PackagesCanonicalsLogsProblems
    Packages
    hl7.fhir.uv.ebm@1.0.0-ballot2
    https://fevir.net/resources/Evidence/179635
{
  "description": "Dropout due to stopping intervention 18/33 with Lofexidine vs. 12/35 with Placebo in opioid detoxification trial",
  "_filename": "example/Evidence-179635.json",
  "package_name": "hl7.fhir.uv.ebm",
  "statistic": [ {
    "quantity": {
      "value": 1.59
    },
    "sampleSize": {
      "numberOfParticipants": 68
    },
    "description": "18/33 (54.5%) with Lofexidine vs. 12/35 (34.3%) with Placebo (relative risk 1.59, p < 0.01)",
    "statisticType": {
      "coding": [ {
        "code": "STATO:0000245",
        "system": "https://fevir.net/sevco",
        "display": "Risk Ratio"
      } ]
    },
    "numberAffected": 30,
    "attributeEstimate": [ {
      "type": {
        "coding": [ {
          "code": "STATO:0000700",
          "system": "https://fevir.net/sevco",
          "display": "p-value"
        } ]
      },
      "quantity": {
        "value": 0.01,
        "comparator": "<"
      },
      "description": "p < 0.01"
    } ]
  } ],
  "date": null,
  "meta": {
    "profile": [ "http://hl7.org/fhir/uv/ebm/StructureDefinition/comparative-participant-flow-evidence" ],
    "versionId": "7",
    "lastUpdated": "2024-12-13T21:07:33.593Z"
  },
  "publisher": "Computable Publishing LLC",
  "name": "ComparativeParticipantFlowEvidence_Dropout_due_to_stopping_intervention_Lofexidine_vs_Placebo_in_opioid_detoxification_trial",
  "useContext": [ {
    "code": {
      "code": "evidence-communication",
      "system": "https://fevir.net/resources/CodeSystem/179423",
      "display": "Evidence Communication"
    },
    "valueCodeableConcept": {
      "coding": [ {
        "code": "ComparativeParticipantFlowEvidence",
        "system": "https://fevir.net/resources/CodeSystem/179423",
        "display": "ComparativeParticipantFlowEvidence"
      } ]
    }
  } ],
  "copyright": "https://creativecommons.org/licenses/by-nc-sa/4.0/",
  "type": null,
  "experimental": null,
  "resourceType": "Evidence",
  "variableDefinition": [ {
    "description": "Participants in the opioid detoxification trial",
    "variableRole": "population"
  }, {
    "description": "GroupAssignment: Lofexidine vs. Placebo",
    "variableRole": "exposure",
    "comparatorCategory": "false"
  }, {
    "observed": {
      "type": "EvidenceVariable",
      "display": "PartiicipantFlowMeasure: Dropout due to stopping intervention",
      "reference": "EvidenceVariable/179636"
    },
    "description": "Dropout due to stopping intervention",
    "variableRole": "outcome"
  } ],
  "title": "ComparativeParticipantFlowEvidence: Dropout due to stopping intervention Lofexidine vs. Placebo in opioid detoxification trial",
  "package_version": "1.0.0-ballot2",
  "author": [ {
    "name": "Brian S. Alper"
  } ],
  "extension": [ {
    "url": "http://hl7.org/fhir/uv/ebm/StructureDefinition/relates-to",
    "extension": [ {
      "url": "type",
      "valueCode": "cite-as"
    }, {
      "url": "targetMarkdown",
      "valueMarkdown": "ComparativeParticipantFlowEvidence: Dropout due to stopping intervention Lofexidine vs. Placebo in opioid detoxification trial [Database Entry: FHIR Evidence Resource]. Contributors: Brian S. Alper [Authors/Creators]. In: Fast Evidence Interoperability Resources (FEvIR) Platform, FOI 179635. Revised 2024-05-16. Available at: https://fevir.net/resources/Evidence/179635. Computable resource at: https://fevir.net/resources/Evidence/179635#json."
    } ]
  }, {
    "url": "http://hl7.org/fhir/uv/ebm/StructureDefinition/relates-to",
    "extension": [ {
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      "valueCode": "derived-from"
    }, {
      "url": "targetReference",
      "valueReference": {
        "type": "Citation",
        "display": "18508207 A Phase 3 placebo-controlled, double-blind, multi-site trial of the alpha-2-adrenergic agonist, lofexidine, for opioid withdrawal",
        "reference": "Citation/179637"
      }
    } ]
  } ],
  "status": "active",
  "id": "22ea3237-2e94-4f6c-9a8a-634dcea68771",
  "kind": null,
  "url": "https://fevir.net/resources/Evidence/179635",
  "identifier": [ {
    "type": {
      "text": "FEvIR Object Identifier",
      "coding": [ {
        "code": "ACSN",
        "system": "http://terminology.hl7.org/CodeSystem/v2-0203",
        "display": "Accession ID"
      } ]
    },
    "value": "https://fevir.net/FOI/179635",
    "system": "urn:ietf:rfc:3986",
    "assigner": {
      "display": "Computable Publishing LLC"
    }
  } ],
  "version": null,
  "contact": [ {
    "telecom": [ {
      "value": "support@computablepublishing.com",
      "system": "email"
    } ]
  } ]
}