description: For cancer related trials, severity is represented as a grade. Describes the grade of the adverse event, in relation to the subject not the resulting condition. In the context of clinical research, it is the investigator’s assessment of severity, in oncology related trials this is reported as grade. package_name: hl7.fhir.uv.ae derivation: constraint name: AdverseEventGrade type: Extension elements: extension: {index: 0} url: pattern: {type: Uri, value: 'http://hl7.org/fhir/uv/ae-research-ig/StructureDefinition/ae-grade'} index: 1 value: choices: [valueCodeableConcept] index: 3 valueCodeableConcept: {type: CodeableConcept, choiceOf: value, index: 4} package_version: research-ig-1.0.0 extensions: {} class: extension kind: complex-type url: http://hl7.org/fhir/uv/ae-research-ig/StructureDefinition/ae-grade base: http://hl7.org/fhir/StructureDefinition/Extension version: 1.0.0