description: 'Renal function can be determined by laboratory measurement of serum creatinine, from which the estimated glomerular\n(eGFR_MDMR) filtration rate can be calculated. Further input parameters are age, race and gender.  \nNote: The MDRD equation is hardly used any more and is replaced by the CKD-EPI equation.  \n[GFR Calculators:](http://www.mdrd.com/)'
package_name: ch.fhir.ig.ch-lab-report
derivation: constraint
name: ChLabObservation_eGFR_MDRD
type: Observation
elements:
  code:
    short: ValueSet for the allowed LOINC codes for eGFR MDRD among males and females
    binding: {strength: required, valueSet: 'http://fhir.ch/ig/ch-lab-report/ValueSet/observation-code-mdrd-male-female'}
    index: 0
  component:
    mustSupport: true
    array: true
    min: 2
    max: 2
    index: 1
    slicing:
      rules: closed
      ordered: false
      description: '2 possibilities: blacks - non-blacks'
      discriminator:
      - {path: code, type: value}
      min: 2
      max: 2
      slices:
        blacks:
          match:
            code:
              coding:
              - {code: 48643-1, system: 'http://loinc.org'}
          schema:
            short: eGFR_MDMR among blacks
            mustSupport: true
            _required: true
            index: 2
            extensions:
              value-r5: {url: null, index: 3}
            elements:
              extension:
                index: 3
                slicing:
                  slices:
                    value-r5:
                      match: {}
                      schema: {index: 3}
              code:
                short: eGFR_MDMR among blacks code
                pattern:
                  type: CodeableConcept
                  value:
                    coding:
                    - {code: 48643-1, system: 'http://loinc.org'}
                type: CodeableConcept
                index: 4
              value:
                short: Lab Result Component Value
                mustSupport: true
                choices: [valueQuantity]
                index: 6
                slicing:
                  slices:
                    valueQuantity:
                      match: {}
                      schema:
                        short: Lab Result Component Value
                        mustSupport: true
                        choices: [valueQuantity]
                        index: 6
              valueQuantity:
                type: Quantity
                short: Lab Result Component Value
                mustSupport: true
                choiceOf: value
                index: 7
                slicing:
                  slices:
                    valueQuantity:
                      match: {}
                      schema: {type: Quantity, short: Lab Result Component Value, mustSupport: true, choiceOf: value, index: 7}
              value[x]:
                elements:
                  value: {mustSupport: true, index: 8}
                  unit: {mustSupport: true, index: 9}
                  code:
                    pattern: {type: code, value: mL/min}
                    type: code
                    index: 10
                required: [unit, value]
        non-blacks:
          match:
            code:
              coding:
              - {code: 48642-3, system: 'http://loinc.org'}
          schema:
            short: eGFR_MDMR among non-blacks
            mustSupport: true
            _required: true
            index: 11
            extensions:
              value-r5: {url: null, index: 12}
            elements:
              extension:
                index: 12
                slicing:
                  slices:
                    value-r5:
                      match: {}
                      schema: {index: 12}
              code:
                short: eGFR_MDMR among non-blacks code
                pattern:
                  type: CodeableConcept
                  value:
                    coding:
                    - {code: 48642-3, system: 'http://loinc.org'}
                type: CodeableConcept
                index: 13
              value:
                short: Lab Result Component Value
                mustSupport: true
                choices: [valueQuantity]
                index: 15
                slicing:
                  slices:
                    valueQuantity:
                      match: {}
                      schema:
                        short: Lab Result Component Value
                        mustSupport: true
                        choices: [valueQuantity]
                        index: 15
              valueQuantity:
                type: Quantity
                short: Lab Result Component Value
                mustSupport: true
                choiceOf: value
                index: 16
                slicing:
                  slices:
                    valueQuantity:
                      match: {}
                      schema: {type: Quantity, short: Lab Result Component Value, mustSupport: true, choiceOf: value, index: 16}
              value[x]:
                elements:
                  value: {mustSupport: true, index: 17}
                  unit: {mustSupport: true, index: 18}
                  code:
                    pattern: {type: code, value: mL/min}
                    type: code
                    index: 19
                required: [unit, value]
package_version: 2.0.0-ballot
class: profile
kind: resource
url: http://fhir.ch/ig/ch-lab-report/StructureDefinition/ch-lab-observation-egfr-mdrd
base: http://fhir.ch/ig/ch-lab-report/StructureDefinition/ch-lab-observation-egfr
version: 2.0.0-ballot