{
  "description": "Target enrichment protocol for whole exome sequencing covering 35.8 Mb of the human exome",
  "_filename": "example/PlanDefinition-mii-exa-molgen-protocol-agilent-sureselect.json",
  "package_name": "de.medizininformatikinitiative.kerndatensatz.molgen",
  "date": "2026-09-13T11:07:11+00:00",
  "publisher": "Medizininformatik-Initiative",
  "jurisdiction": [ {
    "coding": [ {
      "code": "DE",
      "system": "urn:iso:std:iso:3166",
      "display": "Germany"
    } ]
  } ],
  "name": "AgilentSureSelectV7",
  "type": "{:coding [{:system \\\"http://terminology.hl7.org/CodeSystem/plan-definition-type\\\", :code \\\"protocol\\\", :display \\\"Protocol\\\"}]}",
  "experimental": null,
  "resourceType": "PlanDefinition",
  "title": "Agilent SureSelect Human All Exon V7 Kit Protocol",
  "package_version": "2027.0.0-ballot",
  "status": "active",
  "id": "7f94f14a-4b16-4a6a-8c77-38aa802fad01",
  "kind": null,
  "url": "https://www.medizininformatik-initiative.de/fhir/ext/modul-molgen/PlanDefinition/mii-exa-molgen-protocol-agilent-sureselect",
  "action": [ {
    "title": "DNA Fragmentation",
    "description": "Fragment genomic DNA to 150-200bp using Covaris"
  }, {
    "title": "Library Preparation",
    "description": "End repair, A-tailing, adapter ligation"
  }, {
    "title": "Hybridization",
    "description": "Hybridize with SureSelect baits for 24 hours at 65°C"
  }, {
    "title": "Capture",
    "description": "Streptavidin bead capture and washing"
  }, {
    "title": "Amplification",
    "description": "PCR amplification of captured library"
  } ],
  "version": "2027.0.0-ballot",
  "contact": [ {
    "name": "Medizininformatik-Initiative",
    "telecom": [ {
      "value": "https://www.medizininformatik-initiative.de/",
      "system": "url"
    }, {
      "value": "info@medizininformatik-initiative.de",
      "system": "email"
    } ]
  } ]
}