description: RNA Seq
package_name: rs/de.medizininformatikinitiative.kerndatensatz.mtb
derivation: constraint
name: MII_PR_MTB_RNA_Seq
type: Observation
elements:
  meta:
    mustSupport: true
    index: 0
    elements:
      profile: {mustSupport: true, index: 1}
  focus:
    type: Reference
    mustSupport: true
    refers: ['https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-pr-mtb-diagnose-primaertumor', 'https://www.medizininformatik-initiative.de/fhir/ext/modul-onko/StructureDefinition/mii-pr-onko-diagnose-primaertumor']
    index: 2
  value:
    choices: []
    index: 4
  component:
    short: Gen
    index: 5
    slicing:
      slices:
        gene-studied:
          match: {}
          schema: {short: Gen, index: 5}
        variation-code:
          match: {}
          schema: {short: Entrez ID & Ensemble ID, array: true, max: 2, index: 6}
          max: 2
        transcript-id:
          match: {}
          schema:
            short: Transcript ID
            mustSupport: true
            index: 7
            elements:
              value:
                choices: [valueCodeableConcept]
                index: 9
              valueCodeableConcept: {type: CodeableConcept, choiceOf: value, index: 10}
        transcripts-per-million:
          match: {}
          schema:
            short: Transcripts per million
            mustSupport: true
            index: 11
            elements:
              value:
                choices: [valueRatio]
                index: 13
              valueRatio: {type: Ratio, choiceOf: value, index: 14}
              value[x]:
                elements:
                  denominator:
                    elements:
                      value:
                        pattern: {type: decimal, value: 1000000}
                        type: decimal
                        index: 15
        tissue-corrected-expression:
          match: {}
          schema:
            short: Tissue corrected expression
            mustSupport: true
            index: 16
            elements:
              value:
                choices: [valueBoolean]
                index: 18
              valueBoolean: {type: boolean, choiceOf: value, index: 19}
        raw-counts:
          match: {}
          schema:
            short: Raw counts
            mustSupport: true
            index: 20
            elements:
              value:
                choices: [valueQuantity]
                index: 22
              valueQuantity: {type: Quantity, choiceOf: value, index: 23}
        library-size:
          match: {}
          schema:
            short: Library size
            mustSupport: true
            index: 24
            elements:
              value:
                choices: [valueQuantity]
                index: 26
              valueQuantity: {type: Quantity, choiceOf: value, index: 27}
        cohort-ranking:
          match: {}
          schema:
            short: Cohort ranking
            mustSupport: true
            index: 28
            elements:
              value:
                choices: [valueQuantity]
                index: 30
              valueQuantity: {type: Quantity, choiceOf: value, index: 31}
package_version: 2025.0.0-ballot
class: profile
kind: resource
url: https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-pr-mtb-rna-seq
base: https://www.medizininformatik-initiative.de/fhir/ext/modul-molgen/StructureDefinition/variante
version: 2024.0.0-ballot