description: An allergy or intolerance describes a patient’s tendency towards hypersensitivity to a certain substance, so that an unwanted physiological reaction is expected after exposure to the substance, while most people would not exhibit such a reaction to that amount. The observed physiological changes are usually the result of an immunological reaction.\r\nThe substances can be categorized as follows:\r\n* Medicine\r\n* Medicine category\r\n* Ingredient/addition\r\n* Nutrition\r\n* Environmental factor\r\n* Animal\r\n* Plants\r\n* Chemicals\r\n* Inhaled allergenic package_name: nictiz.fhir.nl.r4.zib2020 derivation: constraint name: ZibAllergyIntolerance abstract: true type: AllergyIntolerance elements: onset: choices: [] index: 12 slicing: rules: open discriminator: - {path: $this, type: type} min: null slices: onsetDateTime: match: {} schema: short: StartDateTime choices: [onsetDateTime] index: 14 category: short: AllergyCategory binding: {strength: required, valueSet: 'http://hl7.org/fhir/ValueSet/allergy-intolerance-category|4.0.1'} index: 2 extensions: allergyCategoryCodelist: url: http://nictiz.nl/fhir/StructureDefinition/ext-CodeSpecification type: Extension index: 3 elements: value: short: AllergyCategory choices: [] index: 5 elements: extension: type: Extension url: http://nictiz.nl/fhir/StructureDefinition/ext-CodeSpecification index: 3 slicing: slices: allergyCategoryCodelist: match: {} schema: type: Extension url: http://nictiz.nl/fhir/StructureDefinition/ext-CodeSpecification index: 3 elements: value: short: AllergyCategory choices: [] index: 5 criticality: short: Criticality binding: {strength: required, valueSet: 'http://hl7.org/fhir/ValueSet/allergy-intolerance-criticality|4.0.1'} index: 6 extensions: criticalExtentCodelist: url: http://nictiz.nl/fhir/StructureDefinition/ext-CodeSpecification type: Extension index: 7 elements: value: short: Criticality choices: [] index: 9 elements: extension: type: Extension url: http://nictiz.nl/fhir/StructureDefinition/ext-CodeSpecification index: 7 slicing: slices: criticalExtentCodelist: match: {} schema: type: Extension url: http://nictiz.nl/fhir/StructureDefinition/ext-CodeSpecification index: 7 elements: value: short: Criticality choices: [] index: 9 clinicalStatus: short: AllergyStatus binding: {strength: required, valueSet: 'http://hl7.org/fhir/ValueSet/allergyintolerance-clinical|4.0.1'} index: 0 note: index: 17 elements: text: {short: Comment, index: 18} code: short: CausativeAgent binding: {strength: required, valueSet: 'http://decor.nictiz.nl/fhir/ValueSet/2.16.840.1.113883.2.4.3.11.60.121.11.2--20200901000000'} index: 10 onsetDateTime: short: StartDateTime type: dateTime choiceOf: onset index: 15 slicing: slices: onsetDateTime: match: {} schema: {short: StartDateTime, type: dateTime, choiceOf: onset, index: 15} lastOccurrence: {short: LastReactionDateTime, index: 16} verificationStatus: short: AllergyStatus binding: {strength: required, valueSet: 'http://hl7.org/fhir/ValueSet/allergyintolerance-verification|4.0.1'} index: 1 reaction: short: Reaction index: 19 elements: substance: short: SpecificSubstance binding: {strength: required, valueSet: 'http://decor.nictiz.nl/fhir/ValueSet/2.16.840.1.113883.2.4.3.11.60.121.11.1--20200901000000'} index: 20 manifestation: short: Symptom binding: {strength: extensible, valueSet: 'http://decor.nictiz.nl/fhir/ValueSet/2.16.840.1.113883.2.4.3.11.60.40.2.8.2.5--20200901000000'} index: 21 description: {short: ReactionDescription, index: 22} onset: {short: ReactionTime, index: 23} severity: short: Severity binding: {strength: required, valueSet: 'http://hl7.org/fhir/ValueSet/reaction-event-severity|4.0.1'} index: 24 exposureRoute: short: RouteOfExposure binding: {strength: required, valueSet: 'http://decor.nictiz.nl/fhir/ValueSet/2.16.840.1.113883.2.4.3.11.60.40.2.8.2.12--20200901000000'} index: 25 package_version: 0.10.0-beta.1 class: profile kind: resource url: http://nictiz.nl/fhir/StructureDefinition/zib-AllergyIntolerance base: http://hl7.org/fhir/StructureDefinition/AllergyIntolerance version: null