{
  "description": "Stem Cell Transplantation.\\nMaturity Level: 2 - Ready for Review",
  "_filename": "StructureDefinition-StemCellTransplantation.json",
  "package_name": "hl7.eu.fhir.pcsp",
  "date": "2023-01-26T09:50:21+01:00",
  "derivation": "specialization",
  "publisher": "PanCareSurPass Project",
  "fhirVersion": "4.0.1",
  "jurisdiction": [ {
    "coding": [ {
      "code": "150",
      "system": "http://unstats.un.org/unsd/methods/m49/m49.htm",
      "display": "Europe"
    } ]
  } ],
  "name": "StemCellTransplantation",
  "mapping": [ {
    "uri": "http://hl7.org/v3",
    "name": "RIM Mapping",
    "identity": "rim"
  }, {
    "uri": "hl7.org/fhir/r4",
    "name": "StemCellTransplantation model to PCSP HL7 FHIR R4 Profiles",
    "identity": "fhir"
  } ],
  "abstract": false,
  "type": "http://hl7.eu/fhir/ig/pcsp/StructureDefinition/StemCellTransplantation",
  "experimental": null,
  "resourceType": "StructureDefinition",
  "title": "Stem Cell Transplantation",
  "package_version": "0.1.0",
  "snapshot": {
    "element": [ {
      "path": "StemCellTransplantation",
      "min": 0,
      "definition": "Stem Cell Transplantation.\nMaturity Level: 2 - Ready for Review",
      "isModifier": false,
      "short": "Stem Cell Transplantation",
      "mapping": [ {
        "map": "Procedure.conformsTo('http://hl7.eu/fhir/ig/pcsp/StructureDefinition/Procedure-sct-eu-pcsp')",
        "identity": "fhir"
      } ],
      "max": "*",
      "id": "StemCellTransplantation",
      "base": {
        "max": "*",
        "min": 0,
        "path": "Base"
      }
    }, {
      "path": "StemCellTransplantation.identifier",
      "min": 1,
      "definition": "Progressive SCT number",
      "short": "SCT Identifier",
      "mapping": [ {
        "map": ".identifier",
        "identity": "fhir"
      } ],
      "type": [ {
        "code": "Identifier"
      } ],
      "max": "*",
      "id": "StemCellTransplantation.identifier",
      "base": {
        "max": "*",
        "min": 1,
        "path": "StemCellTransplantation.identifier"
      }
    }, {
      "path": "StemCellTransplantation.relatedDiagnosis",
      "min": 1,
      "definition": "Progressive number of diagnosis",
      "short": "Progressive number of diagnosis",
      "mapping": [ {
        "map": ".reasonReference",
        "identity": "fhir"
      } ],
      "type": [ {
        "code": "Identifier"
      } ],
      "max": "*",
      "id": "StemCellTransplantation.relatedDiagnosis",
      "base": {
        "max": "*",
        "min": 1,
        "path": "StemCellTransplantation.relatedDiagnosis"
      }
    }, {
      "path": "StemCellTransplantation.relatedRelapse",
      "min": 1,
      "definition": "Progressive number of relapse/progression (after FLT)",
      "short": "Progressive number of relapse/progression (after FLT)",
      "mapping": [ {
        "map": ".reasonReference",
        "identity": "fhir"
      } ],
      "type": [ {
        "code": "Identifier"
      } ],
      "max": "*",
      "id": "StemCellTransplantation.relatedRelapse",
      "base": {
        "max": "*",
        "min": 1,
        "path": "StemCellTransplantation.relatedRelapse"
      }
    }, {
      "constraint": [ {
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        "human": "All FHIR elements must have a @value or children",
        "xpath": "@value|f:*|h:div",
        "source": "http://hl7.org/fhir/StructureDefinition/Element",
        "severity": "error",
        "expression": "hasValue() or (children().count() > id.count())"
      } ],
      "path": "StemCellTransplantation.istitutionOfTreatment",
      "min": 0,
      "definition": "Please Identify the institution were the procedure was performed",
      "short": "Institution of treatment",
      "mapping": [ {
        "map": "location.resolve().conformsTo(http://hl7.eu/fhir/ig/pcsp/StructureDefinition/Location-eu-pcsp)",
        "identity": "fhir"
      } ],
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        "code": "BackboneElement"
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        "identity": "rim"
      } ],
      "type": [ {
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        "extension": [ {
          "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
          "valueUrl": "string"
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      "representation": [ "xmlAttr" ],
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        "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
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        "discriminator": [ {
          "path": "url",
          "type": "value"
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      "type": [ {
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      "alias": [ "extensions", "user content" ],
      "max": "*",
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      "comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
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        "severity": "error",
        "expression": "extension.exists() != value.exists()"
      } ],
      "path": "StemCellTransplantation.istitutionOfTreatment.modifierExtension",
      "requirements": "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored.  This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](http://hl7.org/fhir/R4/extensibility.html#modifierExtension).",
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      "isModifier": true,
      "short": "Extensions that cannot be ignored even if unrecognized",
      "mapping": [ {
        "map": "N/A",
        "identity": "rim"
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        "code": "Extension"
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      "alias": [ "extensions", "user content", "modifiers" ],
      "max": "*",
      "id": "StemCellTransplantation.istitutionOfTreatment.modifierExtension",
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      "base": {
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        "min": 0,
        "path": "BackboneElement.modifierExtension"
      },
      "isModifierReason": "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them",
      "isSummary": true
    }, {
      "path": "StemCellTransplantation.istitutionOfTreatment.description",
      "min": 0,
      "definition": "Institution description",
      "short": "Institution description",
      "mapping": [ {
        "map": "Location.description",
        "identity": "fhir"
      } ],
      "type": [ {
        "code": "string"
      } ],
      "max": "1",
      "id": "StemCellTransplantation.istitutionOfTreatment.description",
      "base": {
        "max": "1",
        "min": 0,
        "path": "StemCellTransplantation.istitutionOfTreatment.description"
      }
    }, {
      "path": "StemCellTransplantation.istitutionOfTreatment.name",
      "min": 0,
      "definition": "Institution name",
      "short": "Institution name",
      "mapping": [ {
        "map": "Location.name",
        "identity": "fhir"
      } ],
      "type": [ {
        "code": "string"
      } ],
      "max": "1",
      "id": "StemCellTransplantation.istitutionOfTreatment.name",
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        "max": "1",
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        "path": "StemCellTransplantation.istitutionOfTreatment.name"
      }
    }, {
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        "xpath": "@value|f:*|h:div",
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        "severity": "error",
        "expression": "hasValue() or (children().count() > id.count())"
      } ],
      "path": "StemCellTransplantation.istitutionOfTreatment.address",
      "min": 0,
      "definition": "Institution address",
      "short": "Institution address",
      "mapping": [ {
        "map": "Location.address.city",
        "identity": "fhir"
      } ],
      "type": [ {
        "code": "BackboneElement"
      } ],
      "max": "1",
      "id": "StemCellTransplantation.istitutionOfTreatment.address",
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    }, {
      "path": "StemCellTransplantation.istitutionOfTreatment.address.id",
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      "short": "Unique id for inter-element referencing",
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        "map": "n/a",
        "identity": "rim"
      } ],
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        "extension": [ {
          "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
          "valueUrl": "string"
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      } ],
      "representation": [ "xmlAttr" ],
      "max": "1",
      "id": "StemCellTransplantation.istitutionOfTreatment.address.id",
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        "path": "Element.id"
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      "isSummary": false
    }, {
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      "path": "StemCellTransplantation.istitutionOfTreatment.address.extension",
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      "alias": [ "extensions", "user content" ],
      "max": "*",
      "id": "StemCellTransplantation.istitutionOfTreatment.address.extension",
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        "severity": "error",
        "expression": "extension.exists() != value.exists()"
      } ],
      "path": "StemCellTransplantation.istitutionOfTreatment.address.modifierExtension",
      "requirements": "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored.  This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](http://hl7.org/fhir/R4/extensibility.html#modifierExtension).",
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      "isModifier": true,
      "short": "Extensions that cannot be ignored even if unrecognized",
      "mapping": [ {
        "map": "N/A",
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      } ],
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      "alias": [ "extensions", "user content", "modifiers" ],
      "max": "*",
      "id": "StemCellTransplantation.istitutionOfTreatment.address.modifierExtension",
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      "base": {
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        "min": 0,
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      },
      "isModifierReason": "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them",
      "isSummary": true
    }, {
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      "max": "1",
      "min": 0,
      "base": {
        "max": "1",
        "min": 0,
        "path": "StemCellTransplantation.istitutionOfTreatment.address.name"
      },
      "path": "StemCellTransplantation.istitutionOfTreatment.address.name",
      "type": [ {
        "code": "string"
      } ],
      "short": "Institution city",
      "definition": "Institution city"
    }, {
      "path": "StemCellTransplantation.istitutionOfTreatment.address.country",
      "min": 0,
      "definition": "Institution country",
      "short": "Institution country",
      "mapping": [ {
        "map": "Location.address.country",
        "identity": "fhir"
      } ],
      "type": [ {
        "code": "string"
      } ],
      "max": "1",
      "id": "StemCellTransplantation.istitutionOfTreatment.address.country",
      "base": {
        "max": "1",
        "min": 0,
        "path": "StemCellTransplantation.istitutionOfTreatment.address.country"
      }
    }, {
      "path": "StemCellTransplantation.date",
      "min": 0,
      "definition": "Date of the reinfusion of hematopoietic stem cells. If the date is unkown or partially missed insert the year at the best of your knowledge.",
      "short": "Date of transplant",
      "mapping": [ {
        "map": ".performedDateTime",
        "identity": "fhir"
      } ],
      "type": [ {
        "code": "dateTime"
      } ],
      "max": "*",
      "id": "StemCellTransplantation.date",
      "base": {
        "max": "*",
        "min": 0,
        "path": "StemCellTransplantation.date"
      }
    }, {
      "path": "StemCellTransplantation.transplantType",
      "min": 0,
      "definition": "Indicate if the transplant was autologous or allogeneic.\n1 = Autologous\n2 = Allogeneic\n-9922 = NK",
      "short": "Type of transplant",
      "mapping": [ {
        "map": ".code",
        "identity": "fhir"
      } ],
      "type": [ {
        "code": "CodeableConcept"
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      "max": "1",
      "id": "StemCellTransplantation.transplantType",
      "base": {
        "max": "1",
        "min": 0,
        "path": "StemCellTransplantation.transplantType"
      }
    }, {
      "path": "StemCellTransplantation.donorType",
      "min": 0,
      "definition": "Define the type of donor \nin case of allogenic transplant,\n1 = matched related\n2 = matched unrelated\n3 = mismatch related\n4 = mismatch unrelated\n5 = haplo-identical\n-9922 = NK\n\n1 = matched related ? sibling\n2 = matched related ? parent\n3 = matched related ? other (e.g. cousin)\n-9922 = NK",
      "short": "Type of donor",
      "mapping": [ {
        "map": "BiologicallyDerivedProduct .conformsTo('http://hl7.eu/fhir/ig/pcsp/StructureDefinition/BiologicallyDerivedProduct-sct-eu-pcsp').extension('http://hl7.eu/fhir/ig/pcsp/StructureDefinition/sct-donor-type').valueCodeableConcept",
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      "max": "1",
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      "base": {
        "max": "1",
        "min": 0,
        "path": "StemCellTransplantation.donorType"
      }
    }, {
      "path": "StemCellTransplantation.cellSource",
      "min": 0,
      "definition": "Indicate the source of cells\n1 = PBSC \n2 = Bone marrow\n3 = Cord\n-9922 = NK",
      "short": "Source of cells",
      "mapping": [ {
        "map": "BiologicallyDerivedProduct .conformsTo('http://hl7.eu/fhir/ig/pcsp/StructureDefinition/BiologicallyDerivedProduct-sct-eu-pcsp').extension('http://hl7.eu/fhir/ig/pcsp/StructureDefinition/sct-source-type').valueCodeableConcept",
        "identity": "fhir"
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      "type": [ {
        "code": "CodeableConcept"
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      "max": "1",
      "id": "StemCellTransplantation.cellSource",
      "base": {
        "max": "1",
        "min": 0,
        "path": "StemCellTransplantation.cellSource"
      }
    }, {
      "path": "StemCellTransplantation.conditioningRegimen",
      "min": 0,
      "definition": "Please list the drugs (name) and radiotherapy used or the conditioning regimen.  These drugs contribute to the calculation of cumulative doses received by the patient reported in the chemotherapy section.  Here it is requested only the names of the drugs and if possible the dosage used (only for possible information in the future).\nNo calculations are made on these data.",
      "short": "Conditioning regimen: drugs used",
      "mapping": [ {
        "map": "Procedure.conformsTo('http://hl7.eu/fhir/ig/pcsp/StructureDefinition/Procedure-sct-prophylaxis-eu-pcsp').where(reasonReference.resolve().conformTo('http://hl7.eu/fhir/ig/pcsp/StructureDefinition/Procedure-sct-eu-pcsp') ).text",
        "identity": "fhir"
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      "type": [ {
        "code": "string"
      } ],
      "max": "1",
      "id": "StemCellTransplantation.conditioningRegimen",
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        "path": "StemCellTransplantation.conditioningRegimen"
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    }, {
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      "path": "StemCellTransplantation.gvhd",
      "min": 0,
      "definition": "Graft Versus Host Disease",
      "short": "Graft Versus Host Disease",
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        "map": "Condition.conformsTo('http://hl7.eu/fhir/ig/pcsp/StructureDefinition/Condition-gvdh-eu-pcsp')",
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        "human": "Must have either extensions or value[x], not both",
        "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
        "source": "http://hl7.org/fhir/StructureDefinition/Extension",
        "severity": "error",
        "expression": "extension.exists() != value.exists()"
      } ],
      "path": "StemCellTransplantation.gvhd.extension",
      "min": 0,
      "definition": "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
      "isModifier": false,
      "short": "Additional content defined by implementations",
      "mapping": [ {
        "map": "n/a",
        "identity": "rim"
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      "slicing": {
        "rules": "open",
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        "discriminator": [ {
          "path": "url",
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      },
      "type": [ {
        "code": "Extension"
      } ],
      "alias": [ "extensions", "user content" ],
      "max": "*",
      "id": "StemCellTransplantation.gvhd.extension",
      "comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
      "base": {
        "max": "*",
        "min": 0,
        "path": "Element.extension"
      },
      "isSummary": false
    }, {
      "constraint": [ {
        "key": "ele-1",
        "human": "All FHIR elements must have a @value or children",
        "xpath": "@value|f:*|h:div",
        "source": "http://hl7.org/fhir/StructureDefinition/Element",
        "severity": "error",
        "expression": "hasValue() or (children().count() > id.count())"
      }, {
        "key": "ext-1",
        "human": "Must have either extensions or value[x], not both",
        "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
        "source": "http://hl7.org/fhir/StructureDefinition/Extension",
        "severity": "error",
        "expression": "extension.exists() != value.exists()"
      } ],
      "path": "StemCellTransplantation.gvhd.modifierExtension",
      "requirements": "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored.  This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](http://hl7.org/fhir/R4/extensibility.html#modifierExtension).",
      "min": 0,
      "definition": "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).",
      "isModifier": true,
      "short": "Extensions that cannot be ignored even if unrecognized",
      "mapping": [ {
        "map": "N/A",
        "identity": "rim"
      } ],
      "type": [ {
        "code": "Extension"
      } ],
      "alias": [ "extensions", "user content", "modifiers" ],
      "max": "*",
      "id": "StemCellTransplantation.gvhd.modifierExtension",
      "comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
      "base": {
        "max": "*",
        "min": 0,
        "path": "BackboneElement.modifierExtension"
      },
      "isModifierReason": "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them",
      "isSummary": true
    }, {
      "path": "StemCellTransplantation.gvhd.prophylaxis",
      "min": 0,
      "definition": "State if any GVHD prophylaxis was given. Details on the drug names used for GVHD prophylaxis should be listed in the chemotherapy section under 'immunotherapy').\n1 => Yes\n2 => No\n-9922 => NK   ",
      "short": "GVHD prophylaxis",
      "mapping": [ {
        "map": "Procedure.conformsTo('http://hl7.eu/fhir/ig/pcsp/StructureDefinition/Procedure-sct-prophylaxis-eu-pcsp').where(code = $sct#868254008 'GVHD (graft versus host disease) prophylaxis').exists()",
        "identity": "fhir"
      } ],
      "type": [ {
        "code": "CodeableConcept"
      } ],
      "max": "1",
      "id": "StemCellTransplantation.gvhd.prophylaxis",
      "base": {
        "max": "1",
        "min": 0,
        "path": "StemCellTransplantation.gvhd.prophylaxis"
      }
    }, {
      "constraint": [ {
        "key": "ele-1",
        "human": "All FHIR elements must have a @value or children",
        "xpath": "@value|f:*|h:div",
        "source": "http://hl7.org/fhir/StructureDefinition/Element",
        "severity": "error",
        "expression": "hasValue() or (children().count() > id.count())"
      } ],
      "path": "StemCellTransplantation.gvhd.acute",
      "min": 0,
      "definition": "GVHD Acute ",
      "short": "GVHD Acute",
      "mapping": [ {
        "map": ".where(code = http://snomed.info/sct#402355000 'Acute graft-versus-host disease')",
        "identity": "fhir"
      } ],
      "type": [ {
        "code": "BackboneElement"
      } ],
      "max": "1",
      "id": "StemCellTransplantation.gvhd.acute",
      "base": {
        "max": "1",
        "min": 0,
        "path": "StemCellTransplantation.gvhd.acute"
      }
    }, {
      "path": "StemCellTransplantation.gvhd.acute.id",
      "min": 0,
      "definition": "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
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      "short": "Unique id for inter-element referencing",
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        "identity": "rim"
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      "type": [ {
        "code": "http://hl7.org/fhirpath/System.String",
        "extension": [ {
          "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
          "valueUrl": "string"
        } ]
      } ],
      "representation": [ "xmlAttr" ],
      "max": "1",
      "id": "StemCellTransplantation.gvhd.acute.id",
      "base": {
        "max": "1",
        "min": 0,
        "path": "Element.id"
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      "isSummary": false
    }, {
      "constraint": [ {
        "key": "ele-1",
        "human": "All FHIR elements must have a @value or children",
        "xpath": "@value|f:*|h:div",
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        "severity": "error",
        "expression": "hasValue() or (children().count() > id.count())"
      }, {
        "key": "ext-1",
        "human": "Must have either extensions or value[x], not both",
        "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
        "source": "http://hl7.org/fhir/StructureDefinition/Extension",
        "severity": "error",
        "expression": "extension.exists() != value.exists()"
      } ],
      "path": "StemCellTransplantation.gvhd.acute.extension",
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      "definition": "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
      "isModifier": false,
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      "mapping": [ {
        "map": "n/a",
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      "slicing": {
        "rules": "open",
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        "discriminator": [ {
          "path": "url",
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        } ]
      },
      "type": [ {
        "code": "Extension"
      } ],
      "alias": [ "extensions", "user content" ],
      "max": "*",
      "id": "StemCellTransplantation.gvhd.acute.extension",
      "comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
      "base": {
        "max": "*",
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      "isSummary": false
    }, {
      "constraint": [ {
        "key": "ele-1",
        "human": "All FHIR elements must have a @value or children",
        "xpath": "@value|f:*|h:div",
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        "severity": "error",
        "expression": "hasValue() or (children().count() > id.count())"
      }, {
        "key": "ext-1",
        "human": "Must have either extensions or value[x], not both",
        "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
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        "severity": "error",
        "expression": "extension.exists() != value.exists()"
      } ],
      "path": "StemCellTransplantation.gvhd.acute.modifierExtension",
      "requirements": "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored.  This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](http://hl7.org/fhir/R4/extensibility.html#modifierExtension).",
      "min": 0,
      "definition": "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).",
      "isModifier": true,
      "short": "Extensions that cannot be ignored even if unrecognized",
      "mapping": [ {
        "map": "N/A",
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      "type": [ {
        "code": "Extension"
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      "alias": [ "extensions", "user content", "modifiers" ],
      "max": "*",
      "id": "StemCellTransplantation.gvhd.acute.modifierExtension",
      "comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
      "base": {
        "max": "*",
        "min": 0,
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      },
      "isModifierReason": "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them",
      "isSummary": true
    }, {
      "path": "StemCellTransplantation.gvhd.acute.status",
      "min": 1,
      "definition": "Please State if acute GVHD occurred\n1 => Yes\n2 => No\n-9922 => NK ",
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      "mapping": [ {
        "map": ".where(code = http://snomed.info/sct#402355000 'Acute graft-versus-host disease').exists()",
        "identity": "fhir"
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      "type": [ {
        "code": "CodeableConcept"
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      "max": "1",
      "id": "StemCellTransplantation.gvhd.acute.status",
      "base": {
        "max": "1",
        "min": 1,
        "path": "StemCellTransplantation.gvhd.acute.status"
      }
    }, {
      "path": "StemCellTransplantation.gvhd.acute.grade",
      "min": 1,
      "definition": "If yes, state the maximum grade of acute GVHD.\n\n1 => 1\n2 => 2\n3 => 3\n4 => 4\n-9922 => NK ",
      "short": "Grade",
      "mapping": [ {
        "map": ".stage.summary",
        "identity": "fhir"
      } ],
      "type": [ {
        "code": "CodeableConcept"
      } ],
      "max": "1",
      "id": "StemCellTransplantation.gvhd.acute.grade",
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        "max": "1",
        "min": 1,
        "path": "StemCellTransplantation.gvhd.acute.grade"
      }
    }, {
      "path": "StemCellTransplantation.gvhd.acute.startDate",
      "min": 0,
      "definition": "Define the starting date of GVHD. If the date is unkown or partially missed insert the year at the best of your knowledge.",
      "short": "Start date",
      "mapping": [ {
        "map": ".onsetDateTime",
        "identity": "fhir"
      } ],
      "type": [ {
        "code": "date"
      } ],
      "max": "1",
      "id": "StemCellTransplantation.gvhd.acute.startDate",
      "base": {
        "max": "1",
        "min": 0,
        "path": "StemCellTransplantation.gvhd.acute.startDate"
      }
    }, {
      "path": "StemCellTransplantation.gvhd.acute.endDate",
      "min": 0,
      "definition": "Define the ending date of GVHD. If the date is unkown or partially missed insert the year at the best of your knowledge.",
      "short": "End date",
      "mapping": [ {
        "map": ".abatementDateTime",
        "identity": "fhir"
      } ],
      "type": [ {
        "code": "date"
      } ],
      "max": "1",
      "id": "StemCellTransplantation.gvhd.acute.endDate",
      "base": {
        "max": "1",
        "min": 0,
        "path": "StemCellTransplantation.gvhd.acute.endDate"
      }
    }, {
      "constraint": [ {
        "key": "ele-1",
        "human": "All FHIR elements must have a @value or children",
        "xpath": "@value|f:*|h:div",
        "source": "http://hl7.org/fhir/StructureDefinition/Element",
        "severity": "error",
        "expression": "hasValue() or (children().count() > id.count())"
      } ],
      "path": "StemCellTransplantation.gvhd.chronic",
      "min": 0,
      "definition": "GVHD Chronic ",
      "short": "GVHD Chronic",
      "mapping": [ {
        "map": ".where(code = http://snomed.info/sct#402356004 'Chronic graft-versus-host disease')",
        "identity": "fhir"
      } ],
      "type": [ {
        "code": "BackboneElement"
      } ],
      "max": "1",
      "id": "StemCellTransplantation.gvhd.chronic",
      "base": {
        "max": "1",
        "min": 0,
        "path": "StemCellTransplantation.gvhd.chronic"
      }
    }, {
      "path": "StemCellTransplantation.gvhd.chronic.id",
      "min": 0,
      "definition": "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
      "isModifier": false,
      "short": "Unique id for inter-element referencing",
      "mapping": [ {
        "map": "n/a",
        "identity": "rim"
      } ],
      "type": [ {
        "code": "http://hl7.org/fhirpath/System.String",
        "extension": [ {
          "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
          "valueUrl": "string"
        } ]
      } ],
      "representation": [ "xmlAttr" ],
      "max": "1",
      "id": "StemCellTransplantation.gvhd.chronic.id",
      "base": {
        "max": "1",
        "min": 0,
        "path": "Element.id"
      },
      "isSummary": false
    }, {
      "constraint": [ {
        "key": "ele-1",
        "human": "All FHIR elements must have a @value or children",
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      }, {
        "key": "ext-1",
        "human": "Must have either extensions or value[x], not both",
        "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
        "source": "http://hl7.org/fhir/StructureDefinition/Extension",
        "severity": "error",
        "expression": "extension.exists() != value.exists()"
      } ],
      "path": "StemCellTransplantation.gvhd.chronic.extension",
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      },
      "type": [ {
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      "alias": [ "extensions", "user content" ],
      "max": "*",
      "id": "StemCellTransplantation.gvhd.chronic.extension",
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      "base": {
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    }, {
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      } ],
      "path": "StemCellTransplantation.gvhd.chronic.modifierExtension",
      "requirements": "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored.  This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](http://hl7.org/fhir/R4/extensibility.html#modifierExtension).",
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      "isModifier": true,
      "short": "Extensions that cannot be ignored even if unrecognized",
      "mapping": [ {
        "map": "N/A",
        "identity": "rim"
      } ],
      "type": [ {
        "code": "Extension"
      } ],
      "alias": [ "extensions", "user content", "modifiers" ],
      "max": "*",
      "id": "StemCellTransplantation.gvhd.chronic.modifierExtension",
      "comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
      "base": {
        "max": "*",
        "min": 0,
        "path": "BackboneElement.modifierExtension"
      },
      "isModifierReason": "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them",
      "isSummary": true
    }, {
      "path": "StemCellTransplantation.gvhd.chronic.status",
      "min": 1,
      "definition": "Please State if chronic GVHD occurred\n1 => Yes\n2 => No\n-9922 => NK ",
      "short": "GVHD Chronicstatus",
      "mapping": [ {
        "map": ".where(code = http://snomed.info/sct#402356004 'Chronic graft-versus-host disease').exists()",
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      "type": [ {
        "code": "CodeableConcept"
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      "max": "1",
      "id": "StemCellTransplantation.gvhd.chronic.status",
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        "max": "1",
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        "path": "StemCellTransplantation.gvhd.chronic.status"
      }
    }, {
      "path": "StemCellTransplantation.gvhd.chronic.grade",
      "min": 1,
      "definition": " If yes, state the maximum grade of chronic GVHD\n1 => Limited\n2 => Extensive\n-9922 => NK",
      "short": "Grade",
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        "map": ".stage.summary",
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      "type": [ {
        "code": "CodeableConcept"
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      "max": "1",
      "id": "StemCellTransplantation.gvhd.chronic.grade",
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        "max": "1",
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        "path": "StemCellTransplantation.gvhd.chronic.grade"
      }
    }, {
      "path": "StemCellTransplantation.gvhd.chronic.startDate",
      "min": 0,
      "definition": "Please Define the starting date of GVHD. If the date is unkown or partially missed insert the year at the best of your knowledge.",
      "short": "Start date",
      "mapping": [ {
        "map": ".onsetDateTime",
        "identity": "fhir"
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      "type": [ {
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      "max": "1",
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      "base": {
        "max": "1",
        "min": 0,
        "path": "StemCellTransplantation.gvhd.chronic.startDate"
      }
    }, {
      "path": "StemCellTransplantation.gvhd.chronic.endDate",
      "min": 0,
      "definition": "Please Define the ending date of GVHD. If the date is unkown or partially missed insert the year at the best of your knowledge.",
      "short": "End date",
      "mapping": [ {
        "map": ".abatementDateTime",
        "identity": "fhir"
      } ],
      "type": [ {
        "code": "date"
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      "max": "1",
      "id": "StemCellTransplantation.gvhd.chronic.endDate",
      "base": {
        "max": "1",
        "min": 0,
        "path": "StemCellTransplantation.gvhd.chronic.endDate"
      }
    }, {
      "path": "StemCellTransplantation.gvhd.organAffected",
      "min": 0,
      "definition": "Please List organs affected by GVHD",
      "short": "Organs affected",
      "mapping": [ {
        "map": ".bodySite",
        "identity": "fhir"
      } ],
      "type": [ {
        "code": "string"
      } ],
      "max": "*",
      "id": "StemCellTransplantation.gvhd.organAffected",
      "base": {
        "max": "*",
        "min": 0,
        "path": "StemCellTransplantation.gvhd.organAffected"
      }
    }, {
      "constraint": [ {
        "key": "ele-1",
        "human": "All FHIR elements must have a @value or children",
        "xpath": "@value|f:*|h:div",
        "source": "http://hl7.org/fhir/StructureDefinition/Element",
        "severity": "error",
        "expression": "hasValue() or (children().count() > id.count())"
      } ],
      "path": "StemCellTransplantation.bloodBeforeTransplant",
      "min": 0,
      "definition": "Blood before transplant ",
      "short": "Blood before transplant",
      "mapping": [ {
        "map": "Observation.conformsTo('http://hl7.eu/fhir/ig/pcsp/StructureDefinition/Observation-bld-abo-rh-eu-pcsp').where(effectiveTiming.code = #before-procedure)",
        "identity": "fhir"
      } ],
      "type": [ {
        "code": "BackboneElement"
      } ],
      "max": "1",
      "id": "StemCellTransplantation.bloodBeforeTransplant",
      "base": {
        "max": "1",
        "min": 0,
        "path": "StemCellTransplantation.bloodBeforeTransplant"
      }
    }, {
      "path": "StemCellTransplantation.bloodBeforeTransplant.id",
      "min": 0,
      "definition": "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
      "isModifier": false,
      "short": "Unique id for inter-element referencing",
      "mapping": [ {
        "map": "n/a",
        "identity": "rim"
      } ],
      "type": [ {
        "code": "http://hl7.org/fhirpath/System.String",
        "extension": [ {
          "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
          "valueUrl": "string"
        } ]
      } ],
      "representation": [ "xmlAttr" ],
      "max": "1",
      "id": "StemCellTransplantation.bloodBeforeTransplant.id",
      "base": {
        "max": "1",
        "min": 0,
        "path": "Element.id"
      },
      "isSummary": false
    }, {
      "constraint": [ {
        "key": "ele-1",
        "human": "All FHIR elements must have a @value or children",
        "xpath": "@value|f:*|h:div",
        "source": "http://hl7.org/fhir/StructureDefinition/Element",
        "severity": "error",
        "expression": "hasValue() or (children().count() > id.count())"
      }, {
        "key": "ext-1",
        "human": "Must have either extensions or value[x], not both",
        "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
        "source": "http://hl7.org/fhir/StructureDefinition/Extension",
        "severity": "error",
        "expression": "extension.exists() != value.exists()"
      } ],
      "path": "StemCellTransplantation.bloodBeforeTransplant.extension",
      "min": 0,
      "definition": "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
      "isModifier": false,
      "short": "Additional content defined by implementations",
      "mapping": [ {
        "map": "n/a",
        "identity": "rim"
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      "slicing": {
        "rules": "open",
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        "discriminator": [ {
          "path": "url",
          "type": "value"
        } ]
      },
      "type": [ {
        "code": "Extension"
      } ],
      "alias": [ "extensions", "user content" ],
      "max": "*",
      "id": "StemCellTransplantation.bloodBeforeTransplant.extension",
      "comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
      "base": {
        "max": "*",
        "min": 0,
        "path": "Element.extension"
      },
      "isSummary": false
    }, {
      "constraint": [ {
        "key": "ele-1",
        "human": "All FHIR elements must have a @value or children",
        "xpath": "@value|f:*|h:div",
        "source": "http://hl7.org/fhir/StructureDefinition/Element",
        "severity": "error",
        "expression": "hasValue() or (children().count() > id.count())"
      }, {
        "key": "ext-1",
        "human": "Must have either extensions or value[x], not both",
        "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
        "source": "http://hl7.org/fhir/StructureDefinition/Extension",
        "severity": "error",
        "expression": "extension.exists() != value.exists()"
      } ],
      "path": "StemCellTransplantation.bloodBeforeTransplant.modifierExtension",
      "requirements": "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored.  This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](http://hl7.org/fhir/R4/extensibility.html#modifierExtension).",
      "min": 0,
      "definition": "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).",
      "isModifier": true,
      "short": "Extensions that cannot be ignored even if unrecognized",
      "mapping": [ {
        "map": "N/A",
        "identity": "rim"
      } ],
      "type": [ {
        "code": "Extension"
      } ],
      "alias": [ "extensions", "user content", "modifiers" ],
      "max": "*",
      "id": "StemCellTransplantation.bloodBeforeTransplant.modifierExtension",
      "comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
      "base": {
        "max": "*",
        "min": 0,
        "path": "BackboneElement.modifierExtension"
      },
      "isModifierReason": "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them",
      "isSummary": true
    }, {
      "path": "StemCellTransplantation.bloodBeforeTransplant.type",
      "min": 1,
      "definition": "Blood type before transplant \n1 => A\n2 => B\n3 => AB\n4 => O \n-9922 => NK",
      "short": "Blood type",
      "mapping": [ {
        "map": "component.where(code = $loinc#883-9\t'ABO group [Type] in Blood').value",
        "identity": "fhir"
      } ],
      "type": [ {
        "code": "CodeableConcept"
      } ],
      "max": "1",
      "id": "StemCellTransplantation.bloodBeforeTransplant.type",
      "base": {
        "max": "1",
        "min": 1,
        "path": "StemCellTransplantation.bloodBeforeTransplant.type"
      }
    }, {
      "path": "StemCellTransplantation.bloodBeforeTransplant.rh",
      "min": 1,
      "definition": "Rh factor before transplant\n1 => +\n2 => -\n-9922 => NK ",
      "short": "Rh",
      "mapping": [ {
        "map": "component.where(code = $loinc#10331-7 'Rh [Type] in Blood').value",
        "identity": "fhir"
      } ],
      "type": [ {
        "code": "CodeableConcept"
      } ],
      "max": "1",
      "id": "StemCellTransplantation.bloodBeforeTransplant.rh",
      "base": {
        "max": "1",
        "min": 1,
        "path": "StemCellTransplantation.bloodBeforeTransplant.rh"
      }
    }, {
      "constraint": [ {
        "key": "ele-1",
        "human": "All FHIR elements must have a @value or children",
        "xpath": "@value|f:*|h:div",
        "source": "http://hl7.org/fhir/StructureDefinition/Element",
        "severity": "error",
        "expression": "hasValue() or (children().count() > id.count())"
      } ],
      "path": "StemCellTransplantation.bloodAfterTransplant",
      "min": 0,
      "definition": "Blood after transplant ",
      "short": "Blood after transplant",
      "mapping": [ {
        "map": "Observation.conformsTo('http://hl7.eu/fhir/ig/pcsp/StructureDefinition/Observation-bld-abo-rh-eu-pcsp').where(effectiveTiming.code = #after-procedure)",
        "identity": "fhir"
      } ],
      "type": [ {
        "code": "BackboneElement"
      } ],
      "max": "1",
      "id": "StemCellTransplantation.bloodAfterTransplant",
      "base": {
        "max": "1",
        "min": 0,
        "path": "StemCellTransplantation.bloodAfterTransplant"
      }
    }, {
      "path": "StemCellTransplantation.bloodAfterTransplant.id",
      "min": 0,
      "definition": "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
      "isModifier": false,
      "short": "Unique id for inter-element referencing",
      "mapping": [ {
        "map": "n/a",
        "identity": "rim"
      } ],
      "type": [ {
        "code": "http://hl7.org/fhirpath/System.String",
        "extension": [ {
          "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
          "valueUrl": "string"
        } ]
      } ],
      "representation": [ "xmlAttr" ],
      "max": "1",
      "id": "StemCellTransplantation.bloodAfterTransplant.id",
      "base": {
        "max": "1",
        "min": 0,
        "path": "Element.id"
      },
      "isSummary": false
    }, {
      "constraint": [ {
        "key": "ele-1",
        "human": "All FHIR elements must have a @value or children",
        "xpath": "@value|f:*|h:div",
        "source": "http://hl7.org/fhir/StructureDefinition/Element",
        "severity": "error",
        "expression": "hasValue() or (children().count() > id.count())"
      }, {
        "key": "ext-1",
        "human": "Must have either extensions or value[x], not both",
        "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
        "source": "http://hl7.org/fhir/StructureDefinition/Extension",
        "severity": "error",
        "expression": "extension.exists() != value.exists()"
      } ],
      "path": "StemCellTransplantation.bloodAfterTransplant.extension",
      "min": 0,
      "definition": "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
      "isModifier": false,
      "short": "Additional content defined by implementations",
      "mapping": [ {
        "map": "n/a",
        "identity": "rim"
      } ],
      "slicing": {
        "rules": "open",
        "description": "Extensions are always sliced by (at least) url",
        "discriminator": [ {
          "path": "url",
          "type": "value"
        } ]
      },
      "type": [ {
        "code": "Extension"
      } ],
      "alias": [ "extensions", "user content" ],
      "max": "*",
      "id": "StemCellTransplantation.bloodAfterTransplant.extension",
      "comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
      "base": {
        "max": "*",
        "min": 0,
        "path": "Element.extension"
      },
      "isSummary": false
    }, {
      "constraint": [ {
        "key": "ele-1",
        "human": "All FHIR elements must have a @value or children",
        "xpath": "@value|f:*|h:div",
        "source": "http://hl7.org/fhir/StructureDefinition/Element",
        "severity": "error",
        "expression": "hasValue() or (children().count() > id.count())"
      }, {
        "key": "ext-1",
        "human": "Must have either extensions or value[x], not both",
        "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
        "source": "http://hl7.org/fhir/StructureDefinition/Extension",
        "severity": "error",
        "expression": "extension.exists() != value.exists()"
      } ],
      "path": "StemCellTransplantation.bloodAfterTransplant.modifierExtension",
      "requirements": "Modifier extensions allow for extensions that *cannot* be safely ignored to be clearly distinguished from the vast majority of extensions which can be safely ignored.  This promotes interoperability by eliminating the need for implementers to prohibit the presence of extensions. For further information, see the [definition of modifier extensions](http://hl7.org/fhir/R4/extensibility.html#modifierExtension).",
      "min": 0,
      "definition": "May be used to represent additional information that is not part of the basic definition of the element and that modifies the understanding of the element in which it is contained and/or the understanding of the containing element's descendants. Usually modifier elements provide negation or qualification. To make the use of extensions safe and manageable, there is a strict set of governance applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension. Applications processing a resource are required to check for modifier extensions.\n\nModifier extensions SHALL NOT change the meaning of any elements on Resource or DomainResource (including cannot change the meaning of modifierExtension itself).",
      "isModifier": true,
      "short": "Extensions that cannot be ignored even if unrecognized",
      "mapping": [ {
        "map": "N/A",
        "identity": "rim"
      } ],
      "type": [ {
        "code": "Extension"
      } ],
      "alias": [ "extensions", "user content", "modifiers" ],
      "max": "*",
      "id": "StemCellTransplantation.bloodAfterTransplant.modifierExtension",
      "comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
      "base": {
        "max": "*",
        "min": 0,
        "path": "BackboneElement.modifierExtension"
      },
      "isModifierReason": "Modifier extensions are expected to modify the meaning or interpretation of the element that contains them",
      "isSummary": true
    }, {
      "path": "StemCellTransplantation.bloodAfterTransplant.type",
      "min": 1,
      "definition": "Blood type after transplant \n1 => A\n2 => B\n3 => AB\n4 => O \n-9922 => NK",
      "short": "Blood type",
      "mapping": [ {
        "map": "component.where(code = $loinc#883-9\t'ABO group [Type] in Blood').value",
        "identity": "fhir"
      } ],
      "type": [ {
        "code": "CodeableConcept"
      } ],
      "max": "1",
      "id": "StemCellTransplantation.bloodAfterTransplant.type",
      "base": {
        "max": "1",
        "min": 1,
        "path": "StemCellTransplantation.bloodAfterTransplant.type"
      }
    }, {
      "path": "StemCellTransplantation.bloodAfterTransplant.rh",
      "min": 1,
      "definition": "Rh factor after transplant\n1 => +\n2 => -\n-9922 => NK ",
      "short": "Rh",
      "mapping": [ {
        "map": "component.where(code = $loinc#10331-7 'Rh [Type] in Blood').value",
        "identity": "fhir"
      } ],
      "type": [ {
        "code": "CodeableConcept"
      } ],
      "max": "1",
      "id": "StemCellTransplantation.bloodAfterTransplant.rh",
      "base": {
        "max": "1",
        "min": 1,
        "path": "StemCellTransplantation.bloodAfterTransplant.rh"
      }
    }, {
      "path": "StemCellTransplantation.endOfTreatment",
      "min": 0,
      "definition": "Date of end of immunosuppressive treatment. If the date is unkown or partially missed insert the year at the best of your knowledge.",
      "short": "Date of end of immunosuppressive treatmentafter HSCT",
      "mapping": [ {
        "map": "Procedure.conformsTo('http://hl7.eu/fhir/ig/pcsp/StructureDefinition/Procedure-sct-prophylaxis-eu-pcsp').where(category = $sct#416608005 'Drug therapy' ).performedPeriod.end",
        "identity": "fhir"
      } ],
      "type": [ {
        "code": "date"
      } ],
      "max": "1",
      "id": "StemCellTransplantation.endOfTreatment",
      "base": {
        "max": "1",
        "min": 0,
        "path": "StemCellTransplantation.endOfTreatment"
      }
    } ]
  },
  "status": "active",
  "id": "5a2c8f42-c189-47b4-abee-898b77840b0d",
  "kind": "logical",
  "url": "http://hl7.eu/fhir/ig/pcsp/StructureDefinition/StemCellTransplantation",
  "version": "0.1.0",
  "differential": {
    "element": [ {
      "id": "StemCellTransplantation",
      "path": "StemCellTransplantation",
      "short": "Stem Cell Transplantation",
      "mapping": [ {
        "map": "Procedure.conformsTo('http://hl7.eu/fhir/ig/pcsp/StructureDefinition/Procedure-sct-eu-pcsp')",
        "identity": "fhir"
      } ],
      "definition": "Stem Cell Transplantation.\nMaturity Level: 2 - Ready for Review"
    }, {
      "id": "StemCellTransplantation.identifier",
      "max": "*",
      "min": 1,
      "path": "StemCellTransplantation.identifier",
      "type": [ {
        "code": "Identifier"
      } ],
      "short": "SCT Identifier",
      "mapping": [ {
        "map": ".identifier",
        "identity": "fhir"
      } ],
      "definition": "Progressive SCT number"
    }, {
      "id": "StemCellTransplantation.relatedDiagnosis",
      "max": "*",
      "min": 1,
      "path": "StemCellTransplantation.relatedDiagnosis",
      "type": [ {
        "code": "Identifier"
      } ],
      "short": "Progressive number of diagnosis",
      "mapping": [ {
        "map": ".reasonReference",
        "identity": "fhir"
      } ],
      "definition": "Progressive number of diagnosis"
    }, {
      "id": "StemCellTransplantation.relatedRelapse",
      "max": "*",
      "min": 1,
      "path": "StemCellTransplantation.relatedRelapse",
      "type": [ {
        "code": "Identifier"
      } ],
      "short": "Progressive number of relapse/progression (after FLT)",
      "mapping": [ {
        "map": ".reasonReference",
        "identity": "fhir"
      } ],
      "definition": "Progressive number of relapse/progression (after FLT)"
    }, {
      "id": "StemCellTransplantation.istitutionOfTreatment",
      "max": "1",
      "min": 0,
      "path": "StemCellTransplantation.istitutionOfTreatment",
      "type": [ {
        "code": "BackboneElement"
      } ],
      "short": "Institution of treatment",
      "mapping": [ {
        "map": "location.resolve().conformsTo(http://hl7.eu/fhir/ig/pcsp/StructureDefinition/Location-eu-pcsp)",
        "identity": "fhir"
      } ],
      "definition": "Please Identify the institution were the procedure was performed"
    }, {
      "id": "StemCellTransplantation.istitutionOfTreatment.description",
      "max": "1",
      "min": 0,
      "path": "StemCellTransplantation.istitutionOfTreatment.description",
      "type": [ {
        "code": "string"
      } ],
      "short": "Institution description",
      "mapping": [ {
        "map": "Location.description",
        "identity": "fhir"
      } ],
      "definition": "Institution description"
    }, {
      "id": "StemCellTransplantation.istitutionOfTreatment.name",
      "max": "1",
      "min": 0,
      "path": "StemCellTransplantation.istitutionOfTreatment.name",
      "type": [ {
        "code": "string"
      } ],
      "short": "Institution name",
      "mapping": [ {
        "map": "Location.name",
        "identity": "fhir"
      } ],
      "definition": "Institution name"
    }, {
      "id": "StemCellTransplantation.istitutionOfTreatment.address",
      "max": "1",
      "min": 0,
      "path": "StemCellTransplantation.istitutionOfTreatment.address",
      "type": [ {
        "code": "BackboneElement"
      } ],
      "short": "Institution address",
      "mapping": [ {
        "map": "Location.address.city",
        "identity": "fhir"
      } ],
      "definition": "Institution address"
    }, {
      "id": "StemCellTransplantation.istitutionOfTreatment.address.name",
      "max": "1",
      "min": 0,
      "path": "StemCellTransplantation.istitutionOfTreatment.address.name",
      "type": [ {
        "code": "string"
      } ],
      "short": "Institution city",
      "definition": "Institution city"
    }, {
      "id": "StemCellTransplantation.istitutionOfTreatment.address.country",
      "max": "1",
      "min": 0,
      "path": "StemCellTransplantation.istitutionOfTreatment.address.country",
      "type": [ {
        "code": "string"
      } ],
      "short": "Institution country",
      "mapping": [ {
        "map": "Location.address.country",
        "identity": "fhir"
      } ],
      "definition": "Institution country"
    }, {
      "id": "StemCellTransplantation.date",
      "max": "*",
      "min": 0,
      "path": "StemCellTransplantation.date",
      "type": [ {
        "code": "dateTime"
      } ],
      "short": "Date of transplant",
      "mapping": [ {
        "map": ".performedDateTime",
        "identity": "fhir"
      } ],
      "definition": "Date of the reinfusion of hematopoietic stem cells. If the date is unkown or partially missed insert the year at the best of your knowledge."
    }, {
      "id": "StemCellTransplantation.transplantType",
      "max": "1",
      "min": 0,
      "path": "StemCellTransplantation.transplantType",
      "type": [ {
        "code": "CodeableConcept"
      } ],
      "short": "Type of transplant",
      "mapping": [ {
        "map": ".code",
        "identity": "fhir"
      } ],
      "definition": "Indicate if the transplant was autologous or allogeneic.\n1 = Autologous\n2 = Allogeneic\n-9922 = NK"
    }, {
      "id": "StemCellTransplantation.donorType",
      "max": "1",
      "min": 0,
      "path": "StemCellTransplantation.donorType",
      "type": [ {
        "code": "CodeableConcept"
      } ],
      "short": "Type of donor",
      "mapping": [ {
        "map": "BiologicallyDerivedProduct .conformsTo('http://hl7.eu/fhir/ig/pcsp/StructureDefinition/BiologicallyDerivedProduct-sct-eu-pcsp').extension('http://hl7.eu/fhir/ig/pcsp/StructureDefinition/sct-donor-type').valueCodeableConcept",
        "identity": "fhir"
      } ],
      "definition": "Define the type of donor \nin case of allogenic transplant,\n1 = matched related\n2 = matched unrelated\n3 = mismatch related\n4 = mismatch unrelated\n5 = haplo-identical\n-9922 = NK\n\n1 = matched related ? sibling\n2 = matched related ? parent\n3 = matched related ? other (e.g. cousin)\n-9922 = NK"
    }, {
      "id": "StemCellTransplantation.cellSource",
      "max": "1",
      "min": 0,
      "path": "StemCellTransplantation.cellSource",
      "type": [ {
        "code": "CodeableConcept"
      } ],
      "short": "Source of cells",
      "mapping": [ {
        "map": "BiologicallyDerivedProduct .conformsTo('http://hl7.eu/fhir/ig/pcsp/StructureDefinition/BiologicallyDerivedProduct-sct-eu-pcsp').extension('http://hl7.eu/fhir/ig/pcsp/StructureDefinition/sct-source-type').valueCodeableConcept",
        "identity": "fhir"
      } ],
      "definition": "Indicate the source of cells\n1 = PBSC \n2 = Bone marrow\n3 = Cord\n-9922 = NK"
    }, {
      "id": "StemCellTransplantation.conditioningRegimen",
      "max": "1",
      "min": 0,
      "path": "StemCellTransplantation.conditioningRegimen",
      "type": [ {
        "code": "string"
      } ],
      "short": "Conditioning regimen: drugs used",
      "mapping": [ {
        "map": "Procedure.conformsTo('http://hl7.eu/fhir/ig/pcsp/StructureDefinition/Procedure-sct-prophylaxis-eu-pcsp').where(reasonReference.resolve().conformTo('http://hl7.eu/fhir/ig/pcsp/StructureDefinition/Procedure-sct-eu-pcsp') ).text",
        "identity": "fhir"
      } ],
      "definition": "Please list the drugs (name) and radiotherapy used or the conditioning regimen.  These drugs contribute to the calculation of cumulative doses received by the patient reported in the chemotherapy section.  Here it is requested only the names of the drugs and if possible the dosage used (only for possible information in the future).\nNo calculations are made on these data."
    }, {
      "id": "StemCellTransplantation.gvhd",
      "max": "1",
      "min": 0,
      "path": "StemCellTransplantation.gvhd",
      "type": [ {
        "code": "BackboneElement"
      } ],
      "short": "Graft Versus Host Disease",
      "mapping": [ {
        "map": "Condition.conformsTo('http://hl7.eu/fhir/ig/pcsp/StructureDefinition/Condition-gvdh-eu-pcsp')",
        "identity": "fhir"
      } ],
      "definition": "Graft Versus Host Disease"
    }, {
      "id": "StemCellTransplantation.gvhd.prophylaxis",
      "max": "1",
      "min": 0,
      "path": "StemCellTransplantation.gvhd.prophylaxis",
      "type": [ {
        "code": "CodeableConcept"
      } ],
      "short": "GVHD prophylaxis",
      "mapping": [ {
        "map": "Procedure.conformsTo('http://hl7.eu/fhir/ig/pcsp/StructureDefinition/Procedure-sct-prophylaxis-eu-pcsp').where(code = $sct#868254008 'GVHD (graft versus host disease) prophylaxis').exists()",
        "identity": "fhir"
      } ],
      "definition": "State if any GVHD prophylaxis was given. Details on the drug names used for GVHD prophylaxis should be listed in the chemotherapy section under 'immunotherapy').\n1 => Yes\n2 => No\n-9922 => NK   "
    }, {
      "id": "StemCellTransplantation.gvhd.acute",
      "max": "1",
      "min": 0,
      "path": "StemCellTransplantation.gvhd.acute",
      "type": [ {
        "code": "BackboneElement"
      } ],
      "short": "GVHD Acute",
      "mapping": [ {
        "map": ".where(code = http://snomed.info/sct#402355000 'Acute graft-versus-host disease')",
        "identity": "fhir"
      } ],
      "definition": "GVHD Acute "
    }, {
      "id": "StemCellTransplantation.gvhd.acute.status",
      "max": "1",
      "min": 1,
      "path": "StemCellTransplantation.gvhd.acute.status",
      "type": [ {
        "code": "CodeableConcept"
      } ],
      "short": "GVHD Acutestatus",
      "mapping": [ {
        "map": ".where(code = http://snomed.info/sct#402355000 'Acute graft-versus-host disease').exists()",
        "identity": "fhir"
      } ],
      "definition": "Please State if acute GVHD occurred\n1 => Yes\n2 => No\n-9922 => NK "
    }, {
      "id": "StemCellTransplantation.gvhd.acute.grade",
      "max": "1",
      "min": 1,
      "path": "StemCellTransplantation.gvhd.acute.grade",
      "type": [ {
        "code": "CodeableConcept"
      } ],
      "short": "Grade",
      "mapping": [ {
        "map": ".stage.summary",
        "identity": "fhir"
      } ],
      "definition": "If yes, state the maximum grade of acute GVHD.\n\n1 => 1\n2 => 2\n3 => 3\n4 => 4\n-9922 => NK "
    }, {
      "id": "StemCellTransplantation.gvhd.acute.startDate",
      "max": "1",
      "min": 0,
      "path": "StemCellTransplantation.gvhd.acute.startDate",
      "type": [ {
        "code": "date"
      } ],
      "short": "Start date",
      "mapping": [ {
        "map": ".onsetDateTime",
        "identity": "fhir"
      } ],
      "definition": "Define the starting date of GVHD. If the date is unkown or partially missed insert the year at the best of your knowledge."
    }, {
      "id": "StemCellTransplantation.gvhd.acute.endDate",
      "max": "1",
      "min": 0,
      "path": "StemCellTransplantation.gvhd.acute.endDate",
      "type": [ {
        "code": "date"
      } ],
      "short": "End date",
      "mapping": [ {
        "map": ".abatementDateTime",
        "identity": "fhir"
      } ],
      "definition": "Define the ending date of GVHD. If the date is unkown or partially missed insert the year at the best of your knowledge."
    }, {
      "id": "StemCellTransplantation.gvhd.chronic",
      "max": "1",
      "min": 0,
      "path": "StemCellTransplantation.gvhd.chronic",
      "type": [ {
        "code": "BackboneElement"
      } ],
      "short": "GVHD Chronic",
      "mapping": [ {
        "map": ".where(code = http://snomed.info/sct#402356004 'Chronic graft-versus-host disease')",
        "identity": "fhir"
      } ],
      "definition": "GVHD Chronic "
    }, {
      "id": "StemCellTransplantation.gvhd.chronic.status",
      "max": "1",
      "min": 1,
      "path": "StemCellTransplantation.gvhd.chronic.status",
      "type": [ {
        "code": "CodeableConcept"
      } ],
      "short": "GVHD Chronicstatus",
      "mapping": [ {
        "map": ".where(code = http://snomed.info/sct#402356004 'Chronic graft-versus-host disease').exists()",
        "identity": "fhir"
      } ],
      "definition": "Please State if chronic GVHD occurred\n1 => Yes\n2 => No\n-9922 => NK "
    }, {
      "id": "StemCellTransplantation.gvhd.chronic.grade",
      "max": "1",
      "min": 1,
      "path": "StemCellTransplantation.gvhd.chronic.grade",
      "type": [ {
        "code": "CodeableConcept"
      } ],
      "short": "Grade",
      "mapping": [ {
        "map": ".stage.summary",
        "identity": "fhir"
      } ],
      "definition": " If yes, state the maximum grade of chronic GVHD\n1 => Limited\n2 => Extensive\n-9922 => NK"
    }, {
      "id": "StemCellTransplantation.gvhd.chronic.startDate",
      "max": "1",
      "min": 0,
      "path": "StemCellTransplantation.gvhd.chronic.startDate",
      "type": [ {
        "code": "date"
      } ],
      "short": "Start date",
      "mapping": [ {
        "map": ".onsetDateTime",
        "identity": "fhir"
      } ],
      "definition": "Please Define the starting date of GVHD. If the date is unkown or partially missed insert the year at the best of your knowledge."
    }, {
      "id": "StemCellTransplantation.gvhd.chronic.endDate",
      "max": "1",
      "min": 0,
      "path": "StemCellTransplantation.gvhd.chronic.endDate",
      "type": [ {
        "code": "date"
      } ],
      "short": "End date",
      "mapping": [ {
        "map": ".abatementDateTime",
        "identity": "fhir"
      } ],
      "definition": "Please Define the ending date of GVHD. If the date is unkown or partially missed insert the year at the best of your knowledge."
    }, {
      "id": "StemCellTransplantation.gvhd.organAffected",
      "max": "*",
      "min": 0,
      "path": "StemCellTransplantation.gvhd.organAffected",
      "type": [ {
        "code": "string"
      } ],
      "short": "Organs affected",
      "mapping": [ {
        "map": ".bodySite",
        "identity": "fhir"
      } ],
      "definition": "Please List organs affected by GVHD"
    }, {
      "id": "StemCellTransplantation.bloodBeforeTransplant",
      "max": "1",
      "min": 0,
      "path": "StemCellTransplantation.bloodBeforeTransplant",
      "type": [ {
        "code": "BackboneElement"
      } ],
      "short": "Blood before transplant",
      "mapping": [ {
        "map": "Observation.conformsTo('http://hl7.eu/fhir/ig/pcsp/StructureDefinition/Observation-bld-abo-rh-eu-pcsp').where(effectiveTiming.code = #before-procedure)",
        "identity": "fhir"
      } ],
      "definition": "Blood before transplant "
    }, {
      "id": "StemCellTransplantation.bloodBeforeTransplant.type",
      "max": "1",
      "min": 1,
      "path": "StemCellTransplantation.bloodBeforeTransplant.type",
      "type": [ {
        "code": "CodeableConcept"
      } ],
      "short": "Blood type",
      "mapping": [ {
        "map": "component.where(code = $loinc#883-9\t'ABO group [Type] in Blood').value",
        "identity": "fhir"
      } ],
      "definition": "Blood type before transplant \n1 => A\n2 => B\n3 => AB\n4 => O \n-9922 => NK"
    }, {
      "id": "StemCellTransplantation.bloodBeforeTransplant.rh",
      "max": "1",
      "min": 1,
      "path": "StemCellTransplantation.bloodBeforeTransplant.rh",
      "type": [ {
        "code": "CodeableConcept"
      } ],
      "short": "Rh",
      "mapping": [ {
        "map": "component.where(code = $loinc#10331-7 'Rh [Type] in Blood').value",
        "identity": "fhir"
      } ],
      "definition": "Rh factor before transplant\n1 => +\n2 => -\n-9922 => NK "
    }, {
      "id": "StemCellTransplantation.bloodAfterTransplant",
      "max": "1",
      "min": 0,
      "path": "StemCellTransplantation.bloodAfterTransplant",
      "type": [ {
        "code": "BackboneElement"
      } ],
      "short": "Blood after transplant",
      "mapping": [ {
        "map": "Observation.conformsTo('http://hl7.eu/fhir/ig/pcsp/StructureDefinition/Observation-bld-abo-rh-eu-pcsp').where(effectiveTiming.code = #after-procedure)",
        "identity": "fhir"
      } ],
      "definition": "Blood after transplant "
    }, {
      "id": "StemCellTransplantation.bloodAfterTransplant.type",
      "max": "1",
      "min": 1,
      "path": "StemCellTransplantation.bloodAfterTransplant.type",
      "type": [ {
        "code": "CodeableConcept"
      } ],
      "short": "Blood type",
      "mapping": [ {
        "map": "component.where(code = $loinc#883-9\t'ABO group [Type] in Blood').value",
        "identity": "fhir"
      } ],
      "definition": "Blood type after transplant \n1 => A\n2 => B\n3 => AB\n4 => O \n-9922 => NK"
    }, {
      "id": "StemCellTransplantation.bloodAfterTransplant.rh",
      "max": "1",
      "min": 1,
      "path": "StemCellTransplantation.bloodAfterTransplant.rh",
      "type": [ {
        "code": "CodeableConcept"
      } ],
      "short": "Rh",
      "mapping": [ {
        "map": "component.where(code = $loinc#10331-7 'Rh [Type] in Blood').value",
        "identity": "fhir"
      } ],
      "definition": "Rh factor after transplant\n1 => +\n2 => -\n-9922 => NK "
    }, {
      "id": "StemCellTransplantation.endOfTreatment",
      "max": "1",
      "min": 0,
      "path": "StemCellTransplantation.endOfTreatment",
      "type": [ {
        "code": "date"
      } ],
      "short": "Date of end of immunosuppressive treatmentafter HSCT",
      "mapping": [ {
        "map": "Procedure.conformsTo('http://hl7.eu/fhir/ig/pcsp/StructureDefinition/Procedure-sct-prophylaxis-eu-pcsp').where(category = $sct#416608005 'Drug therapy' ).performedPeriod.end",
        "identity": "fhir"
      } ],
      "definition": "Date of end of immunosuppressive treatment. If the date is unkown or partially missed insert the year at the best of your knowledge."
    } ]
  },
  "contact": [ {
    "name": "PanCareSurPass Project",
    "telecom": [ {
      "value": "https://www.pancaresurpass.eu/",
      "system": "url"
    } ]
  }, {
    "name": "PanCareSurPass Project",
    "telecom": [ {
      "value": "https://www.pancaresurpass.eu/",
      "system": "url"
    } ]
  } ],
  "baseDefinition": "http://hl7.org/fhir/StructureDefinition/Base"
}