description: Beschreibt die Gesamtploidie des Tumors. Die Ploidie ist ein Indikator für die Tumorproliferation und die Tumoraggressivität.
package_name: de.medizininformatikinitiative.kerndatensatz.mtb
derivation: constraint
name: MII_PR_MTB_Ploidie
type: Observation
elements:
  code:
    short: Ploidie
    _short:
      extension:
      - url: http://hl7.org/fhir/StructureDefinition/translation
        extension:
        - {url: lang, valueCode: de-DE}
        - {url: content, valueString: Ploidie}
      - url: http://hl7.org/fhir/StructureDefinition/translation
        extension:
        - {url: lang, valueCode: en}
        - {url: content, valueString: Ploidy}
    _definition:
      extension:
      - url: http://hl7.org/fhir/StructureDefinition/translation
        extension:
        - {url: lang, valueCode: de-DE}
        - {url: content, valueString: Ploidie der Tumorprobe}
      - url: http://hl7.org/fhir/StructureDefinition/translation
        extension:
        - {url: lang, valueCode: en}
        - {url: content, valueString: Ploidy of the tumor specimen}
    index: 0
    elements:
      coding:
        index: 1
        slicing:
          rules: open
          ordered: false
          description: Slices for code.coding
          discriminator:
          - {path: $this, type: pattern}
          min: 1
          slices:
            NCIT:
              match: {code: C18303, system: 'https://nih-ncpi.github.io/ncpi-fhir-ig/CodeSystem-ncit.html', display: DNA Ploidy Analysis}
              schema:
                mustSupport: true
                pattern:
                  type: Coding
                  value: {code: C18303, system: 'https://nih-ncpi.github.io/ncpi-fhir-ig/CodeSystem-ncit.html', display: DNA Ploidy Analysis}
                _required: true
                index: 2
              min: 1
              max: 1
    required: [coding]
  value:
    mustSupport: true
    choices: []
    index: 4
    slicing:
      rules: open
      ordered: false
      discriminator:
      - {path: $this, type: type}
      min: null
      slices:
        valueQuantity:
          match: {}
          schema:
            mustSupport: true
            choices: [valueQuantity]
            index: 6
          min: 0
          max: 1
  valueQuantity:
    type: Quantity
    mustSupport: true
    choiceOf: value
    index: 7
    slicing:
      slices:
        valueQuantity:
          match: {}
          schema: {type: Quantity, mustSupport: true, choiceOf: value, index: 7}
          min: 0
          max: 1
  interpretation:
    binding: {strength: required, valueSet: 'http://hl7.org/fhir/uv/genomics-reporting/ValueSet/high-low-codes-vs'}
    mustSupport: true
    index: 8
package_version: 2026.0.1
class: profile
kind: resource
url: https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-pr-mtb-ploidie
base: https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-pr-mtb-molekularer-biomarker
version: 2026.0.1