description: Immunhistrchemistry report
package_name: de.medizininformatikinitiative.kerndatensatz.mtb
derivation: constraint
name: MII_PR_MTB_IMMUNOHISTOCHEMISTRY_HER2
type: Observation
elements:
  code:
    elements:
      coding:
        array: true
        min: 2
        index: 0
        slicing:
          slices:
            spezifisch:
              match: {}
              schema:
                mustSupport: true
                pattern:
                  type: Coding
                  value: {code: 18474-7, system: 'http://loinc.org', display: 'HER2 Ag [Presence] in Tissue by Immune stain'}
                _required: true
                index: 1
              min: 1
              max: 1
  value:
    choices: [valueCodeableConcept]
    index: 3
    slicing:
      slices:
        valueCodeableConcept:
          match: {}
          schema:
            choices: [valueCodeableConcept]
            index: 3
  valueCodeableConcept:
    type: CodeableConcept
    choiceOf: value
    index: 4
    slicing:
      slices:
        valueCodeableConcept:
          match: {}
          schema: {type: CodeableConcept, choiceOf: value, index: 4}
  value[x]:
    elements:
      coding:
        short: 0|1+|2+|3+|Indeterminate
        _short:
          extension:
          - url: http://hl7.org/fhir/StructureDefinition/translation
            extension:
            - {url: lang, valueCode: de-DE}
            - {url: content, valueString: 0|1+|2+|3+|Unbestimmt}
          - url: http://hl7.org/fhir/StructureDefinition/translation
            extension:
            - {url: lang, valueCode: en}
            - {url: content, valueString: 0|1+|2+|3+|Indeterminate}
        index: 5
        elements:
          system:
            pattern: {type: Uri, value: 'http://loinc.org'}
            index: 6
          code:
            binding: {strength: required, valueSet: 'http://loinc.org/vs/LL4396-9'}
            index: 7
  component:
    index: 8
    slicing:
      slices:
        gene-studied:
          match: {}
          schema:
            index: 8
            elements:
              value:
                pattern:
                  type: CodeableConcept
                  value:
                    coding:
                    - {code: 'HGNC:3430', system: 'http://www.genenames.org/geneId', display: ERBB2}
                choices: []
                index: 10
        biomarker-category:
          match: {}
          schema:
            index: 11
            elements:
              value[x]:
                elements:
                  coding:
                    pattern:
                      type: Coding
                      value: {code: immuneStain}
                    index: 12
package_version: 2026.0.1
class: profile
kind: resource
url: https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-pr-mtb-immunohistochemistry-her2
base: https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-pr-mtb-immunohistochemistry
version: 2026.0.1