{
  "description": "Die Sequenz umfasst Informationen zu einer biologischen Sequenz, hier DNA-Sequenz. Es kann sich hierbei auch um Sequenzrohdaten oder assemblierte Daten handeln, jeweils mit den dazugehörigen Metadaten (z.B. Datum der Probennahme, Sequenzierungsgerät, Adapter für die Library Preparation, Upload in eine Online-Datenbank (Repositorium), etc.) handeln.",
  "_filename": "StructureDefinition-Sequence.json",
  "package_name": "rki.demis.igs",
  "date": "2024-11-26",
  "derivation": "constraint",
  "publisher": null,
  "fhirVersion": "4.0.1",
  "name": "Sequence",
  "abstract": false,
  "type": "MolecularSequence",
  "experimental": null,
  "resourceType": "StructureDefinition",
  "title": "Sequenz",
  "package_version": "3.0.0",
  "status": "active",
  "id": "6c4447ef-09f8-4edd-bcb0-2a80d8147816",
  "kind": "resource",
  "url": "https://demis.rki.de/fhir/igs/StructureDefinition/Sequence",
  "version": "3.0.1",
  "differential": {
    "element": [ {
      "id": "MolecularSequence.meta",
      "min": 1,
      "path": "MolecularSequence.meta",
      "mustSupport": true
    }, {
      "id": "MolecularSequence.meta.profile",
      "max": "1",
      "min": 1,
      "path": "MolecularSequence.meta.profile",
      "mustSupport": true,
      "fixedCanonical": "https://demis.rki.de/fhir/igs/StructureDefinition/Sequence"
    }, {
      "id": "MolecularSequence.extension",
      "min": 1,
      "path": "MolecularSequence.extension",
      "slicing": {
        "rules": "open",
        "discriminator": [ {
          "path": "url",
          "type": "value"
        } ]
      },
      "mustSupport": true
    }, {
      "path": "MolecularSequence.extension",
      "min": 0,
      "definition": "Person/Labor, die/das verantwortlich für die Sequenz ist",
      "isModifier": false,
      "short": "Person/Labor, die/das verantwortlich für die Sequenz ist",
      "type": [ {
        "code": "Extension",
        "profile": [ "https://demis.rki.de/fhir/igs/StructureDefinition/SequenceAuthor" ]
      } ],
      "mustSupport": true,
      "sliceName": "sequenceAuthor",
      "max": "1",
      "id": "MolecularSequence.extension:sequenceAuthor"
    }, {
      "path": "MolecularSequence.extension",
      "min": 0,
      "definition": "Grund der Sequenzierung",
      "isModifier": false,
      "short": "Grund der Sequenzierung",
      "type": [ {
        "code": "Extension",
        "profile": [ "https://demis.rki.de/fhir/igs/StructureDefinition/SequencingReason" ]
      } ],
      "mustSupport": true,
      "sliceName": "sequencingReason",
      "max": "1",
      "id": "MolecularSequence.extension:sequencingReason"
    }, {
      "path": "MolecularSequence.extension",
      "min": 1,
      "definition": "Referenz auf die Sequenz",
      "isModifier": false,
      "short": "Referenz auf die Sequenz",
      "type": [ {
        "code": "Extension",
        "profile": [ "https://demis.rki.de/fhir/igs/StructureDefinition/SequenceDocumentReference" ]
      } ],
      "mustSupport": true,
      "sliceName": "sequenceDocumentReference",
      "id": "MolecularSequence.extension:sequenceDocumentReference"
    }, {
      "id": "MolecularSequence.identifier",
      "max": "1",
      "min": 1,
      "path": "MolecularSequence.identifier",
      "short": "Laboreigener Identifier der Probe",
      "definition": "Eineindeutiger Identifier der Probe, die vom einreichenden Labor verwendet wird.",
      "mustSupport": true
    }, {
      "id": "MolecularSequence.type",
      "path": "MolecularSequence.type",
      "short": "Typ der Sequenz",
      "fixedCode": "dna",
      "definition": "Für DEMIS ist der Typ grundsätzlich mit dem Wert „dna“ zu belegen.",
      "mustSupport": true
    }, {
      "id": "MolecularSequence.patient",
      "max": "0",
      "path": "MolecularSequence.patient"
    }, {
      "id": "MolecularSequence.specimen",
      "min": 1,
      "path": "MolecularSequence.specimen",
      "type": [ {
        "code": "Reference",
        "aggregation": [ "bundled" ],
        "targetProfile": [ "https://demis.rki.de/fhir/igs/StructureDefinition/SpecimenSequence" ]
      } ],
      "short": "Verweis auf die Sequenz-Probe",
      "definition": "Verweis auf die Sequenz-Probe",
      "mustSupport": true
    }, {
      "id": "MolecularSequence.specimen.reference",
      "min": 1,
      "path": "MolecularSequence.specimen.reference",
      "mustSupport": true
    }, {
      "id": "MolecularSequence.device",
      "min": 1,
      "path": "MolecularSequence.device",
      "type": [ {
        "code": "Reference",
        "aggregation": [ "bundled" ],
        "targetProfile": [ "https://demis.rki.de/fhir/igs/StructureDefinition/SequencingDevice" ]
      } ],
      "short": "Verweis auf das Sequenziergerät",
      "definition": "Verweis auf das Sequenziergerät",
      "mustSupport": true
    }, {
      "id": "MolecularSequence.device.reference",
      "min": 1,
      "path": "MolecularSequence.device.reference",
      "mustSupport": true
    }, {
      "id": "MolecularSequence.performer",
      "min": 1,
      "path": "MolecularSequence.performer",
      "type": [ {
        "code": "Reference",
        "aggregation": [ "bundled" ],
        "targetProfile": [ "https://demis.rki.de/fhir/StructureDefinition/NotifierFacility" ]
      } ],
      "short": "Verweis auf die Melder-Einrichtung",
      "definition": "Verweis auf die Melder-Einrichtung",
      "mustSupport": true
    }, {
      "id": "MolecularSequence.performer.reference",
      "min": 1,
      "path": "MolecularSequence.performer.reference",
      "mustSupport": true
    }, {
      "id": "MolecularSequence.quantity",
      "max": "0",
      "path": "MolecularSequence.quantity"
    }, {
      "id": "MolecularSequence.referenceSeq",
      "max": "0",
      "path": "MolecularSequence.referenceSeq"
    }, {
      "id": "MolecularSequence.variant",
      "max": "0",
      "path": "MolecularSequence.variant"
    }, {
      "id": "MolecularSequence.observedSeq",
      "max": "0",
      "path": "MolecularSequence.observedSeq"
    }, {
      "id": "MolecularSequence.quality",
      "max": "0",
      "path": "MolecularSequence.quality"
    }, {
      "id": "MolecularSequence.readCoverage",
      "max": "0",
      "path": "MolecularSequence.readCoverage"
    }, {
      "id": "MolecularSequence.repository",
      "path": "MolecularSequence.repository",
      "short": "Repositorium, in welches die Sequenz hochgeladen wird",
      "definition": "Repositorium, in welches die Sequenz hochgeladen wird",
      "mustSupport": true
    }, {
      "id": "MolecularSequence.repository.extension",
      "min": 1,
      "path": "MolecularSequence.repository.extension",
      "slicing": {
        "rules": "open",
        "discriminator": [ {
          "path": "url",
          "type": "value"
        } ]
      },
      "mustSupport": true
    }, {
      "path": "MolecularSequence.repository.extension",
      "min": 0,
      "definition": "Datum des Sequenz-Uploads",
      "isModifier": false,
      "short": "Datum des Sequenz-Uploads",
      "type": [ {
        "code": "Extension",
        "profile": [ "https://demis.rki.de/fhir/igs/StructureDefinition/SequenceUploadDate" ]
      } ],
      "mustSupport": true,
      "sliceName": "sequenceUploadDate",
      "max": "1",
      "id": "MolecularSequence.repository.extension:sequenceUploadDate"
    }, {
      "path": "MolecularSequence.repository.extension",
      "min": 0,
      "definition": "Verantwortliche/es Person/Labor für den Sequenz-Upload.",
      "isModifier": false,
      "short": "Verantwortliche/es Person/Labor für den Sequenz-Upload",
      "type": [ {
        "code": "Extension",
        "profile": [ "https://demis.rki.de/fhir/igs/StructureDefinition/SequenceUploadSubmitter" ]
      } ],
      "mustSupport": true,
      "sliceName": "sequenceUploadSubmitter",
      "max": "1",
      "id": "MolecularSequence.repository.extension:sequenceUploadSubmitter"
    }, {
      "path": "MolecularSequence.repository.extension",
      "min": 1,
      "definition": "Status des Sequenz-Uploads.",
      "isModifier": false,
      "short": "Status des Sequenz-Uploads",
      "type": [ {
        "code": "Extension",
        "profile": [ "https://demis.rki.de/fhir/igs/StructureDefinition/SequenceUploadStatus" ]
      } ],
      "mustSupport": true,
      "sliceName": "sequenceUploadStatus",
      "max": "1",
      "id": "MolecularSequence.repository.extension:sequenceUploadStatus"
    }, {
      "id": "MolecularSequence.repository.url",
      "path": "MolecularSequence.repository.url",
      "short": "Hyperlink auf die Sequenz im Repositorium",
      "definition": "Hyperlink auf die Sequenz im Repositorium.",
      "mustSupport": true
    }, {
      "id": "MolecularSequence.repository.name",
      "min": 1,
      "path": "MolecularSequence.repository.name",
      "short": "Name des Repositoriums",
      "binding": {
        "strength": "required",
        "valueSet": "https://demis.rki.de/fhir/igs/ValueSet/repositoryName"
      },
      "definition": "Name des Repositoriums, in welches die Sequenz hochgeladen wird. Der Wert muss entsprechend des vom RKI definierten ValueSets https://demis.rki.de/fhir/igs/ValueSet/repositoryName dargestellt werden.",
      "mustSupport": true
    }, {
      "id": "MolecularSequence.repository.datasetId",
      "path": "MolecularSequence.repository.datasetId",
      "short": "Identifier der Sequenz im Repositorium",
      "definition": "Identifier der Sequenz im Repositorium.",
      "mustSupport": true
    }, {
      "id": "MolecularSequence.pointer",
      "max": "0",
      "path": "MolecularSequence.pointer"
    }, {
      "id": "MolecularSequence.structureVariant",
      "max": "0",
      "path": "MolecularSequence.structureVariant"
    } ]
  },
  "baseDefinition": "http://hl7.org/fhir/StructureDefinition/MolecularSequence"
}