PackagesCanonicalsLogsProblems
    Packages
    de.medizininformatikinitiative.kerndatensatz.onkologie@2026.0.0-ballot
    https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/CodeSystem/mii-cs-onko-weitere-klassifikationen-obds
{
  "description": "oBDS-specific classification systems and scoring systems not yet covered by international terminologies (SNOMED CT, NCI Thesaurus). These codes supplement the existing ValueSet for additional classifications. Research required: Check if SNOMED CT or LOINC codes exist for these scoring systems before using oBDS-specific codes.",
  "_filename": "CodeSystem-mii-cs-onko-weitere-klassifikationen-obds.json",
  "package_name": "de.medizininformatikinitiative.kerndatensatz.onkologie",
  "date": null,
  "publisher": "Medizininformatik Initiative",
  "content": "complete",
  "name": "MII_CS_Onko_Weitere_Klassifikationen_OBDS",
  "type": null,
  "experimental": "true",
  "resourceType": "CodeSystem",
  "title": "MII CodeSystem Onkologie - Weitere Klassifikationen oBDS",
  "package_version": "2026.0.0-ballot",
  "status": "active",
  "id": "9887adc1-3cfc-4dec-b205-ef7104d3fcab",
  "kind": null,
  "count": 181,
  "url": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/CodeSystem/mii-cs-onko-weitere-klassifikationen-obds",
  "concept": [ {
    "code": "binet",
    "concept": [ {
      "code": "binet-a",
      "display": "BINET A",
      "definition": "Early stage CLL: lymphocytosis in blood and bone marrow only"
    }, {
      "code": "binet-b",
      "display": "BINET B",
      "definition": "Intermediate stage CLL: lymphocytosis with enlarged lymph nodes or spleen/liver"
    }, {
      "code": "binet-c",
      "display": "BINET C",
      "definition": "Advanced stage CLL: lymphocytosis with anemia or thrombocytopenia"
    } ],
    "display": "BINET Staging System",
    "definition": "Staging system for chronic lymphocytic leukemia based on lymph node involvement and organ enlargement."
  }, {
    "code": "ann-arbor-stadium",
    "concept": [ {
      "code": "ann-arbor-i",
      "display": "I",
      "definition": "Single lymph node region or single extralymphatic organ"
    }, {
      "code": "ann-arbor-ia",
      "display": "IA",
      "definition": "Single lymph node region, asymptomatic"
    }, {
      "code": "ann-arbor-iae",
      "display": "IAE",
      "definition": "Single lymph node region with extranodal extension, asymptomatic"
    }, {
      "code": "ann-arbor-ib",
      "display": "IB",
      "definition": "Single lymph node region with B symptoms"
    }, {
      "code": "ann-arbor-ibe",
      "display": "IBE",
      "definition": "Single lymph node region with extranodal extension and B symptoms"
    }, {
      "code": "ann-arbor-ie",
      "display": "IE",
      "definition": "Single extralymphatic organ involvement"
    }, {
      "code": "ann-arbor-ix",
      "display": "IX",
      "definition": "Single lymph node region, symptoms unclear"
    }, {
      "code": "ann-arbor-ixa",
      "display": "IXA",
      "definition": "Single lymph node region, symptoms unclear, asymptomatic features"
    }, {
      "code": "ann-arbor-ixae",
      "display": "IXAE",
      "definition": "Single lymph node region with extranodal extension, symptoms unclear, asymptomatic features"
    }, {
      "code": "ann-arbor-ixb",
      "display": "IXB",
      "definition": "Single lymph node region, symptoms unclear, B symptom features"
    }, {
      "code": "ann-arbor-ixbe",
      "display": "IXBE",
      "definition": "Single lymph node region with extranodal extension, symptoms unclear, B symptom features"
    }, {
      "code": "ann-arbor-ixe",
      "display": "IXE",
      "definition": "Single extralymphatic organ, symptoms unclear"
    }, {
      "code": "ann-arbor-ii",
      "display": "II",
      "definition": "Two or more lymph node regions on same side of diaphragm"
    }, {
      "code": "ann-arbor-ii1",
      "display": "II1",
      "definition": "Two lymph node regions on same side of diaphragm"
    }, {
      "code": "ann-arbor-ii1a",
      "display": "II1A",
      "definition": "Two lymph node regions on same side of diaphragm, asymptomatic"
    }, {
      "code": "ann-arbor-ii1ae",
      "display": "II1AE",
      "definition": "Two lymph node regions on same side of diaphragm with extranodal extension, asymptomatic"
    }, {
      "code": "ann-arbor-ii1b",
      "display": "II1B",
      "definition": "Two lymph node regions on same side of diaphragm with B symptoms"
    }, {
      "code": "ann-arbor-ii1be",
      "display": "II1BE",
      "definition": "Two lymph node regions on same side of diaphragm with extranodal extension and B symptoms"
    }, {
      "code": "ann-arbor-ii1e",
      "display": "II1E",
      "definition": "Two lymph node regions on same side of diaphragm with extranodal extension"
    }, {
      "code": "ann-arbor-ii1x",
      "display": "II1X",
      "definition": "Two lymph node regions on same side of diaphragm, symptoms unclear"
    }, {
      "code": "ann-arbor-ii1xa",
      "display": "II1XA",
      "definition": "Two lymph node regions on same side of diaphragm, symptoms unclear, asymptomatic features"
    }, {
      "code": "ann-arbor-ii1xae",
      "display": "II1XAE",
      "definition": "Two lymph node regions on same side of diaphragm with extranodal extension, symptoms unclear, asymptomatic features"
    }, {
      "code": "ann-arbor-ii1xb",
      "display": "II1XB",
      "definition": "Two lymph node regions on same side of diaphragm, symptoms unclear, B symptom features"
    }, {
      "code": "ann-arbor-ii1xbe",
      "display": "II1XBE",
      "definition": "Two lymph node regions on same side of diaphragm with extranodal extension, symptoms unclear, B symptom features"
    }, {
      "code": "ann-arbor-ii1xe",
      "display": "II1XE",
      "definition": "Two lymph node regions on same side of diaphragm with extranodal extension, symptoms unclear"
    }, {
      "code": "ann-arbor-ii2",
      "display": "II2",
      "definition": "Multiple lymph node regions on same side of diaphragm"
    }, {
      "code": "ann-arbor-ii2a",
      "display": "II2A",
      "definition": "Multiple lymph node regions on same side of diaphragm, asymptomatic"
    }, {
      "code": "ann-arbor-ii2ae",
      "display": "II2AE",
      "definition": "Multiple lymph node regions on same side of diaphragm with extranodal extension, asymptomatic"
    }, {
      "code": "ann-arbor-ii2b",
      "display": "II2B",
      "definition": "Multiple lymph node regions on same side of diaphragm with B symptoms"
    }, {
      "code": "ann-arbor-ii2be",
      "display": "II2BE",
      "definition": "Multiple lymph node regions on same side of diaphragm with extranodal extension and B symptoms"
    }, {
      "code": "ann-arbor-ii2e",
      "display": "II2E",
      "definition": "Multiple lymph node regions on same side of diaphragm with extranodal extension"
    }, {
      "code": "ann-arbor-ii2x",
      "display": "II2X",
      "definition": "Multiple lymph node regions on same side of diaphragm, symptoms unclear"
    }, {
      "code": "ann-arbor-ii2xa",
      "display": "II2XA",
      "definition": "Multiple lymph node regions on same side of diaphragm, symptoms unclear, asymptomatic features"
    }, {
      "code": "ann-arbor-ii2xae",
      "display": "II2XAE",
      "definition": "Multiple lymph node regions on same side of diaphragm with extranodal extension, symptoms unclear, asymptomatic features"
    }, {
      "code": "ann-arbor-ii2xb",
      "display": "II2XB",
      "definition": "Multiple lymph node regions on same side of diaphragm, symptoms unclear, B symptom features"
    }, {
      "code": "ann-arbor-ii2xbe",
      "display": "II2XBE",
      "definition": "Multiple lymph node regions on same side of diaphragm with extranodal extension, symptoms unclear, B symptom features"
    }, {
      "code": "ann-arbor-ii2xe",
      "display": "II2XE",
      "definition": "Multiple lymph node regions on same side of diaphragm with extranodal extension, symptoms unclear"
    }, {
      "code": "ann-arbor-iia",
      "display": "IIA",
      "definition": "Two or more lymph node regions on same side of diaphragm, asymptomatic"
    }, {
      "code": "ann-arbor-iiae",
      "display": "IIAE",
      "definition": "Two or more lymph node regions on same side of diaphragm with extranodal extension, asymptomatic"
    }, {
      "code": "ann-arbor-iib",
      "display": "IIB",
      "definition": "Two or more lymph node regions on same side of diaphragm with B symptoms"
    }, {
      "code": "ann-arbor-iibe",
      "display": "IIBE",
      "definition": "Two or more lymph node regions on same side of diaphragm with extranodal extension and B symptoms"
    }, {
      "code": "ann-arbor-iie",
      "display": "IIE",
      "definition": "Two or more lymph node regions on same side of diaphragm with extranodal extension"
    }, {
      "code": "ann-arbor-iix",
      "display": "IIX",
      "definition": "Two or more lymph node regions on same side of diaphragm, symptoms unclear"
    }, {
      "code": "ann-arbor-iixa",
      "display": "IIXA",
      "definition": "Two or more lymph node regions on same side of diaphragm, symptoms unclear, asymptomatic features"
    }, {
      "code": "ann-arbor-iixae",
      "display": "IIXAE",
      "definition": "Two or more lymph node regions on same side of diaphragm with extranodal extension, symptoms unclear, asymptomatic features"
    }, {
      "code": "ann-arbor-iixb",
      "display": "IIXB",
      "definition": "Two or more lymph node regions on same side of diaphragm, symptoms unclear, B symptom features"
    }, {
      "code": "ann-arbor-iixbe",
      "display": "IIXBE",
      "definition": "Two or more lymph node regions on same side of diaphragm with extranodal extension, symptoms unclear, B symptom features"
    }, {
      "code": "ann-arbor-iixe",
      "display": "IIXE",
      "definition": "Two or more lymph node regions on same side of diaphragm with extranodal extension, symptoms unclear"
    }, {
      "code": "ann-arbor-iii",
      "display": "III",
      "definition": "Lymph node regions on both sides of diaphragm"
    }, {
      "code": "ann-arbor-iiia",
      "display": "IIIA",
      "definition": "Lymph node regions on both sides of diaphragm, asymptomatic"
    }, {
      "code": "ann-arbor-iiiae",
      "display": "IIIAE",
      "definition": "Lymph node regions on both sides of diaphragm with extranodal extension, asymptomatic"
    }, {
      "code": "ann-arbor-iiiaes",
      "display": "IIIAES",
      "definition": "Lymph node regions on both sides of diaphragm with extranodal extension and spleen involvement, asymptomatic"
    }, {
      "code": "ann-arbor-iiias",
      "display": "IIIAS",
      "definition": "Lymph node regions on both sides of diaphragm with spleen involvement, asymptomatic"
    }, {
      "code": "ann-arbor-iiib",
      "display": "IIIB",
      "definition": "Lymph node regions on both sides of diaphragm with B symptoms"
    }, {
      "code": "ann-arbor-iiibe",
      "display": "IIIBE",
      "definition": "Lymph node regions on both sides of diaphragm with extranodal extension and B symptoms"
    }, {
      "code": "ann-arbor-iiibes",
      "display": "IIIBES",
      "definition": "Lymph node regions on both sides of diaphragm with extranodal extension, spleen involvement, and B symptoms"
    }, {
      "code": "ann-arbor-iiibs",
      "display": "IIIBS",
      "definition": "Lymph node regions on both sides of diaphragm with spleen involvement and B symptoms"
    }, {
      "code": "ann-arbor-iiie",
      "display": "IIIE",
      "definition": "Lymph node regions on both sides of diaphragm with extranodal extension"
    }, {
      "code": "ann-arbor-iiies",
      "display": "IIIES",
      "definition": "Lymph node regions on both sides of diaphragm with extranodal extension and spleen involvement"
    }, {
      "code": "ann-arbor-iiis",
      "display": "IIIS",
      "definition": "Lymph node regions on both sides of diaphragm with spleen involvement"
    }, {
      "code": "ann-arbor-iiix",
      "display": "IIIX",
      "definition": "Lymph node regions on both sides of diaphragm, symptoms unclear"
    }, {
      "code": "ann-arbor-iiixa",
      "display": "IIIXA",
      "definition": "Lymph node regions on both sides of diaphragm, symptoms unclear, asymptomatic features"
    }, {
      "code": "ann-arbor-iiixae",
      "display": "IIIXAE",
      "definition": "Lymph node regions on both sides of diaphragm with extranodal extension, symptoms unclear, asymptomatic features"
    }, {
      "code": "ann-arbor-iiixaes",
      "display": "IIIXAES",
      "definition": "Lymph node regions on both sides of diaphragm with extranodal extension and spleen involvement, symptoms unclear, asymptomatic features"
    }, {
      "code": "ann-arbor-iiixas",
      "display": "IIIXAS",
      "definition": "Lymph node regions on both sides of diaphragm with spleen involvement, symptoms unclear, asymptomatic features"
    }, {
      "code": "ann-arbor-iiixb",
      "display": "IIIXB",
      "definition": "Lymph node regions on both sides of diaphragm, symptoms unclear, B symptom features"
    }, {
      "code": "ann-arbor-iiixbe",
      "display": "IIIXBE",
      "definition": "Lymph node regions on both sides of diaphragm with extranodal extension, symptoms unclear, B symptom features"
    }, {
      "code": "ann-arbor-iiixbes",
      "display": "IIIXBES",
      "definition": "Lymph node regions on both sides of diaphragm with extranodal extension and spleen involvement, symptoms unclear, B symptom features"
    }, {
      "code": "ann-arbor-iiixbs",
      "display": "IIIXBS",
      "definition": "Lymph node regions on both sides of diaphragm with spleen involvement, symptoms unclear, B symptom features"
    }, {
      "code": "ann-arbor-iiixe",
      "display": "IIIXE",
      "definition": "Lymph node regions on both sides of diaphragm with extranodal extension, symptoms unclear"
    }, {
      "code": "ann-arbor-iiixes",
      "display": "IIIXES",
      "definition": "Lymph node regions on both sides of diaphragm with extranodal extension and spleen involvement, symptoms unclear"
    }, {
      "code": "ann-arbor-iiixs",
      "display": "IIIXS",
      "definition": "Lymph node regions on both sides of diaphragm with spleen involvement, symptoms unclear"
    }, {
      "code": "ann-arbor-iii1",
      "display": "III1",
      "definition": "Limited lymph node regions on both sides of diaphragm"
    }, {
      "code": "ann-arbor-iii1a",
      "display": "III1A",
      "definition": "Limited lymph node regions on both sides of diaphragm, asymptomatic"
    }, {
      "code": "ann-arbor-iii1b",
      "display": "III1B",
      "definition": "Limited lymph node regions on both sides of diaphragm with B symptoms"
    }, {
      "code": "ann-arbor-iii2",
      "display": "III2",
      "definition": "Multiple lymph node regions on both sides of diaphragm"
    }, {
      "code": "ann-arbor-iii2a",
      "display": "III2A",
      "definition": "Multiple lymph node regions on both sides of diaphragm, asymptomatic"
    }, {
      "code": "ann-arbor-iii2b",
      "display": "III2B",
      "definition": "Multiple lymph node regions on both sides of diaphragm with B symptoms"
    }, {
      "code": "ann-arbor-iv",
      "display": "IV",
      "definition": "Disseminated involvement of one or more extralymphatic organs"
    }, {
      "code": "ann-arbor-iva",
      "display": "IVA",
      "definition": "Disseminated involvement of extralymphatic organs, asymptomatic"
    }, {
      "code": "ann-arbor-ivae",
      "display": "IVAE",
      "definition": "Disseminated involvement of extralymphatic organs with additional extranodal extension, asymptomatic"
    }, {
      "code": "ann-arbor-ivb",
      "display": "IVB",
      "definition": "Disseminated involvement of extralymphatic organs with B symptoms"
    }, {
      "code": "ann-arbor-ivbe",
      "display": "IVBE",
      "definition": "Disseminated involvement of extralymphatic organs with additional extranodal extension and B symptoms"
    }, {
      "code": "ann-arbor-ive",
      "display": "IVE",
      "definition": "Disseminated involvement of extralymphatic organs with extranodal extension"
    }, {
      "code": "ann-arbor-ivx",
      "display": "IVX",
      "definition": "Disseminated involvement of extralymphatic organs, symptoms unclear"
    }, {
      "code": "ann-arbor-ivxa",
      "display": "IVXA",
      "definition": "Disseminated involvement of extralymphatic organs, symptoms unclear, asymptomatic features"
    }, {
      "code": "ann-arbor-ivxae",
      "display": "IVXAE",
      "definition": "Disseminated involvement of extralymphatic organs with additional extranodal extension, symptoms unclear, asymptomatic features"
    }, {
      "code": "ann-arbor-ivxb",
      "display": "IVXB",
      "definition": "Disseminated involvement of extralymphatic organs, symptoms unclear, B symptom features"
    }, {
      "code": "ann-arbor-ivxbe",
      "display": "IVXBE",
      "definition": "Disseminated involvement of extralymphatic organs with additional extranodal extension, symptoms unclear, B symptom features"
    }, {
      "code": "ann-arbor-ivxe",
      "display": "IVXE",
      "definition": "Disseminated involvement of extralymphatic organs with extranodal extension, symptoms unclear"
    } ],
    "display": "Ann-Arbor Stadium",
    "definition": "Staging system for Hodgkin and Non-Hodgkin lymphomas based on anatomical extent of disease."
  }, {
    "code": "iss",
    "concept": [ {
      "code": "iss-i",
      "display": "ISS I",
      "definition": "Beta-2 microglobulin <3.5 mg/L and albumin ≥3.5 g/dL"
    }, {
      "code": "iss-ii",
      "display": "ISS II",
      "definition": "Not ISS I or ISS III"
    }, {
      "code": "iss-iii",
      "display": "ISS III",
      "definition": "Beta-2 microglobulin ≥5.5 mg/L"
    } ],
    "display": "International Staging System",
    "definition": "Staging system for multiple myeloma based on serum beta-2 microglobulin and albumin levels."
  }, {
    "code": "isswm",
    "concept": [ {
      "code": "isswm-n",
      "display": "ISSWM Niedrig",
      "definition": "Low risk: age ≤65 years, beta-2 microglobulin ≤3 mg/L, albumin >3.5 g/dL"
    }, {
      "code": "isswm-i",
      "display": "ISSWM Intermediär",
      "definition": "Intermediate risk: one adverse factor"
    }, {
      "code": "isswm-h",
      "display": "ISSWM Hoch",
      "definition": "High risk: age >65 years or beta-2 microglobulin >3 mg/L, or albumin ≤3.5 g/dL (≥2 factors)"
    } ],
    "display": "International Scoring System for Waldenström's Macroglobulinemia",
    "definition": "Prognostic scoring system for Waldenström's macroglobulinemia based on age, beta-2 microglobulin, and albumin levels."
  }, {
    "code": "who-grad",
    "concept": [ {
      "code": "who-grad-i",
      "display": "WHO Grad I",
      "definition": "Well-differentiated, slow-growing, low proliferative potential"
    }, {
      "code": "who-grad-ii",
      "display": "WHO Grad II",
      "definition": "Moderately differentiated, infiltrative, low proliferative potential"
    }, {
      "code": "who-grad-iii",
      "display": "WHO Grad III",
      "definition": "Poorly differentiated, anaplastic, high proliferative potential"
    }, {
      "code": "who-grad-iv",
      "display": "WHO Grad IV",
      "definition": "Poorly differentiated, high mitotic activity, necrosis, microvascular proliferation"
    } ],
    "display": "WHO Grade",
    "definition": "World Health Organization grading system for central nervous system tumors based on histological features."
  }, {
    "code": "formen",
    "concept": [ {
      "code": "formen-k",
      "display": "Klassisch",
      "definition": "Classical form of lymphoma presentation"
    }, {
      "code": "formen-v",
      "display": "Variante",
      "definition": "Variant form of lymphoma presentation"
    } ],
    "display": "Formen",
    "definition": "Classification of lymphoma forms distinguishing classical and variant presentations."
  }, {
    "code": "eln-klassifikation",
    "concept": [ {
      "code": "eln-g",
      "display": "ELN Günstig",
      "definition": "Favorable risk: good prognosis cytogenetic/molecular markers"
    }, {
      "code": "eln-i1",
      "display": "ELN Intermediär I",
      "definition": "Intermediate risk I: intermediate prognosis markers"
    }, {
      "code": "eln-i2",
      "display": "ELN Intermediär II",
      "definition": "Intermediate risk II: intermediate prognosis markers"
    }, {
      "code": "eln-u",
      "display": "ELN Ungünstig",
      "definition": "Unfavorable risk: poor prognosis cytogenetic/molecular markers"
    }, {
      "code": "eln-cp",
      "display": "ELN Chronische Phase",
      "definition": "Chronic phase (CML context)"
    }, {
      "code": "eln-ap",
      "display": "ELN Akzelierte Phase",
      "definition": "Accelerated phase (CML context)"
    }, {
      "code": "eln-bk",
      "display": "ELN Blastenkrise",
      "definition": "Blast crisis phase (CML context)"
    } ],
    "display": "ELN-Klassifikation",
    "definition": "European LeukemiaNet risk stratification for acute myeloid leukemia based on cytogenetic and molecular genetic abnormalities."
  }, {
    "code": "durie-salmon-stadium",
    "concept": [ {
      "code": "durie-salmon-i",
      "display": "Durie-Salmon I",
      "definition": "Low tumor burden: hemoglobin >10 g/dL, calcium normal, no bone lesions"
    }, {
      "code": "durie-salmon-ia",
      "display": "Durie-Salmon IA",
      "definition": "Low tumor burden with normal renal function"
    }, {
      "code": "durie-salmon-ib",
      "display": "Durie-Salmon IB",
      "definition": "Low tumor burden with abnormal renal function"
    }, {
      "code": "durie-salmon-ii",
      "display": "Durie-Salmon II",
      "definition": "Intermediate tumor burden: neither stage I nor III criteria"
    }, {
      "code": "durie-salmon-iia",
      "display": "Durie-Salmon IIA",
      "definition": "Intermediate tumor burden with normal renal function"
    }, {
      "code": "durie-salmon-iib",
      "display": "Durie-Salmon IIB",
      "definition": "Intermediate tumor burden with abnormal renal function"
    }, {
      "code": "durie-salmon-iii",
      "display": "Durie-Salmon III",
      "definition": "High tumor burden: hemoglobin <8.5 g/dL, calcium elevated, extensive bone lesions"
    }, {
      "code": "durie-salmon-iiia",
      "display": "Durie-Salmon IIIA",
      "definition": "High tumor burden with normal renal function"
    }, {
      "code": "durie-salmon-iiib",
      "display": "Durie-Salmon IIIB",
      "definition": "High tumor burden with abnormal renal function"
    } ],
    "display": "Durie-Salmon Stadium",
    "definition": "Multiple myeloma staging system based on tumor burden and organ function."
  }, {
    "code": "bismuth",
    "concept": [ {
      "code": "bismuth-i",
      "display": "Bismuth I",
      "definition": "Tumor below confluence of left and right hepatic ducts"
    }, {
      "code": "bismuth-ii",
      "display": "Bismuth II",
      "definition": "Tumor reaching confluence but not involving secondary ducts"
    }, {
      "code": "bismuth-iii",
      "display": "Bismuth III",
      "definition": "Tumor involving confluence and either right or left secondary ducts"
    }, {
      "code": "bismuth-iiia",
      "display": "Bismuth IIIA",
      "definition": "Tumor involving confluence and right secondary ducts"
    }, {
      "code": "bismuth-iiib",
      "display": "Bismuth IIIB",
      "definition": "Tumor involving confluence and left secondary ducts"
    }, {
      "code": "bismuth-iv",
      "display": "Bismuth IV",
      "definition": "Tumor involving confluence and both right and left secondary ducts"
    } ],
    "display": "Bismuth",
    "definition": "Classification system for hilar cholangiocarcinoma based on the extent of biliary involvement and resectability."
  }, {
    "code": "masaoka",
    "concept": [ {
      "code": "masaoka-i",
      "display": "Masaoka I",
      "definition": "Encapsulated tumor without invasion"
    }, {
      "code": "masaoka-ii",
      "display": "Masaoka II",
      "definition": "Invasion into surrounding fatty tissue or mediastinal pleura"
    }, {
      "code": "masaoka-iii",
      "display": "Masaoka III",
      "definition": "Invasion into neighboring organs"
    }, {
      "code": "masaoka-iv",
      "display": "Masaoka IV",
      "definition": "Pleural or pericardial dissemination"
    }, {
      "code": "masaoka-iva",
      "display": "Masaoka IVA",
      "definition": "Pleural or pericardial implants"
    }, {
      "code": "masaoka-ivb",
      "display": "Masaoka IVB",
      "definition": "Lymphogenous or hematogenous metastasis"
    } ],
    "display": "Masaoka",
    "definition": "Staging system for thymomas based on invasiveness and extent of disease."
  }, {
    "code": "mitoserate-gist",
    "concept": [ {
      "code": "mitoserate-gist-n",
      "display": "Mitoserate-GIST Niedrig",
      "definition": "Low mitotic rate: ≤5 mitoses per 50 HPF"
    }, {
      "code": "mitoserate-gist-h",
      "display": "Mitoserate-GIST Hoch",
      "definition": "High mitotic rate: >5 mitoses per 50 HPF"
    } ],
    "display": "Mitoserate-GIST",
    "definition": "Mitotic rate assessment for gastrointestinal stromal tumors."
  }, {
    "code": "p16",
    "concept": [ {
      "code": "p16-p",
      "display": "p16 Positiv",
      "definition": "Positive p16 protein expression"
    }, {
      "code": "p16-n",
      "display": "p16 Negativ",
      "definition": "Negative p16 protein expression"
    } ],
    "display": "p16",
    "definition": "p16 protein expression status assessment."
  }, {
    "code": "eutos-score",
    "concept": [ {
      "code": "eutos-score-n",
      "display": "EUTOS-Score Niedrigrisiko",
      "definition": "Low risk EUTOS score: ≤87"
    }, {
      "code": "eutos-score-h",
      "display": "EUTOS-Score Hochrisiko",
      "definition": "High risk EUTOS score: >87"
    } ],
    "display": "EUTOS-Score",
    "definition": "European Treatment and Outcome Study prognostic score for chronic myeloid leukemia."
  }, {
    "code": "sanz-score",
    "concept": [ {
      "code": "sanz-score-n",
      "display": "Sanz-Score Niedrig",
      "definition": "Low risk: WBC <10x10⁹/L and platelets >40x10⁹/L"
    }, {
      "code": "sanz-score-i",
      "display": "Sanz-Score Intermediär",
      "definition": "Intermediate risk: WBC <10x10⁹/L and platelets ≤40x10⁹/L"
    }, {
      "code": "sanz-score-h",
      "display": "Sanz-Score Hoch",
      "definition": "High risk: WBC ≥10x10⁹/L"
    } ],
    "display": "Sanz-Score",
    "definition": "Risk assessment score for acute promyelocytic leukemia."
  }, {
    "code": "ipi",
    "concept": [ {
      "code": "ipi-n",
      "display": "IPI Niedrig",
      "definition": "Low risk: 0-1 risk factors"
    }, {
      "code": "ipi-ni",
      "display": "IPI Niedrig-Intermediär",
      "definition": "Low-intermediate risk: 2 risk factors"
    }, {
      "code": "ipi-hi",
      "display": "IPI Hoch-Intermediär",
      "definition": "High-intermediate risk: 3 risk factors"
    }, {
      "code": "ipi-h",
      "display": "IPI Hoch",
      "definition": "High risk: 4-5 risk factors"
    } ],
    "display": "IPI",
    "definition": "International Prognostic Index for aggressive non-Hodgkin lymphoma."
  }, {
    "code": "flipi",
    "concept": [ {
      "code": "flipi-l",
      "display": "FLIPI Low risk",
      "definition": "Low risk: 0-1 risk factors"
    }, {
      "code": "flipi-i",
      "display": "FLIPI Intermediate risk",
      "definition": "Intermediate risk: 2 risk factors"
    }, {
      "code": "flipi-h",
      "display": "FLIPI High risk",
      "definition": "High risk: ≥3 risk factors"
    } ],
    "display": "FLIPI",
    "definition": "Follicular Lymphoma International Prognostic Index."
  }, {
    "code": "mipi",
    "concept": [ {
      "code": "mipi-n",
      "display": "MIPI Niedrig",
      "definition": "Low risk MIPI score"
    }, {
      "code": "mipi-i",
      "display": "MIPI Intermediär",
      "definition": "Intermediate risk MIPI score"
    }, {
      "code": "mipi-h",
      "display": "MIPI Hoch",
      "definition": "High risk MIPI score"
    } ],
    "display": "MIPI",
    "definition": "Mantle Cell Lymphoma International Prognostic Index."
  }, {
    "code": "risikogruppen-ghsg",
    "concept": [ {
      "code": "risikogruppen-ghsg-fr",
      "display": "GHSG Frühe",
      "definition": "Early favorable risk group"
    }, {
      "code": "risikogruppen-ghsg-i",
      "display": "GHSG Intermediär",
      "definition": "Intermediate risk group"
    }, {
      "code": "risikogruppen-ghsg-fo",
      "display": "GHSG Fortgeschritten",
      "definition": "Advanced risk group"
    } ],
    "display": "Risikogruppen GHSG",
    "definition": "German Hodgkin Study Group risk stratification."
  }, {
    "code": "ipss",
    "concept": [ {
      "code": "ipss-l",
      "display": "IPSS Low",
      "definition": "Low risk: score 0"
    }, {
      "code": "ipss-i1",
      "display": "IPSS Intermediate-I",
      "definition": "Intermediate-1 risk: score 0.5-1.0"
    }, {
      "code": "ipss-i2",
      "display": "IPSS Intermediate-II",
      "definition": "Intermediate-2 risk: score 1.5-2.0"
    }, {
      "code": "ipss-h",
      "display": "IPSS High risk",
      "definition": "High risk: score ≥2.5"
    } ],
    "display": "IPSS",
    "definition": "International Prognostic Scoring System for myelodysplastic syndromes."
  }, {
    "code": "her2-neu",
    "concept": [ {
      "code": "her2-neu-p",
      "display": "HER2-neu Positiv",
      "definition": "Positive HER2-neu status (IHC 3+ or FISH amplified)"
    }, {
      "code": "her2-neu-n",
      "display": "HER2-neu Negativ",
      "definition": "Negative HER2-neu status (IHC 0-1+ or FISH not amplified)"
    } ],
    "display": "HER2-neu",
    "definition": "HER2-neu protein expression and gene amplification status."
  } ],
  "version": "2026.0.0-ballot",
  "contact": [ {
    "telecom": [ {
      "value": "https://www.medizininformatik-initiative.de",
      "system": "url"
    } ]
  } ]
}