description: Immunhistrchemistry report
package_name: rs/de.medizininformatikinitiative.kerndatensatz.mtb
derivation: constraint
name: MII_PR_MTB_IMMUNOHISTOCHEMISTRY_HER2
type: Observation
elements:
  code:
    elements:
      coding:
        pattern:
          type: Coding
          value: {code: 18474-7, system: 'http://loinc.org', display: 'HER2 Ag [Presence] in Tissue by Immune stain'}
        type: Coding
        index: 0
  value:
    choices: [valueCodeableConcept]
    index: 2
    slicing:
      slices:
        valueCodeableConcept:
          match: {}
          schema:
            choices: [valueCodeableConcept]
            index: 2
  valueCodeableConcept:
    type: CodeableConcept
    choiceOf: value
    index: 3
    slicing:
      slices:
        valueCodeableConcept:
          match: {}
          schema: {type: CodeableConcept, choiceOf: value, index: 3}
  value[x]:
    elements:
      coding:
        short: 0|1+|2+|3+|Indeterminate
        index: 4
        elements:
          system:
            pattern: {type: uri, value: 'http://loinc.org'}
            type: uri
            index: 5
          code:
            binding: {strength: required, valueSet: 'http://loinc.org/vs/LL4396-9'}
            index: 6
  component:
    index: 7
    slicing:
      slices:
        gene-studied:
          match: {}
          schema:
            index: 7
            elements:
              value:
                pattern:
                  type: CodeableConcept
                  value:
                    coding:
                    - {code: 'HGNC:2064', system: 'http://www.genenames.org/geneId', display: ERBB2}
                choices: [valueCodeableConcept]
                type: CodeableConcept
                index: 9
                slicing:
                  slices:
                    valueCodeableConcept:
                      match: {}
                      schema:
                        pattern:
                          type: CodeableConcept
                          value:
                            coding:
                            - {code: 'HGNC:2064', system: 'http://www.genenames.org/geneId', display: ERBB2}
                        choices: [valueCodeableConcept]
                        type: CodeableConcept
                        index: 9
              valueCodeableConcept:
                type: CodeableConcept
                pattern:
                  type: CodeableConcept
                  value:
                    coding:
                    - {code: 'HGNC:2064', system: 'http://www.genenames.org/geneId', display: ERBB2}
                choiceOf: value
                index: 10
                slicing:
                  slices:
                    valueCodeableConcept:
                      match: {}
                      schema:
                        type: CodeableConcept
                        pattern:
                          type: CodeableConcept
                          value:
                            coding:
                            - {code: 'HGNC:2064', system: 'http://www.genenames.org/geneId', display: ERBB2}
                        choiceOf: value
                        index: 10
        biomarker-category:
          match: {}
          schema:
            index: 11
            elements:
              value[x]:
                elements:
                  coding:
                    pattern:
                      type: Coding
                      value: {code: immuneStain}
                    type: Coding
                    index: 12
package_version: 2025.0.0-ballot
class: profile
kind: resource
url: https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-pr-mtb-immunohistochemistry-her2
base: https://www.medizininformatik-initiative.de/fhir/ext/modul-mtb/StructureDefinition/mii-pr-mtb-immunohistochemistry
version: 2024.0.0-ballot