInt, mustSupport: false, isSummary: false, index: 62} numberAnalyzed: {isModifier: false, short: Total number of participants who were analayzed, type: unsignedInt, mustSupport: false, isSummary: false, index: 63} note: {isModifier: false, short: Footnotes and/or explanatory notes, type: Annotation, mustSupport: false, array: true, isSummary: false, index: 51} modelCharacteristic: isModifier: false short: An aspect of the statistical model index: 72 type: BackboneElement mustSupport: false array: true elements: attribute: elementReference: ['http://hl7.org/fhir/StructureDefinition/Evidence', elements, statistic, elements, attributeEstimate] isModifier: false short: An attribute of the model characteristic mustSupport: false array: true isSummary: false index: 87 variable: isModifier: false short: A variable adjusted for in the adjusted analysis index: 81 type: BackboneElement mustSupport: false array: true elements: variableDefinition: isModifier: false short: Description and definition of the variable refers: ['http://hl7.org/fhir/StructureDefinition/EvidenceVariable', 'http://hl7.org/fhir/StructureDefinition/Group'] type: Reference mustSupport: false isSummary: false index: 82 handling: isModifier: false short: boolean | continuous | dichotomous | ordinal | polychotomous | time-to-event | not-specified type: CodeableConcept mustSupport: false binding: {strength: example, valueSet: 'http://hl7.org/fhir/ValueSet/variable-handling-example'} isSummary: false index: 83 valueCategory: {isModifier: false, short: 'Qualitative label used for grouping values of a dichotomous, ordinal, or polychotomous variable', type: CodeableConcept, mustSupport: false, array: true, isSummary: false, index: 84} valueQuantity: {isModifier: false, short: 'Quantitative label used for grouping values of a dichotomous, ordinal, or polychotomous variable', type: Quantity, mustSupport: false, array: true, isSummary: false, index: 85} valueRange: {isModifier: false, short: 'Range of quantitative labels used for grouping values of a dichotomous, ordinal, or polychotomous variable', type: Range, mustSupport: false, array: true, isSummary: false, index: 86} required: [variableDefinition] isSummary: false applied: {isModifier: false, short: 'This model characteristic is part of the analysis that was applied, whether or not the analysis followed the plan', type: boolean, mustSupport: false, meaningWhenMissing: 'True, unless modelCharacteristic.intended = true; if modelCharacteristic.intended = true and .applied is missing, then meaning Unknown.', isSummary: false, index: 80} valueQuantity: {isModifier: false, short: The specific value (when paired with code), type: Quantity, mustSupport: false, choiceOf: value, isSummary: false, index: 76} value: isModifier: false short: The specific value (when paired with code) mustSupport: false choices: [valueQuantity, valueRange, valueCodeableConcept] isSummary: false index: 75 code: isModifier: false short: Model specification type: CodeableConcept mustSupport: false binding: {strength: example, valueSet: 'http://terminology.hl7.org/ValueSet/statistic-model-code'} isSummary: false index: 73 valueCodeableConcept: {isModifier: false, short: The specific value (when paired with code), type: CodeableConcept, mustSupport: false, choiceOf: value, isSummary: false, index: 78} valueRange: {isModifier: false, short: The specific value (when paired with code), type: Range, mustSupport: false, choiceOf: value, isSummary: false, index: 77} intended: {isModifier: false, short: The plan for analysis, type: boolean, mustSupport: false, isSummary: false, index: 79} required: [code] isSummary: false statisticType: isModifier: false short: Type of statistic, e.g., relative risk type: CodeableConcept mustSupport: false binding: {strength: example, valueSet: 'http://terminology.hl7.org/ValueSet/statistic-type'} isSummary: true index: 52 numberAffected: {isModifier: false, short: The number of participants affected, type: unsignedInt, mustSupport: false, isSummary: false, index: 56} quantity: {isModifier: false, short: Statistic value, type: Quantity, mustSupport: false, isSummary: true, index: 54} numberOfEvents: {isModifier: false, short: The number of events associated with the statistic, type: unsignedInt, mustSupport: false, isSummary: false, index: 55} date: {isModifier: false, short: Date last changed, type: dateTime, mustSupport: false, isSummary: true, index: 12} endorser: {isModifier: false, short: Who endorsed the content, type: ContactDetail, mustSupport: false, array: true, isSummary: false, index: 21} publisher: {isModifier: false, short: Name of the publisher/steward (organization or individual), type: string, mustSupport: false, isSummary: true, index: 16} approvalDate: {isModifier: false, short: When the summary was approved by publisher, type: date, mustSupport: false, isSummary: false, index: 13} purpose: {isModifier: false, short: Why this Evidence is defined, type: markdown, mustSupport: false, isSummary: false, index: 23} name: {isModifier: false, short: Name for this summary (machine friendly), type: string, mustSupport: false, isSummary: false, index: 7} citeAs: {isModifier: false, short: Display of how to cite this Evidence, type: markdown, mustSupport: false, isSummary: false, index: 9} copyrightLabel: {isModifier: false, short: Copyright holder and year(s), type: string, mustSupport: false, isSummary: false, index: 25} useContext: {isModifier: false, short: The context that the content is intended to support, type: UsageContext, mustSupport: false, array: true, isSummary: true, index: 22} copyright: {isModifier: false, short: 'Intellectual property ownership, may include restrictions on use', type: markdown, mustSupport: false, isSummary: false, index: 24} versionAlgorithm: isModifier: false short: How to compare versions mustSupport: false choices: [versionAlgorithmString, versionAlgorithmCoding] isSummary: true index: 4 experimental: {isModifier: false, short: For testing only - never for real usage, type: boolean, mustSupport: false, meaningWhenMissing: 'If absent, this resource is treated as though it is not experimental.', isSummary: false, index: 11} variableDefinition: isModifier: false short: Description, classification, and definition of a single variable index: 38 type: BackboneElement mustSupport: false array: true elements: description: {isModifier: false, short: A text description or summary of the variable, type: markdown, mustSupport: false, isSummary: false, index: 39} note: {isModifier: false, short: Footnotes and/or explanatory notes, type: Annotation, mustSupport: false, array: true, isSummary: false, index: 40} variableRole: isModifier: false short: population | exposure | outcome | covariate type: code mustSupport: false binding: {strength: required, valueSet: 'http://hl7.org/fhir/ValueSet/variable-role|6.0.0-ballot4'} isSummary: true index: 41 roleSubtype: isModifier: false short: Sub-classification of the role of the variable type: CodeableConcept mustSupport: false binding: {strength: example, valueSet: 'http://terminology.hl7.org/ValueSet/variable-role-subtype'} isSummary: false index: 42 comparatorCategory: {isModifier: false, short: The reference value used for comparison, type: string, mustSupport: false, isSummary: false, index: 43} observed: isModifier: false short: Definition of the actual variable related to the statistic(s) refers: ['http://hl7.org/fhir/StructureDefinition/EvidenceVariable', 'http://hl7.org/fhir/StructureDefinition/Group'] type: Reference mustSupport: false isSummary: true index: 44 intended: isModifier: false short: Definition of the intended variable related to the Evidence refers: ['http://hl7.org/fhir/StructureDefinition/EvidenceVariable', 'http://hl7.org/fhir/StructureDefinition/Group'] type: Reference mustSupport: false isSummary: false index: 45 directnessMatch: isModifier: false short: low | moderate | high | exact type: CodeableConcept mustSupport: false binding: {strength: example, valueSet: 'http://terminology.hl7.org/ValueSet/directness'} isSummary: false index: 46 required: [variableRole] isSummary: false title: {isModifier: false, short: Name for this summary (human friendly), type: string, mustSupport: false, isSummary: true, index: 8} note: {isModifier: false, short: Footnotes and/or explanatory notes, type: Annotation, mustSupport: false, array: true, isSummary: false, index: 37} author: {isModifier: false, short: Who authored the content, type: ContactDetail, mustSupport: false, array: true, isSummary: true, index: 15} synthesisType: isModifier: false short: The design of the synthesis (combination of studies) that produced this evidence type: CodeableConcept mustSupport: false array: true binding: {strength: example, valueSet: 'http://terminology.hl7.org/ValueSet/synthesis-type'} isSummary: false index: 47 versionAlgorithmCoding: {isModifier: false, short: How to compare versions, type: Coding, mustSupport: false, choiceOf: versionAlgorithm, isSummary: true, index: 6} status: isModifier: true short: draft | active | retired | unknown index: 10 type: code mustSupport: false binding: {strength: required, valueSet: 'http://hl7.org/fhir/ValueSet/publication-status|6.0.0-ballot4'} isModifierReason: This is labeled as "Is Modifier" because applications should not use a retired Evidence without due consideration isSummary: true recorder: {isModifier: false, short: Who entered the data for the evidence, type: ContactDetail, mustSupport: false, array: true, isSummary: false, index: 18} url: constraint: cnl-1: {human: 'URL should not contain | or # - these characters make processing canonical references problematic', source: 'http://hl7.org/fhir/StructureDefinition/Evidence', severity: warning, expression: 'exists() implies matches(''^[^|# ]+$'')'} isModifier: false short: Canonical identifier for this evidence, represented as a globally unique URI type: uri mustSupport: false isSummary: true index: 0 identifier: {isModifier: false, short: Additional identifier for the summary, type: Identifier, mustSupport: false, array: true, isSummary: true, index: 1} lastReviewDate: {isModifier: false, short: When the summary was last reviewed by the publisher, type: date, mustSupport: false, isSummary: false, index: 14} editor: {isModifier: false, short: Who edited the content, type: ContactDetail, mustSupport: false, array: true, isSummary: false, index: 19} relatesTo: isModifier: false short: Relationships to other Resources index: 26 type: BackboneElement mustSupport: false array: true elements: type: isModifier: false short: documentation | justification | citation | predecessor | successor | derived-from | depends-on | composed-of | part-of | amends | amended-with | appends | appended-with | cites | cited-by | comments-on | comment-in | contains | contained-in | corrects | correction-in | replaces | replaced-with | retracts | retracted-by | signs | similar-to | supports | supported-with | transforms | transformed-into | transformed-with | documents | specification-of | created-with | cite-as | reprint | reprint-of | summarizes type: CodeableConcept mustSupport: false binding: {strength: extensible, valueSet: 'http://terminology.hl7.org/ValueSet/artifact-relationship-type'} isSummary: false index: 27 target: isModifier: false short: The artifact that is related to this Evidence mustSupport: false choices: [targetUri, targetAttachment, targetCanonical, targetReference, targetMarkdown] isSummary: false index: 29 targetUri: {isModifier: false, short: The artifact that is related to this Evidence, type: uri, mustSupport: false, choiceOf: target, isSummary: false, index: 30} targetAttachment: {isModifier: false, short: The artifact that is related to this Evidence, type: Attachment, mustSupport: false, choiceOf: target, isSummary: false, index: 31} targetCanonical: {isModifier: false, short: The artifact that is related to this Evidence, type: canonical, mustSupport: false, choiceOf: target, isSummary: false, index: 32} targetReference: isModifier: false short: The artifact that is related to this Evidence index: 33 refers: ['http://hl7.org/fhir/StructureDefinition/Resource'] type: Reference mustSupport: false choiceOf: target isSummary: false targetMarkdown: {isModifier: false, short: The artifact that is related to this Evidence, type: markdown, mustSupport: false, choiceOf: target, isSummary: false, index: 34} required: [targetCanonical, targetMarkdown, targetReference, type, target, targetAttachment, targetUri] isSummary: false versionAlgorithmString: {isModifier: false, short: How to compare versions, type: string, mustSupport: false, choiceOf: versionAlgorithm, isSummary: true, index: 5} certainty: isModifier: false short: Certainty or quality of the evidence type: BackboneElement mustSupport: false array: true isSummary: false index: 88 elements: description: {isModifier: false, short: Textual description of certainty, type: markdown, mustSupport: false, isSummary: false, index: 89} note: {isModifier: false, short: Footnotes and/or explanatory notes, type: Annotation, mustSupport: false, array: true, isSummary: false, index: 90} type: isModifier: false short: Aspect of certainty being rated type: CodeableConcept mustSupport: false binding: {strength: example, valueSet: 'http://terminology.hl7.org/ValueSet/certainty-type'} isSummary: false index: 91 rating: isModifier: false short: Assessment or judgement of the aspect type: CodeableConcept mustSupport: false binding: {strength: example, valueSet: 'http://terminology.hl7.org/ValueSet/certainty-rating'} isSummary: false index: 92 rater: {isModifier: false, short: Individual or group who did the rating, type: string, mustSupport: false, array: true, isSummary: false, index: 93} subcomponent: elementReference: ['http://hl7.org/fhir/StructureDefinition/Evidence', elements, certainty] isModifier: false short: A domain or subdomain of certainty mustSupport: false array: true isSummary: false index: 94 reviewer: {isModifier: false, short: Who reviewed the content, type: ContactDetail, mustSupport: false, array: true, isSummary: false, index: 20} version: {isModifier: false, short: Business version of this summary, type: string, mustSupport: false, isSummary: true, index: 2} studyDesign: isModifier: false short: The design of the study that produced this evidence type: CodeableConcept mustSupport: false array: true binding: {strength: extensible, valueSet: 'http://hl7.org/fhir/ValueSet/study-design'} isSummary: false index: 48 contact: {isModifier: false, short: Contact details for the publisher, type: ContactDetail, mustSupport: false, array: true, isSummary: true, index: 17} assertion: {isModifier: false, short: Declarative description of the Evidence, type: markdown, mustSupport: false, isSummary: false, index: 36} package_version: 6.0.0-ballot4 class: resource kind: resource url: http://hl7.org/fhir/StructureDefinition/Evidence base: http://hl7.org/fhir/StructureDefinition/DomainResource version: 6.0.0-ballot4 required: [status]