description: RNA Seq
package_name: de.medizininformatikinitiative.kerndatensatz.mtb
derivation: constraint
name: MII_PR_MTB_RNA_Seq
type: Observation
elements:
  meta:
    mustSupport: true
    index: 0
    elements:
      profile: {mustSupport: true, index: 1}
  focus:
    type: Reference
    mustSupport: true
    refers: ['https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-pr-mtb-diagnose-primaertumor', 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-diagnose-primaertumor']
    index: 2
  component:
    short: Gen
    _short:
      extension:
      - url: http://hl7.org/fhir/StructureDefinition/translation
        extension:
        - {url: lang, valueCode: de-DE}
        - {url: content, valueString: Gen}
      - url: http://hl7.org/fhir/StructureDefinition/translation
        extension:
        - {url: lang, valueCode: en}
        - {url: content, valueString: Gene}
    index: 3
    slicing:
      slices:
        gene-studied:
          match: {}
          schema:
            short: Gen
            _short:
              extension:
              - url: http://hl7.org/fhir/StructureDefinition/translation
                extension:
                - {url: lang, valueCode: de-DE}
                - {url: content, valueString: Gen}
              - url: http://hl7.org/fhir/StructureDefinition/translation
                extension:
                - {url: lang, valueCode: en}
                - {url: content, valueString: Gene}
            index: 3
        variation-code:
          match: {}
          schema:
            short: Entrez ID & Ensemble ID
            _short:
              extension:
              - url: http://hl7.org/fhir/StructureDefinition/translation
                extension:
                - {url: lang, valueCode: de-DE}
                - {url: content, valueString: Entrez ID und Ensemble ID}
              - url: http://hl7.org/fhir/StructureDefinition/translation
                extension:
                - {url: lang, valueCode: en}
                - {url: content, valueString: Entrez ID and Ensemble ID}
            array: true
            max: 2
            index: 4
          max: 2
        transcript-id:
          match: {}
          schema:
            short: Transcript ID
            _short:
              extension:
              - url: http://hl7.org/fhir/StructureDefinition/translation
                extension:
                - {url: lang, valueCode: de-DE}
                - {url: content, valueString: Transkript-ID}
              - url: http://hl7.org/fhir/StructureDefinition/translation
                extension:
                - {url: lang, valueCode: en}
                - {url: content, valueString: Transcript ID}
            mustSupport: true
            index: 5
            elements:
              value:
                choices: [valueCodeableConcept]
                index: 7
              valueCodeableConcept: {type: CodeableConcept, choiceOf: value, index: 8}
        transcripts-per-million:
          match: {}
          schema:
            short: Transcripts per million
            _short:
              extension:
              - url: http://hl7.org/fhir/StructureDefinition/translation
                extension:
                - {url: lang, valueCode: de-DE}
                - {url: content, valueString: Transkripte pro Million}
              - url: http://hl7.org/fhir/StructureDefinition/translation
                extension:
                - {url: lang, valueCode: en}
                - {url: content, valueString: Transcripts per million}
            mustSupport: true
            index: 9
            elements:
              value:
                choices: [valueRatio]
                index: 11
              valueRatio: {type: Ratio, choiceOf: value, index: 12}
              value[x]:
                elements:
                  denominator:
                    elements:
                      value:
                        pattern: {type: Decimal, value: 1000000}
                        index: 13
        tissue-corrected-expression:
          match: {}
          schema:
            short: Tissue corrected expression
            _short:
              extension:
              - url: http://hl7.org/fhir/StructureDefinition/translation
                extension:
                - {url: lang, valueCode: de-DE}
                - {url: content, valueString: Gewebekorrigierte Expression}
              - url: http://hl7.org/fhir/StructureDefinition/translation
                extension:
                - {url: lang, valueCode: en}
                - {url: content, valueString: Tissue corrected expression}
            mustSupport: true
            index: 14
            elements:
              value:
                choices: [valueBoolean]
                index: 16
              valueBoolean: {type: boolean, choiceOf: value, index: 17}
        raw-counts:
          match: {}
          schema:
            short: Raw counts
            _short:
              extension:
              - url: http://hl7.org/fhir/StructureDefinition/translation
                extension:
                - {url: lang, valueCode: de-DE}
                - {url: content, valueString: Rohzaehlungen}
              - url: http://hl7.org/fhir/StructureDefinition/translation
                extension:
                - {url: lang, valueCode: en}
                - {url: content, valueString: Raw counts}
            mustSupport: true
            index: 18
            elements:
              value:
                choices: [valueQuantity]
                index: 20
              valueQuantity: {type: Quantity, choiceOf: value, index: 21}
        library-size:
          match: {}
          schema:
            short: Library size
            _short:
              extension:
              - url: http://hl7.org/fhir/StructureDefinition/translation
                extension:
                - {url: lang, valueCode: de-DE}
                - {url: content, valueString: Bibliotheksgroesse}
              - url: http://hl7.org/fhir/StructureDefinition/translation
                extension:
                - {url: lang, valueCode: en}
                - {url: content, valueString: Library size}
            mustSupport: true
            index: 22
            elements:
              value:
                choices: [valueQuantity]
                index: 24
              valueQuantity: {type: Quantity, choiceOf: value, index: 25}
        cohort-ranking:
          match: {}
          schema:
            short: Cohort ranking
            _short:
              extension:
              - url: http://hl7.org/fhir/StructureDefinition/translation
                extension:
                - {url: lang, valueCode: de-DE}
                - {url: content, valueString: Kohortenranking}
              - url: http://hl7.org/fhir/StructureDefinition/translation
                extension:
                - {url: lang, valueCode: en}
                - {url: content, valueString: Cohort ranking}
            mustSupport: true
            index: 26
            elements:
              value:
                choices: [valueQuantity]
                index: 28
              valueQuantity: {type: Quantity, choiceOf: value, index: 29}
package_version: 2026.0.1
class: profile
kind: resource
url: https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-pr-mtb-rna-seq
base: https://www.medizininformatik-initiative.de/fhir/ext/modul-molgen/StructureDefinition/variante
version: 2026.0.1