description: In Situ Hybridization report
package_name: de.medizininformatikinitiative.kerndatensatz.mtb
derivation: constraint
name: MII_PR_MTB_INSITUHYBRIDIZATION_HER2
type: Observation
elements:
  category:
    index: 0
    slicing:
      slices:
        biomarker-category:
          match: {}
          schema:
            index: 0
            elements:
              coding:
                elements:
                  code:
                    pattern: {type: Code, value: inSituHybridization}
                    index: 1
  code:
    elements:
      coding:
        pattern:
          type: Coding
          value: {code: 18474-7, system: 'http://loinc.org', display: 'ERBB2 gene duplication [Presence] in Tissue by FISH'}
        index: 2
  value:
    choices: []
    index: 4
    slicing:
      rules: open
      ordered: false
      discriminator:
      - {path: $this, type: type}
      min: null
      slices:
        valueCodeableConcept:
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          schema:
            choices: [valueCodeableConcept]
            index: 6
          min: 0
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    slicing:
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  value[x]:
    elements:
      coding:
        elements:
          system:
            pattern: {type: Uri, value: 'http://loinc.org'}
            index: 8
          code:
            binding: {strength: required, valueSet: 'http://loinc.org/vs/LL360-9-9'}
            index: 9
  component:
    index: 10
    slicing:
      slices:
        gene-studied:
          match: {}
          schema:
            index: 10
            elements:
              value:
                pattern:
                  type: CodeableConcept
                  value:
                    coding:
                    - {code: 'HGNC:2064', system: 'http://www.genenames.org/geneId', display: ERBB2}
                choices: [valueCodeableConcept]
                index: 12
                slicing:
                  slices:
                    valueCodeableConcept:
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                      schema:
                        pattern:
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                type: CodeableConcept
                pattern:
                  type: CodeableConcept
                  value:
                    coding:
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                slicing:
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                    valueCodeableConcept:
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                      schema:
                        type: CodeableConcept
                        pattern:
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package_version: 2025.0.0-ballot-alpha.1
class: profile
kind: resource
url: https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-pr-mtb-insituhybridization-her2
base: https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-pr-mtb-molekularer-biomarker
version: 2024.0.0-ballot