description: Profile with properties for observations that convey the potential impact of genomic characteristics on a medication or non-medicinal therapy.
package_name: hl7.fhir.uv.genomics-reporting
derivation: constraint
name: TherapeuticImplication
type: Observation
elements:
  code:
    short: therapeutic-implication
    pattern:
      type: CodeableConcept
      value:
        coding:
        - {code: therapeutic-implication, system: 'http://hl7.org/fhir/uv/genomics-reporting/CodeSystem/tbd-codes-cs'}
    index: 0
  component:
    short: Therapeutic Implication
    array: true
    index: 1
    slicing:
      slices:
        therapeutic-implication:
          match: {}
          schema:
            short: Therapeutic Implication
            array: true
            index: 1
            extensions:
              related-artifact: {url: null, index: 2}
            elements:
              extension:
                index: 2
                slicing:
                  slices:
                    related-artifact:
                      match: {}
                      schema: {index: 2}
              code:
                short: therapeutic-implication
                pattern:
                  type: CodeableConcept
                  value:
                    coding:
                    - {code: therapeutic-implication, system: 'http://hl7.org/fhir/uv/genomics-reporting/CodeSystem/tbd-codes-cs'}
                index: 3
              value:
                short: Responsive | Resistant | Poor metabolizer | Rapid metabolizer | Decreased function | Increased function | Does not meet eligibility criteria for clinical trial | ... (more)
                choices: [valueCodeableConcept]
                index: 5
              valueCodeableConcept: {type: CodeableConcept, short: Responsive | Resistant | Poor metabolizer | Rapid metabolizer | Decreased function | Increased function | Does not meet eligibility criteria for clinical trial | ... (more), choiceOf: value, index: 6}
            required: [value, valueCodeableConcept]
        phenotypic-treatment-context:
          match: {}
          schema:
            short: Phenotypic treatment context
            array: true
            index: 7
            extensions:
              related-artifact: {url: null, index: 8}
            elements:
              extension:
                index: 8
                slicing:
                  slices:
                    related-artifact:
                      match: {}
                      schema: {index: 8}
              code:
                short: 81259-4
                pattern:
                  type: CodeableConcept
                  value:
                    coding:
                    - {code: 81259-4, system: 'http://loinc.org'}
                index: 9
              value:
                short: Contextual phenotype/condition code
                choices: [valueCodeableConcept]
                index: 11
              valueCodeableConcept: {type: CodeableConcept, short: Contextual phenotype/condition code, choiceOf: value, index: 12}
            required: [value, valueCodeableConcept]
        medication-assessed:
          match: {}
          schema:
            short: Medication Assessed
            array: true
            index: 13
            extensions:
              related-artifact: {url: null, index: 14}
              medication-assessed-reference: {url: 'http://hl7.org/fhir/uv/genomics-reporting/StructureDefinition/medication-assessed-reference', min: 0, type: Extension, index: 15}
            elements:
              extension:
                index: 14
                slicing:
                  slices:
                    related-artifact:
                      match: {}
                      schema: {index: 14}
                    medication-assessed-reference:
                      match: {}
                      schema: {type: Extension, url: 'http://hl7.org/fhir/uv/genomics-reporting/StructureDefinition/medication-assessed-reference', index: 15}
                      min: 0
              code:
                short: 51963-7
                pattern:
                  type: CodeableConcept
                  value:
                    coding:
                    - {code: 51963-7, system: 'http://loinc.org'}
                index: 16
              value:
                short: Medication code
                choices: [valueCodeableConcept]
                index: 18
              valueCodeableConcept: {type: CodeableConcept, short: Medication code, choiceOf: value, index: 19}
            required: [value, valueCodeableConcept]
        therapy-assessed:
          match: {}
          schema:
            short: Non-medication therapy assessed
            array: true
            index: 20
            extensions:
              related-artifact: {url: null, index: 21}
              therapy-assessed-reference: {url: 'http://hl7.org/fhir/uv/genomics-reporting/StructureDefinition/therapy-assessed-reference', min: 0, type: Extension, index: 22}
            elements:
              extension:
                index: 21
                slicing:
                  slices:
                    related-artifact:
                      match: {}
                      schema: {index: 21}
                    therapy-assessed-reference:
                      match: {}
                      schema: {type: Extension, url: 'http://hl7.org/fhir/uv/genomics-reporting/StructureDefinition/therapy-assessed-reference', index: 22}
                      min: 0
              code:
                short: associated-therapy
                pattern:
                  type: CodeableConcept
                  value:
                    coding:
                    - {code: associated-therapy, system: 'http://hl7.org/fhir/uv/genomics-reporting/CodeSystem/tbd-codes-cs'}
                index: 23
              value:
                choices: [valueCodeableConcept]
                index: 25
              valueCodeableConcept: {type: CodeableConcept, choiceOf: value, index: 26}
            required: [value, valueCodeableConcept]
package_version: 3.0.0-ballot
class: profile
kind: resource
url: http://hl7.org/fhir/uv/genomics-reporting/StructureDefinition/therapeutic-implication
base: http://hl7.org/fhir/uv/genomics-reporting/StructureDefinition/implication
version: 3.0.0-ballot