{
  "description": "Indicates the histology of the tumor based on the current ICD-O-3 classification",
  "_filename": "StructureDefinition-cce-core-Observation-Histology.json",
  "package_name": "cce.fhir.minimal",
  "date": null,
  "derivation": "constraint",
  "publisher": null,
  "fhirVersion": "4.0.1",
  "name": "Histology",
  "abstract": false,
  "type": "Observation",
  "experimental": null,
  "resourceType": "StructureDefinition",
  "title": null,
  "package_version": "0.3.0",
  "status": "draft",
  "id": "67d78b1a-afc2-4255-bf25-a8b1c56a6b0c",
  "kind": "resource",
  "url": "https://www.cancercoreeurope.eu/fhir/StructureDefinition/cce-core-Observation-Histology",
  "version": "0.0.1",
  "differential": {
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      "id": "Observation.status",
      "path": "Observation.status",
      "mustSupport": true
    }, {
      "id": "Observation.code",
      "path": "Observation.code",
      "mustSupport": true
    }, {
      "id": "Observation.code.coding.system",
      "path": "Observation.code.coding.system",
      "fixedUri": "http://loinc.org"
    }, {
      "id": "Observation.code.coding.code",
      "path": "Observation.code.coding.code",
      "fixedCode": "59847-4"
    }, {
      "id": "Observation.subject",
      "min": 1,
      "path": "Observation.subject",
      "type": [ {
        "code": "Reference",
        "targetProfile": [ "https://www.cancercoreeurope.eu/fhir/StructureDefinition/cce-core-Patient-Patient", "https://www.cancercoreeurope.eu/fhir/StructureDefinition/cce-core-Patient-Pseudonym" ]
      } ],
      "mustSupport": true
    }, {
      "id": "Observation.focus",
      "path": "Observation.focus",
      "type": [ {
        "code": "Reference",
        "targetProfile": [ "http://hl7.org/fhir/StructureDefinition/Resource", "https://www.cancercoreeurope.eu/fhir/StructureDefinition/cce-core-Condition-Primarydiagnosis" ]
      } ],
      "mustSupport": true
    }, {
      "id": "Observation.effective[x]",
      "path": "Observation.effective[x]",
      "type": [ {
        "code": "dateTime"
      } ],
      "short": "effectiveDateTime",
      "mapping": [ {
        "map": "Histology:Histologydate",
        "comment": "Histology:Histologydate",
        "identity": "ADT-GEKID"
      }, {
        "map": "urn:adt:dataelement:35:1",
        "identity": "ISO-11179"
      } ],
      "mustSupport": true
    }, {
      "id": "Observation.performer",
      "path": "Observation.performer",
      "type": [ {
        "code": "Reference",
        "targetProfile": [ "https://www.cancercoreeurope.eu/fhir/StructureDefinition/cce-core-Organization-Organisation" ]
      } ]
    }, {
      "id": "Observation.value[x]",
      "min": 1,
      "path": "Observation.value[x]",
      "type": [ {
        "code": "CodeableConcept"
      } ],
      "mustSupport": true
    }, {
      "id": "Observation.value[x].coding",
      "max": "1",
      "min": 1,
      "path": "Observation.value[x].coding",
      "mustSupport": true
    }, {
      "id": "Observation.value[x].coding.system",
      "min": 1,
      "path": "Observation.value[x].coding.system",
      "short": "ICD-O-3",
      "fixedUri": "urn:oid:2.16.840.1.113883.6.43.1",
      "definition": "International Classification of Diseases for Oncology, version 3",
      "mustSupport": true
    }, {
      "id": "Observation.value[x].coding.version",
      "min": 1,
      "path": "Observation.value[x].coding.version",
      "short": "ICD-O Catalogue Morphology (Version)",
      "binding": {
        "strength": "extensible",
        "valueSet": "https://www.cancercoreeurope.eu/fhir/core/ValueSet/ICDOVersionVS",
        "description": "ICD-O-3 Version"
      },
      "mapping": [ {
        "map": "Histology:Morphology_ICD_O_Version",
        "comment": "Histology:Morphology_ICD_O_Version",
        "identity": "ADT-GEKID"
      }, {
        "map": "urn:dktk:dataelement:8:2",
        "comment": "urn:dktk:dataelement:8:2",
        "identity": "ISO-11179"
      } ],
      "definition": "Catalog version of the ICD-O",
      "mustSupport": true
    }, {
      "id": "Observation.value[x].coding.code",
      "min": 1,
      "path": "Observation.value[x].coding.code",
      "short": "Morphology",
      "binding": {
        "strength": "required",
        "valueSet": "https://www.cancercoreeurope.eu/fhir/core/ValueSet/MorphologyICDO3VS",
        "description": "ICD-O-3 Morphology"
      },
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        "map": "Histology:Morphology_Code",
        "comment": "Histology:Morphology_Code",
        "identity": "ADT-GEKID"
      }, {
        "map": "urn:dktk:dataelement:7:2",
        "comment": "urn:dktk:dataelement:7:2",
        "identity": "ISO-11179"
      } ],
      "definition": "Indicates the histology of the tumor based on the current ICD-O-3 classification",
      "mustSupport": true
    }, {
      "id": "Observation.value[x].text",
      "path": "Observation.value[x].text",
      "mapping": [ {
        "map": "Histology.Morphology_Freetext",
        "comment": "Histology.Morphology_Freetext",
        "identity": "ADT-GEKID"
      }, {
        "map": "urn:adt:dataelement:39:1",
        "identity": "ISO-11179"
      } ],
      "mustSupport": true
    }, {
      "id": "Observation.specimen",
      "path": "Observation.specimen",
      "type": [ {
        "code": "Reference",
        "targetProfile": [ "https://fhir.bbmri.de/StructureDefinition/Specimen" ]
      } ]
    }, {
      "id": "Observation.specimen.reference",
      "min": 1,
      "path": "Observation.specimen.reference"
    }, {
      "id": "Observation.hasMember",
      "path": "Observation.hasMember",
      "slicing": {
        "rules": "open",
        "discriminator": [ {
          "path": "reference",
          "type": "type"
        } ]
      },
      "mustSupport": true
    }, {
      "id": "Observation.hasMember:Grading",
      "max": "1",
      "path": "Observation.hasMember",
      "type": [ {
        "code": "Reference",
        "targetProfile": [ "https://www.cancercoreeurope.eu/fhir/StructureDefinition/cce-core-Observation-Grading" ]
      } ],
      "sliceName": "Grading",
      "mustSupport": true
    }, {
      "id": "Observation.hasMember:NumberOfLymphNodesExamined",
      "max": "1",
      "path": "Observation.hasMember",
      "type": [ {
        "code": "Reference",
        "targetProfile": [ "https://www.cancercoreeurope.eu/fhir/StructureDefinition/cce-core-Observation-NumberOfLymphNodesExamined" ]
      } ],
      "sliceName": "NumberOfLymphNodesExamined",
      "mustSupport": true
    }, {
      "id": "Observation.hasMember:NumberOfLymphNodesAffected",
      "max": "1",
      "path": "Observation.hasMember",
      "type": [ {
        "code": "Reference",
        "targetProfile": [ "https://www.cancercoreeurope.eu/fhir/StructureDefinition/cce-core-Observation-NumberOfLymphNodesAffected" ]
      } ],
      "sliceName": "NumberOfLymphNodesAffected",
      "mustSupport": true
    }, {
      "id": "Observation.hasMember:NumberOfSentinelLymphNodesExamined",
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      "path": "Observation.hasMember",
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        "code": "Reference",
        "targetProfile": [ "https://www.cancercoreeurope.eu/fhir/StructureDefinition/cce-core-Observation-NumberOfSentinelLymphNodesExamined" ]
      } ],
      "sliceName": "NumberOfSentinelLymphNodesExamined",
      "mustSupport": true
    }, {
      "id": "Observation.hasMember:NumberOfSentinelLymphNodesAffected",
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        "code": "Reference",
        "targetProfile": [ "https://www.cancercoreeurope.eu/fhir/StructureDefinition/cce-core-Observation-NumberOfSentinelLymphNodesAffected" ]
      } ],
      "sliceName": "NumberOfSentinelLymphNodesAffected",
      "mustSupport": true
    } ]
  },
  "baseDefinition": "http://hl7.org/fhir/StructureDefinition/Observation"
}