{
"description": "MII LogicalModel Modellvorhaben Genomsequenzierung Onkologie",
"_filename": "StructureDefinition-mii-lm-mvgenomseq-onkologie.json",
"package_name": "de.medizininformatikinitiative.kerndatensatz.onkologie",
"date": null,
"derivation": "specialization",
"publisher": "Medizininformatik Initiative",
"fhirVersion": "4.0.1",
"name": "MII_LM_MVGenomSeq_Onkologie",
"mapping": [ {
"name": "Onkologie LogicalModel MII Onkologie Mapping",
"identity": "MVGenomSeq-Datenkranz-to-MII-FHIR"
} ],
"abstract": false,
"type": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onkologie/StructureDefinition/LogicalModel/mii-lm-mvgenomseq-onkologie",
"experimental": null,
"resourceType": "StructureDefinition",
"title": "MII LM Modellvorhaben Genomsequenzierung Onkologie",
"package_version": "2025.0.4",
"snapshot": {
"element": [ {
"constraint": [ {
"key": "ele-1",
"human": "All FHIR elements must have a @value or children",
"xpath": "@value|f:*|h:div",
"severity": "error",
"expression": "hasValue() or (children().count() > id.count())"
} ],
"path": "mii-lm-mvgenomseq-onkologie",
"min": 0,
"definition": "MII LogicalModel Modellvorhaben Genomsequenzierung Onkologie",
"isModifier": false,
"short": "MII LM Modellvorhaben Genomsequenzierung Onkologie",
"mapping": [ {
"map": "n/a",
"identity": "rim"
} ],
"extension": [ {
"url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status",
"valueCode": "normative"
}, {
"url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-normative-version",
"valueCode": "4.0.0"
} ],
"max": "*",
"id": "mii-lm-mvgenomseq-onkologie",
"condition": [ "ele-1" ],
"base": {
"max": "*",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie"
}
}, {
"path": "mii-lm-mvgenomseq-onkologie.id",
"min": 0,
"definition": "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
"isModifier": false,
"short": "Unique id for inter-element referencing",
"mapping": [ {
"map": "n/a",
"identity": "rim"
} ],
"type": [ {
"code": "http://hl7.org/fhirpath/System.String",
"extension": [ {
"url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
"valueUrl": "string"
} ]
} ],
"representation": [ "xmlAttr" ],
"max": "1",
"id": "mii-lm-mvgenomseq-onkologie.id",
"base": {
"max": "1",
"min": 0,
"path": "Element.id"
},
"isSummary": false
}, {
"constraint": [ {
"key": "ele-1",
"human": "All FHIR elements must have a @value or children",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element",
"severity": "error",
"expression": "hasValue() or (children().count() > id.count())"
}, {
"key": "ext-1",
"human": "Must have either extensions or value[x], not both",
"xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
"source": "http://hl7.org/fhir/StructureDefinition/Extension",
"severity": "error",
"expression": "extension.exists() != value.exists()"
} ],
"path": "mii-lm-mvgenomseq-onkologie.extension",
"min": 0,
"definition": "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
"isModifier": false,
"short": "Additional content defined by implementations",
"mapping": [ {
"map": "n/a",
"identity": "rim"
} ],
"slicing": {
"rules": "open",
"description": "Extensions are always sliced by (at least) url",
"discriminator": [ {
"path": "url",
"type": "value"
} ]
},
"type": [ {
"code": "Extension"
} ],
"alias": [ "extensions", "user content" ],
"max": "*",
"id": "mii-lm-mvgenomseq-onkologie.extension",
"comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
"base": {
"max": "*",
"min": 0,
"path": "Element.extension"
},
"isSummary": false
}, {
"constraint": [ {
"key": "ele-1",
"human": "All FHIR elements must have a @value or children",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element",
"severity": "error",
"expression": "hasValue() or (children().count() > id.count())"
} ],
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall",
"min": 0,
"definition": "Onkologie-Fall",
"isModifier": false,
"short": "Onkologie-Fall",
"mapping": [ {
"map": "n/a",
"identity": "rim"
} ],
"type": [ {
"code": "BackboneElement"
} ],
"extension": [ {
"url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status",
"valueCode": "normative"
}, {
"url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-normative-version",
"valueCode": "4.0.0"
} ],
"max": "*",
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFall",
"condition": [ "ele-1" ],
"base": {
"max": "*",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall"
}
}, {
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.id",
"min": 0,
"definition": "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
"isModifier": false,
"short": "Unique id for inter-element referencing",
"mapping": [ {
"map": "n/a",
"identity": "rim"
} ],
"type": [ {
"code": "http://hl7.org/fhirpath/System.String",
"extension": [ {
"url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
"valueUrl": "string"
} ]
} ],
"representation": [ "xmlAttr" ],
"max": "1",
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFall.id",
"base": {
"max": "1",
"min": 0,
"path": "Element.id"
},
"isSummary": false
}, {
"constraint": [ {
"key": "ele-1",
"human": "All FHIR elements must have a @value or children",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element",
"severity": "error",
"expression": "hasValue() or (children().count() > id.count())"
}, {
"key": "ext-1",
"human": "Must have either extensions or value[x], not both",
"xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
"source": "http://hl7.org/fhir/StructureDefinition/Extension",
"severity": "error",
"expression": "extension.exists() != value.exists()"
} ],
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.extension",
"min": 0,
"definition": "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
"isModifier": false,
"short": "Additional content defined by implementations",
"mapping": [ {
"map": "n/a",
"identity": "rim"
} ],
"slicing": {
"rules": "open",
"description": "Extensions are always sliced by (at least) url",
"discriminator": [ {
"path": "url",
"type": "value"
} ]
},
"type": [ {
"code": "Extension"
} ],
"alias": [ "extensions", "user content" ],
"max": "*",
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFall.extension",
"comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
"base": {
"max": "*",
"min": 0,
"path": "Element.extension"
},
"isSummary": false
}, {
"constraint": [ {
"key": "ele-1",
"human": "All FHIR elements must have a @value or children",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element",
"severity": "error",
"expression": "hasValue() or (children().count() > id.count())"
}, {
"key": "ext-1",
"human": "Must have either extensions or value[x], not both",
"xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
"source": "http://hl7.org/fhir/StructureDefinition/Extension",
"severity": "error",
"expression": "extension.exists() != value.exists()"
} ],
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.modifierExtension",
"requirements": "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](extensibility.html#modifierExtension).",
"min": 0,
"definition": "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).",
"isModifier": true,
"short": "Extensions that cannot be ignored even if unrecognized",
"mapping": [ {
"map": "N/A",
"identity": "rim"
} ],
"type": [ {
"code": "Extension"
} ],
"alias": [ "extensions", "user content", "modifiers" ],
"max": "*",
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFall.modifierExtension",
"comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
"base": {
"max": "*",
"min": 0,
"path": "BackboneElement.modifierExtension"
},
"isModifierReason": "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them",
"isSummary": true
}, {
"constraint": [ {
"key": "ele-1",
"human": "All FHIR elements must have a @value or children",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element",
"severity": "error",
"expression": "hasValue() or (children().count() > id.count())"
} ],
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Diagnose",
"min": 1,
"definition": "Diagnose",
"isModifier": false,
"short": "Diagnose",
"mapping": [ {
"map": "n/a",
"identity": "rim"
}, {
"map": "Condition",
"identity": "MVGenomSeq-Datenkranz-to-MII-FHIR"
} ],
"type": [ {
"code": "BackboneElement"
} ],
"extension": [ {
"url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status",
"valueCode": "normative"
}, {
"url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-normative-version",
"valueCode": "4.0.0"
} ],
"max": "1",
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Diagnose",
"condition": [ "ele-1" ],
"base": {
"max": "1",
"min": 1,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Diagnose"
}
}, {
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Diagnose.id",
"min": 0,
"definition": "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
"isModifier": false,
"short": "Unique id for inter-element referencing",
"mapping": [ {
"map": "n/a",
"identity": "rim"
} ],
"type": [ {
"code": "http://hl7.org/fhirpath/System.String",
"extension": [ {
"url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
"valueUrl": "string"
} ]
} ],
"representation": [ "xmlAttr" ],
"max": "1",
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Diagnose.id",
"base": {
"max": "1",
"min": 0,
"path": "Element.id"
},
"isSummary": false
}, {
"constraint": [ {
"key": "ele-1",
"human": "All FHIR elements must have a @value or children",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element",
"severity": "error",
"expression": "hasValue() or (children().count() > id.count())"
}, {
"key": "ext-1",
"human": "Must have either extensions or value[x], not both",
"xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
"source": "http://hl7.org/fhir/StructureDefinition/Extension",
"severity": "error",
"expression": "extension.exists() != value.exists()"
} ],
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Diagnose.extension",
"min": 0,
"definition": "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
"isModifier": false,
"short": "Additional content defined by implementations",
"mapping": [ {
"map": "n/a",
"identity": "rim"
} ],
"slicing": {
"rules": "open",
"description": "Extensions are always sliced by (at least) url",
"discriminator": [ {
"path": "url",
"type": "value"
} ]
},
"type": [ {
"code": "Extension"
} ],
"alias": [ "extensions", "user content" ],
"max": "*",
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Diagnose.extension",
"comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
"base": {
"max": "*",
"min": 0,
"path": "Element.extension"
},
"isSummary": false
}, {
"constraint": [ {
"key": "ele-1",
"human": "All FHIR elements must have a @value or children",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element",
"severity": "error",
"expression": "hasValue() or (children().count() > id.count())"
}, {
"key": "ext-1",
"human": "Must have either extensions or value[x], not both",
"xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
"source": "http://hl7.org/fhir/StructureDefinition/Extension",
"severity": "error",
"expression": "extension.exists() != value.exists()"
} ],
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Diagnose.modifierExtension",
"requirements": "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](extensibility.html#modifierExtension).",
"min": 0,
"definition": "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).",
"isModifier": true,
"short": "Extensions that cannot be ignored even if unrecognized",
"mapping": [ {
"map": "N/A",
"identity": "rim"
} ],
"type": [ {
"code": "Extension"
} ],
"alias": [ "extensions", "user content", "modifiers" ],
"max": "*",
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Diagnose.modifierExtension",
"comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
"base": {
"max": "*",
"min": 0,
"path": "BackboneElement.modifierExtension"
},
"isModifierReason": "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them",
"isSummary": true
}, {
"constraint": [ {
"key": "ele-1",
"human": "All FHIR elements must have a @value or children",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element",
"severity": "error",
"expression": "hasValue() or (children().count() > id.count())"
} ],
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Diagnose.Haupttumordiagnose",
"min": 1,
"definition": "Haupttumordiagnose in ICD-10-GM",
"isModifier": false,
"short": "Haupttumordiagnose",
"mapping": [ {
"map": "Condition.code.coding.where(system='http://fhir.de/CodeSystem/bfarm/icd-10-gm').code",
"identity": "MVGenomSeq-Datenkranz-to-MII-FHIR"
} ],
"type": [ {
"code": "code"
} ],
"max": "1",
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Diagnose.Haupttumordiagnose",
"base": {
"max": "1",
"min": 1,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Diagnose.Haupttumordiagnose"
},
"isSummary": false
}, {
"constraint": [ {
"key": "ele-1",
"human": "All FHIR elements must have a @value or children",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element",
"severity": "error",
"expression": "hasValue() or (children().count() > id.count())"
} ],
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Diagnose.WeitereOnkologischeDiagnosen",
"min": 0,
"definition": "Optional bei mehreren onkologischen Diagnosen, insbesondere Dokumentation als weiter onkologische Diagnose bei hereditären Tumordispositionssydroms (HT), bei HT zusätzliche Dokumentation ORPHAcode oder AlphaID, ein Code soweit vorhanden ist. Undiagnostizierte Erkrankungen sind mit ORPHA:616874 zu kodieren.",
"isModifier": false,
"short": "Weitere onkologische Diagnosen",
"mapping": [ {
"map": "Condition.code.coding.where(system='http://fhir.de/CodeSystem/bfarm/icd-10-gm').code",
"identity": "MVGenomSeq-Datenkranz-to-MII-FHIR"
} ],
"type": [ {
"code": "code"
} ],
"max": "*",
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Diagnose.WeitereOnkologischeDiagnosen",
"base": {
"max": "*",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Diagnose.WeitereOnkologischeDiagnosen"
},
"isSummary": false
}, {
"constraint": [ {
"key": "ele-1",
"human": "All FHIR elements must have a @value or children",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element",
"severity": "error",
"expression": "hasValue() or (children().count() > id.count())"
} ],
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Diagnose.Hauptdiagnosedatum",
"min": 0,
"definition": "Datum der Erstdiagnose der Hauptdiagnose. Wenn Tag unbekannt -> 15. des Monats",
"isModifier": false,
"short": "Hauptdiagnosedatum",
"mapping": [ {
"map": "Condition.extension.where(url='http://hl7.org/fhir/StructureDefinition/condition-assertedDate').valueDate",
"identity": "MVGenomSeq-Datenkranz-to-MII-FHIR"
} ],
"type": [ {
"code": "date"
} ],
"max": "1",
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Diagnose.Hauptdiagnosedatum",
"base": {
"max": "1",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Diagnose.Hauptdiagnosedatum"
},
"isSummary": false
}, {
"constraint": [ {
"key": "ele-1",
"human": "All FHIR elements must have a @value or children",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element",
"severity": "error",
"expression": "hasValue() or (children().count() > id.count())"
} ],
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Diagnose.ECOGStatus",
"min": 0,
"definition": "Eastern Cooperative Oncology Group (ECOG) Performance Status nach 0,1,2,3,4,5,unknown, not applicable",
"isModifier": false,
"short": "ECOG-Status",
"mapping": [ {
"map": "Observation.where(code='423740007' and system='http://snomed.info/sct').valueCodeableConcept.coding.code",
"identity": "MVGenomSeq-Datenkranz-to-MII-FHIR"
} ],
"type": [ {
"code": "code"
} ],
"max": "1",
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Diagnose.ECOGStatus",
"base": {
"max": "1",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Diagnose.ECOGStatus"
},
"isSummary": false
}, {
"constraint": [ {
"key": "ele-1",
"human": "All FHIR elements must have a @value or children",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element",
"severity": "error",
"expression": "hasValue() or (children().count() > id.count())"
} ],
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Diagnose.KeimbahndiagnoseVorhanden",
"min": 0,
"definition": "Ja, Nein, unbekannt",
"isModifier": false,
"short": "Keimbahndiagnose vorhanden",
"mapping": [ {
"map": "no direct match, vsl. über FHIRPath automatisch generieren, wenn Keimbahndiagnose.exists()",
"identity": "MVGenomSeq-Datenkranz-to-MII-FHIR"
} ],
"type": [ {
"code": "code"
} ],
"max": "1",
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Diagnose.KeimbahndiagnoseVorhanden",
"base": {
"max": "1",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Diagnose.KeimbahndiagnoseVorhanden"
},
"isSummary": false
}, {
"constraint": [ {
"key": "ele-1",
"human": "All FHIR elements must have a @value or children",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element",
"severity": "error",
"expression": "hasValue() or (children().count() > id.count())"
} ],
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Diagnose.Keimbahndiagnose",
"min": 0,
"definition": "Keimbahndiagnosen nach ICD-10-GM.Bei Diagnose eines hereditären Tumordispositionssydroms als Teil der OE ist verpflichtend anzugeben mit ICD10 und ORPHA oder AlphaID",
"isModifier": false,
"short": "Keimbahndiagnose",
"mapping": [ {
"map": "no direct match. Keimbahndiagnose existiert als Konzept nicht, hier könnte / müsste mit Condition.category gearbeitet werden, z.B. SNOMED Hereditary cancer-predisposing syndrome (disorder)",
"identity": "MVGenomSeq-Datenkranz-to-MII-FHIR"
} ],
"type": [ {
"code": "code"
} ],
"max": "*",
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Diagnose.Keimbahndiagnose",
"base": {
"max": "*",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Diagnose.Keimbahndiagnose"
},
"isSummary": false
}, {
"constraint": [ {
"key": "ele-1",
"human": "All FHIR elements must have a @value or children",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element",
"severity": "error",
"expression": "hasValue() or (children().count() > id.count())"
} ],
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Diagnose.HPOPhaenotypisierung",
"min": 0,
"definition": "Human Phenotype Ontology.Bei Diagnose eines hereditären Tumordispositionssydroms als Teil der OE, wenn vorhanden angeben (optional)",
"isModifier": false,
"short": "Phänotypisierung nach HPO",
"mapping": [ {
"map": "Observation.where(valueCodeableConcept.coding.system='http://human-phenotype-ontology.org')",
"identity": "MVGenomSeq-Datenkranz-to-MII-FHIR"
} ],
"type": [ {
"code": "code"
} ],
"max": "*",
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Diagnose.HPOPhaenotypisierung",
"base": {
"max": "*",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Diagnose.HPOPhaenotypisierung"
},
"isSummary": false
}, {
"constraint": [ {
"key": "ele-1",
"human": "All FHIR elements must have a @value or children",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element",
"severity": "error",
"expression": "hasValue() or (children().count() > id.count())"
} ],
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Diagnose.Histologie",
"min": 1,
"definition": "Histologische Morphologie und Verhalten nach ICD-O-3",
"isModifier": false,
"short": "Histologie nach ICD-O-3",
"mapping": [ {
"map": "Condition.extension.where(url='https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-ex-onko-histology-morphology-behavior-icdo3').valueCodeableConcept.coding.code",
"identity": "MVGenomSeq-Datenkranz-to-MII-FHIR"
} ],
"type": [ {
"code": "code"
} ],
"max": "1",
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Diagnose.Histologie",
"base": {
"max": "1",
"min": 1,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Diagnose.Histologie"
},
"isSummary": false
}, {
"constraint": [ {
"key": "ele-1",
"human": "All FHIR elements must have a @value or children",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element",
"severity": "error",
"expression": "hasValue() or (children().count() > id.count())"
} ],
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Diagnose.Topographie",
"min": 1,
"definition": "Topographie des Tumors nach ICD-O-3",
"isModifier": false,
"short": "Topographie nach ICD-O-3",
"mapping": [ {
"map": "Condition.bodySite.coding.code",
"identity": "MVGenomSeq-Datenkranz-to-MII-FHIR"
} ],
"type": [ {
"code": "code"
} ],
"max": "1",
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Diagnose.Topographie",
"base": {
"max": "1",
"min": 1,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Diagnose.Topographie"
},
"isSummary": false
}, {
"constraint": [ {
"key": "ele-1",
"human": "All FHIR elements must have a @value or children",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element",
"severity": "error",
"expression": "hasValue() or (children().count() > id.count())"
} ],
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Diagnose.Grading",
"min": 0,
"definition": "Gibt den Differenzierungsgrad des Tumors entsprechend der aktuellen TNM-Auflage an, Bei der Klassifikation sind die einschlägigen Regeln der Literatur (TNM) zu beachten.",
"isModifier": false,
"short": "Differenzierungsgrad",
"mapping": [ {
"map": "Observation.where(code.coding.code='33732-9' and code.coding.system='http://loinc.org').valueCodeableConcept.coding.code",
"identity": "MVGenomSeq-Datenkranz-to-MII-FHIR"
} ],
"type": [ {
"code": "code"
} ],
"max": "1",
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Diagnose.Grading",
"base": {
"max": "1",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Diagnose.Grading"
},
"isSummary": false
}, {
"constraint": [ {
"key": "ele-1",
"human": "All FHIR elements must have a @value or children",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element",
"severity": "error",
"expression": "hasValue() or (children().count() > id.count())"
} ],
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Diagnose.TNMSchluessel",
"min": 0,
"definition": "TNM-Klassifikation des Tumors",
"isModifier": false,
"short": "TNM-Klassifikation",
"mapping": [ {
"map": "Observation.where(code.coding.code='33732-9' and code.coding.system='http://snomed.info/sct').valueCodeableConcept.coding.code",
"identity": "MVGenomSeq-Datenkranz-to-MII-FHIR"
} ],
"type": [ {
"code": "string"
} ],
"max": "1",
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Diagnose.TNMSchluessel",
"comment": "Note that FHIR strings SHALL NOT exceed 1MB in size",
"base": {
"max": "1",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Diagnose.TNMSchluessel"
},
"isSummary": false
}, {
"constraint": [ {
"key": "ele-1",
"human": "All FHIR elements must have a @value or children",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element",
"severity": "error",
"expression": "hasValue() or (children().count() > id.count())"
} ],
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Diagnose.TNMSystematik",
"min": 0,
"definition": "TNM-Systematik nach AJCC oder UICC",
"isModifier": false,
"short": "TNM-Systematik",
"mapping": [ {
"map": "Laut Krebsregisterdaten nur UICC vorgesehen? kein expiziter Datenpunkt außer Version",
"identity": "MVGenomSeq-Datenkranz-to-MII-FHIR"
} ],
"type": [ {
"code": "code"
} ],
"max": "1",
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Diagnose.TNMSystematik",
"base": {
"max": "1",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Diagnose.TNMSystematik"
},
"isSummary": false
}, {
"constraint": [ {
"key": "ele-1",
"human": "All FHIR elements must have a @value or children",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element",
"severity": "error",
"expression": "hasValue() or (children().count() > id.count())"
} ],
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Diagnose.WeitereKlassifikationen",
"min": 0,
"definition": "Weitere Klassifikationen des Tumors zum Diagnosezeitpunkt",
"isModifier": false,
"short": "Weitere Klassifikationen",
"mapping": [ {
"map": "no direkt match - Observation - Nutzung des Profils WeitereKlassifikationen, aber aufgrund der Vielfalt der Klassifikationen keine direkte Zuordnung möglich",
"identity": "MVGenomSeq-Datenkranz-to-MII-FHIR"
} ],
"type": [ {
"code": "string"
} ],
"max": "*",
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Diagnose.WeitereKlassifikationen",
"comment": "Note that FHIR strings SHALL NOT exceed 1MB in size",
"base": {
"max": "*",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Diagnose.WeitereKlassifikationen"
},
"isSummary": false
}, {
"constraint": [ {
"key": "ele-1",
"human": "All FHIR elements must have a @value or children",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element",
"severity": "error",
"expression": "hasValue() or (children().count() > id.count())"
} ],
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Diagnose.DiagnostischeVoruntersuchungen",
"min": 0,
"definition": "Diagnostische Voruntersuchungen zum Diagnosezeitpunkt. Bewertung der durchgeführten genetischen Diagnostik, nur für heriditäre Prädispositionssyndrome/ Erbliche Tumore",
"isModifier": false,
"short": "Diagnostische Voruntersuchungen",
"mapping": [ {
"map": "no direkt match",
"identity": "MVGenomSeq-Datenkranz-to-MII-FHIR"
} ],
"type": [ {
"code": "code"
} ],
"max": "*",
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Diagnose.DiagnostischeVoruntersuchungen",
"base": {
"max": "*",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Diagnose.DiagnostischeVoruntersuchungen"
},
"isSummary": false
}, {
"constraint": [ {
"key": "ele-1",
"human": "All FHIR elements must have a @value or children",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element",
"severity": "error",
"expression": "hasValue() or (children().count() > id.count())"
} ],
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Vordiagnostik",
"min": 0,
"definition": "Vordiagnostik",
"isModifier": false,
"short": "Vordiagnostik",
"mapping": [ {
"map": "n/a",
"identity": "rim"
}, {
"map": "Vordiagnostik",
"identity": "MVGenomSeq-Datenkranz-to-MII-FHIR"
} ],
"type": [ {
"code": "BackboneElement"
} ],
"extension": [ {
"url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status",
"valueCode": "normative"
}, {
"url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-normative-version",
"valueCode": "4.0.0"
} ],
"max": "*",
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Vordiagnostik",
"condition": [ "ele-1" ],
"base": {
"max": "*",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Vordiagnostik"
}
}, {
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Vordiagnostik.id",
"min": 0,
"definition": "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
"isModifier": false,
"short": "Unique id for inter-element referencing",
"mapping": [ {
"map": "n/a",
"identity": "rim"
} ],
"type": [ {
"code": "http://hl7.org/fhirpath/System.String",
"extension": [ {
"url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
"valueUrl": "string"
} ]
} ],
"representation": [ "xmlAttr" ],
"max": "1",
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Vordiagnostik.id",
"base": {
"max": "1",
"min": 0,
"path": "Element.id"
},
"isSummary": false
}, {
"constraint": [ {
"key": "ele-1",
"human": "All FHIR elements must have a @value or children",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element",
"severity": "error",
"expression": "hasValue() or (children().count() > id.count())"
}, {
"key": "ext-1",
"human": "Must have either extensions or value[x], not both",
"xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
"source": "http://hl7.org/fhir/StructureDefinition/Extension",
"severity": "error",
"expression": "extension.exists() != value.exists()"
} ],
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Vordiagnostik.extension",
"min": 0,
"definition": "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
"isModifier": false,
"short": "Additional content defined by implementations",
"mapping": [ {
"map": "n/a",
"identity": "rim"
} ],
"slicing": {
"rules": "open",
"description": "Extensions are always sliced by (at least) url",
"discriminator": [ {
"path": "url",
"type": "value"
} ]
},
"type": [ {
"code": "Extension"
} ],
"alias": [ "extensions", "user content" ],
"max": "*",
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Vordiagnostik.extension",
"comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
"base": {
"max": "*",
"min": 0,
"path": "Element.extension"
},
"isSummary": false
}, {
"constraint": [ {
"key": "ele-1",
"human": "All FHIR elements must have a @value or children",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element",
"severity": "error",
"expression": "hasValue() or (children().count() > id.count())"
}, {
"key": "ext-1",
"human": "Must have either extensions or value[x], not both",
"xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
"source": "http://hl7.org/fhir/StructureDefinition/Extension",
"severity": "error",
"expression": "extension.exists() != value.exists()"
} ],
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Vordiagnostik.modifierExtension",
"requirements": "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](extensibility.html#modifierExtension).",
"min": 0,
"definition": "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).",
"isModifier": true,
"short": "Extensions that cannot be ignored even if unrecognized",
"mapping": [ {
"map": "N/A",
"identity": "rim"
} ],
"type": [ {
"code": "Extension"
} ],
"alias": [ "extensions", "user content", "modifiers" ],
"max": "*",
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Vordiagnostik.modifierExtension",
"comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
"base": {
"max": "*",
"min": 0,
"path": "BackboneElement.modifierExtension"
},
"isModifierReason": "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them",
"isSummary": true
}, {
"constraint": [ {
"key": "ele-1",
"human": "All FHIR elements must have a @value or children",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element",
"severity": "error",
"expression": "hasValue() or (children().count() > id.count())"
} ],
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Vordiagnostik.ArtDiagnostik",
"min": 1,
"definition": "Diagnostik, die vor dem MV Genomseq, durchgeführt wurde (Vorbefunde)",
"isModifier": false,
"short": "Diagnostik",
"mapping": [ {
"map": "Diagnoste)",
"identity": "MVGenomSeq-Datenkranz-to-MII-FHIR"
} ],
"type": [ {
"code": "code"
} ],
"max": "1",
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Vordiagnostik.ArtDiagnostik",
"base": {
"max": "1",
"min": 1,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Vordiagnostik.ArtDiagnostik"
},
"isSummary": false
}, {
"constraint": [ {
"key": "ele-1",
"human": "All FHIR elements must have a @value or children",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element",
"severity": "error",
"expression": "hasValue() or (children().count() > id.count())"
} ],
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Vordiagnostik.DatumDiagnostik",
"min": 0,
"definition": "Datum der Diagnostik",
"isModifier": false,
"short": "Datum",
"mapping": [ {
"map": "Datum Diagnostik",
"identity": "MVGenomSeq-Datenkranz-to-MII-FHIR"
} ],
"type": [ {
"code": "date"
} ],
"max": "1",
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Vordiagnostik.DatumDiagnostik",
"base": {
"max": "1",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Vordiagnostik.DatumDiagnostik"
},
"isSummary": false
}, {
"constraint": [ {
"key": "ele-1",
"human": "All FHIR elements must have a @value or children",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element",
"severity": "error",
"expression": "hasValue() or (children().count() > id.count())"
} ],
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.MolekulareVorbefunde",
"min": 0,
"definition": "klinisch relevante Ergebnisse der Diagnostik",
"isModifier": false,
"short": "klinisch relevante Ergebnisse der Diagnostik",
"mapping": [ {
"map": "n/a",
"identity": "rim"
}, {
"map": "klinisch relevante Ergebnisse der Diagnostik",
"identity": "MVGenomSeq-Datenkranz-to-MII-FHIR"
} ],
"type": [ {
"code": "BackboneElement"
} ],
"extension": [ {
"url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status",
"valueCode": "normative"
}, {
"url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-normative-version",
"valueCode": "4.0.0"
} ],
"max": "*",
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFall.MolekulareVorbefunde",
"condition": [ "ele-1" ],
"base": {
"max": "*",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.MolekulareVorbefunde"
}
}, {
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.MolekulareVorbefunde.id",
"min": 0,
"definition": "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
"isModifier": false,
"short": "Unique id for inter-element referencing",
"mapping": [ {
"map": "n/a",
"identity": "rim"
} ],
"type": [ {
"code": "http://hl7.org/fhirpath/System.String",
"extension": [ {
"url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
"valueUrl": "string"
} ]
} ],
"representation": [ "xmlAttr" ],
"max": "1",
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFall.MolekulareVorbefunde.id",
"base": {
"max": "1",
"min": 0,
"path": "Element.id"
},
"isSummary": false
}, {
"constraint": [ {
"key": "ele-1",
"human": "All FHIR elements must have a @value or children",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element",
"severity": "error",
"expression": "hasValue() or (children().count() > id.count())"
}, {
"key": "ext-1",
"human": "Must have either extensions or value[x], not both",
"xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
"source": "http://hl7.org/fhir/StructureDefinition/Extension",
"severity": "error",
"expression": "extension.exists() != value.exists()"
} ],
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.MolekulareVorbefunde.extension",
"min": 0,
"definition": "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
"isModifier": false,
"short": "Additional content defined by implementations",
"mapping": [ {
"map": "n/a",
"identity": "rim"
} ],
"slicing": {
"rules": "open",
"description": "Extensions are always sliced by (at least) url",
"discriminator": [ {
"path": "url",
"type": "value"
} ]
},
"type": [ {
"code": "Extension"
} ],
"alias": [ "extensions", "user content" ],
"max": "*",
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFall.MolekulareVorbefunde.extension",
"comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
"base": {
"max": "*",
"min": 0,
"path": "Element.extension"
},
"isSummary": false
}, {
"constraint": [ {
"key": "ele-1",
"human": "All FHIR elements must have a @value or children",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element",
"severity": "error",
"expression": "hasValue() or (children().count() > id.count())"
}, {
"key": "ext-1",
"human": "Must have either extensions or value[x], not both",
"xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
"source": "http://hl7.org/fhir/StructureDefinition/Extension",
"severity": "error",
"expression": "extension.exists() != value.exists()"
} ],
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.MolekulareVorbefunde.modifierExtension",
"requirements": "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](extensibility.html#modifierExtension).",
"min": 0,
"definition": "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).",
"isModifier": true,
"short": "Extensions that cannot be ignored even if unrecognized",
"mapping": [ {
"map": "N/A",
"identity": "rim"
} ],
"type": [ {
"code": "Extension"
} ],
"alias": [ "extensions", "user content", "modifiers" ],
"max": "*",
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFall.MolekulareVorbefunde.modifierExtension",
"comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
"base": {
"max": "*",
"min": 0,
"path": "BackboneElement.modifierExtension"
},
"isModifierReason": "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them",
"isSummary": true
}, {
"constraint": [ {
"key": "ele-1",
"human": "All FHIR elements must have a @value or children",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element",
"severity": "error",
"expression": "hasValue() or (children().count() > id.count())"
} ],
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.MolekulareVorbefunde.Gen",
"min": 1,
"definition": "Gen kodiert nach HGNC",
"isModifier": false,
"short": "Gen",
"mapping": [ {
"map": "Genert nach HGNC",
"identity": "MVGenomSeq-Datenkranz-to-MII-FHIR"
} ],
"type": [ {
"code": "code"
} ],
"max": "1",
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFall.MolekulareVorbefunde.Gen",
"base": {
"max": "1",
"min": 1,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.MolekulareVorbefunde.Gen"
},
"isSummary": false
}, {
"constraint": [ {
"key": "ele-1",
"human": "All FHIR elements must have a @value or children",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element",
"severity": "error",
"expression": "hasValue() or (children().count() > id.count())"
} ],
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.MolekulareVorbefunde.Transkript",
"min": 0,
"definition": "Transkript kodiert nach Ensembl/RefSeq",
"isModifier": false,
"short": "Transkript",
"mapping": [ {
"map": "Transkriranskript kodiert nach Ensembl/RefSeq",
"identity": "MVGenomSeq-Datenkranz-to-MII-FHIR"
} ],
"type": [ {
"code": "code"
} ],
"max": "1",
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFall.MolekulareVorbefunde.Transkript",
"base": {
"max": "1",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.MolekulareVorbefunde.Transkript"
},
"isSummary": false
}, {
"constraint": [ {
"key": "ele-1",
"human": "All FHIR elements must have a @value or children",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element",
"severity": "error",
"expression": "hasValue() or (children().count() > id.count())"
} ],
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.MolekulareVorbefunde.DNAChange",
"min": 0,
"definition": "DNA-Verändung nach cHGVS",
"isModifier": false,
"short": "DNA-Veränderung",
"mapping": [ {
"map": "DNA-VeränVerändung nach cHGVS",
"identity": "MVGenomSeq-Datenkranz-to-MII-FHIR"
} ],
"type": [ {
"code": "code"
} ],
"max": "1",
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFall.MolekulareVorbefunde.DNAChange",
"base": {
"max": "1",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.MolekulareVorbefunde.DNAChange"
},
"isSummary": false
}, {
"constraint": [ {
"key": "ele-1",
"human": "All FHIR elements must have a @value or children",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element",
"severity": "error",
"expression": "hasValue() or (children().count() > id.count())"
} ],
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.MolekulareVorbefunde.ProteinChange",
"min": 0,
"definition": "Protein-Veränderung nach pHGVS",
"isModifier": false,
"short": "Protein-Veränderung",
"mapping": [ {
"map": "Protein-Verändotein-Veränderung nach pHGVS",
"identity": "MVGenomSeq-Datenkranz-to-MII-FHIR"
} ],
"type": [ {
"code": "code"
} ],
"max": "1",
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFall.MolekulareVorbefunde.ProteinChange",
"base": {
"max": "1",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.MolekulareVorbefunde.ProteinChange"
},
"isSummary": false
}, {
"constraint": [ {
"key": "ele-1",
"human": "All FHIR elements must have a @value or children",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element",
"severity": "error",
"expression": "hasValue() or (children().count() > id.count())"
} ],
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.MolekulareVorbefunde.TypAlteration",
"min": 0,
"definition": "Typ der Alteration / Variantenklasse nach Sequence ontology (SO)",
"isModifier": false,
"short": "Typ der Alteration",
"mapping": [ {
"map": "Typ der Alteratr Alteration / Variantenklasse nach Sequence ontology (SO)",
"identity": "MVGenomSeq-Datenkranz-to-MII-FHIR"
} ],
"type": [ {
"code": "code"
} ],
"max": "1",
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFall.MolekulareVorbefunde.TypAlteration",
"base": {
"max": "1",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.MolekulareVorbefunde.TypAlteration"
},
"isSummary": false
}, {
"constraint": [ {
"key": "ele-1",
"human": "All FHIR elements must have a @value or children",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element",
"severity": "error",
"expression": "hasValue() or (children().count() > id.count())"
} ],
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.MolekulareVorbefunde.KomplexeAlteration",
"min": 0,
"definition": "Ausführliche Beschreibung bei komplexen Alteration z.B. Fusion",
"isModifier": false,
"short": "Komplexe Alteration",
"mapping": [ {
"map": "Komplexe AlteratAusführliche Beschreibung",
"identity": "MVGenomSeq-Datenkranz-to-MII-FHIR"
} ],
"type": [ {
"code": "string"
} ],
"max": "1",
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFall.MolekulareVorbefunde.KomplexeAlteration",
"comment": "Note that FHIR strings SHALL NOT exceed 1MB in size",
"base": {
"max": "1",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.MolekulareVorbefunde.KomplexeAlteration"
},
"isSummary": false
}, {
"constraint": [ {
"key": "ele-1",
"human": "All FHIR elements must have a @value or children",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element",
"severity": "error",
"expression": "hasValue() or (children().count() > id.count())"
} ],
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.SystemischeVortherapien",
"min": 0,
"definition": "Systemische Vortherapien",
"isModifier": false,
"short": "Systemische Vortherapien",
"mapping": [ {
"map": "n/a",
"identity": "rim"
}, {
"map": "Procedure",
"identity": "MVGenomSeq-Datenkranz-to-MII-FHIR"
} ],
"type": [ {
"code": "BackboneElement"
} ],
"extension": [ {
"url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status",
"valueCode": "normative"
}, {
"url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-normative-version",
"valueCode": "4.0.0"
} ],
"max": "*",
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFall.SystemischeVortherapien",
"condition": [ "ele-1" ],
"base": {
"max": "*",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.SystemischeVortherapien"
}
}, {
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.SystemischeVortherapien.id",
"min": 0,
"definition": "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
"isModifier": false,
"short": "Unique id for inter-element referencing",
"mapping": [ {
"map": "n/a",
"identity": "rim"
} ],
"type": [ {
"code": "http://hl7.org/fhirpath/System.String",
"extension": [ {
"url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
"valueUrl": "string"
} ]
} ],
"representation": [ "xmlAttr" ],
"max": "1",
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFall.SystemischeVortherapien.id",
"base": {
"max": "1",
"min": 0,
"path": "Element.id"
},
"isSummary": false
}, {
"constraint": [ {
"key": "ele-1",
"human": "All FHIR elements must have a @value or children",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element",
"severity": "error",
"expression": "hasValue() or (children().count() > id.count())"
}, {
"key": "ext-1",
"human": "Must have either extensions or value[x], not both",
"xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
"source": "http://hl7.org/fhir/StructureDefinition/Extension",
"severity": "error",
"expression": "extension.exists() != value.exists()"
} ],
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.SystemischeVortherapien.extension",
"min": 0,
"definition": "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
"isModifier": false,
"short": "Additional content defined by implementations",
"mapping": [ {
"map": "n/a",
"identity": "rim"
} ],
"slicing": {
"rules": "open",
"description": "Extensions are always sliced by (at least) url",
"discriminator": [ {
"path": "url",
"type": "value"
} ]
},
"type": [ {
"code": "Extension"
} ],
"alias": [ "extensions", "user content" ],
"max": "*",
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFall.SystemischeVortherapien.extension",
"comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
"base": {
"max": "*",
"min": 0,
"path": "Element.extension"
},
"isSummary": false
}, {
"constraint": [ {
"key": "ele-1",
"human": "All FHIR elements must have a @value or children",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element",
"severity": "error",
"expression": "hasValue() or (children().count() > id.count())"
}, {
"key": "ext-1",
"human": "Must have either extensions or value[x], not both",
"xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
"source": "http://hl7.org/fhir/StructureDefinition/Extension",
"severity": "error",
"expression": "extension.exists() != value.exists()"
} ],
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.SystemischeVortherapien.modifierExtension",
"requirements": "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](extensibility.html#modifierExtension).",
"min": 0,
"definition": "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).",
"isModifier": true,
"short": "Extensions that cannot be ignored even if unrecognized",
"mapping": [ {
"map": "N/A",
"identity": "rim"
} ],
"type": [ {
"code": "Extension"
} ],
"alias": [ "extensions", "user content", "modifiers" ],
"max": "*",
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFall.SystemischeVortherapien.modifierExtension",
"comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
"base": {
"max": "*",
"min": 0,
"path": "BackboneElement.modifierExtension"
},
"isModifierReason": "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them",
"isSummary": true
}, {
"constraint": [ {
"key": "ele-1",
"human": "All FHIR elements must have a @value or children",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element",
"severity": "error",
"expression": "hasValue() or (children().count() > id.count())"
} ],
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.SystemischeVortherapien.ArtTherapie",
"min": 1,
"definition": "Bezug der Vortherapie zu einer operativen Therapie, z.B. adjuvant, neoadjuvant",
"isModifier": false,
"short": "Bezug zur operativen Therapie",
"mapping": [ {
"map": "Procedure.extension.where(url='StellungZurOp')",
"identity": "MVGenomSeq-Datenkranz-to-MII-FHIR"
} ],
"type": [ {
"code": "code"
} ],
"max": "1",
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFall.SystemischeVortherapien.ArtTherapie",
"base": {
"max": "1",
"min": 1,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.SystemischeVortherapien.ArtTherapie"
},
"isSummary": false
}, {
"constraint": [ {
"key": "ele-1",
"human": "All FHIR elements must have a @value or children",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element",
"severity": "error",
"expression": "hasValue() or (children().count() > id.count())"
} ],
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.SystemischeVortherapien.IntentionTherapie",
"min": 0,
"definition": "Intention der Vortherapie, z.B. kurativ, palliativ",
"isModifier": false,
"short": "Intention",
"mapping": [ {
"map": "Procedure.extension.where(url='Intention')",
"identity": "MVGenomSeq-Datenkranz-to-MII-FHIR"
} ],
"type": [ {
"code": "code"
} ],
"max": "1",
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFall.SystemischeVortherapien.IntentionTherapie",
"base": {
"max": "1",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.SystemischeVortherapien.IntentionTherapie"
},
"isSummary": false
}, {
"constraint": [ {
"key": "ele-1",
"human": "All FHIR elements must have a @value or children",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element",
"severity": "error",
"expression": "hasValue() or (children().count() > id.count())"
} ],
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.SystemischeVortherapien.Substanz",
"min": 0,
"definition": "Substanz der Vortherapie nach ATC oder Text bei nicht-ATC-Wirkstoffen",
"isModifier": false,
"short": "Substanz",
"mapping": [ {
"map": "MedicationStatement.medicationCode.coding[atc-de].code",
"identity": "MVGenomSeq-Datenkranz-to-MII-FHIR"
} ],
"type": [ {
"code": "code"
} ],
"max": "*",
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFall.SystemischeVortherapien.Substanz",
"base": {
"max": "*",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.SystemischeVortherapien.Substanz"
},
"isSummary": false
}, {
"constraint": [ {
"key": "ele-1",
"human": "All FHIR elements must have a @value or children",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element",
"severity": "error",
"expression": "hasValue() or (children().count() > id.count())"
} ],
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.SystemischeVortherapien.Therapiestart",
"min": 0,
"definition": "Startdatum der Vortherapie. Wenn Datum unbekannt, dann 15. des Monats",
"isModifier": false,
"short": "Startdatum",
"mapping": [ {
"map": "Procedure.effectivePeriod.start",
"identity": "MVGenomSeq-Datenkranz-to-MII-FHIR"
} ],
"type": [ {
"code": "date"
} ],
"max": "1",
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFall.SystemischeVortherapien.Therapiestart",
"base": {
"max": "1",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.SystemischeVortherapien.Therapiestart"
},
"isSummary": false
}, {
"constraint": [ {
"key": "ele-1",
"human": "All FHIR elements must have a @value or children",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element",
"severity": "error",
"expression": "hasValue() or (children().count() > id.count())"
} ],
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.SystemischeVortherapien.Therapieende",
"min": 0,
"definition": "Enddatum der Vortherapie. Wenn Datum unbekannt, dann 15. des Monats",
"isModifier": false,
"short": "Enddatum",
"mapping": [ {
"map": "Procedure.effectivePeriod.end",
"identity": "MVGenomSeq-Datenkranz-to-MII-FHIR"
} ],
"type": [ {
"code": "date"
} ],
"max": "1",
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFall.SystemischeVortherapien.Therapieende",
"base": {
"max": "1",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.SystemischeVortherapien.Therapieende"
},
"isSummary": false
}, {
"constraint": [ {
"key": "ele-1",
"human": "All FHIR elements must have a @value or children",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element",
"severity": "error",
"expression": "hasValue() or (children().count() > id.count())"
} ],
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.SystemischeVortherapien.EndeGrund",
"min": 0,
"definition": "Grund für das Ende der Vortherapie",
"isModifier": false,
"short": "Ende der Therapie",
"mapping": [ {
"map": "Procedure.outcome",
"identity": "MVGenomSeq-Datenkranz-to-MII-FHIR"
} ],
"type": [ {
"code": "code"
} ],
"max": "1",
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFall.SystemischeVortherapien.EndeGrund",
"base": {
"max": "1",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.SystemischeVortherapien.EndeGrund"
},
"isSummary": false
}, {
"constraint": [ {
"key": "ele-1",
"human": "All FHIR elements must have a @value or children",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element",
"severity": "error",
"expression": "hasValue() or (children().count() > id.count())"
} ],
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.SystemischeVortherapien.TherapieAnsprechen",
"min": 0,
"definition": "Therapieansprechen der fallrelevante, systemische Vortherapie (PD: Progression, SD:Stabile Erkrankung, PR:Partielle Remission, CR:Komplette Remission)",
"isModifier": false,
"short": "Ansprechen",
"mapping": [ {
"map": "Verlauf.valueCodeableConcept.coding.code",
"identity": "MVGenomSeq-Datenkranz-to-MII-FHIR"
} ],
"type": [ {
"code": "code"
} ],
"max": "1",
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFall.SystemischeVortherapien.TherapieAnsprechen",
"base": {
"max": "1",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.SystemischeVortherapien.TherapieAnsprechen"
},
"isSummary": false
}, {
"constraint": [ {
"key": "ele-1",
"human": "All FHIR elements must have a @value or children",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element",
"severity": "error",
"expression": "hasValue() or (children().count() > id.count())"
} ],
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.SystemischeVortherapien.TherapieAnsprechenDatum",
"min": 0,
"definition": "Datum des Ansprechens der Vortherapie",
"isModifier": false,
"short": "Datum",
"mapping": [ {
"map": "Verlauf.effectiveDateTime",
"identity": "MVGenomSeq-Datenkranz-to-MII-FHIR"
} ],
"type": [ {
"code": "date"
} ],
"max": "1",
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFall.SystemischeVortherapien.TherapieAnsprechenDatum",
"base": {
"max": "1",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.SystemischeVortherapien.TherapieAnsprechenDatum"
},
"isSummary": false
}, {
"constraint": [ {
"key": "ele-1",
"human": "All FHIR elements must have a @value or children",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element",
"severity": "error",
"expression": "hasValue() or (children().count() > id.count())"
} ],
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular",
"min": 0,
"definition": "Molekulare Diagnostik",
"isModifier": false,
"short": "Molekulare Diagnostik",
"mapping": [ {
"map": "n/a",
"identity": "rim"
} ],
"type": [ {
"code": "BackboneElement"
} ],
"extension": [ {
"url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status",
"valueCode": "normative"
}, {
"url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-normative-version",
"valueCode": "4.0.0"
} ],
"max": "*",
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular",
"condition": [ "ele-1" ],
"base": {
"max": "*",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular"
}
}, {
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.id",
"min": 0,
"definition": "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
"isModifier": false,
"short": "Unique id for inter-element referencing",
"mapping": [ {
"map": "n/a",
"identity": "rim"
} ],
"type": [ {
"code": "http://hl7.org/fhirpath/System.String",
"extension": [ {
"url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
"valueUrl": "string"
} ]
} ],
"representation": [ "xmlAttr" ],
"max": "1",
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.id",
"base": {
"max": "1",
"min": 0,
"path": "Element.id"
},
"isSummary": false
}, {
"constraint": [ {
"key": "ele-1",
"human": "All FHIR elements must have a @value or children",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element",
"severity": "error",
"expression": "hasValue() or (children().count() > id.count())"
}, {
"key": "ext-1",
"human": "Must have either extensions or value[x], not both",
"xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
"source": "http://hl7.org/fhir/StructureDefinition/Extension",
"severity": "error",
"expression": "extension.exists() != value.exists()"
} ],
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.extension",
"min": 0,
"definition": "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
"isModifier": false,
"short": "Additional content defined by implementations",
"mapping": [ {
"map": "n/a",
"identity": "rim"
} ],
"slicing": {
"rules": "open",
"description": "Extensions are always sliced by (at least) url",
"discriminator": [ {
"path": "url",
"type": "value"
} ]
},
"type": [ {
"code": "Extension"
} ],
"alias": [ "extensions", "user content" ],
"max": "*",
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.extension",
"comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
"base": {
"max": "*",
"min": 0,
"path": "Element.extension"
},
"isSummary": false
}, {
"constraint": [ {
"key": "ele-1",
"human": "All FHIR elements must have a @value or children",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element",
"severity": "error",
"expression": "hasValue() or (children().count() > id.count())"
}, {
"key": "ext-1",
"human": "Must have either extensions or value[x], not both",
"xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
"source": "http://hl7.org/fhir/StructureDefinition/Extension",
"severity": "error",
"expression": "extension.exists() != value.exists()"
} ],
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.modifierExtension",
"requirements": "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](extensibility.html#modifierExtension).",
"min": 0,
"definition": "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).",
"isModifier": true,
"short": "Extensions that cannot be ignored even if unrecognized",
"mapping": [ {
"map": "N/A",
"identity": "rim"
} ],
"type": [ {
"code": "Extension"
} ],
"alias": [ "extensions", "user content", "modifiers" ],
"max": "*",
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.modifierExtension",
"comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
"base": {
"max": "*",
"min": 0,
"path": "BackboneElement.modifierExtension"
},
"isModifierReason": "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them",
"isSummary": true
}, {
"constraint": [ {
"key": "ele-1",
"human": "All FHIR elements must have a @value or children",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element",
"severity": "error",
"expression": "hasValue() or (children().count() > id.count())"
} ],
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.EinfacheVariante",
"min": 0,
"definition": "Einfache Variante inkl. Fusionen im codierenden Bereich",
"isModifier": false,
"short": "Einfache Variante inkl. Fusionen im codierenden Bereich",
"mapping": [ {
"map": "n/a",
"identity": "rim"
} ],
"type": [ {
"code": "BackboneElement"
} ],
"extension": [ {
"url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status",
"valueCode": "normative"
}, {
"url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-normative-version",
"valueCode": "4.0.0"
} ],
"max": "*",
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.EinfacheVariante",
"condition": [ "ele-1" ],
"base": {
"max": "*",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.EinfacheVariante"
}
}, {
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.EinfacheVariante.id",
"min": 0,
"definition": "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
"isModifier": false,
"short": "Unique id for inter-element referencing",
"mapping": [ {
"map": "n/a",
"identity": "rim"
} ],
"type": [ {
"code": "http://hl7.org/fhirpath/System.String",
"extension": [ {
"url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
"valueUrl": "string"
} ]
} ],
"representation": [ "xmlAttr" ],
"max": "1",
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.EinfacheVariante.id",
"base": {
"max": "1",
"min": 0,
"path": "Element.id"
},
"isSummary": false
}, {
"constraint": [ {
"key": "ele-1",
"human": "All FHIR elements must have a @value or children",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element",
"severity": "error",
"expression": "hasValue() or (children().count() > id.count())"
}, {
"key": "ext-1",
"human": "Must have either extensions or value[x], not both",
"xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
"source": "http://hl7.org/fhir/StructureDefinition/Extension",
"severity": "error",
"expression": "extension.exists() != value.exists()"
} ],
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.EinfacheVariante.extension",
"min": 0,
"definition": "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
"isModifier": false,
"short": "Additional content defined by implementations",
"mapping": [ {
"map": "n/a",
"identity": "rim"
} ],
"slicing": {
"rules": "open",
"description": "Extensions are always sliced by (at least) url",
"discriminator": [ {
"path": "url",
"type": "value"
} ]
},
"type": [ {
"code": "Extension"
} ],
"alias": [ "extensions", "user content" ],
"max": "*",
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.EinfacheVariante.extension",
"comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
"base": {
"max": "*",
"min": 0,
"path": "Element.extension"
},
"isSummary": false
}, {
"constraint": [ {
"key": "ele-1",
"human": "All FHIR elements must have a @value or children",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element",
"severity": "error",
"expression": "hasValue() or (children().count() > id.count())"
}, {
"key": "ext-1",
"human": "Must have either extensions or value[x], not both",
"xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
"source": "http://hl7.org/fhir/StructureDefinition/Extension",
"severity": "error",
"expression": "extension.exists() != value.exists()"
} ],
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.EinfacheVariante.modifierExtension",
"requirements": "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](extensibility.html#modifierExtension).",
"min": 0,
"definition": "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).",
"isModifier": true,
"short": "Extensions that cannot be ignored even if unrecognized",
"mapping": [ {
"map": "N/A",
"identity": "rim"
} ],
"type": [ {
"code": "Extension"
} ],
"alias": [ "extensions", "user content", "modifiers" ],
"max": "*",
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.EinfacheVariante.modifierExtension",
"comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
"base": {
"max": "*",
"min": 0,
"path": "BackboneElement.modifierExtension"
},
"isModifierReason": "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them",
"isSummary": true
}, {
"constraint": [ {
"key": "ele-1",
"human": "All FHIR elements must have a @value or children",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element",
"severity": "error",
"expression": "hasValue() or (children().count() > id.count())"
} ],
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.EinfacheVariante.Identifier",
"min": 0,
"definition": "interner Identifikator der Variante",
"isModifier": false,
"short": "Identifier",
"type": [ {
"code": "string"
} ],
"max": "1",
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.EinfacheVariante.Identifier",
"comment": "Note that FHIR strings SHALL NOT exceed 1MB in size",
"base": {
"max": "1",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.EinfacheVariante.Identifier"
},
"isSummary": false
}, {
"constraint": [ {
"key": "ele-1",
"human": "All FHIR elements must have a @value or children",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element",
"severity": "error",
"expression": "hasValue() or (children().count() > id.count())"
} ],
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.EinfacheVariante.Gen",
"min": 1,
"definition": "Gen kodiert nach HGNC",
"isModifier": false,
"short": "Gen",
"type": [ {
"code": "code"
} ],
"max": "1",
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.EinfacheVariante.Gen",
"base": {
"max": "1",
"min": 1,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.EinfacheVariante.Gen"
},
"isSummary": false
}, {
"constraint": [ {
"key": "ele-1",
"human": "All FHIR elements must have a @value or children",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element",
"severity": "error",
"expression": "hasValue() or (children().count() > id.count())"
} ],
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.EinfacheVariante.Transkript",
"min": 0,
"definition": "Transkript kodiert nach Ensembl/RefSeq",
"isModifier": false,
"short": "Transkript",
"type": [ {
"code": "code"
} ],
"max": "1",
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.EinfacheVariante.Transkript",
"base": {
"max": "1",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.EinfacheVariante.Transkript"
},
"isSummary": false
}, {
"constraint": [ {
"key": "ele-1",
"human": "All FHIR elements must have a @value or children",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element",
"severity": "error",
"expression": "hasValue() or (children().count() > id.count())"
} ],
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.EinfacheVariante.DNAChange",
"min": 0,
"definition": "DNA-Verändung nach cHGVS",
"isModifier": false,
"short": "DNA-Veränderung",
"type": [ {
"code": "code"
} ],
"max": "1",
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.EinfacheVariante.DNAChange",
"base": {
"max": "1",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.EinfacheVariante.DNAChange"
},
"isSummary": false
}, {
"constraint": [ {
"key": "ele-1",
"human": "All FHIR elements must have a @value or children",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element",
"severity": "error",
"expression": "hasValue() or (children().count() > id.count())"
} ],
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.EinfacheVariante.ProteinChange",
"min": 0,
"definition": "Protein-Veränderung nach pHGVS",
"isModifier": false,
"short": "Protein-Veränderung",
"type": [ {
"code": "code"
} ],
"max": "1",
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.EinfacheVariante.ProteinChange",
"base": {
"max": "1",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.EinfacheVariante.ProteinChange"
},
"isSummary": false
}, {
"constraint": [ {
"key": "ele-1",
"human": "All FHIR elements must have a @value or children",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element",
"severity": "error",
"expression": "hasValue() or (children().count() > id.count())"
} ],
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.EinfacheVariante.TypAlteration",
"min": 0,
"definition": "Typ der Alteration / Variantenklasse nach Sequence ontology (SO)",
"isModifier": false,
"short": "Typ der Alteration",
"type": [ {
"code": "code"
} ],
"max": "1",
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.EinfacheVariante.TypAlteration",
"base": {
"max": "1",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.EinfacheVariante.TypAlteration"
},
"isSummary": false
}, {
"constraint": [ {
"key": "ele-1",
"human": "All FHIR elements must have a @value or children",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element",
"severity": "error",
"expression": "hasValue() or (children().count() > id.count())"
} ],
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.EinfacheVariante.Lokalization",
"min": 0,
"definition": "Lokalisation im kodierenden, regulatorischen oder intergenischen Bereich",
"isModifier": false,
"short": "Lokalisation der Variante",
"type": [ {
"code": "code"
} ],
"max": "1",
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.EinfacheVariante.Lokalization",
"base": {
"max": "1",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.EinfacheVariante.Lokalization"
},
"isSummary": false
}, {
"constraint": [ {
"key": "ele-1",
"human": "All FHIR elements must have a @value or children",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element",
"severity": "error",
"expression": "hasValue() or (children().count() > id.count())"
} ],
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.EinfacheVariante.LossOfHeterozygosity",
"min": 0,
"definition": "Loss of Heterozygosity (LOH) im Bereich der Variante Ja / Nein",
"isModifier": false,
"short": "Loss of Heterozygosity (LOH)",
"type": [ {
"code": "code"
} ],
"max": "1",
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.EinfacheVariante.LossOfHeterozygosity",
"base": {
"max": "1",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.EinfacheVariante.LossOfHeterozygosity"
},
"isSummary": false
}, {
"constraint": [ {
"key": "ele-1",
"human": "All FHIR elements must have a @value or children",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element",
"severity": "error",
"expression": "hasValue() or (children().count() > id.count())"
} ],
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.CopyNumberVariante",
"min": 0,
"definition": "Variante mit Kopienzahlveränderung (Copy Number Variation, CNV)",
"isModifier": false,
"short": "Variante mit Kopienzahlveränderung (Copy Number Variation, CNV)",
"mapping": [ {
"map": "n/a",
"identity": "rim"
} ],
"type": [ {
"code": "BackboneElement"
} ],
"extension": [ {
"url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status",
"valueCode": "normative"
}, {
"url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-normative-version",
"valueCode": "4.0.0"
} ],
"max": "*",
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.CopyNumberVariante",
"condition": [ "ele-1" ],
"base": {
"max": "*",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.CopyNumberVariante"
}
}, {
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.CopyNumberVariante.id",
"min": 0,
"definition": "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
"isModifier": false,
"short": "Unique id for inter-element referencing",
"mapping": [ {
"map": "n/a",
"identity": "rim"
} ],
"type": [ {
"code": "http://hl7.org/fhirpath/System.String",
"extension": [ {
"url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
"valueUrl": "string"
} ]
} ],
"representation": [ "xmlAttr" ],
"max": "1",
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.CopyNumberVariante.id",
"base": {
"max": "1",
"min": 0,
"path": "Element.id"
},
"isSummary": false
}, {
"constraint": [ {
"key": "ele-1",
"human": "All FHIR elements must have a @value or children",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element",
"severity": "error",
"expression": "hasValue() or (children().count() > id.count())"
}, {
"key": "ext-1",
"human": "Must have either extensions or value[x], not both",
"xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
"source": "http://hl7.org/fhir/StructureDefinition/Extension",
"severity": "error",
"expression": "extension.exists() != value.exists()"
} ],
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.CopyNumberVariante.extension",
"min": 0,
"definition": "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
"isModifier": false,
"short": "Additional content defined by implementations",
"mapping": [ {
"map": "n/a",
"identity": "rim"
} ],
"slicing": {
"rules": "open",
"description": "Extensions are always sliced by (at least) url",
"discriminator": [ {
"path": "url",
"type": "value"
} ]
},
"type": [ {
"code": "Extension"
} ],
"alias": [ "extensions", "user content" ],
"max": "*",
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.CopyNumberVariante.extension",
"comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
"base": {
"max": "*",
"min": 0,
"path": "Element.extension"
},
"isSummary": false
}, {
"constraint": [ {
"key": "ele-1",
"human": "All FHIR elements must have a @value or children",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element",
"severity": "error",
"expression": "hasValue() or (children().count() > id.count())"
}, {
"key": "ext-1",
"human": "Must have either extensions or value[x], not both",
"xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
"source": "http://hl7.org/fhir/StructureDefinition/Extension",
"severity": "error",
"expression": "extension.exists() != value.exists()"
} ],
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.CopyNumberVariante.modifierExtension",
"requirements": "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](extensibility.html#modifierExtension).",
"min": 0,
"definition": "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).",
"isModifier": true,
"short": "Extensions that cannot be ignored even if unrecognized",
"mapping": [ {
"map": "N/A",
"identity": "rim"
} ],
"type": [ {
"code": "Extension"
} ],
"alias": [ "extensions", "user content", "modifiers" ],
"max": "*",
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.CopyNumberVariante.modifierExtension",
"comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
"base": {
"max": "*",
"min": 0,
"path": "BackboneElement.modifierExtension"
},
"isModifierReason": "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them",
"isSummary": true
}, {
"constraint": [ {
"key": "ele-1",
"human": "All FHIR elements must have a @value or children",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element",
"severity": "error",
"expression": "hasValue() or (children().count() > id.count())"
} ],
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.CopyNumberVariante.Identifier",
"min": 0,
"definition": "interner Identifikator der Variante",
"isModifier": false,
"short": "Identifier",
"type": [ {
"code": "string"
} ],
"max": "1",
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.CopyNumberVariante.Identifier",
"comment": "Note that FHIR strings SHALL NOT exceed 1MB in size",
"base": {
"max": "1",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.CopyNumberVariante.Identifier"
},
"isSummary": false
}, {
"constraint": [ {
"key": "ele-1",
"human": "All FHIR elements must have a @value or children",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element",
"severity": "error",
"expression": "hasValue() or (children().count() > id.count())"
} ],
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.CopyNumberVariante.CNVTyp",
"min": 0,
"definition": "Komplettverlust, partieller Verlust, Amplifikation",
"isModifier": false,
"short": "CNV-Typ",
"mapping": [ {
"map": "n/a",
"identity": "rim"
} ],
"type": [ {
"code": "BackboneElement"
} ],
"extension": [ {
"url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status",
"valueCode": "normative"
}, {
"url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-normative-version",
"valueCode": "4.0.0"
} ],
"max": "*",
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.CopyNumberVariante.CNVTyp",
"condition": [ "ele-1" ],
"base": {
"max": "*",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.CopyNumberVariante.CNVTyp"
}
}, {
"constraint": [ {
"key": "ele-1",
"human": "All FHIR elements must have a @value or children",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element",
"severity": "error",
"expression": "hasValue() or (children().count() > id.count())"
} ],
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.CopyNumberVariante.Quellprobe",
"min": 0,
"definition": "Art der Quellprobe (somatisch oder Keimbahn)",
"isModifier": false,
"short": "Art der Quellprobe",
"type": [ {
"code": "code"
} ],
"max": "1",
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.CopyNumberVariante.Quellprobe",
"base": {
"max": "1",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.CopyNumberVariante.Quellprobe"
},
"isSummary": false
}, {
"constraint": [ {
"key": "ele-1",
"human": "All FHIR elements must have a @value or children",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element",
"severity": "error",
"expression": "hasValue() or (children().count() > id.count())"
} ],
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.CopyNumberVariante.Gen",
"min": 0,
"definition": "Gen kodiert nach HGNC - falls nur ein Gen betreffend",
"isModifier": false,
"short": "Gen",
"type": [ {
"code": "code"
} ],
"max": "1",
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.CopyNumberVariante.Gen",
"base": {
"max": "1",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.CopyNumberVariante.Gen"
},
"isSummary": false
}, {
"constraint": [ {
"key": "ele-1",
"human": "All FHIR elements must have a @value or children",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element",
"severity": "error",
"expression": "hasValue() or (children().count() > id.count())"
} ],
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.CopyNumberVariante.Chromosom",
"min": 0,
"definition": "Chromosom",
"isModifier": false,
"short": "Chromosom",
"type": [ {
"code": "code"
} ],
"max": "1",
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.CopyNumberVariante.Chromosom",
"base": {
"max": "1",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.CopyNumberVariante.Chromosom"
},
"isSummary": false
}, {
"constraint": [ {
"key": "ele-1",
"human": "All FHIR elements must have a @value or children",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element",
"severity": "error",
"expression": "hasValue() or (children().count() > id.count())"
} ],
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.CopyNumberVariante.CNVStartPosition",
"min": 0,
"definition": "Startposition des CNV basierend auf Hg38",
"isModifier": false,
"short": "CNV-Start",
"type": [ {
"code": "integer"
} ],
"max": "1",
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.CopyNumberVariante.CNVStartPosition",
"comment": "32 bit number; for values larger than this, use decimal",
"base": {
"max": "1",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.CopyNumberVariante.CNVStartPosition"
},
"isSummary": false
}, {
"constraint": [ {
"key": "ele-1",
"human": "All FHIR elements must have a @value or children",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element",
"severity": "error",
"expression": "hasValue() or (children().count() > id.count())"
} ],
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.CopyNumberVariante.CNVEndPosition",
"min": 0,
"definition": "Endposition des CNV basierend auf Hg38",
"isModifier": false,
"short": "CNV-Ende",
"type": [ {
"code": "integer"
} ],
"max": "1",
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.CopyNumberVariante.CNVEndPosition",
"comment": "32 bit number; for values larger than this, use decimal",
"base": {
"max": "1",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.CopyNumberVariante.CNVEndPosition"
},
"isSummary": false
}, {
"constraint": [ {
"key": "ele-1",
"human": "All FHIR elements must have a @value or children",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element",
"severity": "error",
"expression": "hasValue() or (children().count() > id.count())"
} ],
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.CopyNumberVariante.CopyNumber",
"min": 0,
"definition": "Copy Number",
"isModifier": false,
"short": "Copy Number",
"type": [ {
"code": "integer"
} ],
"max": "1",
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.CopyNumberVariante.CopyNumber",
"comment": "32 bit number; for values larger than this, use decimal",
"base": {
"max": "1",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.CopyNumberVariante.CopyNumber"
},
"isSummary": false
}, {
"constraint": [ {
"key": "ele-1",
"human": "All FHIR elements must have a @value or children",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element",
"severity": "error",
"expression": "hasValue() or (children().count() > id.count())"
} ],
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.CopyNumberVariante.Lokalization",
"min": 0,
"definition": "Lokalisation im kodierenden, regulatorischen oder intergenischen Bereich",
"isModifier": false,
"short": "Lokalisation der Variante",
"type": [ {
"code": "code"
} ],
"max": "1",
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.CopyNumberVariante.Lokalization",
"base": {
"max": "1",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.CopyNumberVariante.Lokalization"
},
"isSummary": false
}, {
"constraint": [ {
"key": "ele-1",
"human": "All FHIR elements must have a @value or children",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element",
"severity": "error",
"expression": "hasValue() or (children().count() > id.count())"
} ],
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.StrukturelleVariante",
"min": 0,
"definition": "Strukturelle Variante",
"isModifier": false,
"short": "Strukturelle Variante",
"mapping": [ {
"map": "n/a",
"identity": "rim"
} ],
"type": [ {
"code": "BackboneElement"
} ],
"extension": [ {
"url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status",
"valueCode": "normative"
}, {
"url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-normative-version",
"valueCode": "4.0.0"
} ],
"max": "*",
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.StrukturelleVariante",
"condition": [ "ele-1" ],
"base": {
"max": "*",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.StrukturelleVariante"
}
}, {
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.StrukturelleVariante.id",
"min": 0,
"definition": "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
"isModifier": false,
"short": "Unique id for inter-element referencing",
"mapping": [ {
"map": "n/a",
"identity": "rim"
} ],
"type": [ {
"code": "http://hl7.org/fhirpath/System.String",
"extension": [ {
"url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
"valueUrl": "string"
} ]
} ],
"representation": [ "xmlAttr" ],
"max": "1",
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.StrukturelleVariante.id",
"base": {
"max": "1",
"min": 0,
"path": "Element.id"
},
"isSummary": false
}, {
"constraint": [ {
"key": "ele-1",
"human": "All FHIR elements must have a @value or children",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element",
"severity": "error",
"expression": "hasValue() or (children().count() > id.count())"
}, {
"key": "ext-1",
"human": "Must have either extensions or value[x], not both",
"xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
"source": "http://hl7.org/fhir/StructureDefinition/Extension",
"severity": "error",
"expression": "extension.exists() != value.exists()"
} ],
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.StrukturelleVariante.extension",
"min": 0,
"definition": "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
"isModifier": false,
"short": "Additional content defined by implementations",
"mapping": [ {
"map": "n/a",
"identity": "rim"
} ],
"slicing": {
"rules": "open",
"description": "Extensions are always sliced by (at least) url",
"discriminator": [ {
"path": "url",
"type": "value"
} ]
},
"type": [ {
"code": "Extension"
} ],
"alias": [ "extensions", "user content" ],
"max": "*",
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.StrukturelleVariante.extension",
"comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
"base": {
"max": "*",
"min": 0,
"path": "Element.extension"
},
"isSummary": false
}, {
"constraint": [ {
"key": "ele-1",
"human": "All FHIR elements must have a @value or children",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element",
"severity": "error",
"expression": "hasValue() or (children().count() > id.count())"
}, {
"key": "ext-1",
"human": "Must have either extensions or value[x], not both",
"xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
"source": "http://hl7.org/fhir/StructureDefinition/Extension",
"severity": "error",
"expression": "extension.exists() != value.exists()"
} ],
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.StrukturelleVariante.modifierExtension",
"requirements": "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](extensibility.html#modifierExtension).",
"min": 0,
"definition": "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).",
"isModifier": true,
"short": "Extensions that cannot be ignored even if unrecognized",
"mapping": [ {
"map": "N/A",
"identity": "rim"
} ],
"type": [ {
"code": "Extension"
} ],
"alias": [ "extensions", "user content", "modifiers" ],
"max": "*",
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.StrukturelleVariante.modifierExtension",
"comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
"base": {
"max": "*",
"min": 0,
"path": "BackboneElement.modifierExtension"
},
"isModifierReason": "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them",
"isSummary": true
}, {
"constraint": [ {
"key": "ele-1",
"human": "All FHIR elements must have a @value or children",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element",
"severity": "error",
"expression": "hasValue() or (children().count() > id.count())"
} ],
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.StrukturelleVariante.Identifier",
"min": 0,
"definition": "interner Identifikator der Variante",
"isModifier": false,
"short": "Identifier",
"type": [ {
"code": "string"
} ],
"max": "1",
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.StrukturelleVariante.Identifier",
"comment": "Note that FHIR strings SHALL NOT exceed 1MB in size",
"base": {
"max": "1",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.StrukturelleVariante.Identifier"
},
"isSummary": false
}, {
"constraint": [ {
"key": "ele-1",
"human": "All FHIR elements must have a @value or children",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element",
"severity": "error",
"expression": "hasValue() or (children().count() > id.count())"
} ],
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.StrukturelleVariante.Quellprobe",
"min": 0,
"definition": "Art der Quellprobe (somatisch oder Keimbahn)",
"isModifier": false,
"short": "Art der Quellprobe",
"type": [ {
"code": "code"
} ],
"max": "1",
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.StrukturelleVariante.Quellprobe",
"base": {
"max": "1",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.StrukturelleVariante.Quellprobe"
},
"isSummary": false
}, {
"constraint": [ {
"key": "ele-1",
"human": "All FHIR elements must have a @value or children",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element",
"severity": "error",
"expression": "hasValue() or (children().count() > id.count())"
} ],
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.StrukturelleVariante.Gen",
"min": 0,
"definition": "N-terminales Gen",
"isModifier": false,
"short": "Gen",
"type": [ {
"code": "code"
} ],
"max": "1",
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.StrukturelleVariante.Gen",
"base": {
"max": "1",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.StrukturelleVariante.Gen"
},
"isSummary": false
}, {
"constraint": [ {
"key": "ele-1",
"human": "All FHIR elements must have a @value or children",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element",
"severity": "error",
"expression": "hasValue() or (children().count() > id.count())"
} ],
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.StrukturelleVariante.GenC",
"min": 0,
"definition": "C-terminales Gen, falls in-frame und kodierend",
"isModifier": false,
"short": "Gen",
"type": [ {
"code": "code"
} ],
"max": "1",
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.StrukturelleVariante.GenC",
"base": {
"max": "1",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.StrukturelleVariante.GenC"
},
"isSummary": false
}, {
"constraint": [ {
"key": "ele-1",
"human": "All FHIR elements must have a @value or children",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element",
"severity": "error",
"expression": "hasValue() or (children().count() > id.count())"
} ],
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.StrukturelleVariante.StrukturTyp",
"min": 0,
"definition": "Variantentyp (Inversion, Translokation, Deletion, Insertion, Duplikation)",
"isModifier": false,
"short": "Variantentyp",
"type": [ {
"code": "code"
} ],
"max": "1",
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.StrukturelleVariante.StrukturTyp",
"base": {
"max": "1",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.StrukturelleVariante.StrukturTyp"
},
"isSummary": false
}, {
"constraint": [ {
"key": "ele-1",
"human": "All FHIR elements must have a @value or children",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element",
"severity": "error",
"expression": "hasValue() or (children().count() > id.count())"
} ],
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.StrukturelleVariante.Beschreibung",
"min": 0,
"definition": "Beschreibung der Variante nach HGVS oder ISCN",
"isModifier": false,
"short": "Beschreibung der Variante",
"type": [ {
"code": "code"
} ],
"max": "1",
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.StrukturelleVariante.Beschreibung",
"base": {
"max": "1",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.StrukturelleVariante.Beschreibung"
},
"isSummary": false
}, {
"constraint": [ {
"key": "ele-1",
"human": "All FHIR elements must have a @value or children",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element",
"severity": "error",
"expression": "hasValue() or (children().count() > id.count())"
} ],
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.StrukturelleVariante.Nachweismethode",
"min": 0,
"definition": "Nachweismethode (DNA / RNA)",
"isModifier": false,
"short": "Nachweismethode",
"type": [ {
"code": "code"
} ],
"max": "1",
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.StrukturelleVariante.Nachweismethode",
"base": {
"max": "1",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.StrukturelleVariante.Nachweismethode"
},
"isSummary": false
}, {
"constraint": [ {
"key": "ele-1",
"human": "All FHIR elements must have a @value or children",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element",
"severity": "error",
"expression": "hasValue() or (children().count() > id.count())"
} ],
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.StrukturelleVariante.Lokalization",
"min": 0,
"definition": "Lokalisation im kodierenden, regulatorischen oder intergenischen Bereich",
"isModifier": false,
"short": "Lokalisation der Variante",
"type": [ {
"code": "code"
} ],
"max": "1",
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.StrukturelleVariante.Lokalization",
"base": {
"max": "1",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.StrukturelleVariante.Lokalization"
},
"isSummary": false
}, {
"constraint": [ {
"key": "ele-1",
"human": "All FHIR elements must have a @value or children",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element",
"severity": "error",
"expression": "hasValue() or (children().count() > id.count())"
} ],
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.ExpressionsVariante",
"min": 0,
"definition": "Expressionsvariante",
"isModifier": false,
"short": "Expressionsvariante",
"mapping": [ {
"map": "n/a",
"identity": "rim"
} ],
"type": [ {
"code": "BackboneElement"
} ],
"extension": [ {
"url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status",
"valueCode": "normative"
}, {
"url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-normative-version",
"valueCode": "4.0.0"
} ],
"max": "*",
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.ExpressionsVariante",
"condition": [ "ele-1" ],
"base": {
"max": "*",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.ExpressionsVariante"
}
}, {
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.ExpressionsVariante.id",
"min": 0,
"definition": "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
"isModifier": false,
"short": "Unique id for inter-element referencing",
"mapping": [ {
"map": "n/a",
"identity": "rim"
} ],
"type": [ {
"code": "http://hl7.org/fhirpath/System.String",
"extension": [ {
"url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
"valueUrl": "string"
} ]
} ],
"representation": [ "xmlAttr" ],
"max": "1",
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.ExpressionsVariante.id",
"base": {
"max": "1",
"min": 0,
"path": "Element.id"
},
"isSummary": false
}, {
"constraint": [ {
"key": "ele-1",
"human": "All FHIR elements must have a @value or children",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element",
"severity": "error",
"expression": "hasValue() or (children().count() > id.count())"
}, {
"key": "ext-1",
"human": "Must have either extensions or value[x], not both",
"xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
"source": "http://hl7.org/fhir/StructureDefinition/Extension",
"severity": "error",
"expression": "extension.exists() != value.exists()"
} ],
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.ExpressionsVariante.extension",
"min": 0,
"definition": "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
"isModifier": false,
"short": "Additional content defined by implementations",
"mapping": [ {
"map": "n/a",
"identity": "rim"
} ],
"slicing": {
"rules": "open",
"description": "Extensions are always sliced by (at least) url",
"discriminator": [ {
"path": "url",
"type": "value"
} ]
},
"type": [ {
"code": "Extension"
} ],
"alias": [ "extensions", "user content" ],
"max": "*",
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.ExpressionsVariante.extension",
"comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
"base": {
"max": "*",
"min": 0,
"path": "Element.extension"
},
"isSummary": false
}, {
"constraint": [ {
"key": "ele-1",
"human": "All FHIR elements must have a @value or children",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element",
"severity": "error",
"expression": "hasValue() or (children().count() > id.count())"
}, {
"key": "ext-1",
"human": "Must have either extensions or value[x], not both",
"xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
"source": "http://hl7.org/fhir/StructureDefinition/Extension",
"severity": "error",
"expression": "extension.exists() != value.exists()"
} ],
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.ExpressionsVariante.modifierExtension",
"requirements": "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](extensibility.html#modifierExtension).",
"min": 0,
"definition": "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).",
"isModifier": true,
"short": "Extensions that cannot be ignored even if unrecognized",
"mapping": [ {
"map": "N/A",
"identity": "rim"
} ],
"type": [ {
"code": "Extension"
} ],
"alias": [ "extensions", "user content", "modifiers" ],
"max": "*",
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.ExpressionsVariante.modifierExtension",
"comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
"base": {
"max": "*",
"min": 0,
"path": "BackboneElement.modifierExtension"
},
"isModifierReason": "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them",
"isSummary": true
}, {
"constraint": [ {
"key": "ele-1",
"human": "All FHIR elements must have a @value or children",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element",
"severity": "error",
"expression": "hasValue() or (children().count() > id.count())"
} ],
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.ExpressionsVariante.Identifier",
"min": 0,
"definition": "interner Identifikator der Variante",
"isModifier": false,
"short": "Identifier",
"type": [ {
"code": "string"
} ],
"max": "1",
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.ExpressionsVariante.Identifier",
"comment": "Note that FHIR strings SHALL NOT exceed 1MB in size",
"base": {
"max": "1",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.ExpressionsVariante.Identifier"
},
"isSummary": false
}, {
"constraint": [ {
"key": "ele-1",
"human": "All FHIR elements must have a @value or children",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element",
"severity": "error",
"expression": "hasValue() or (children().count() > id.count())"
} ],
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.ExpressionsVariante.Gen",
"min": 1,
"definition": "Gen kodiert nach HGNC",
"isModifier": false,
"short": "Gen",
"type": [ {
"code": "code"
} ],
"max": "1",
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.ExpressionsVariante.Gen",
"base": {
"max": "1",
"min": 1,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.ExpressionsVariante.Gen"
},
"isSummary": false
}, {
"constraint": [ {
"key": "ele-1",
"human": "All FHIR elements must have a @value or children",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element",
"severity": "error",
"expression": "hasValue() or (children().count() > id.count())"
} ],
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.ExpressionsVariante.Expression",
"min": 0,
"definition": "Expression des Gens (über- oder unterexprimiert)",
"isModifier": false,
"short": "Expression",
"type": [ {
"code": "code"
} ],
"max": "1",
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.ExpressionsVariante.Expression",
"base": {
"max": "1",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.ExpressionsVariante.Expression"
},
"isSummary": false
}, {
"constraint": [ {
"key": "ele-1",
"human": "All FHIR elements must have a @value or children",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element",
"severity": "error",
"expression": "hasValue() or (children().count() > id.count())"
} ],
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.ExpressionsVariante.Bewertungsgrundlage",
"min": 0,
"definition": "Bewertungsgrundlage der Expression (z.B. Vergleichskohorte von 400 Patienten)",
"isModifier": false,
"short": "Bewertungsgrundlage",
"type": [ {
"code": "string"
} ],
"max": "1",
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.ExpressionsVariante.Bewertungsgrundlage",
"comment": "Note that FHIR strings SHALL NOT exceed 1MB in size",
"base": {
"max": "1",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.ExpressionsVariante.Bewertungsgrundlage"
},
"isSummary": false
}, {
"constraint": [ {
"key": "ele-1",
"human": "All FHIR elements must have a @value or children",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element",
"severity": "error",
"expression": "hasValue() or (children().count() > id.count())"
} ],
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.ExpressionsVariante.TMB",
"min": 0,
"definition": "Tumor Mutational Burden (TMB) in Mut/Mb",
"isModifier": false,
"short": "Tumor Mutational Burden (TMB)",
"type": [ {
"code": "decimal"
} ],
"max": "1",
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.ExpressionsVariante.TMB",
"comment": "Do not use an IEEE type floating point type, instead use something that works like a true decimal, with inbuilt precision (e.g. Java BigInteger)",
"base": {
"max": "1",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.ExpressionsVariante.TMB"
},
"isSummary": false
}, {
"constraint": [ {
"key": "ele-1",
"human": "All FHIR elements must have a @value or children",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element",
"severity": "error",
"expression": "hasValue() or (children().count() > id.count())"
} ],
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.ExpressionsVariante.HRD",
"min": 0,
"definition": "Homologous Recombination Deficiency (HRD) erhöht ja/nein",
"isModifier": false,
"short": "Homologous Recombination Deficiency (HRD)",
"type": [ {
"code": "code"
} ],
"max": "1",
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.ExpressionsVariante.HRD",
"base": {
"max": "1",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.ExpressionsVariante.HRD"
},
"isSummary": false
}, {
"constraint": [ {
"key": "ele-1",
"human": "All FHIR elements must have a @value or children",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element",
"severity": "error",
"expression": "hasValue() or (children().count() > id.count())"
} ],
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.ExpressionsVariante.LST",
"min": 0,
"definition": "Large Scale Transition (LST) erhöht ja/nein",
"isModifier": false,
"short": "Large Scale Transition (LST)",
"type": [ {
"code": "code"
} ],
"max": "1",
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.ExpressionsVariante.LST",
"base": {
"max": "1",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.ExpressionsVariante.LST"
},
"isSummary": false
}, {
"constraint": [ {
"key": "ele-1",
"human": "All FHIR elements must have a @value or children",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element",
"severity": "error",
"expression": "hasValue() or (children().count() > id.count())"
} ],
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.ExpressionsVariante.TAI",
"min": 0,
"definition": "Telomeric Allelic Imbalance (TAI) erhöht ja/nein",
"isModifier": false,
"short": "Telomeric Allelic Imbalance (TAI)",
"type": [ {
"code": "code"
} ],
"max": "1",
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.ExpressionsVariante.TAI",
"base": {
"max": "1",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.ExpressionsVariante.TAI"
},
"isSummary": false
}, {
"constraint": [ {
"key": "ele-1",
"human": "All FHIR elements must have a @value or children",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element",
"severity": "error",
"expression": "hasValue() or (children().count() > id.count())"
} ],
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.ExpressionsVariante.SBS",
"min": 0,
"definition": "Single Base Substitution (SBS) erhöht ja/nein",
"isModifier": false,
"short": "Single Base Substitution (SBS)",
"type": [ {
"code": "code"
} ],
"max": "1",
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.ExpressionsVariante.SBS",
"base": {
"max": "1",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.ExpressionsVariante.SBS"
},
"isSummary": false
}, {
"constraint": [ {
"key": "ele-1",
"human": "All FHIR elements must have a @value or children",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element",
"severity": "error",
"expression": "hasValue() or (children().count() > id.count())"
} ],
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.ExpressionsVariante.SBSSignature",
"min": 0,
"definition": "Single Base Substitution Signature",
"isModifier": false,
"short": "Single Base Substitution Signature",
"type": [ {
"code": "code"
} ],
"max": "1",
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.ExpressionsVariante.SBSSignature",
"base": {
"max": "1",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.ExpressionsVariante.SBSSignature"
},
"isSummary": false
}, {
"constraint": [ {
"key": "ele-1",
"human": "All FHIR elements must have a @value or children",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element",
"severity": "error",
"expression": "hasValue() or (children().count() > id.count())"
} ],
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.ExpressionsVariante.Lokalization",
"min": 0,
"definition": "Lokalisation im kodierenden, regulatorischen oder intergenischen Bereich",
"isModifier": false,
"short": "Lokalisation der Variante",
"type": [ {
"code": "code"
} ],
"max": "1",
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.ExpressionsVariante.Lokalization",
"base": {
"max": "1",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.ExpressionsVariante.Lokalization"
},
"isSummary": false
}, {
"constraint": [ {
"key": "ele-1",
"human": "All FHIR elements must have a @value or children",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element",
"severity": "error",
"expression": "hasValue() or (children().count() > id.count())"
} ],
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan",
"min": 0,
"definition": "Therapieplan",
"isModifier": false,
"short": "Therapieplan",
"mapping": [ {
"map": "n/a",
"identity": "rim"
} ],
"type": [ {
"code": "BackboneElement"
} ],
"extension": [ {
"url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status",
"valueCode": "normative"
}, {
"url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-normative-version",
"valueCode": "4.0.0"
} ],
"max": "*",
"id": "mii-lm-mvgenomseq-onkologie.OnkologiePlan",
"condition": [ "ele-1" ],
"base": {
"max": "*",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan"
}
}, {
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.id",
"min": 0,
"definition": "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
"isModifier": false,
"short": "Unique id for inter-element referencing",
"mapping": [ {
"map": "n/a",
"identity": "rim"
} ],
"type": [ {
"code": "http://hl7.org/fhirpath/System.String",
"extension": [ {
"url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
"valueUrl": "string"
} ]
} ],
"representation": [ "xmlAttr" ],
"max": "1",
"id": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.id",
"base": {
"max": "1",
"min": 0,
"path": "Element.id"
},
"isSummary": false
}, {
"constraint": [ {
"key": "ele-1",
"human": "All FHIR elements must have a @value or children",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element",
"severity": "error",
"expression": "hasValue() or (children().count() > id.count())"
}, {
"key": "ext-1",
"human": "Must have either extensions or value[x], not both",
"xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
"source": "http://hl7.org/fhir/StructureDefinition/Extension",
"severity": "error",
"expression": "extension.exists() != value.exists()"
} ],
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.extension",
"min": 0,
"definition": "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
"isModifier": false,
"short": "Additional content defined by implementations",
"mapping": [ {
"map": "n/a",
"identity": "rim"
} ],
"slicing": {
"rules": "open",
"description": "Extensions are always sliced by (at least) url",
"discriminator": [ {
"path": "url",
"type": "value"
} ]
},
"type": [ {
"code": "Extension"
} ],
"alias": [ "extensions", "user content" ],
"max": "*",
"id": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.extension",
"comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
"base": {
"max": "*",
"min": 0,
"path": "Element.extension"
},
"isSummary": false
}, {
"constraint": [ {
"key": "ele-1",
"human": "All FHIR elements must have a @value or children",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element",
"severity": "error",
"expression": "hasValue() or (children().count() > id.count())"
}, {
"key": "ext-1",
"human": "Must have either extensions or value[x], not both",
"xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
"source": "http://hl7.org/fhir/StructureDefinition/Extension",
"severity": "error",
"expression": "extension.exists() != value.exists()"
} ],
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.modifierExtension",
"requirements": "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](extensibility.html#modifierExtension).",
"min": 0,
"definition": "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).",
"isModifier": true,
"short": "Extensions that cannot be ignored even if unrecognized",
"mapping": [ {
"map": "N/A",
"identity": "rim"
} ],
"type": [ {
"code": "Extension"
} ],
"alias": [ "extensions", "user content", "modifiers" ],
"max": "*",
"id": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.modifierExtension",
"comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
"base": {
"max": "*",
"min": 0,
"path": "BackboneElement.modifierExtension"
},
"isModifierReason": "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them",
"isSummary": true
}, {
"constraint": [ {
"key": "ele-1",
"human": "All FHIR elements must have a @value or children",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element",
"severity": "error",
"expression": "hasValue() or (children().count() > id.count())"
} ],
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.MolekularesTumorboard",
"min": 0,
"definition": "Molekulares Tumorboard",
"isModifier": false,
"short": "Molekulares Tumorboard",
"mapping": [ {
"map": "n/a",
"identity": "rim"
} ],
"type": [ {
"code": "BackboneElement"
} ],
"extension": [ {
"url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status",
"valueCode": "normative"
}, {
"url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-normative-version",
"valueCode": "4.0.0"
} ],
"max": "*",
"id": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.MolekularesTumorboard",
"condition": [ "ele-1" ],
"base": {
"max": "*",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.MolekularesTumorboard"
}
}, {
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.MolekularesTumorboard.id",
"min": 0,
"definition": "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
"isModifier": false,
"short": "Unique id for inter-element referencing",
"mapping": [ {
"map": "n/a",
"identity": "rim"
} ],
"type": [ {
"code": "http://hl7.org/fhirpath/System.String",
"extension": [ {
"url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
"valueUrl": "string"
} ]
} ],
"representation": [ "xmlAttr" ],
"max": "1",
"id": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.MolekularesTumorboard.id",
"base": {
"max": "1",
"min": 0,
"path": "Element.id"
},
"isSummary": false
}, {
"constraint": [ {
"key": "ele-1",
"human": "All FHIR elements must have a @value or children",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element",
"severity": "error",
"expression": "hasValue() or (children().count() > id.count())"
}, {
"key": "ext-1",
"human": "Must have either extensions or value[x], not both",
"xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
"source": "http://hl7.org/fhir/StructureDefinition/Extension",
"severity": "error",
"expression": "extension.exists() != value.exists()"
} ],
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.MolekularesTumorboard.extension",
"min": 0,
"definition": "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
"isModifier": false,
"short": "Additional content defined by implementations",
"mapping": [ {
"map": "n/a",
"identity": "rim"
} ],
"slicing": {
"rules": "open",
"description": "Extensions are always sliced by (at least) url",
"discriminator": [ {
"path": "url",
"type": "value"
} ]
},
"type": [ {
"code": "Extension"
} ],
"alias": [ "extensions", "user content" ],
"max": "*",
"id": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.MolekularesTumorboard.extension",
"comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
"base": {
"max": "*",
"min": 0,
"path": "Element.extension"
},
"isSummary": false
}, {
"constraint": [ {
"key": "ele-1",
"human": "All FHIR elements must have a @value or children",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element",
"severity": "error",
"expression": "hasValue() or (children().count() > id.count())"
}, {
"key": "ext-1",
"human": "Must have either extensions or value[x], not both",
"xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
"source": "http://hl7.org/fhir/StructureDefinition/Extension",
"severity": "error",
"expression": "extension.exists() != value.exists()"
} ],
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.MolekularesTumorboard.modifierExtension",
"requirements": "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](extensibility.html#modifierExtension).",
"min": 0,
"definition": "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).",
"isModifier": true,
"short": "Extensions that cannot be ignored even if unrecognized",
"mapping": [ {
"map": "N/A",
"identity": "rim"
} ],
"type": [ {
"code": "Extension"
} ],
"alias": [ "extensions", "user content", "modifiers" ],
"max": "*",
"id": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.MolekularesTumorboard.modifierExtension",
"comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
"base": {
"max": "*",
"min": 0,
"path": "BackboneElement.modifierExtension"
},
"isModifierReason": "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them",
"isSummary": true
}, {
"constraint": [ {
"key": "ele-1",
"human": "All FHIR elements must have a @value or children",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element",
"severity": "error",
"expression": "hasValue() or (children().count() > id.count())"
} ],
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.MolekularesTumorboard.Datum",
"min": 1,
"definition": "Datum des Tumorboards",
"isModifier": false,
"short": "Datum",
"type": [ {
"code": "date"
} ],
"max": "1",
"id": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.MolekularesTumorboard.Datum",
"base": {
"max": "1",
"min": 1,
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.MolekularesTumorboard.Datum"
},
"isSummary": false
}, {
"constraint": [ {
"key": "ele-1",
"human": "All FHIR elements must have a @value or children",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element",
"severity": "error",
"expression": "hasValue() or (children().count() > id.count())"
} ],
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.MolekularesTumorboard.EmpfehlungStudie",
"min": 0,
"definition": "Empfehlung zur Studienteilnahme ja/nein",
"isModifier": false,
"short": "Empfehlung Studie",
"type": [ {
"code": "code"
} ],
"max": "1",
"id": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.MolekularesTumorboard.EmpfehlungStudie",
"base": {
"max": "1",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.MolekularesTumorboard.EmpfehlungStudie"
},
"isSummary": false
}, {
"constraint": [ {
"key": "ele-1",
"human": "All FHIR elements must have a @value or children",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element",
"severity": "error",
"expression": "hasValue() or (children().count() > id.count())"
} ],
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.MolekularesTumorboard.EmpfehlungBeratung",
"min": 0,
"definition": "Empfehlung zu einer humangenetischen Beratung ja/nein",
"isModifier": false,
"short": "Empfehlung humangenetische Beratung",
"type": [ {
"code": "code"
} ],
"max": "1",
"id": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.MolekularesTumorboard.EmpfehlungBeratung",
"base": {
"max": "1",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.MolekularesTumorboard.EmpfehlungBeratung"
},
"isSummary": false
}, {
"constraint": [ {
"key": "ele-1",
"human": "All FHIR elements must have a @value or children",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element",
"severity": "error",
"expression": "hasValue() or (children().count() > id.count())"
} ],
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.MolekularesTumorboard.EmpfehlungReevaluation",
"min": 0,
"definition": "Empfehlung zur Reevaluation der molekularen Diagnostik ja/nein",
"isModifier": false,
"short": "Empfehlung Reevaluation",
"type": [ {
"code": "code"
} ],
"max": "1",
"id": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.MolekularesTumorboard.EmpfehlungReevaluation",
"base": {
"max": "1",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.MolekularesTumorboard.EmpfehlungReevaluation"
},
"isSummary": false
}, {
"constraint": [ {
"key": "ele-1",
"human": "All FHIR elements must have a @value or children",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element",
"severity": "error",
"expression": "hasValue() or (children().count() > id.count())"
} ],
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.MolekularesTumorboard.EmpfehlungOperation",
"min": 0,
"definition": "Empfehlung zur Operation ja/nein",
"isModifier": false,
"short": "Empfehlung Operation",
"type": [ {
"code": "code"
} ],
"max": "1",
"id": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.MolekularesTumorboard.EmpfehlungOperation",
"base": {
"max": "1",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.MolekularesTumorboard.EmpfehlungOperation"
},
"isSummary": false
}, {
"constraint": [ {
"key": "ele-1",
"human": "All FHIR elements must have a @value or children",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element",
"severity": "error",
"expression": "hasValue() or (children().count() > id.count())"
} ],
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.MolekularesTumorboard.EmpfehlungOperationArt",
"min": 0,
"definition": "empfohlenen Operation",
"isModifier": false,
"short": "empfohlenene Operation",
"type": [ {
"code": "code"
} ],
"max": "1",
"id": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.MolekularesTumorboard.EmpfehlungOperationArt",
"base": {
"max": "1",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.MolekularesTumorboard.EmpfehlungOperationArt"
},
"isSummary": false
}, {
"constraint": [ {
"key": "ele-1",
"human": "All FHIR elements must have a @value or children",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element",
"severity": "error",
"expression": "hasValue() or (children().count() > id.count())"
} ],
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.MolekularesTumorboard.EmpfehlungOperationRisikoreduzierend",
"min": 0,
"definition": "empfohlenen Operation ist riskoreduzierend ja/nein",
"isModifier": false,
"short": "empfohlene Operation ist riskoreduzierend",
"type": [ {
"code": "code"
} ],
"max": "1",
"id": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.MolekularesTumorboard.EmpfehlungOperationRisikoreduzierend",
"base": {
"max": "1",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.MolekularesTumorboard.EmpfehlungOperationRisikoreduzierend"
},
"isSummary": false
}, {
"constraint": [ {
"key": "ele-1",
"human": "All FHIR elements must have a @value or children",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element",
"severity": "error",
"expression": "hasValue() or (children().count() > id.count())"
} ],
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.MolekularesTumorboard.EmpfehlungOperationTherapeutisch",
"min": 0,
"definition": "empfohlenene Operation ist therapeutisch ja/nein",
"isModifier": false,
"short": "empfohlene Operation ist therapeutisch",
"type": [ {
"code": "code"
} ],
"max": "1",
"id": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.MolekularesTumorboard.EmpfehlungOperationTherapeutisch",
"base": {
"max": "1",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.MolekularesTumorboard.EmpfehlungOperationTherapeutisch"
},
"isSummary": false
}, {
"constraint": [ {
"key": "ele-1",
"human": "All FHIR elements must have a @value or children",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element",
"severity": "error",
"expression": "hasValue() or (children().count() > id.count())"
} ],
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.MolekularesTumorboard.DurchgefuehrteOperation",
"min": 0,
"definition": "Durchgeführte Operation nach OPS inkl. Version",
"isModifier": false,
"short": "Durchgeführte Operation",
"type": [ {
"code": "code"
} ],
"max": "*",
"id": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.MolekularesTumorboard.DurchgefuehrteOperation",
"base": {
"max": "*",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.MolekularesTumorboard.DurchgefuehrteOperation"
},
"isSummary": false
}, {
"constraint": [ {
"key": "ele-1",
"human": "All FHIR elements must have a @value or children",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element",
"severity": "error",
"expression": "hasValue() or (children().count() > id.count())"
} ],
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.EmpfohleneStudie",
"min": 0,
"definition": "Empfohlene Studieneinschlüsse",
"isModifier": false,
"short": "Empfohlene Studieneinschlüsse",
"mapping": [ {
"map": "n/a",
"identity": "rim"
} ],
"type": [ {
"code": "BackboneElement"
} ],
"extension": [ {
"url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status",
"valueCode": "normative"
}, {
"url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-normative-version",
"valueCode": "4.0.0"
} ],
"max": "*",
"id": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.EmpfohleneStudie",
"condition": [ "ele-1" ],
"base": {
"max": "*",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.EmpfohleneStudie"
}
}, {
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.EmpfohleneStudie.id",
"min": 0,
"definition": "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
"isModifier": false,
"short": "Unique id for inter-element referencing",
"mapping": [ {
"map": "n/a",
"identity": "rim"
} ],
"type": [ {
"code": "http://hl7.org/fhirpath/System.String",
"extension": [ {
"url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
"valueUrl": "string"
} ]
} ],
"representation": [ "xmlAttr" ],
"max": "1",
"id": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.EmpfohleneStudie.id",
"base": {
"max": "1",
"min": 0,
"path": "Element.id"
},
"isSummary": false
}, {
"constraint": [ {
"key": "ele-1",
"human": "All FHIR elements must have a @value or children",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element",
"severity": "error",
"expression": "hasValue() or (children().count() > id.count())"
}, {
"key": "ext-1",
"human": "Must have either extensions or value[x], not both",
"xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
"source": "http://hl7.org/fhir/StructureDefinition/Extension",
"severity": "error",
"expression": "extension.exists() != value.exists()"
} ],
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.EmpfohleneStudie.extension",
"min": 0,
"definition": "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
"isModifier": false,
"short": "Additional content defined by implementations",
"mapping": [ {
"map": "n/a",
"identity": "rim"
} ],
"slicing": {
"rules": "open",
"description": "Extensions are always sliced by (at least) url",
"discriminator": [ {
"path": "url",
"type": "value"
} ]
},
"type": [ {
"code": "Extension"
} ],
"alias": [ "extensions", "user content" ],
"max": "*",
"id": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.EmpfohleneStudie.extension",
"comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
"base": {
"max": "*",
"min": 0,
"path": "Element.extension"
},
"isSummary": false
}, {
"constraint": [ {
"key": "ele-1",
"human": "All FHIR elements must have a @value or children",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element",
"severity": "error",
"expression": "hasValue() or (children().count() > id.count())"
}, {
"key": "ext-1",
"human": "Must have either extensions or value[x], not both",
"xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
"source": "http://hl7.org/fhir/StructureDefinition/Extension",
"severity": "error",
"expression": "extension.exists() != value.exists()"
} ],
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.EmpfohleneStudie.modifierExtension",
"requirements": "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](extensibility.html#modifierExtension).",
"min": 0,
"definition": "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).",
"isModifier": true,
"short": "Extensions that cannot be ignored even if unrecognized",
"mapping": [ {
"map": "N/A",
"identity": "rim"
} ],
"type": [ {
"code": "Extension"
} ],
"alias": [ "extensions", "user content", "modifiers" ],
"max": "*",
"id": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.EmpfohleneStudie.modifierExtension",
"comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
"base": {
"max": "*",
"min": 0,
"path": "BackboneElement.modifierExtension"
},
"isModifierReason": "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them",
"isSummary": true
}, {
"constraint": [ {
"key": "ele-1",
"human": "All FHIR elements must have a @value or children",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element",
"severity": "error",
"expression": "hasValue() or (children().count() > id.count())"
} ],
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.EmpfohleneStudie.Identifier",
"min": 0,
"definition": "interner Identifikator der Studie",
"isModifier": false,
"short": "Identifier",
"type": [ {
"code": "string"
} ],
"max": "1",
"id": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.EmpfohleneStudie.Identifier",
"comment": "Note that FHIR strings SHALL NOT exceed 1MB in size",
"base": {
"max": "1",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.EmpfohleneStudie.Identifier"
},
"isSummary": false
}, {
"constraint": [ {
"key": "ele-1",
"human": "All FHIR elements must have a @value or children",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element",
"severity": "error",
"expression": "hasValue() or (children().count() > id.count())"
} ],
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.EmpfohleneStudie.Register",
"min": 0,
"definition": "Registersystematik, in dem die StudienID angegeben wird (NCT, EudraCT/CTIS, DRKS, andere, unbekannt)",
"isModifier": false,
"short": "Register",
"type": [ {
"code": "code"
} ],
"max": "1",
"id": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.EmpfohleneStudie.Register",
"base": {
"max": "1",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.EmpfohleneStudie.Register"
},
"isSummary": false
}, {
"constraint": [ {
"key": "ele-1",
"human": "All FHIR elements must have a @value or children",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element",
"severity": "error",
"expression": "hasValue() or (children().count() > id.count())"
} ],
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.EmpfohleneStudie.StudienID",
"min": 0,
"definition": "StudienID in einer Registersystematik",
"isModifier": false,
"short": "Studie",
"type": [ {
"code": "code"
} ],
"max": "1",
"id": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.EmpfohleneStudie.StudienID",
"base": {
"max": "1",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.EmpfohleneStudie.StudienID"
},
"isSummary": false
}, {
"constraint": [ {
"key": "ele-1",
"human": "All FHIR elements must have a @value or children",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element",
"severity": "error",
"expression": "hasValue() or (children().count() > id.count())"
} ],
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.EmpfohleneStudie.Studienname",
"min": 1,
"definition": "Name der Studie",
"isModifier": false,
"short": "Name der Studie",
"type": [ {
"code": "string"
} ],
"max": "1",
"id": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.EmpfohleneStudie.Studienname",
"comment": "Note that FHIR strings SHALL NOT exceed 1MB in size",
"base": {
"max": "1",
"min": 1,
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.EmpfohleneStudie.Studienname"
},
"isSummary": false
}, {
"constraint": [ {
"key": "ele-1",
"human": "All FHIR elements must have a @value or children",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element",
"severity": "error",
"expression": "hasValue() or (children().count() > id.count())"
} ],
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.EmpfohleneStudie.Substanzen",
"min": 0,
"definition": "Substanzen, die in der Studie eingesetzt werden, nach ATC kodiert",
"isModifier": false,
"short": "Substanzen",
"type": [ {
"code": "code"
} ],
"max": "*",
"id": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.EmpfohleneStudie.Substanzen",
"base": {
"max": "*",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.EmpfohleneStudie.Substanzen"
},
"isSummary": false
}, {
"constraint": [ {
"key": "ele-1",
"human": "All FHIR elements must have a @value or children",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element",
"severity": "error",
"expression": "hasValue() or (children().count() > id.count())"
} ],
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.EmpfohleneStudie.Evidenzgrad",
"min": 0,
"definition": "Evidenzgrad",
"isModifier": false,
"short": "Evidenzgrad",
"type": [ {
"code": "code"
} ],
"max": "1",
"id": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.EmpfohleneStudie.Evidenzgrad",
"base": {
"max": "1",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.EmpfohleneStudie.Evidenzgrad"
},
"isSummary": false
}, {
"constraint": [ {
"key": "ele-1",
"human": "All FHIR elements must have a @value or children",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element",
"severity": "error",
"expression": "hasValue() or (children().count() > id.count())"
} ],
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.EmpfohleneStudie.ZusatzverweiseEvidenzgraduierung",
"min": 0,
"definition": "Zusatzverweise zur Evidenzgraduierung",
"isModifier": false,
"short": "Zusatzverweise zur Evidenzgraduierung",
"type": [ {
"code": "string"
} ],
"max": "*",
"id": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.EmpfohleneStudie.ZusatzverweiseEvidenzgraduierung",
"comment": "Note that FHIR strings SHALL NOT exceed 1MB in size",
"base": {
"max": "*",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.EmpfohleneStudie.ZusatzverweiseEvidenzgraduierung"
},
"isSummary": false
}, {
"constraint": [ {
"key": "ele-1",
"human": "All FHIR elements must have a @value or children",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element",
"severity": "error",
"expression": "hasValue() or (children().count() > id.count())"
} ],
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.EmpfohleneStudie.Prioritaet",
"min": 0,
"definition": "Priorität der Studie, falls mehrere Studien empfohlen wurde. 1 ist höchste Priorität",
"isModifier": false,
"short": "Priorität",
"type": [ {
"code": "code"
} ],
"max": "1",
"id": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.EmpfohleneStudie.Prioritaet",
"base": {
"max": "1",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.EmpfohleneStudie.Prioritaet"
},
"isSummary": false
}, {
"constraint": [ {
"key": "ele-1",
"human": "All FHIR elements must have a @value or children",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element",
"severity": "error",
"expression": "hasValue() or (children().count() > id.count())"
} ],
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.EmpfohleneStudie.Variante",
"min": 0,
"definition": "interne VariantenID der Variante, die für die Studie relevant ist",
"isModifier": false,
"short": "Variante",
"type": [ {
"code": "code"
} ],
"max": "*",
"id": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.EmpfohleneStudie.Variante",
"base": {
"max": "*",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.EmpfohleneStudie.Variante"
},
"isSummary": false
}, {
"constraint": [ {
"key": "ele-1",
"human": "All FHIR elements must have a @value or children",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element",
"severity": "error",
"expression": "hasValue() or (children().count() > id.count())"
} ],
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.Therapieempfehlung",
"min": 0,
"definition": "String",
"isModifier": false,
"short": "String",
"mapping": [ {
"map": "n/a",
"identity": "rim"
} ],
"type": [ {
"code": "BackboneElement"
} ],
"extension": [ {
"url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status",
"valueCode": "normative"
}, {
"url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-normative-version",
"valueCode": "4.0.0"
} ],
"max": "*",
"id": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.Therapieempfehlung",
"condition": [ "ele-1" ],
"base": {
"max": "*",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.Therapieempfehlung"
}
}, {
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.Therapieempfehlung.id",
"min": 0,
"definition": "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
"isModifier": false,
"short": "Unique id for inter-element referencing",
"mapping": [ {
"map": "n/a",
"identity": "rim"
} ],
"type": [ {
"code": "http://hl7.org/fhirpath/System.String",
"extension": [ {
"url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
"valueUrl": "string"
} ]
} ],
"representation": [ "xmlAttr" ],
"max": "1",
"id": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.Therapieempfehlung.id",
"base": {
"max": "1",
"min": 0,
"path": "Element.id"
},
"isSummary": false
}, {
"constraint": [ {
"key": "ele-1",
"human": "All FHIR elements must have a @value or children",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element",
"severity": "error",
"expression": "hasValue() or (children().count() > id.count())"
}, {
"key": "ext-1",
"human": "Must have either extensions or value[x], not both",
"xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
"source": "http://hl7.org/fhir/StructureDefinition/Extension",
"severity": "error",
"expression": "extension.exists() != value.exists()"
} ],
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.Therapieempfehlung.extension",
"min": 0,
"definition": "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
"isModifier": false,
"short": "Additional content defined by implementations",
"mapping": [ {
"map": "n/a",
"identity": "rim"
} ],
"slicing": {
"rules": "open",
"description": "Extensions are always sliced by (at least) url",
"discriminator": [ {
"path": "url",
"type": "value"
} ]
},
"type": [ {
"code": "Extension"
} ],
"alias": [ "extensions", "user content" ],
"max": "*",
"id": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.Therapieempfehlung.extension",
"comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
"base": {
"max": "*",
"min": 0,
"path": "Element.extension"
},
"isSummary": false
}, {
"constraint": [ {
"key": "ele-1",
"human": "All FHIR elements must have a @value or children",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element",
"severity": "error",
"expression": "hasValue() or (children().count() > id.count())"
}, {
"key": "ext-1",
"human": "Must have either extensions or value[x], not both",
"xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
"source": "http://hl7.org/fhir/StructureDefinition/Extension",
"severity": "error",
"expression": "extension.exists() != value.exists()"
} ],
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.Therapieempfehlung.modifierExtension",
"requirements": "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](extensibility.html#modifierExtension).",
"min": 0,
"definition": "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).",
"isModifier": true,
"short": "Extensions that cannot be ignored even if unrecognized",
"mapping": [ {
"map": "N/A",
"identity": "rim"
} ],
"type": [ {
"code": "Extension"
} ],
"alias": [ "extensions", "user content", "modifiers" ],
"max": "*",
"id": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.Therapieempfehlung.modifierExtension",
"comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
"base": {
"max": "*",
"min": 0,
"path": "BackboneElement.modifierExtension"
},
"isModifierReason": "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them",
"isSummary": true
}, {
"constraint": [ {
"key": "ele-1",
"human": "All FHIR elements must have a @value or children",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element",
"severity": "error",
"expression": "hasValue() or (children().count() > id.count())"
} ],
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.Therapieempfehlung.Identifier",
"min": 0,
"definition": "interner Identifikator der Therapieempfehlung",
"isModifier": false,
"short": "Identifier",
"type": [ {
"code": "string"
} ],
"max": "1",
"id": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.Therapieempfehlung.Identifier",
"comment": "Note that FHIR strings SHALL NOT exceed 1MB in size",
"base": {
"max": "1",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.Therapieempfehlung.Identifier"
},
"isSummary": false
}, {
"constraint": [ {
"key": "ele-1",
"human": "All FHIR elements must have a @value or children",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element",
"severity": "error",
"expression": "hasValue() or (children().count() > id.count())"
} ],
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.Therapieempfehlung.EmpfehlungTyp",
"min": 0,
"definition": "Typ der Empfehlung (z.B. inlabel, offlabel, compassionate use, unknown, secondary preventive)",
"isModifier": false,
"short": "Typ der Empfehlung",
"type": [ {
"code": "code"
} ],
"max": "1",
"id": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.Therapieempfehlung.EmpfehlungTyp",
"base": {
"max": "1",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.Therapieempfehlung.EmpfehlungTyp"
},
"isSummary": false
}, {
"constraint": [ {
"key": "ele-1",
"human": "All FHIR elements must have a @value or children",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element",
"severity": "error",
"expression": "hasValue() or (children().count() > id.count())"
} ],
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.Therapieempfehlung.Substanz",
"min": 0,
"definition": "Substanzen, die empfohlen werden, nach ATC kodiert",
"isModifier": false,
"short": "Substanzen",
"type": [ {
"code": "code"
} ],
"max": "*",
"id": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.Therapieempfehlung.Substanz",
"base": {
"max": "*",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.Therapieempfehlung.Substanz"
},
"isSummary": false
}, {
"constraint": [ {
"key": "ele-1",
"human": "All FHIR elements must have a @value or children",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element",
"severity": "error",
"expression": "hasValue() or (children().count() > id.count())"
} ],
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.Therapieempfehlung.Evidenzgrad",
"min": 0,
"definition": "Evidenzgrad (m1A - m4, unbekannt)",
"isModifier": false,
"short": "Evidenzgrad",
"type": [ {
"code": "code"
} ],
"max": "1",
"id": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.Therapieempfehlung.Evidenzgrad",
"base": {
"max": "1",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.Therapieempfehlung.Evidenzgrad"
},
"isSummary": false
}, {
"constraint": [ {
"key": "ele-1",
"human": "All FHIR elements must have a @value or children",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element",
"severity": "error",
"expression": "hasValue() or (children().count() > id.count())"
} ],
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.Therapieempfehlung.Prioritaet",
"min": 0,
"definition": "Priorität der Therapieempfehlung, falls mehrere Empfehlungen gegeben wurden. 1 ist höchste Priorität",
"isModifier": false,
"short": "Priorität",
"type": [ {
"code": "code"
} ],
"max": "1",
"id": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.Therapieempfehlung.Prioritaet",
"base": {
"max": "1",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.Therapieempfehlung.Prioritaet"
},
"isSummary": false
}, {
"constraint": [ {
"key": "ele-1",
"human": "All FHIR elements must have a @value or children",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element",
"severity": "error",
"expression": "hasValue() or (children().count() > id.count())"
} ],
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.Therapieempfehlung.Variante",
"min": 0,
"definition": "interne VariantenID der Variante, die für die Therapieempfehlung relevant ist",
"isModifier": false,
"short": "Variante",
"type": [ {
"code": "code"
} ],
"max": "*",
"id": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.Therapieempfehlung.Variante",
"base": {
"max": "*",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.Therapieempfehlung.Variante"
},
"isSummary": false
}, {
"constraint": [ {
"key": "ele-1",
"human": "All FHIR elements must have a @value or children",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element",
"severity": "error",
"expression": "hasValue() or (children().count() > id.count())"
} ],
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.Therapieempfehlung.TherapeutischeStrategie",
"min": 0,
"definition": "Therapeutische Strategie (z.B. zielgerichtete Therapie, Immuntherapie, Chemotherapie, supportive Therapie)",
"isModifier": false,
"short": "Therapeutische Strategie",
"type": [ {
"code": "code"
} ],
"max": "1",
"id": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.Therapieempfehlung.TherapeutischeStrategie",
"base": {
"max": "1",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.Therapieempfehlung.TherapeutischeStrategie"
},
"isSummary": false
}, {
"constraint": [ {
"key": "ele-1",
"human": "All FHIR elements must have a @value or children",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element",
"severity": "error",
"expression": "hasValue() or (children().count() > id.count())"
} ],
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.PraeventiveUntersuchungen",
"min": 0,
"definition": "Präventive Maßnahmen",
"isModifier": false,
"short": "Präventive Maßnahmen",
"mapping": [ {
"map": "n/a",
"identity": "rim"
} ],
"type": [ {
"code": "BackboneElement"
} ],
"extension": [ {
"url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status",
"valueCode": "normative"
}, {
"url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-normative-version",
"valueCode": "4.0.0"
} ],
"max": "*",
"id": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.PraeventiveUntersuchungen",
"condition": [ "ele-1" ],
"base": {
"max": "*",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.PraeventiveUntersuchungen"
}
}, {
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.PraeventiveUntersuchungen.id",
"min": 0,
"definition": "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
"isModifier": false,
"short": "Unique id for inter-element referencing",
"mapping": [ {
"map": "n/a",
"identity": "rim"
} ],
"type": [ {
"code": "http://hl7.org/fhirpath/System.String",
"extension": [ {
"url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
"valueUrl": "string"
} ]
} ],
"representation": [ "xmlAttr" ],
"max": "1",
"id": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.PraeventiveUntersuchungen.id",
"base": {
"max": "1",
"min": 0,
"path": "Element.id"
},
"isSummary": false
}, {
"constraint": [ {
"key": "ele-1",
"human": "All FHIR elements must have a @value or children",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element",
"severity": "error",
"expression": "hasValue() or (children().count() > id.count())"
}, {
"key": "ext-1",
"human": "Must have either extensions or value[x], not both",
"xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
"source": "http://hl7.org/fhir/StructureDefinition/Extension",
"severity": "error",
"expression": "extension.exists() != value.exists()"
} ],
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.PraeventiveUntersuchungen.extension",
"min": 0,
"definition": "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
"isModifier": false,
"short": "Additional content defined by implementations",
"mapping": [ {
"map": "n/a",
"identity": "rim"
} ],
"slicing": {
"rules": "open",
"description": "Extensions are always sliced by (at least) url",
"discriminator": [ {
"path": "url",
"type": "value"
} ]
},
"type": [ {
"code": "Extension"
} ],
"alias": [ "extensions", "user content" ],
"max": "*",
"id": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.PraeventiveUntersuchungen.extension",
"comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
"base": {
"max": "*",
"min": 0,
"path": "Element.extension"
},
"isSummary": false
}, {
"constraint": [ {
"key": "ele-1",
"human": "All FHIR elements must have a @value or children",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element",
"severity": "error",
"expression": "hasValue() or (children().count() > id.count())"
}, {
"key": "ext-1",
"human": "Must have either extensions or value[x], not both",
"xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
"source": "http://hl7.org/fhir/StructureDefinition/Extension",
"severity": "error",
"expression": "extension.exists() != value.exists()"
} ],
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.PraeventiveUntersuchungen.modifierExtension",
"requirements": "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](extensibility.html#modifierExtension).",
"min": 0,
"definition": "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).",
"isModifier": true,
"short": "Extensions that cannot be ignored even if unrecognized",
"mapping": [ {
"map": "N/A",
"identity": "rim"
} ],
"type": [ {
"code": "Extension"
} ],
"alias": [ "extensions", "user content", "modifiers" ],
"max": "*",
"id": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.PraeventiveUntersuchungen.modifierExtension",
"comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
"base": {
"max": "*",
"min": 0,
"path": "BackboneElement.modifierExtension"
},
"isModifierReason": "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them",
"isSummary": true
}, {
"constraint": [ {
"key": "ele-1",
"human": "All FHIR elements must have a @value or children",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element",
"severity": "error",
"expression": "hasValue() or (children().count() > id.count())"
} ],
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.PraeventiveUntersuchungen.Identifier",
"min": 0,
"definition": "interner Identifikator der präventiven Maßnahme",
"isModifier": false,
"short": "Identifier",
"type": [ {
"code": "string"
} ],
"max": "1",
"id": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.PraeventiveUntersuchungen.Identifier",
"comment": "Note that FHIR strings SHALL NOT exceed 1MB in size",
"base": {
"max": "1",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.PraeventiveUntersuchungen.Identifier"
},
"isSummary": false
}, {
"constraint": [ {
"key": "ele-1",
"human": "All FHIR elements must have a @value or children",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element",
"severity": "error",
"expression": "hasValue() or (children().count() > id.count())"
} ],
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.PraeventiveUntersuchungen.ArtUntersuchung",
"min": 0,
"definition": "Art der Untersuchung(z.B. Breast Imaging, MRI, MGR, US;Colonoscopy ; Esophago-gastro-duodenoscopy )",
"isModifier": false,
"short": "Art der Untersuchung",
"type": [ {
"code": "string"
} ],
"max": "1",
"id": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.PraeventiveUntersuchungen.ArtUntersuchung",
"comment": "Note that FHIR strings SHALL NOT exceed 1MB in size",
"base": {
"max": "1",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.PraeventiveUntersuchungen.ArtUntersuchung"
},
"isSummary": false
}, {
"constraint": [ {
"key": "ele-1",
"human": "All FHIR elements must have a @value or children",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element",
"severity": "error",
"expression": "hasValue() or (children().count() > id.count())"
} ],
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup",
"min": 0,
"definition": "Follow-up und Umsetzung der Therapieempfehlung",
"isModifier": false,
"short": "Follow-up und Umsetzung der Therapieempfehlung",
"mapping": [ {
"map": "n/a",
"identity": "rim"
} ],
"type": [ {
"code": "BackboneElement"
} ],
"extension": [ {
"url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status",
"valueCode": "normative"
}, {
"url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-normative-version",
"valueCode": "4.0.0"
} ],
"max": "*",
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup",
"condition": [ "ele-1" ],
"base": {
"max": "*",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup"
}
}, {
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.id",
"min": 0,
"definition": "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
"isModifier": false,
"short": "Unique id for inter-element referencing",
"mapping": [ {
"map": "n/a",
"identity": "rim"
} ],
"type": [ {
"code": "http://hl7.org/fhirpath/System.String",
"extension": [ {
"url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
"valueUrl": "string"
} ]
} ],
"representation": [ "xmlAttr" ],
"max": "1",
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.id",
"base": {
"max": "1",
"min": 0,
"path": "Element.id"
},
"isSummary": false
}, {
"constraint": [ {
"key": "ele-1",
"human": "All FHIR elements must have a @value or children",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element",
"severity": "error",
"expression": "hasValue() or (children().count() > id.count())"
}, {
"key": "ext-1",
"human": "Must have either extensions or value[x], not both",
"xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
"source": "http://hl7.org/fhir/StructureDefinition/Extension",
"severity": "error",
"expression": "extension.exists() != value.exists()"
} ],
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.extension",
"min": 0,
"definition": "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
"isModifier": false,
"short": "Additional content defined by implementations",
"mapping": [ {
"map": "n/a",
"identity": "rim"
} ],
"slicing": {
"rules": "open",
"description": "Extensions are always sliced by (at least) url",
"discriminator": [ {
"path": "url",
"type": "value"
} ]
},
"type": [ {
"code": "Extension"
} ],
"alias": [ "extensions", "user content" ],
"max": "*",
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.extension",
"comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
"base": {
"max": "*",
"min": 0,
"path": "Element.extension"
},
"isSummary": false
}, {
"constraint": [ {
"key": "ele-1",
"human": "All FHIR elements must have a @value or children",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element",
"severity": "error",
"expression": "hasValue() or (children().count() > id.count())"
}, {
"key": "ext-1",
"human": "Must have either extensions or value[x], not both",
"xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
"source": "http://hl7.org/fhir/StructureDefinition/Extension",
"severity": "error",
"expression": "extension.exists() != value.exists()"
} ],
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.modifierExtension",
"requirements": "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](extensibility.html#modifierExtension).",
"min": 0,
"definition": "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).",
"isModifier": true,
"short": "Extensions that cannot be ignored even if unrecognized",
"mapping": [ {
"map": "N/A",
"identity": "rim"
} ],
"type": [ {
"code": "Extension"
} ],
"alias": [ "extensions", "user content", "modifiers" ],
"max": "*",
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.modifierExtension",
"comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
"base": {
"max": "*",
"min": 0,
"path": "BackboneElement.modifierExtension"
},
"isModifierReason": "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them",
"isSummary": true
}, {
"constraint": [ {
"key": "ele-1",
"human": "All FHIR elements must have a @value or children",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element",
"severity": "error",
"expression": "hasValue() or (children().count() > id.count())"
} ],
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.Datum",
"min": 1,
"definition": "Datum des Follow-up",
"isModifier": false,
"short": "Datum",
"type": [ {
"code": "date"
} ],
"max": "1",
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.Datum",
"base": {
"max": "1",
"min": 1,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.Datum"
},
"isSummary": false
}, {
"constraint": [ {
"key": "ele-1",
"human": "All FHIR elements must have a @value or children",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element",
"severity": "error",
"expression": "hasValue() or (children().count() > id.count())"
} ],
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.MetachroneTumore",
"min": 0,
"definition": "Auftreten metachroner Tumore ja/nein",
"isModifier": false,
"short": "Auftreten Metachroner Tumore",
"type": [ {
"code": "code"
} ],
"max": "*",
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.MetachroneTumore",
"base": {
"max": "*",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.MetachroneTumore"
},
"isSummary": false
}, {
"constraint": [ {
"key": "ele-1",
"human": "All FHIR elements must have a @value or children",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element",
"severity": "error",
"expression": "hasValue() or (children().count() > id.count())"
} ],
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.MetachroneDiagnose",
"min": 1,
"definition": "Diagnose des metachronen Tumors laut ICD-10",
"isModifier": false,
"short": "Diagnose",
"type": [ {
"code": "code"
} ],
"max": "1",
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.MetachroneDiagnose",
"base": {
"max": "1",
"min": 1,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.MetachroneDiagnose"
},
"isSummary": false
}, {
"constraint": [ {
"key": "ele-1",
"human": "All FHIR elements must have a @value or children",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element",
"severity": "error",
"expression": "hasValue() or (children().count() > id.count())"
} ],
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.ECOG",
"min": 0,
"definition": "Eastern Cooperative Oncology Group (ECOG) Performance Status nach 0,1,2,3,4,5,unknown, not applicable",
"isModifier": false,
"short": "ECOG-Status",
"type": [ {
"code": "code"
} ],
"max": "1",
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.ECOG",
"base": {
"max": "1",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.ECOG"
},
"isSummary": false
}, {
"constraint": [ {
"key": "ele-1",
"human": "All FHIR elements must have a @value or children",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element",
"severity": "error",
"expression": "hasValue() or (children().count() > id.count())"
} ],
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.Vitalstatus",
"min": 1,
"definition": "Vitalstatus des Patienten zum Zeitpunkt des Follow-ups (lebend, verstorben, unbekannt)",
"isModifier": false,
"short": "Vitalstatus",
"type": [ {
"code": "code"
} ],
"max": "1",
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.Vitalstatus",
"base": {
"max": "1",
"min": 1,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.Vitalstatus"
},
"isSummary": false
}, {
"constraint": [ {
"key": "ele-1",
"human": "All FHIR elements must have a @value or children",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element",
"severity": "error",
"expression": "hasValue() or (children().count() > id.count())"
} ],
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.LetzterKontakt",
"min": 0,
"definition": "Datum des letzten Kontakts",
"isModifier": false,
"short": "Letzter Kontakt",
"type": [ {
"code": "date"
} ],
"max": "1",
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.LetzterKontakt",
"base": {
"max": "1",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.LetzterKontakt"
},
"isSummary": false
}, {
"constraint": [ {
"key": "ele-1",
"human": "All FHIR elements must have a @value or children",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element",
"severity": "error",
"expression": "hasValue() or (children().count() > id.count())"
} ],
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.Todesdatum",
"min": 0,
"definition": "Datum des Todes",
"isModifier": false,
"short": "Todesdatum",
"type": [ {
"code": "date"
} ],
"max": "1",
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.Todesdatum",
"base": {
"max": "1",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.Todesdatum"
},
"isSummary": false
}, {
"constraint": [ {
"key": "ele-1",
"human": "All FHIR elements must have a @value or children",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element",
"severity": "error",
"expression": "hasValue() or (children().count() > id.count())"
} ],
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.Therapien",
"min": 0,
"definition": "Therapien",
"isModifier": false,
"short": "Therapien",
"mapping": [ {
"map": "n/a",
"identity": "rim"
} ],
"type": [ {
"code": "BackboneElement"
} ],
"extension": [ {
"url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status",
"valueCode": "normative"
}, {
"url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-normative-version",
"valueCode": "4.0.0"
} ],
"max": "*",
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.Therapien",
"condition": [ "ele-1" ],
"base": {
"max": "*",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.Therapien"
}
}, {
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.Therapien.id",
"min": 0,
"definition": "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
"isModifier": false,
"short": "Unique id for inter-element referencing",
"mapping": [ {
"map": "n/a",
"identity": "rim"
} ],
"type": [ {
"code": "http://hl7.org/fhirpath/System.String",
"extension": [ {
"url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
"valueUrl": "string"
} ]
} ],
"representation": [ "xmlAttr" ],
"max": "1",
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.Therapien.id",
"base": {
"max": "1",
"min": 0,
"path": "Element.id"
},
"isSummary": false
}, {
"constraint": [ {
"key": "ele-1",
"human": "All FHIR elements must have a @value or children",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element",
"severity": "error",
"expression": "hasValue() or (children().count() > id.count())"
}, {
"key": "ext-1",
"human": "Must have either extensions or value[x], not both",
"xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
"source": "http://hl7.org/fhir/StructureDefinition/Extension",
"severity": "error",
"expression": "extension.exists() != value.exists()"
} ],
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.Therapien.extension",
"min": 0,
"definition": "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
"isModifier": false,
"short": "Additional content defined by implementations",
"mapping": [ {
"map": "n/a",
"identity": "rim"
} ],
"slicing": {
"rules": "open",
"description": "Extensions are always sliced by (at least) url",
"discriminator": [ {
"path": "url",
"type": "value"
} ]
},
"type": [ {
"code": "Extension"
} ],
"alias": [ "extensions", "user content" ],
"max": "*",
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.Therapien.extension",
"comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
"base": {
"max": "*",
"min": 0,
"path": "Element.extension"
},
"isSummary": false
}, {
"constraint": [ {
"key": "ele-1",
"human": "All FHIR elements must have a @value or children",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element",
"severity": "error",
"expression": "hasValue() or (children().count() > id.count())"
}, {
"key": "ext-1",
"human": "Must have either extensions or value[x], not both",
"xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
"source": "http://hl7.org/fhir/StructureDefinition/Extension",
"severity": "error",
"expression": "extension.exists() != value.exists()"
} ],
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.Therapien.modifierExtension",
"requirements": "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](extensibility.html#modifierExtension).",
"min": 0,
"definition": "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).",
"isModifier": true,
"short": "Extensions that cannot be ignored even if unrecognized",
"mapping": [ {
"map": "N/A",
"identity": "rim"
} ],
"type": [ {
"code": "Extension"
} ],
"alias": [ "extensions", "user content", "modifiers" ],
"max": "*",
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.Therapien.modifierExtension",
"comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
"base": {
"max": "*",
"min": 0,
"path": "BackboneElement.modifierExtension"
},
"isModifierReason": "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them",
"isSummary": true
}, {
"constraint": [ {
"key": "ele-1",
"human": "All FHIR elements must have a @value or children",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element",
"severity": "error",
"expression": "hasValue() or (children().count() > id.count())"
} ],
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.Therapien.reference",
"min": 1,
"definition": "Referenz auf Studien- / Therapieempfehlung",
"isModifier": false,
"short": "Referenz Studien-/ Therapieempfehlung",
"type": [ {
"code": "string"
} ],
"max": "1",
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.Therapien.reference",
"comment": "Note that FHIR strings SHALL NOT exceed 1MB in size",
"base": {
"max": "1",
"min": 1,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.Therapien.reference"
},
"isSummary": false
}, {
"constraint": [ {
"key": "ele-1",
"human": "All FHIR elements must have a @value or children",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element",
"severity": "error",
"expression": "hasValue() or (children().count() > id.count())"
} ],
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.Therapien.TherapieStart",
"min": 0,
"definition": "Startdatum der Therapie",
"isModifier": false,
"short": "Startdatum",
"type": [ {
"code": "date"
} ],
"max": "1",
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.Therapien.TherapieStart",
"base": {
"max": "1",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.Therapien.TherapieStart"
},
"isSummary": false
}, {
"constraint": [ {
"key": "ele-1",
"human": "All FHIR elements must have a @value or children",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element",
"severity": "error",
"expression": "hasValue() or (children().count() > id.count())"
} ],
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.Therapien.TherapieEnde",
"min": 0,
"definition": "Enddatum der Therapie",
"isModifier": false,
"short": "Enddatum",
"type": [ {
"code": "date"
} ],
"max": "1",
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.Therapien.TherapieEnde",
"base": {
"max": "1",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.Therapien.TherapieEnde"
},
"isSummary": false
}, {
"constraint": [ {
"key": "ele-1",
"human": "All FHIR elements must have a @value or children",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element",
"severity": "error",
"expression": "hasValue() or (children().count() > id.count())"
} ],
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.Therapien.TherapieWirkstoff",
"min": 0,
"definition": "Wirkstoff der Therapie nach ATC oder Text bei nicht-ATC-Wirkstoffen",
"isModifier": false,
"short": "Wirkstoff",
"type": [ {
"code": "code"
} ],
"max": "*",
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.Therapien.TherapieWirkstoff",
"base": {
"max": "*",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.Therapien.TherapieWirkstoff"
},
"isSummary": false
}, {
"constraint": [ {
"key": "ele-1",
"human": "All FHIR elements must have a @value or children",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element",
"severity": "error",
"expression": "hasValue() or (children().count() > id.count())"
} ],
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.Therapien.TherapieAnsprechen",
"min": 0,
"definition": "Therapieansprechen der Therapie (PD: Progression, SD:Stabile Erkrankung, PR:Partielle Remission, CR:Komplette Remission)",
"isModifier": false,
"short": "Ansprechen",
"type": [ {
"code": "code"
} ],
"max": "1",
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.Therapien.TherapieAnsprechen",
"base": {
"max": "1",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.Therapien.TherapieAnsprechen"
},
"isSummary": false
}, {
"constraint": [ {
"key": "ele-1",
"human": "All FHIR elements must have a @value or children",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element",
"severity": "error",
"expression": "hasValue() or (children().count() > id.count())"
} ],
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.Therapien.TherapieAnsprechenDatum",
"min": 0,
"definition": "Datum des Ansprechens der Vortherapie",
"isModifier": false,
"short": "Datum",
"type": [ {
"code": "date"
} ],
"max": "1",
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.Therapien.TherapieAnsprechenDatum",
"base": {
"max": "1",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.Therapien.TherapieAnsprechenDatum"
},
"isSummary": false
}, {
"constraint": [ {
"key": "ele-1",
"human": "All FHIR elements must have a @value or children",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element",
"severity": "error",
"expression": "hasValue() or (children().count() > id.count())"
} ],
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.Therapien.TherapieEndeGrund",
"min": 0,
"definition": "Grund für das Ende der Vortherapie",
"isModifier": false,
"short": "Ende der Therapie",
"type": [ {
"code": "code"
} ],
"max": "1",
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.Therapien.TherapieEndeGrund",
"base": {
"max": "1",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.Therapien.TherapieEndeGrund"
},
"isSummary": false
}, {
"constraint": [ {
"key": "ele-1",
"human": "All FHIR elements must have a @value or children",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element",
"severity": "error",
"expression": "hasValue() or (children().count() > id.count())"
} ],
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.Therapien.DatenquelleTherapieansprechen",
"min": 1,
"definition": "Datenquelle des Therapieansprechens (z.B. Arztbrief, Entlassungsbericht, Tumordokumentation)",
"isModifier": false,
"short": "Datenquelle Therapieansprechen",
"type": [ {
"code": "string"
} ],
"max": "1",
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.Therapien.DatenquelleTherapieansprechen",
"comment": "Note that FHIR strings SHALL NOT exceed 1MB in size",
"base": {
"max": "1",
"min": 1,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.Therapien.DatenquelleTherapieansprechen"
},
"isSummary": false
}, {
"constraint": [ {
"key": "ele-1",
"human": "All FHIR elements must have a @value or children",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element",
"severity": "error",
"expression": "hasValue() or (children().count() > id.count())"
} ],
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.PraeventiveMassnahmen",
"min": 0,
"definition": "Präventive Maßnahmen",
"isModifier": false,
"short": "Präventive Maßnahmen",
"mapping": [ {
"map": "n/a",
"identity": "rim"
} ],
"type": [ {
"code": "BackboneElement"
} ],
"extension": [ {
"url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status",
"valueCode": "normative"
}, {
"url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-normative-version",
"valueCode": "4.0.0"
} ],
"max": "*",
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.PraeventiveMassnahmen",
"condition": [ "ele-1" ],
"base": {
"max": "*",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.PraeventiveMassnahmen"
}
}, {
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.PraeventiveMassnahmen.id",
"min": 0,
"definition": "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
"isModifier": false,
"short": "Unique id for inter-element referencing",
"mapping": [ {
"map": "n/a",
"identity": "rim"
} ],
"type": [ {
"code": "http://hl7.org/fhirpath/System.String",
"extension": [ {
"url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
"valueUrl": "string"
} ]
} ],
"representation": [ "xmlAttr" ],
"max": "1",
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.PraeventiveMassnahmen.id",
"base": {
"max": "1",
"min": 0,
"path": "Element.id"
},
"isSummary": false
}, {
"constraint": [ {
"key": "ele-1",
"human": "All FHIR elements must have a @value or children",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element",
"severity": "error",
"expression": "hasValue() or (children().count() > id.count())"
}, {
"key": "ext-1",
"human": "Must have either extensions or value[x], not both",
"xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
"source": "http://hl7.org/fhir/StructureDefinition/Extension",
"severity": "error",
"expression": "extension.exists() != value.exists()"
} ],
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.PraeventiveMassnahmen.extension",
"min": 0,
"definition": "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
"isModifier": false,
"short": "Additional content defined by implementations",
"mapping": [ {
"map": "n/a",
"identity": "rim"
} ],
"slicing": {
"rules": "open",
"description": "Extensions are always sliced by (at least) url",
"discriminator": [ {
"path": "url",
"type": "value"
} ]
},
"type": [ {
"code": "Extension"
} ],
"alias": [ "extensions", "user content" ],
"max": "*",
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.PraeventiveMassnahmen.extension",
"comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
"base": {
"max": "*",
"min": 0,
"path": "Element.extension"
},
"isSummary": false
}, {
"constraint": [ {
"key": "ele-1",
"human": "All FHIR elements must have a @value or children",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element",
"severity": "error",
"expression": "hasValue() or (children().count() > id.count())"
}, {
"key": "ext-1",
"human": "Must have either extensions or value[x], not both",
"xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
"source": "http://hl7.org/fhir/StructureDefinition/Extension",
"severity": "error",
"expression": "extension.exists() != value.exists()"
} ],
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.PraeventiveMassnahmen.modifierExtension",
"requirements": "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored. This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](extensibility.html#modifierExtension).",
"min": 0,
"definition": "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).",
"isModifier": true,
"short": "Extensions that cannot be ignored even if unrecognized",
"mapping": [ {
"map": "N/A",
"identity": "rim"
} ],
"type": [ {
"code": "Extension"
} ],
"alias": [ "extensions", "user content", "modifiers" ],
"max": "*",
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.PraeventiveMassnahmen.modifierExtension",
"comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions. The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
"base": {
"max": "*",
"min": 0,
"path": "BackboneElement.modifierExtension"
},
"isModifierReason": "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them",
"isSummary": true
}, {
"constraint": [ {
"key": "ele-1",
"human": "All FHIR elements must have a @value or children",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element",
"severity": "error",
"expression": "hasValue() or (children().count() > id.count())"
} ],
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.PraeventiveMassnahmen.reference",
"min": 1,
"definition": "interne Referenz auf präventive Maßnahme",
"isModifier": false,
"short": "Referenz präventive Maßnahme",
"type": [ {
"code": "string"
} ],
"max": "1",
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.PraeventiveMassnahmen.reference",
"comment": "Note that FHIR strings SHALL NOT exceed 1MB in size",
"base": {
"max": "1",
"min": 1,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.PraeventiveMassnahmen.reference"
},
"isSummary": false
}, {
"constraint": [ {
"key": "ele-1",
"human": "All FHIR elements must have a @value or children",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element",
"severity": "error",
"expression": "hasValue() or (children().count() > id.count())"
} ],
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.PraeventiveMassnahmen.preventiveMeasureResult",
"min": 1,
"definition": "Ergebnis der präventiven Maßnahme (z.B. ohne Befund, benigner Befund, Malignom, unklar)",
"isModifier": false,
"short": "Ergebnis der präventiven Maßnahme",
"type": [ {
"code": "string"
} ],
"max": "1",
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.PraeventiveMassnahmen.preventiveMeasureResult",
"comment": "Note that FHIR strings SHALL NOT exceed 1MB in size",
"base": {
"max": "1",
"min": 1,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.PraeventiveMassnahmen.preventiveMeasureResult"
},
"isSummary": false
}, {
"constraint": [ {
"key": "ele-1",
"human": "All FHIR elements must have a @value or children",
"xpath": "@value|f:*|h:div",
"source": "http://hl7.org/fhir/StructureDefinition/Element",
"severity": "error",
"expression": "hasValue() or (children().count() > id.count())"
} ],
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.PraeventiveMassnahmen.preventiveMeasureDate",
"min": 0,
"definition": "Datum der präventiven Maßnahme",
"isModifier": false,
"short": "Datum der präventiven Maßnahme",
"type": [ {
"code": "date"
} ],
"max": "1",
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.PraeventiveMassnahmen.preventiveMeasureDate",
"base": {
"max": "1",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.PraeventiveMassnahmen.preventiveMeasureDate"
},
"isSummary": false
} ]
},
"status": "active",
"id": "6d9ab791-6fdf-41c8-bd99-37dcce5cee76",
"kind": "logical",
"url": "https://www.medizininformatik-initiative.de/fhir/ext/modul-onkologie/StructureDefinition/LogicalModel/mii-lm-mvgenomseq-onkologie",
"version": "2025.0.4",
"differential": {
"element": [ {
"id": "mii-lm-mvgenomseq-onkologie",
"path": "mii-lm-mvgenomseq-onkologie",
"short": "MII LM Modellvorhaben Genomsequenzierung Onkologie",
"definition": "MII LogicalModel Modellvorhaben Genomsequenzierung Onkologie"
}, {
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFall",
"max": "*",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall",
"type": [ {
"code": "BackboneElement"
} ],
"short": "Onkologie-Fall",
"definition": "Onkologie-Fall"
}, {
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Diagnose",
"max": "1",
"min": 1,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Diagnose",
"type": [ {
"code": "BackboneElement"
} ],
"short": "Diagnose",
"mapping": [ {
"map": "Condition",
"identity": "MVGenomSeq-Datenkranz-to-MII-FHIR"
} ],
"definition": "Diagnose"
}, {
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Diagnose.Haupttumordiagnose",
"max": "1",
"min": 1,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Diagnose.Haupttumordiagnose",
"type": [ {
"code": "code"
} ],
"short": "Haupttumordiagnose",
"mapping": [ {
"map": "Condition.code.coding.where(system='http://fhir.de/CodeSystem/bfarm/icd-10-gm').code",
"identity": "MVGenomSeq-Datenkranz-to-MII-FHIR"
} ],
"definition": "Haupttumordiagnose in ICD-10-GM"
}, {
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Diagnose.WeitereOnkologischeDiagnosen",
"max": "*",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Diagnose.WeitereOnkologischeDiagnosen",
"type": [ {
"code": "code"
} ],
"short": "Weitere onkologische Diagnosen",
"mapping": [ {
"map": "Condition.code.coding.where(system='http://fhir.de/CodeSystem/bfarm/icd-10-gm').code",
"identity": "MVGenomSeq-Datenkranz-to-MII-FHIR"
} ],
"definition": "Optional bei mehreren onkologischen Diagnosen, insbesondere Dokumentation als weiter onkologische Diagnose bei hereditären Tumordispositionssydroms (HT), bei HT zusätzliche Dokumentation ORPHAcode oder AlphaID, ein Code soweit vorhanden ist. Undiagnostizierte Erkrankungen sind mit ORPHA:616874 zu kodieren."
}, {
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Diagnose.Hauptdiagnosedatum",
"max": "1",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Diagnose.Hauptdiagnosedatum",
"type": [ {
"code": "date"
} ],
"short": "Hauptdiagnosedatum",
"mapping": [ {
"map": "Condition.extension.where(url='http://hl7.org/fhir/StructureDefinition/condition-assertedDate').valueDate",
"identity": "MVGenomSeq-Datenkranz-to-MII-FHIR"
} ],
"definition": "Datum der Erstdiagnose der Hauptdiagnose. Wenn Tag unbekannt -> 15. des Monats"
}, {
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Diagnose.ECOGStatus",
"max": "1",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Diagnose.ECOGStatus",
"type": [ {
"code": "code"
} ],
"short": "ECOG-Status",
"mapping": [ {
"map": "Observation.where(code='423740007' and system='http://snomed.info/sct').valueCodeableConcept.coding.code",
"identity": "MVGenomSeq-Datenkranz-to-MII-FHIR"
} ],
"definition": "Eastern Cooperative Oncology Group (ECOG) Performance Status nach 0,1,2,3,4,5,unknown, not applicable"
}, {
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Diagnose.KeimbahndiagnoseVorhanden",
"max": "1",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Diagnose.KeimbahndiagnoseVorhanden",
"type": [ {
"code": "code"
} ],
"short": "Keimbahndiagnose vorhanden",
"mapping": [ {
"map": "no direct match, vsl. über FHIRPath automatisch generieren, wenn Keimbahndiagnose.exists()",
"identity": "MVGenomSeq-Datenkranz-to-MII-FHIR"
} ],
"definition": "Ja, Nein, unbekannt"
}, {
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Diagnose.Keimbahndiagnose",
"max": "*",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Diagnose.Keimbahndiagnose",
"type": [ {
"code": "code"
} ],
"short": "Keimbahndiagnose",
"mapping": [ {
"map": "no direct match. Keimbahndiagnose existiert als Konzept nicht, hier könnte / müsste mit Condition.category gearbeitet werden, z.B. SNOMED Hereditary cancer-predisposing syndrome (disorder)",
"identity": "MVGenomSeq-Datenkranz-to-MII-FHIR"
} ],
"definition": "Keimbahndiagnosen nach ICD-10-GM.Bei Diagnose eines hereditären Tumordispositionssydroms als Teil der OE ist verpflichtend anzugeben mit ICD10 und ORPHA oder AlphaID"
}, {
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Diagnose.HPOPhaenotypisierung",
"max": "*",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Diagnose.HPOPhaenotypisierung",
"type": [ {
"code": "code"
} ],
"short": "Phänotypisierung nach HPO",
"mapping": [ {
"map": "Observation.where(valueCodeableConcept.coding.system='http://human-phenotype-ontology.org')",
"identity": "MVGenomSeq-Datenkranz-to-MII-FHIR"
} ],
"definition": "Human Phenotype Ontology.Bei Diagnose eines hereditären Tumordispositionssydroms als Teil der OE, wenn vorhanden angeben (optional)"
}, {
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Diagnose.Histologie",
"max": "1",
"min": 1,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Diagnose.Histologie",
"type": [ {
"code": "code"
} ],
"short": "Histologie nach ICD-O-3",
"mapping": [ {
"map": "Condition.extension.where(url='https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-ex-onko-histology-morphology-behavior-icdo3').valueCodeableConcept.coding.code",
"identity": "MVGenomSeq-Datenkranz-to-MII-FHIR"
} ],
"definition": "Histologische Morphologie und Verhalten nach ICD-O-3"
}, {
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Diagnose.Topographie",
"max": "1",
"min": 1,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Diagnose.Topographie",
"type": [ {
"code": "code"
} ],
"short": "Topographie nach ICD-O-3",
"mapping": [ {
"map": "Condition.bodySite.coding.code",
"identity": "MVGenomSeq-Datenkranz-to-MII-FHIR"
} ],
"definition": "Topographie des Tumors nach ICD-O-3"
}, {
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Diagnose.Grading",
"max": "1",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Diagnose.Grading",
"type": [ {
"code": "code"
} ],
"short": "Differenzierungsgrad",
"mapping": [ {
"map": "Observation.where(code.coding.code='33732-9' and code.coding.system='http://loinc.org').valueCodeableConcept.coding.code",
"identity": "MVGenomSeq-Datenkranz-to-MII-FHIR"
} ],
"definition": "Gibt den Differenzierungsgrad des Tumors entsprechend der aktuellen TNM-Auflage an, Bei der Klassifikation sind die einschlägigen Regeln der Literatur (TNM) zu beachten."
}, {
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Diagnose.TNMSchluessel",
"max": "1",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Diagnose.TNMSchluessel",
"type": [ {
"code": "string"
} ],
"short": "TNM-Klassifikation",
"mapping": [ {
"map": "Observation.where(code.coding.code='33732-9' and code.coding.system='http://snomed.info/sct').valueCodeableConcept.coding.code",
"identity": "MVGenomSeq-Datenkranz-to-MII-FHIR"
} ],
"definition": "TNM-Klassifikation des Tumors"
}, {
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Diagnose.TNMSystematik",
"max": "1",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Diagnose.TNMSystematik",
"type": [ {
"code": "code"
} ],
"short": "TNM-Systematik",
"mapping": [ {
"map": "Laut Krebsregisterdaten nur UICC vorgesehen? kein expiziter Datenpunkt außer Version",
"identity": "MVGenomSeq-Datenkranz-to-MII-FHIR"
} ],
"definition": "TNM-Systematik nach AJCC oder UICC"
}, {
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Diagnose.WeitereKlassifikationen",
"max": "*",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Diagnose.WeitereKlassifikationen",
"type": [ {
"code": "string"
} ],
"short": "Weitere Klassifikationen",
"mapping": [ {
"map": "no direkt match - Observation - Nutzung des Profils WeitereKlassifikationen, aber aufgrund der Vielfalt der Klassifikationen keine direkte Zuordnung möglich",
"identity": "MVGenomSeq-Datenkranz-to-MII-FHIR"
} ],
"definition": "Weitere Klassifikationen des Tumors zum Diagnosezeitpunkt"
}, {
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Diagnose.DiagnostischeVoruntersuchungen",
"max": "*",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Diagnose.DiagnostischeVoruntersuchungen",
"type": [ {
"code": "code"
} ],
"short": "Diagnostische Voruntersuchungen",
"mapping": [ {
"map": "no direkt match",
"identity": "MVGenomSeq-Datenkranz-to-MII-FHIR"
} ],
"definition": "Diagnostische Voruntersuchungen zum Diagnosezeitpunkt. Bewertung der durchgeführten genetischen Diagnostik, nur für heriditäre Prädispositionssyndrome/ Erbliche Tumore"
}, {
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Vordiagnostik",
"max": "*",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Vordiagnostik",
"type": [ {
"code": "BackboneElement"
} ],
"short": "Vordiagnostik",
"mapping": [ {
"map": "Vordiagnostik",
"identity": "MVGenomSeq-Datenkranz-to-MII-FHIR"
} ],
"definition": "Vordiagnostik"
}, {
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Vordiagnostik.ArtDiagnostik",
"max": "1",
"min": 1,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Vordiagnostik.ArtDiagnostik",
"type": [ {
"code": "code"
} ],
"short": "Diagnostik",
"mapping": [ {
"map": "Diagnoste)",
"identity": "MVGenomSeq-Datenkranz-to-MII-FHIR"
} ],
"definition": "Diagnostik, die vor dem MV Genomseq, durchgeführt wurde (Vorbefunde)"
}, {
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Vordiagnostik.DatumDiagnostik",
"max": "1",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.Vordiagnostik.DatumDiagnostik",
"type": [ {
"code": "date"
} ],
"short": "Datum",
"mapping": [ {
"map": "Datum Diagnostik",
"identity": "MVGenomSeq-Datenkranz-to-MII-FHIR"
} ],
"definition": "Datum der Diagnostik"
}, {
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFall.MolekulareVorbefunde",
"max": "*",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.MolekulareVorbefunde",
"type": [ {
"code": "BackboneElement"
} ],
"short": "klinisch relevante Ergebnisse der Diagnostik",
"mapping": [ {
"map": "klinisch relevante Ergebnisse der Diagnostik",
"identity": "MVGenomSeq-Datenkranz-to-MII-FHIR"
} ],
"definition": "klinisch relevante Ergebnisse der Diagnostik"
}, {
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFall.MolekulareVorbefunde.Gen",
"max": "1",
"min": 1,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.MolekulareVorbefunde.Gen",
"type": [ {
"code": "code"
} ],
"short": "Gen",
"mapping": [ {
"map": "Genert nach HGNC",
"identity": "MVGenomSeq-Datenkranz-to-MII-FHIR"
} ],
"definition": "Gen kodiert nach HGNC"
}, {
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFall.MolekulareVorbefunde.Transkript",
"max": "1",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.MolekulareVorbefunde.Transkript",
"type": [ {
"code": "code"
} ],
"short": "Transkript",
"mapping": [ {
"map": "Transkriranskript kodiert nach Ensembl/RefSeq",
"identity": "MVGenomSeq-Datenkranz-to-MII-FHIR"
} ],
"definition": "Transkript kodiert nach Ensembl/RefSeq"
}, {
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFall.MolekulareVorbefunde.DNAChange",
"max": "1",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.MolekulareVorbefunde.DNAChange",
"type": [ {
"code": "code"
} ],
"short": "DNA-Veränderung",
"mapping": [ {
"map": "DNA-VeränVerändung nach cHGVS",
"identity": "MVGenomSeq-Datenkranz-to-MII-FHIR"
} ],
"definition": "DNA-Verändung nach cHGVS"
}, {
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFall.MolekulareVorbefunde.ProteinChange",
"max": "1",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.MolekulareVorbefunde.ProteinChange",
"type": [ {
"code": "code"
} ],
"short": "Protein-Veränderung",
"mapping": [ {
"map": "Protein-Verändotein-Veränderung nach pHGVS",
"identity": "MVGenomSeq-Datenkranz-to-MII-FHIR"
} ],
"definition": "Protein-Veränderung nach pHGVS"
}, {
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFall.MolekulareVorbefunde.TypAlteration",
"max": "1",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.MolekulareVorbefunde.TypAlteration",
"type": [ {
"code": "code"
} ],
"short": "Typ der Alteration",
"mapping": [ {
"map": "Typ der Alteratr Alteration / Variantenklasse nach Sequence ontology (SO)",
"identity": "MVGenomSeq-Datenkranz-to-MII-FHIR"
} ],
"definition": "Typ der Alteration / Variantenklasse nach Sequence ontology (SO)"
}, {
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFall.MolekulareVorbefunde.KomplexeAlteration",
"max": "1",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.MolekulareVorbefunde.KomplexeAlteration",
"type": [ {
"code": "string"
} ],
"short": "Komplexe Alteration",
"mapping": [ {
"map": "Komplexe AlteratAusführliche Beschreibung",
"identity": "MVGenomSeq-Datenkranz-to-MII-FHIR"
} ],
"definition": "Ausführliche Beschreibung bei komplexen Alteration z.B. Fusion"
}, {
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFall.SystemischeVortherapien",
"max": "*",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.SystemischeVortherapien",
"type": [ {
"code": "BackboneElement"
} ],
"short": "Systemische Vortherapien",
"mapping": [ {
"map": "Procedure",
"identity": "MVGenomSeq-Datenkranz-to-MII-FHIR"
} ],
"definition": "Systemische Vortherapien"
}, {
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFall.SystemischeVortherapien.ArtTherapie",
"max": "1",
"min": 1,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.SystemischeVortherapien.ArtTherapie",
"type": [ {
"code": "code"
} ],
"short": "Bezug zur operativen Therapie",
"mapping": [ {
"map": "Procedure.extension.where(url='StellungZurOp')",
"identity": "MVGenomSeq-Datenkranz-to-MII-FHIR"
} ],
"definition": "Bezug der Vortherapie zu einer operativen Therapie, z.B. adjuvant, neoadjuvant"
}, {
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFall.SystemischeVortherapien.IntentionTherapie",
"max": "1",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.SystemischeVortherapien.IntentionTherapie",
"type": [ {
"code": "code"
} ],
"short": "Intention",
"mapping": [ {
"map": "Procedure.extension.where(url='Intention')",
"identity": "MVGenomSeq-Datenkranz-to-MII-FHIR"
} ],
"definition": "Intention der Vortherapie, z.B. kurativ, palliativ"
}, {
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFall.SystemischeVortherapien.Substanz",
"max": "*",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.SystemischeVortherapien.Substanz",
"type": [ {
"code": "code"
} ],
"short": "Substanz",
"mapping": [ {
"map": "MedicationStatement.medicationCode.coding[atc-de].code",
"identity": "MVGenomSeq-Datenkranz-to-MII-FHIR"
} ],
"definition": "Substanz der Vortherapie nach ATC oder Text bei nicht-ATC-Wirkstoffen"
}, {
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFall.SystemischeVortherapien.Therapiestart",
"max": "1",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.SystemischeVortherapien.Therapiestart",
"type": [ {
"code": "date"
} ],
"short": "Startdatum",
"mapping": [ {
"map": "Procedure.effectivePeriod.start",
"identity": "MVGenomSeq-Datenkranz-to-MII-FHIR"
} ],
"definition": "Startdatum der Vortherapie. Wenn Datum unbekannt, dann 15. des Monats"
}, {
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFall.SystemischeVortherapien.Therapieende",
"max": "1",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.SystemischeVortherapien.Therapieende",
"type": [ {
"code": "date"
} ],
"short": "Enddatum",
"mapping": [ {
"map": "Procedure.effectivePeriod.end",
"identity": "MVGenomSeq-Datenkranz-to-MII-FHIR"
} ],
"definition": "Enddatum der Vortherapie. Wenn Datum unbekannt, dann 15. des Monats"
}, {
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFall.SystemischeVortherapien.EndeGrund",
"max": "1",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.SystemischeVortherapien.EndeGrund",
"type": [ {
"code": "code"
} ],
"short": "Ende der Therapie",
"mapping": [ {
"map": "Procedure.outcome",
"identity": "MVGenomSeq-Datenkranz-to-MII-FHIR"
} ],
"definition": "Grund für das Ende der Vortherapie"
}, {
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFall.SystemischeVortherapien.TherapieAnsprechen",
"max": "1",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.SystemischeVortherapien.TherapieAnsprechen",
"type": [ {
"code": "code"
} ],
"short": "Ansprechen",
"mapping": [ {
"map": "Verlauf.valueCodeableConcept.coding.code",
"identity": "MVGenomSeq-Datenkranz-to-MII-FHIR"
} ],
"definition": "Therapieansprechen der fallrelevante, systemische Vortherapie (PD: Progression, SD:Stabile Erkrankung, PR:Partielle Remission, CR:Komplette Remission)"
}, {
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFall.SystemischeVortherapien.TherapieAnsprechenDatum",
"max": "1",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFall.SystemischeVortherapien.TherapieAnsprechenDatum",
"type": [ {
"code": "date"
} ],
"short": "Datum",
"mapping": [ {
"map": "Verlauf.effectiveDateTime",
"identity": "MVGenomSeq-Datenkranz-to-MII-FHIR"
} ],
"definition": "Datum des Ansprechens der Vortherapie"
}, {
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular",
"max": "*",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular",
"type": [ {
"code": "BackboneElement"
} ],
"short": "Molekulare Diagnostik",
"definition": "Molekulare Diagnostik"
}, {
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.EinfacheVariante",
"max": "*",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.EinfacheVariante",
"type": [ {
"code": "BackboneElement"
} ],
"short": "Einfache Variante inkl. Fusionen im codierenden Bereich",
"definition": "Einfache Variante inkl. Fusionen im codierenden Bereich"
}, {
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.EinfacheVariante.Identifier",
"max": "1",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.EinfacheVariante.Identifier",
"type": [ {
"code": "string"
} ],
"short": "Identifier",
"definition": "interner Identifikator der Variante"
}, {
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.EinfacheVariante.Gen",
"max": "1",
"min": 1,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.EinfacheVariante.Gen",
"type": [ {
"code": "code"
} ],
"short": "Gen",
"definition": "Gen kodiert nach HGNC"
}, {
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.EinfacheVariante.Transkript",
"max": "1",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.EinfacheVariante.Transkript",
"type": [ {
"code": "code"
} ],
"short": "Transkript",
"definition": "Transkript kodiert nach Ensembl/RefSeq"
}, {
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.EinfacheVariante.DNAChange",
"max": "1",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.EinfacheVariante.DNAChange",
"type": [ {
"code": "code"
} ],
"short": "DNA-Veränderung",
"definition": "DNA-Verändung nach cHGVS"
}, {
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.EinfacheVariante.ProteinChange",
"max": "1",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.EinfacheVariante.ProteinChange",
"type": [ {
"code": "code"
} ],
"short": "Protein-Veränderung",
"definition": "Protein-Veränderung nach pHGVS"
}, {
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.EinfacheVariante.TypAlteration",
"max": "1",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.EinfacheVariante.TypAlteration",
"type": [ {
"code": "code"
} ],
"short": "Typ der Alteration",
"definition": "Typ der Alteration / Variantenklasse nach Sequence ontology (SO)"
}, {
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.EinfacheVariante.Lokalization",
"max": "1",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.EinfacheVariante.Lokalization",
"type": [ {
"code": "code"
} ],
"short": "Lokalisation der Variante",
"definition": "Lokalisation im kodierenden, regulatorischen oder intergenischen Bereich"
}, {
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.EinfacheVariante.LossOfHeterozygosity",
"max": "1",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.EinfacheVariante.LossOfHeterozygosity",
"type": [ {
"code": "code"
} ],
"short": "Loss of Heterozygosity (LOH)",
"definition": "Loss of Heterozygosity (LOH) im Bereich der Variante Ja / Nein"
}, {
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.CopyNumberVariante",
"max": "*",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.CopyNumberVariante",
"type": [ {
"code": "BackboneElement"
} ],
"short": "Variante mit Kopienzahlveränderung (Copy Number Variation, CNV)",
"definition": "Variante mit Kopienzahlveränderung (Copy Number Variation, CNV)"
}, {
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.CopyNumberVariante.Identifier",
"max": "1",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.CopyNumberVariante.Identifier",
"type": [ {
"code": "string"
} ],
"short": "Identifier",
"definition": "interner Identifikator der Variante"
}, {
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.CopyNumberVariante.CNVTyp",
"max": "*",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.CopyNumberVariante.CNVTyp",
"type": [ {
"code": "BackboneElement"
} ],
"short": "CNV-Typ",
"definition": "Komplettverlust, partieller Verlust, Amplifikation"
}, {
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.CopyNumberVariante.Quellprobe",
"max": "1",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.CopyNumberVariante.Quellprobe",
"type": [ {
"code": "code"
} ],
"short": "Art der Quellprobe",
"definition": "Art der Quellprobe (somatisch oder Keimbahn)"
}, {
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.CopyNumberVariante.Gen",
"max": "1",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.CopyNumberVariante.Gen",
"type": [ {
"code": "code"
} ],
"short": "Gen",
"definition": "Gen kodiert nach HGNC - falls nur ein Gen betreffend"
}, {
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.CopyNumberVariante.Chromosom",
"max": "1",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.CopyNumberVariante.Chromosom",
"type": [ {
"code": "code"
} ],
"short": "Chromosom",
"definition": "Chromosom"
}, {
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.CopyNumberVariante.CNVStartPosition",
"max": "1",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.CopyNumberVariante.CNVStartPosition",
"type": [ {
"code": "integer"
} ],
"short": "CNV-Start",
"definition": "Startposition des CNV basierend auf Hg38"
}, {
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.CopyNumberVariante.CNVEndPosition",
"max": "1",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.CopyNumberVariante.CNVEndPosition",
"type": [ {
"code": "integer"
} ],
"short": "CNV-Ende",
"definition": "Endposition des CNV basierend auf Hg38"
}, {
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.CopyNumberVariante.CopyNumber",
"max": "1",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.CopyNumberVariante.CopyNumber",
"type": [ {
"code": "integer"
} ],
"short": "Copy Number",
"definition": "Copy Number"
}, {
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.CopyNumberVariante.Lokalization",
"max": "1",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.CopyNumberVariante.Lokalization",
"type": [ {
"code": "code"
} ],
"short": "Lokalisation der Variante",
"definition": "Lokalisation im kodierenden, regulatorischen oder intergenischen Bereich"
}, {
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.StrukturelleVariante",
"max": "*",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.StrukturelleVariante",
"type": [ {
"code": "BackboneElement"
} ],
"short": "Strukturelle Variante",
"definition": "Strukturelle Variante"
}, {
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.StrukturelleVariante.Identifier",
"max": "1",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.StrukturelleVariante.Identifier",
"type": [ {
"code": "string"
} ],
"short": "Identifier",
"definition": "interner Identifikator der Variante"
}, {
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.StrukturelleVariante.Quellprobe",
"max": "1",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.StrukturelleVariante.Quellprobe",
"type": [ {
"code": "code"
} ],
"short": "Art der Quellprobe",
"definition": "Art der Quellprobe (somatisch oder Keimbahn)"
}, {
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.StrukturelleVariante.Gen",
"max": "1",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.StrukturelleVariante.Gen",
"type": [ {
"code": "code"
} ],
"short": "Gen",
"definition": "N-terminales Gen"
}, {
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.StrukturelleVariante.GenC",
"max": "1",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.StrukturelleVariante.GenC",
"type": [ {
"code": "code"
} ],
"short": "Gen",
"definition": "C-terminales Gen, falls in-frame und kodierend"
}, {
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.StrukturelleVariante.StrukturTyp",
"max": "1",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.StrukturelleVariante.StrukturTyp",
"type": [ {
"code": "code"
} ],
"short": "Variantentyp",
"definition": "Variantentyp (Inversion, Translokation, Deletion, Insertion, Duplikation)"
}, {
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.StrukturelleVariante.Beschreibung",
"max": "1",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.StrukturelleVariante.Beschreibung",
"type": [ {
"code": "code"
} ],
"short": "Beschreibung der Variante",
"definition": "Beschreibung der Variante nach HGVS oder ISCN"
}, {
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.StrukturelleVariante.Nachweismethode",
"max": "1",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.StrukturelleVariante.Nachweismethode",
"type": [ {
"code": "code"
} ],
"short": "Nachweismethode",
"definition": "Nachweismethode (DNA / RNA)"
}, {
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.StrukturelleVariante.Lokalization",
"max": "1",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.StrukturelleVariante.Lokalization",
"type": [ {
"code": "code"
} ],
"short": "Lokalisation der Variante",
"definition": "Lokalisation im kodierenden, regulatorischen oder intergenischen Bereich"
}, {
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.ExpressionsVariante",
"max": "*",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.ExpressionsVariante",
"type": [ {
"code": "BackboneElement"
} ],
"short": "Expressionsvariante",
"definition": "Expressionsvariante"
}, {
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.ExpressionsVariante.Identifier",
"max": "1",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.ExpressionsVariante.Identifier",
"type": [ {
"code": "string"
} ],
"short": "Identifier",
"definition": "interner Identifikator der Variante"
}, {
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.ExpressionsVariante.Gen",
"max": "1",
"min": 1,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.ExpressionsVariante.Gen",
"type": [ {
"code": "code"
} ],
"short": "Gen",
"definition": "Gen kodiert nach HGNC"
}, {
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.ExpressionsVariante.Expression",
"max": "1",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.ExpressionsVariante.Expression",
"type": [ {
"code": "code"
} ],
"short": "Expression",
"definition": "Expression des Gens (über- oder unterexprimiert)"
}, {
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.ExpressionsVariante.Bewertungsgrundlage",
"max": "1",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.ExpressionsVariante.Bewertungsgrundlage",
"type": [ {
"code": "string"
} ],
"short": "Bewertungsgrundlage",
"definition": "Bewertungsgrundlage der Expression (z.B. Vergleichskohorte von 400 Patienten)"
}, {
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.ExpressionsVariante.TMB",
"max": "1",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.ExpressionsVariante.TMB",
"type": [ {
"code": "decimal"
} ],
"short": "Tumor Mutational Burden (TMB)",
"definition": "Tumor Mutational Burden (TMB) in Mut/Mb"
}, {
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.ExpressionsVariante.HRD",
"max": "1",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.ExpressionsVariante.HRD",
"type": [ {
"code": "code"
} ],
"short": "Homologous Recombination Deficiency (HRD)",
"definition": "Homologous Recombination Deficiency (HRD) erhöht ja/nein"
}, {
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.ExpressionsVariante.LST",
"max": "1",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.ExpressionsVariante.LST",
"type": [ {
"code": "code"
} ],
"short": "Large Scale Transition (LST)",
"definition": "Large Scale Transition (LST) erhöht ja/nein"
}, {
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.ExpressionsVariante.TAI",
"max": "1",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.ExpressionsVariante.TAI",
"type": [ {
"code": "code"
} ],
"short": "Telomeric Allelic Imbalance (TAI)",
"definition": "Telomeric Allelic Imbalance (TAI) erhöht ja/nein"
}, {
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.ExpressionsVariante.SBS",
"max": "1",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.ExpressionsVariante.SBS",
"type": [ {
"code": "code"
} ],
"short": "Single Base Substitution (SBS)",
"definition": "Single Base Substitution (SBS) erhöht ja/nein"
}, {
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.ExpressionsVariante.SBSSignature",
"max": "1",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.ExpressionsVariante.SBSSignature",
"type": [ {
"code": "code"
} ],
"short": "Single Base Substitution Signature",
"definition": "Single Base Substitution Signature"
}, {
"id": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.ExpressionsVariante.Lokalization",
"max": "1",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieMolekular.ExpressionsVariante.Lokalization",
"type": [ {
"code": "code"
} ],
"short": "Lokalisation der Variante",
"definition": "Lokalisation im kodierenden, regulatorischen oder intergenischen Bereich"
}, {
"id": "mii-lm-mvgenomseq-onkologie.OnkologiePlan",
"max": "*",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan",
"type": [ {
"code": "BackboneElement"
} ],
"short": "Therapieplan",
"definition": "Therapieplan"
}, {
"id": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.MolekularesTumorboard",
"max": "*",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.MolekularesTumorboard",
"type": [ {
"code": "BackboneElement"
} ],
"short": "Molekulares Tumorboard",
"definition": "Molekulares Tumorboard"
}, {
"id": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.MolekularesTumorboard.Datum",
"max": "1",
"min": 1,
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.MolekularesTumorboard.Datum",
"type": [ {
"code": "date"
} ],
"short": "Datum",
"definition": "Datum des Tumorboards"
}, {
"id": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.MolekularesTumorboard.EmpfehlungStudie",
"max": "1",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.MolekularesTumorboard.EmpfehlungStudie",
"type": [ {
"code": "code"
} ],
"short": "Empfehlung Studie",
"definition": "Empfehlung zur Studienteilnahme ja/nein"
}, {
"id": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.MolekularesTumorboard.EmpfehlungBeratung",
"max": "1",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.MolekularesTumorboard.EmpfehlungBeratung",
"type": [ {
"code": "code"
} ],
"short": "Empfehlung humangenetische Beratung",
"definition": "Empfehlung zu einer humangenetischen Beratung ja/nein"
}, {
"id": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.MolekularesTumorboard.EmpfehlungReevaluation",
"max": "1",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.MolekularesTumorboard.EmpfehlungReevaluation",
"type": [ {
"code": "code"
} ],
"short": "Empfehlung Reevaluation",
"definition": "Empfehlung zur Reevaluation der molekularen Diagnostik ja/nein"
}, {
"id": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.MolekularesTumorboard.EmpfehlungOperation",
"max": "1",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.MolekularesTumorboard.EmpfehlungOperation",
"type": [ {
"code": "code"
} ],
"short": "Empfehlung Operation",
"definition": "Empfehlung zur Operation ja/nein"
}, {
"id": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.MolekularesTumorboard.EmpfehlungOperationArt",
"max": "1",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.MolekularesTumorboard.EmpfehlungOperationArt",
"type": [ {
"code": "code"
} ],
"short": "empfohlenene Operation",
"definition": "empfohlenen Operation"
}, {
"id": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.MolekularesTumorboard.EmpfehlungOperationRisikoreduzierend",
"max": "1",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.MolekularesTumorboard.EmpfehlungOperationRisikoreduzierend",
"type": [ {
"code": "code"
} ],
"short": "empfohlene Operation ist riskoreduzierend",
"definition": "empfohlenen Operation ist riskoreduzierend ja/nein"
}, {
"id": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.MolekularesTumorboard.EmpfehlungOperationTherapeutisch",
"max": "1",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.MolekularesTumorboard.EmpfehlungOperationTherapeutisch",
"type": [ {
"code": "code"
} ],
"short": "empfohlene Operation ist therapeutisch",
"definition": "empfohlenene Operation ist therapeutisch ja/nein"
}, {
"id": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.MolekularesTumorboard.DurchgefuehrteOperation",
"max": "*",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.MolekularesTumorboard.DurchgefuehrteOperation",
"type": [ {
"code": "code"
} ],
"short": "Durchgeführte Operation",
"definition": "Durchgeführte Operation nach OPS inkl. Version"
}, {
"id": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.EmpfohleneStudie",
"max": "*",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.EmpfohleneStudie",
"type": [ {
"code": "BackboneElement"
} ],
"short": "Empfohlene Studieneinschlüsse",
"definition": "Empfohlene Studieneinschlüsse"
}, {
"id": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.EmpfohleneStudie.Identifier",
"max": "1",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.EmpfohleneStudie.Identifier",
"type": [ {
"code": "string"
} ],
"short": "Identifier",
"definition": "interner Identifikator der Studie"
}, {
"id": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.EmpfohleneStudie.Register",
"max": "1",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.EmpfohleneStudie.Register",
"type": [ {
"code": "code"
} ],
"short": "Register",
"definition": "Registersystematik, in dem die StudienID angegeben wird (NCT, EudraCT/CTIS, DRKS, andere, unbekannt)"
}, {
"id": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.EmpfohleneStudie.StudienID",
"max": "1",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.EmpfohleneStudie.StudienID",
"type": [ {
"code": "code"
} ],
"short": "Studie",
"definition": "StudienID in einer Registersystematik"
}, {
"id": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.EmpfohleneStudie.Studienname",
"max": "1",
"min": 1,
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.EmpfohleneStudie.Studienname",
"type": [ {
"code": "string"
} ],
"short": "Name der Studie",
"definition": "Name der Studie"
}, {
"id": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.EmpfohleneStudie.Substanzen",
"max": "*",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.EmpfohleneStudie.Substanzen",
"type": [ {
"code": "code"
} ],
"short": "Substanzen",
"definition": "Substanzen, die in der Studie eingesetzt werden, nach ATC kodiert"
}, {
"id": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.EmpfohleneStudie.Evidenzgrad",
"max": "1",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.EmpfohleneStudie.Evidenzgrad",
"type": [ {
"code": "code"
} ],
"short": "Evidenzgrad",
"definition": "Evidenzgrad"
}, {
"id": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.EmpfohleneStudie.ZusatzverweiseEvidenzgraduierung",
"max": "*",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.EmpfohleneStudie.ZusatzverweiseEvidenzgraduierung",
"type": [ {
"code": "string"
} ],
"short": "Zusatzverweise zur Evidenzgraduierung",
"definition": "Zusatzverweise zur Evidenzgraduierung"
}, {
"id": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.EmpfohleneStudie.Prioritaet",
"max": "1",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.EmpfohleneStudie.Prioritaet",
"type": [ {
"code": "code"
} ],
"short": "Priorität",
"definition": "Priorität der Studie, falls mehrere Studien empfohlen wurde. 1 ist höchste Priorität"
}, {
"id": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.EmpfohleneStudie.Variante",
"max": "*",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.EmpfohleneStudie.Variante",
"type": [ {
"code": "code"
} ],
"short": "Variante",
"definition": "interne VariantenID der Variante, die für die Studie relevant ist"
}, {
"id": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.Therapieempfehlung",
"max": "*",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.Therapieempfehlung",
"type": [ {
"code": "BackboneElement"
} ],
"short": "String",
"definition": "String"
}, {
"id": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.Therapieempfehlung.Identifier",
"max": "1",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.Therapieempfehlung.Identifier",
"type": [ {
"code": "string"
} ],
"short": "Identifier",
"definition": "interner Identifikator der Therapieempfehlung"
}, {
"id": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.Therapieempfehlung.EmpfehlungTyp",
"max": "1",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.Therapieempfehlung.EmpfehlungTyp",
"type": [ {
"code": "code"
} ],
"short": "Typ der Empfehlung",
"definition": "Typ der Empfehlung (z.B. inlabel, offlabel, compassionate use, unknown, secondary preventive)"
}, {
"id": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.Therapieempfehlung.Substanz",
"max": "*",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.Therapieempfehlung.Substanz",
"type": [ {
"code": "code"
} ],
"short": "Substanzen",
"definition": "Substanzen, die empfohlen werden, nach ATC kodiert"
}, {
"id": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.Therapieempfehlung.Evidenzgrad",
"max": "1",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.Therapieempfehlung.Evidenzgrad",
"type": [ {
"code": "code"
} ],
"short": "Evidenzgrad",
"definition": "Evidenzgrad (m1A - m4, unbekannt)"
}, {
"id": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.Therapieempfehlung.Prioritaet",
"max": "1",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.Therapieempfehlung.Prioritaet",
"type": [ {
"code": "code"
} ],
"short": "Priorität",
"definition": "Priorität der Therapieempfehlung, falls mehrere Empfehlungen gegeben wurden. 1 ist höchste Priorität"
}, {
"id": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.Therapieempfehlung.Variante",
"max": "*",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.Therapieempfehlung.Variante",
"type": [ {
"code": "code"
} ],
"short": "Variante",
"definition": "interne VariantenID der Variante, die für die Therapieempfehlung relevant ist"
}, {
"id": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.Therapieempfehlung.TherapeutischeStrategie",
"max": "1",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.Therapieempfehlung.TherapeutischeStrategie",
"type": [ {
"code": "code"
} ],
"short": "Therapeutische Strategie",
"definition": "Therapeutische Strategie (z.B. zielgerichtete Therapie, Immuntherapie, Chemotherapie, supportive Therapie)"
}, {
"id": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.PraeventiveUntersuchungen",
"max": "*",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.PraeventiveUntersuchungen",
"type": [ {
"code": "BackboneElement"
} ],
"short": "Präventive Maßnahmen",
"definition": "Präventive Maßnahmen"
}, {
"id": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.PraeventiveUntersuchungen.Identifier",
"max": "1",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.PraeventiveUntersuchungen.Identifier",
"type": [ {
"code": "string"
} ],
"short": "Identifier",
"definition": "interner Identifikator der präventiven Maßnahme"
}, {
"id": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.PraeventiveUntersuchungen.ArtUntersuchung",
"max": "1",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologiePlan.PraeventiveUntersuchungen.ArtUntersuchung",
"type": [ {
"code": "string"
} ],
"short": "Art der Untersuchung",
"definition": "Art der Untersuchung(z.B. Breast Imaging, MRI, MGR, US;Colonoscopy ; Esophago-gastro-duodenoscopy )"
}, {
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup",
"max": "*",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup",
"type": [ {
"code": "BackboneElement"
} ],
"short": "Follow-up und Umsetzung der Therapieempfehlung",
"definition": "Follow-up und Umsetzung der Therapieempfehlung"
}, {
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.Datum",
"max": "1",
"min": 1,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.Datum",
"type": [ {
"code": "date"
} ],
"short": "Datum",
"definition": "Datum des Follow-up"
}, {
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.MetachroneTumore",
"max": "*",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.MetachroneTumore",
"type": [ {
"code": "code"
} ],
"short": "Auftreten Metachroner Tumore",
"definition": "Auftreten metachroner Tumore ja/nein"
}, {
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.MetachroneDiagnose",
"max": "1",
"min": 1,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.MetachroneDiagnose",
"type": [ {
"code": "code"
} ],
"short": "Diagnose",
"definition": "Diagnose des metachronen Tumors laut ICD-10"
}, {
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.ECOG",
"max": "1",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.ECOG",
"type": [ {
"code": "code"
} ],
"short": "ECOG-Status",
"definition": "Eastern Cooperative Oncology Group (ECOG) Performance Status nach 0,1,2,3,4,5,unknown, not applicable"
}, {
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.Vitalstatus",
"max": "1",
"min": 1,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.Vitalstatus",
"type": [ {
"code": "code"
} ],
"short": "Vitalstatus",
"definition": "Vitalstatus des Patienten zum Zeitpunkt des Follow-ups (lebend, verstorben, unbekannt)"
}, {
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.LetzterKontakt",
"max": "1",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.LetzterKontakt",
"type": [ {
"code": "date"
} ],
"short": "Letzter Kontakt",
"definition": "Datum des letzten Kontakts"
}, {
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.Todesdatum",
"max": "1",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.Todesdatum",
"type": [ {
"code": "date"
} ],
"short": "Todesdatum",
"definition": "Datum des Todes"
}, {
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.Therapien",
"max": "*",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.Therapien",
"type": [ {
"code": "BackboneElement"
} ],
"short": "Therapien",
"definition": "Therapien"
}, {
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.Therapien.reference",
"max": "1",
"min": 1,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.Therapien.reference",
"type": [ {
"code": "string"
} ],
"short": "Referenz Studien-/ Therapieempfehlung",
"definition": "Referenz auf Studien- / Therapieempfehlung"
}, {
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.Therapien.TherapieStart",
"max": "1",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.Therapien.TherapieStart",
"type": [ {
"code": "date"
} ],
"short": "Startdatum",
"definition": "Startdatum der Therapie"
}, {
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.Therapien.TherapieEnde",
"max": "1",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.Therapien.TherapieEnde",
"type": [ {
"code": "date"
} ],
"short": "Enddatum",
"definition": "Enddatum der Therapie"
}, {
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.Therapien.TherapieWirkstoff",
"max": "*",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.Therapien.TherapieWirkstoff",
"type": [ {
"code": "code"
} ],
"short": "Wirkstoff",
"definition": "Wirkstoff der Therapie nach ATC oder Text bei nicht-ATC-Wirkstoffen"
}, {
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.Therapien.TherapieAnsprechen",
"max": "1",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.Therapien.TherapieAnsprechen",
"type": [ {
"code": "code"
} ],
"short": "Ansprechen",
"definition": "Therapieansprechen der Therapie (PD: Progression, SD:Stabile Erkrankung, PR:Partielle Remission, CR:Komplette Remission)"
}, {
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.Therapien.TherapieAnsprechenDatum",
"max": "1",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.Therapien.TherapieAnsprechenDatum",
"type": [ {
"code": "date"
} ],
"short": "Datum",
"definition": "Datum des Ansprechens der Vortherapie"
}, {
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.Therapien.TherapieEndeGrund",
"max": "1",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.Therapien.TherapieEndeGrund",
"type": [ {
"code": "code"
} ],
"short": "Ende der Therapie",
"definition": "Grund für das Ende der Vortherapie"
}, {
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.Therapien.DatenquelleTherapieansprechen",
"max": "1",
"min": 1,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.Therapien.DatenquelleTherapieansprechen",
"type": [ {
"code": "string"
} ],
"short": "Datenquelle Therapieansprechen",
"definition": "Datenquelle des Therapieansprechens (z.B. Arztbrief, Entlassungsbericht, Tumordokumentation)"
}, {
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.PraeventiveMassnahmen",
"max": "*",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.PraeventiveMassnahmen",
"type": [ {
"code": "BackboneElement"
} ],
"short": "Präventive Maßnahmen",
"definition": "Präventive Maßnahmen"
}, {
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.PraeventiveMassnahmen.reference",
"max": "1",
"min": 1,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.PraeventiveMassnahmen.reference",
"type": [ {
"code": "string"
} ],
"short": "Referenz präventive Maßnahme",
"definition": "interne Referenz auf präventive Maßnahme"
}, {
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.PraeventiveMassnahmen.preventiveMeasureResult",
"max": "1",
"min": 1,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.PraeventiveMassnahmen.preventiveMeasureResult",
"type": [ {
"code": "string"
} ],
"short": "Ergebnis der präventiven Maßnahme",
"definition": "Ergebnis der präventiven Maßnahme (z.B. ohne Befund, benigner Befund, Malignom, unklar)"
}, {
"id": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.PraeventiveMassnahmen.preventiveMeasureDate",
"max": "1",
"min": 0,
"path": "mii-lm-mvgenomseq-onkologie.OnkologieFollowup.PraeventiveMassnahmen.preventiveMeasureDate",
"type": [ {
"code": "date"
} ],
"short": "Datum der präventiven Maßnahme",
"definition": "Datum der präventiven Maßnahme"
} ]
},
"contact": [ {
"telecom": [ {
"value": "https://www.medizininformatik-initiative.de",
"system": "url"
} ]
} ],
"baseDefinition": "http://hl7.org/fhir/StructureDefinition/Element"
}