description: Dieses Profil beschreibt die Gesamtzahl der in der DNA von Krebszellen gefundenen Mutationen.
package_name: de.medizininformatikinitiative.kerndatensatz.molgen
derivation: constraint
name: MII_PR_MolGen_Mutationslast
type: Observation
elements:
  status:
    short: Status
    _short:
      extension:
      - url: http://hl7.org/fhir/StructureDefinition/translation
        extension:
        - {url: lang, valueCode: de-DE}
        - {url: content, valueString: Status}
    _definition:
      extension:
      - url: http://hl7.org/fhir/StructureDefinition/translation
        extension:
        - {url: lang, valueCode: de-DE}
        - {url: content, valueString: Status der Beobachtung}
    mustSupport: true
    index: 0
  code:
    _definition:
      extension:
      - url: http://hl7.org/fhir/StructureDefinition/translation
        extension:
        - {url: lang, valueCode: de-DE}
        - {url: content, valueString: Code zur Identifizierung der Mutationslast}
    index: 1
  subject: {index: 2}
  value:
    short: Ergebniswert
    _definition:
      extension:
      - url: http://hl7.org/fhir/StructureDefinition/translation
        extension:
        - {url: lang, valueCode: de-DE}
        - {url: content, valueString: Der numerische Wert der Mutationslast in Mutationen pro Megabase}
    mustSupport: true
    choices: []
    _short:
      extension:
      - url: http://hl7.org/fhir/StructureDefinition/translation
        extension:
        - {url: lang, valueCode: de-DE}
        - {url: content, valueString: Ergebniswert}
    index: 4
    slicing:
      rules: open
      ordered: false
      discriminator:
      - {path: $this, type: type}
      min: null
      slices:
        valueQuantity:
          match: {}
          schema:
            choices: [valueQuantity]
            index: 6
          min: 0
          max: 1
  valueQuantity:
    type: Quantity
    choiceOf: value
    index: 7
    slicing:
      slices:
        valueQuantity:
          match: {}
          schema: {type: Quantity, choiceOf: value, index: 7}
          min: 0
          max: 1
  specimen:
    short: Probe
    _short:
      extension:
      - url: http://hl7.org/fhir/StructureDefinition/translation
        extension:
        - {url: lang, valueCode: de-DE}
        - {url: content, valueString: Probe}
    _definition:
      extension:
      - url: http://hl7.org/fhir/StructureDefinition/translation
        extension:
        - {url: lang, valueCode: de-DE}
        - {url: content, valueString: Die untersuchte Tumorprobe}
    mustSupport: true
    index: 8
package_version: 2026.0.2
class: profile
kind: resource
url: https://www.medizininformatik-initiative.de/fhir/ext/modul-molgen/StructureDefinition/mutationslast
base: https://www.medizininformatik-initiative.de/fhir/ext/modul-molgen/StructureDefinition/mii-pr-molgen-molekularer-biomarker
version: 2026.0.2
required: [subject]