PackagesCanonicalsLogsProblems
    Packages
    hl7.fhir.uv.xver-r4b.r4@0.1.0
    http://hl7.org/fhir/4.3/StructureDefinition/extension-Evidence.statistic
{
  "description": "R4B: `Evidence.statistic` (new:BackboneElement)",
  "_filename": "StructureDefinition-ext-R4B-Evidence.statistic.json",
  "package_name": "hl7.fhir.uv.xver-r4b.r4",
  "date": "2026-03-17T21:02:03.8104715+00:00",
  "derivation": "constraint",
  "publisher": "FHIR Infrastructure",
  "fhirVersion": "4.0.1",
  "jurisdiction": [ {
    "coding": [ {
      "code": "001",
      "system": "http://unstats.un.org/unsd/methods/m49/m49.htm",
      "display": "World"
    } ]
  } ],
  "purpose": "This extension is part of the cross-version definitions generated to enable use of the\r\nelement `Evidence.statistic` as defined in FHIR R4B\r\nin FHIR R4.\r\n\r\nThe source element is defined as:\r\n`Evidence.statistic` 0..* `BackboneElement`\r\n\r\nFollowing are the generation technical comments:\r\nElement `Evidence.statistic` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
  "name": "ExtensionEvidence_Statistic",
  "mapping": [ {
    "uri": "http://hl7.org/v3",
    "name": "RIM Mapping",
    "identity": "rim"
  } ],
  "abstract": false,
  "type": "Extension",
  "experimental": "false",
  "resourceType": "StructureDefinition",
  "title": "R4B: Values and parameters for a single statistic (new)",
  "package_version": "0.1.0",
  "extension": [ {
    "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-wg",
    "valueCode": "fhir"
  }, {
    "url": "http://hl7.org/fhir/StructureDefinition/package-source",
    "extension": [ {
      "url": "packageId",
      "valueId": "hl7.fhir.uv.xver-r4b.r4"
    }, {
      "url": "version",
      "valueString": "0.1.0"
    }, {
      "url": "uri",
      "valueUri": "http://hl7.org/fhir/uv/xver/ImplementationGuide/hl7.fhir.uv.xver-r4b.r4"
    } ]
  }, {
    "url": "http://hl7.org/fhir/StructureDefinition/version-specific-use",
    "extension": [ {
      "url": "startFhirVersion",
      "valueCode": "4.0"
    }, {
      "url": "endFhirVersion",
      "valueCode": "4.0"
    } ]
  }, {
    "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fmm",
    "valueInteger": 0,
    "_valueInteger": {
      "extension": [ {
        "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom",
        "valueCanonical": "http://hl7.org/fhir/uv/xver/ImplementationGuide/hl7.fhir.uv.xver-r4b.r4"
      } ]
    }
  }, {
    "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status",
    "valueCode": "trial-use",
    "_valueCode": {
      "extension": [ {
        "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-conformance-derivedFrom",
        "valueCanonical": "http://hl7.org/fhir/uv/xver/ImplementationGuide/hl7.fhir.uv.xver-r4b.r4"
      } ]
    }
  } ],
  "snapshot": {
    "element": [ {
      "constraint": [ {
        "key": "ele-1",
        "human": "All FHIR elements must have a @value or children",
        "xpath": "@value|f:*|h:div",
        "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1",
        "severity": "error",
        "expression": "hasValue() or (children().count() > id.count())"
      }, {
        "key": "ext-1",
        "human": "Must have either extensions or value[x], not both",
        "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), 'value')])",
        "source": "http://hl7.org/fhir/StructureDefinition/Extension|4.0.1",
        "severity": "error",
        "expression": "extension.exists() != value.exists()"
      } ],
      "path": "Extension",
      "min": 0,
      "definition": "R4B: `Evidence.statistic` (new:BackboneElement)",
      "isModifier": false,
      "short": "R4B: Values and parameters for a single statistic (new)",
      "max": "*",
      "id": "Extension",
      "condition": [ "ele-1" ],
      "comment": "Element `Evidence.statistic` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
      "base": {
        "max": "*",
        "min": 0,
        "path": "Extension"
      }
    }, {
      "path": "Extension.id",
      "min": 0,
      "definition": "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
      "isModifier": false,
      "short": "Unique id for inter-element referencing",
      "mapping": [ {
        "map": "n/a",
        "identity": "rim"
      } ],
      "type": [ {
        "code": "http://hl7.org/fhirpath/System.String",
        "extension": [ {
          "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
          "valueUrl": "string"
        } ]
      } ],
      "representation": [ "xmlAttr" ],
      "max": "1",
      "id": "Extension.id",
      "base": {
        "max": "1",
        "min": 0,
        "path": "Element.id"
      },
      "isSummary": false
    }, {
      "constraint": [ {
        "key": "ele-1",
        "human": "All FHIR elements must have a @value or children",
        "xpath": "@value|f:*|h:div",
        "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1",
        "severity": "error",
        "expression": "hasValue() or (children().count() > id.count())"
      }, {
        "key": "ext-1",
        "human": "Must have either extensions or value[x], not both",
        "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
        "source": "http://hl7.org/fhir/StructureDefinition/Extension|4.0.1",
        "severity": "error",
        "expression": "extension.exists() != value.exists()"
      } ],
      "path": "Extension.extension",
      "min": 0,
      "definition": "An Extension",
      "isModifier": false,
      "short": "Extension",
      "slicing": {
        "rules": "open",
        "ordered": false,
        "description": "Extensions are always sliced by (at least) url",
        "discriminator": [ {
          "path": "url",
          "type": "value"
        } ]
      },
      "type": [ {
        "code": "Extension"
      } ],
      "max": "*",
      "id": "Extension.extension",
      "base": {
        "max": "*",
        "min": 0,
        "path": "Element.extension"
      },
      "isSummary": false
    }, {
      "constraint": [ {
        "key": "ele-1",
        "human": "All FHIR elements must have a @value or children",
        "xpath": "@value|f:*|h:div",
        "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1",
        "severity": "error",
        "expression": "hasValue() or (children().count() > id.count())"
      }, {
        "key": "ext-1",
        "human": "Must have either extensions or value[x], not both",
        "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
        "source": "http://hl7.org/fhir/StructureDefinition/Extension|4.0.1",
        "severity": "error",
        "expression": "extension.exists() != value.exists()"
      } ],
      "path": "Extension.extension",
      "requirements": "Element `Evidence.statistic.description` is part of an existing definition because parent element `Evidence.statistic` requires a cross-version extension.\nElement `Evidence.statistic.description` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.description` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
      "min": 0,
      "definition": "R4B: `Evidence.statistic.description` (new:string)",
      "isModifier": false,
      "short": "R4B: Description of content (new)",
      "type": [ {
        "code": "Extension"
      } ],
      "sliceName": "description",
      "max": "1",
      "id": "Extension.extension:description",
      "comment": "Element `Evidence.statistic.description` is part of an existing definition because parent element `Evidence.statistic` requires a cross-version extension.\nElement `Evidence.statistic.description` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.description` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
      "base": {
        "max": "*",
        "min": 0,
        "path": "Element.extension"
      },
      "isSummary": false
    }, {
      "path": "Extension.extension.id",
      "min": 0,
      "definition": "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
      "isModifier": false,
      "short": "Unique id for inter-element referencing",
      "mapping": [ {
        "map": "n/a",
        "identity": "rim"
      } ],
      "type": [ {
        "code": "http://hl7.org/fhirpath/System.String",
        "extension": [ {
          "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
          "valueUrl": "string"
        } ]
      } ],
      "representation": [ "xmlAttr" ],
      "max": "1",
      "id": "Extension.extension:description.id",
      "base": {
        "max": "1",
        "min": 0,
        "path": "Element.id"
      },
      "isSummary": false
    }, {
      "constraint": [ {
        "key": "ele-1",
        "human": "All FHIR elements must have a @value or children",
        "xpath": "@value|f:*|h:div",
        "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1",
        "severity": "error",
        "expression": "hasValue() or (children().count() > id.count())"
      }, {
        "key": "ext-1",
        "human": "Must have either extensions or value[x], not both",
        "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
        "source": "http://hl7.org/fhir/StructureDefinition/Extension|4.0.1",
        "severity": "error",
        "expression": "extension.exists() != value.exists()"
      } ],
      "path": "Extension.extension.extension",
      "min": 0,
      "definition": "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
      "isModifier": false,
      "short": "Additional content defined by implementations",
      "mapping": [ {
        "map": "n/a",
        "identity": "rim"
      } ],
      "slicing": {
        "rules": "open",
        "description": "Extensions are always sliced by (at least) url",
        "discriminator": [ {
          "path": "url",
          "type": "value"
        } ]
      },
      "type": [ {
        "code": "Extension"
      } ],
      "alias": [ "extensions", "user content" ],
      "max": "*",
      "id": "Extension.extension:description.extension",
      "comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
      "base": {
        "max": "*",
        "min": 0,
        "path": "Element.extension"
      },
      "isSummary": false
    }, {
      "path": "Extension.extension.url",
      "min": 1,
      "definition": "Source of the definition for the extension code - a logical name or a URL.",
      "isModifier": false,
      "short": "identifies the meaning of the extension",
      "fixedUri": "description",
      "mapping": [ {
        "map": "N/A",
        "identity": "rim"
      } ],
      "type": [ {
        "code": "http://hl7.org/fhirpath/System.String",
        "extension": [ {
          "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
          "valueUrl": "uri"
        } ]
      } ],
      "representation": [ "xmlAttr" ],
      "max": "1",
      "id": "Extension.extension:description.url",
      "comment": "The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.",
      "base": {
        "max": "1",
        "min": 1,
        "path": "Extension.url"
      },
      "isSummary": false
    }, {
      "constraint": [ {
        "key": "ele-1",
        "human": "All FHIR elements must have a @value or children",
        "xpath": "@value|f:*|h:div",
        "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1",
        "severity": "error",
        "expression": "hasValue() or (children().count() > id.count())"
      } ],
      "path": "Extension.extension.value[x]",
      "min": 0,
      "definition": "A description of the content value of the statistic.",
      "isModifier": false,
      "short": "Description of content",
      "mapping": [ {
        "map": "N/A",
        "identity": "rim"
      } ],
      "type": [ {
        "code": "string"
      } ],
      "max": "1",
      "id": "Extension.extension:description.value[x]",
      "base": {
        "max": "1",
        "min": 0,
        "path": "Extension.value[x]"
      },
      "isSummary": false
    }, {
      "constraint": [ {
        "key": "ele-1",
        "human": "All FHIR elements must have a @value or children",
        "xpath": "@value|f:*|h:div",
        "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1",
        "severity": "error",
        "expression": "hasValue() or (children().count() > id.count())"
      }, {
        "key": "ext-1",
        "human": "Must have either extensions or value[x], not both",
        "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
        "source": "http://hl7.org/fhir/StructureDefinition/Extension|4.0.1",
        "severity": "error",
        "expression": "extension.exists() != value.exists()"
      } ],
      "path": "Extension.extension",
      "requirements": "Element `Evidence.statistic.note` is part of an existing definition because parent element `Evidence.statistic` requires a cross-version extension.\nElement `Evidence.statistic.note` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.note` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
      "min": 0,
      "definition": "R4B: `Evidence.statistic.note` (new:Annotation)",
      "isModifier": false,
      "short": "R4B: Footnotes and/or explanatory notes (new)",
      "type": [ {
        "code": "Extension"
      } ],
      "sliceName": "note",
      "max": "*",
      "id": "Extension.extension:note",
      "comment": "Element `Evidence.statistic.note` is part of an existing definition because parent element `Evidence.statistic` requires a cross-version extension.\nElement `Evidence.statistic.note` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.note` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
      "base": {
        "max": "*",
        "min": 0,
        "path": "Element.extension"
      },
      "isSummary": false
    }, {
      "path": "Extension.extension.id",
      "min": 0,
      "definition": "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
      "isModifier": false,
      "short": "Unique id for inter-element referencing",
      "mapping": [ {
        "map": "n/a",
        "identity": "rim"
      } ],
      "type": [ {
        "code": "http://hl7.org/fhirpath/System.String",
        "extension": [ {
          "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
          "valueUrl": "string"
        } ]
      } ],
      "representation": [ "xmlAttr" ],
      "max": "1",
      "id": "Extension.extension:note.id",
      "base": {
        "max": "1",
        "min": 0,
        "path": "Element.id"
      },
      "isSummary": false
    }, {
      "constraint": [ {
        "key": "ele-1",
        "human": "All FHIR elements must have a @value or children",
        "xpath": "@value|f:*|h:div",
        "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1",
        "severity": "error",
        "expression": "hasValue() or (children().count() > id.count())"
      }, {
        "key": "ext-1",
        "human": "Must have either extensions or value[x], not both",
        "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
        "source": "http://hl7.org/fhir/StructureDefinition/Extension|4.0.1",
        "severity": "error",
        "expression": "extension.exists() != value.exists()"
      } ],
      "path": "Extension.extension.extension",
      "min": 0,
      "definition": "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
      "isModifier": false,
      "short": "Additional content defined by implementations",
      "mapping": [ {
        "map": "n/a",
        "identity": "rim"
      } ],
      "slicing": {
        "rules": "open",
        "description": "Extensions are always sliced by (at least) url",
        "discriminator": [ {
          "path": "url",
          "type": "value"
        } ]
      },
      "type": [ {
        "code": "Extension"
      } ],
      "alias": [ "extensions", "user content" ],
      "max": "*",
      "id": "Extension.extension:note.extension",
      "comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
      "base": {
        "max": "*",
        "min": 0,
        "path": "Element.extension"
      },
      "isSummary": false
    }, {
      "path": "Extension.extension.url",
      "min": 1,
      "definition": "Source of the definition for the extension code - a logical name or a URL.",
      "isModifier": false,
      "short": "identifies the meaning of the extension",
      "fixedUri": "note",
      "mapping": [ {
        "map": "N/A",
        "identity": "rim"
      } ],
      "type": [ {
        "code": "http://hl7.org/fhirpath/System.String",
        "extension": [ {
          "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
          "valueUrl": "uri"
        } ]
      } ],
      "representation": [ "xmlAttr" ],
      "max": "1",
      "id": "Extension.extension:note.url",
      "comment": "The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.",
      "base": {
        "max": "1",
        "min": 1,
        "path": "Extension.url"
      },
      "isSummary": false
    }, {
      "constraint": [ {
        "key": "ele-1",
        "human": "All FHIR elements must have a @value or children",
        "xpath": "@value|f:*|h:div",
        "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1",
        "severity": "error",
        "expression": "hasValue() or (children().count() > id.count())"
      } ],
      "path": "Extension.extension.value[x]",
      "min": 0,
      "definition": "Footnotes and/or explanatory notes.",
      "isModifier": false,
      "short": "Footnotes and/or explanatory notes",
      "mapping": [ {
        "map": "N/A",
        "identity": "rim"
      } ],
      "type": [ {
        "code": "Annotation"
      } ],
      "max": "1",
      "id": "Extension.extension:note.value[x]",
      "base": {
        "max": "1",
        "min": 0,
        "path": "Extension.value[x]"
      },
      "isSummary": false
    }, {
      "constraint": [ {
        "key": "ele-1",
        "human": "All FHIR elements must have a @value or children",
        "xpath": "@value|f:*|h:div",
        "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1",
        "severity": "error",
        "expression": "hasValue() or (children().count() > id.count())"
      }, {
        "key": "ext-1",
        "human": "Must have either extensions or value[x], not both",
        "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
        "source": "http://hl7.org/fhir/StructureDefinition/Extension|4.0.1",
        "severity": "error",
        "expression": "extension.exists() != value.exists()"
      } ],
      "path": "Extension.extension",
      "requirements": "Element `Evidence.statistic.statisticType` is part of an existing definition because parent element `Evidence.statistic` requires a cross-version extension.\nElement `Evidence.statistic.statisticType` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.statisticType` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
      "min": 0,
      "definition": "R4B: `Evidence.statistic.statisticType` (new:CodeableConcept)",
      "isModifier": false,
      "short": "R4B: Type of statistic, eg relative risk (new)",
      "type": [ {
        "code": "Extension"
      } ],
      "sliceName": "statisticType",
      "max": "1",
      "id": "Extension.extension:statisticType",
      "comment": "Element `Evidence.statistic.statisticType` is part of an existing definition because parent element `Evidence.statistic` requires a cross-version extension.\nElement `Evidence.statistic.statisticType` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.statisticType` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
      "base": {
        "max": "*",
        "min": 0,
        "path": "Element.extension"
      },
      "isSummary": false
    }, {
      "path": "Extension.extension.id",
      "min": 0,
      "definition": "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
      "isModifier": false,
      "short": "Unique id for inter-element referencing",
      "mapping": [ {
        "map": "n/a",
        "identity": "rim"
      } ],
      "type": [ {
        "code": "http://hl7.org/fhirpath/System.String",
        "extension": [ {
          "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
          "valueUrl": "string"
        } ]
      } ],
      "representation": [ "xmlAttr" ],
      "max": "1",
      "id": "Extension.extension:statisticType.id",
      "base": {
        "max": "1",
        "min": 0,
        "path": "Element.id"
      },
      "isSummary": false
    }, {
      "constraint": [ {
        "key": "ele-1",
        "human": "All FHIR elements must have a @value or children",
        "xpath": "@value|f:*|h:div",
        "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1",
        "severity": "error",
        "expression": "hasValue() or (children().count() > id.count())"
      }, {
        "key": "ext-1",
        "human": "Must have either extensions or value[x], not both",
        "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
        "source": "http://hl7.org/fhir/StructureDefinition/Extension|4.0.1",
        "severity": "error",
        "expression": "extension.exists() != value.exists()"
      } ],
      "path": "Extension.extension.extension",
      "min": 0,
      "definition": "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
      "isModifier": false,
      "short": "Additional content defined by implementations",
      "mapping": [ {
        "map": "n/a",
        "identity": "rim"
      } ],
      "slicing": {
        "rules": "open",
        "description": "Extensions are always sliced by (at least) url",
        "discriminator": [ {
          "path": "url",
          "type": "value"
        } ]
      },
      "type": [ {
        "code": "Extension"
      } ],
      "alias": [ "extensions", "user content" ],
      "max": "*",
      "id": "Extension.extension:statisticType.extension",
      "comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
      "base": {
        "max": "*",
        "min": 0,
        "path": "Element.extension"
      },
      "isSummary": false
    }, {
      "path": "Extension.extension.url",
      "min": 1,
      "definition": "Source of the definition for the extension code - a logical name or a URL.",
      "isModifier": false,
      "short": "identifies the meaning of the extension",
      "fixedUri": "statisticType",
      "mapping": [ {
        "map": "N/A",
        "identity": "rim"
      } ],
      "type": [ {
        "code": "http://hl7.org/fhirpath/System.String",
        "extension": [ {
          "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
          "valueUrl": "uri"
        } ]
      } ],
      "representation": [ "xmlAttr" ],
      "max": "1",
      "id": "Extension.extension:statisticType.url",
      "comment": "The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.",
      "base": {
        "max": "1",
        "min": 1,
        "path": "Extension.url"
      },
      "isSummary": false
    }, {
      "constraint": [ {
        "key": "ele-1",
        "human": "All FHIR elements must have a @value or children",
        "xpath": "@value|f:*|h:div",
        "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1",
        "severity": "error",
        "expression": "hasValue() or (children().count() > id.count())"
      } ],
      "path": "Extension.extension.value[x]",
      "min": 0,
      "definition": "Type of statistic, eg relative risk.",
      "isModifier": false,
      "short": "Type of statistic, eg relative risk",
      "mapping": [ {
        "map": "N/A",
        "identity": "rim"
      } ],
      "type": [ {
        "code": "CodeableConcept"
      } ],
      "binding": {
        "strength": "extensible",
        "valueSet": "http://hl7.org/fhir/uv/xver/ValueSet/R4B-statistic-type-for-R4|0.1.0"
      },
      "max": "1",
      "id": "Extension.extension:statisticType.value[x]",
      "base": {
        "max": "1",
        "min": 0,
        "path": "Extension.value[x]"
      },
      "isSummary": false
    }, {
      "constraint": [ {
        "key": "ele-1",
        "human": "All FHIR elements must have a @value or children",
        "xpath": "@value|f:*|h:div",
        "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1",
        "severity": "error",
        "expression": "hasValue() or (children().count() > id.count())"
      }, {
        "key": "ext-1",
        "human": "Must have either extensions or value[x], not both",
        "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
        "source": "http://hl7.org/fhir/StructureDefinition/Extension|4.0.1",
        "severity": "error",
        "expression": "extension.exists() != value.exists()"
      } ],
      "path": "Extension.extension",
      "requirements": "Element `Evidence.statistic.category` is part of an existing definition because parent element `Evidence.statistic` requires a cross-version extension.\nElement `Evidence.statistic.category` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.category` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
      "min": 0,
      "definition": "R4B: `Evidence.statistic.category` (new:CodeableConcept)",
      "isModifier": false,
      "short": "R4B: Associated category for categorical variable (new)",
      "type": [ {
        "code": "Extension"
      } ],
      "sliceName": "category",
      "max": "1",
      "id": "Extension.extension:category",
      "comment": "Element `Evidence.statistic.category` is part of an existing definition because parent element `Evidence.statistic` requires a cross-version extension.\nElement `Evidence.statistic.category` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.category` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).\nSimple strings can be used for descriptive purposes. Exact matching to EvidenceVariable.category.name for the Evidence.variableDefinition[variableRole=measuredVariable].observed=Reference(EvidenceVariable) could facilitate validation within datasets.",
      "base": {
        "max": "*",
        "min": 0,
        "path": "Element.extension"
      },
      "isSummary": false
    }, {
      "path": "Extension.extension.id",
      "min": 0,
      "definition": "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
      "isModifier": false,
      "short": "Unique id for inter-element referencing",
      "mapping": [ {
        "map": "n/a",
        "identity": "rim"
      } ],
      "type": [ {
        "code": "http://hl7.org/fhirpath/System.String",
        "extension": [ {
          "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
          "valueUrl": "string"
        } ]
      } ],
      "representation": [ "xmlAttr" ],
      "max": "1",
      "id": "Extension.extension:category.id",
      "base": {
        "max": "1",
        "min": 0,
        "path": "Element.id"
      },
      "isSummary": false
    }, {
      "constraint": [ {
        "key": "ele-1",
        "human": "All FHIR elements must have a @value or children",
        "xpath": "@value|f:*|h:div",
        "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1",
        "severity": "error",
        "expression": "hasValue() or (children().count() > id.count())"
      }, {
        "key": "ext-1",
        "human": "Must have either extensions or value[x], not both",
        "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
        "source": "http://hl7.org/fhir/StructureDefinition/Extension|4.0.1",
        "severity": "error",
        "expression": "extension.exists() != value.exists()"
      } ],
      "path": "Extension.extension.extension",
      "min": 0,
      "definition": "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
      "isModifier": false,
      "short": "Additional content defined by implementations",
      "mapping": [ {
        "map": "n/a",
        "identity": "rim"
      } ],
      "slicing": {
        "rules": "open",
        "description": "Extensions are always sliced by (at least) url",
        "discriminator": [ {
          "path": "url",
          "type": "value"
        } ]
      },
      "type": [ {
        "code": "Extension"
      } ],
      "alias": [ "extensions", "user content" ],
      "max": "*",
      "id": "Extension.extension:category.extension",
      "comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
      "base": {
        "max": "*",
        "min": 0,
        "path": "Element.extension"
      },
      "isSummary": false
    }, {
      "path": "Extension.extension.url",
      "min": 1,
      "definition": "Source of the definition for the extension code - a logical name or a URL.",
      "isModifier": false,
      "short": "identifies the meaning of the extension",
      "fixedUri": "category",
      "mapping": [ {
        "map": "N/A",
        "identity": "rim"
      } ],
      "type": [ {
        "code": "http://hl7.org/fhirpath/System.String",
        "extension": [ {
          "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
          "valueUrl": "uri"
        } ]
      } ],
      "representation": [ "xmlAttr" ],
      "max": "1",
      "id": "Extension.extension:category.url",
      "comment": "The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.",
      "base": {
        "max": "1",
        "min": 1,
        "path": "Extension.url"
      },
      "isSummary": false
    }, {
      "constraint": [ {
        "key": "ele-1",
        "human": "All FHIR elements must have a @value or children",
        "xpath": "@value|f:*|h:div",
        "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1",
        "severity": "error",
        "expression": "hasValue() or (children().count() > id.count())"
      } ],
      "path": "Extension.extension.value[x]",
      "min": 0,
      "definition": "When the measured variable is handled categorically, the category element is used to define which category the statistic is reporting.",
      "isModifier": false,
      "short": "Associated category for categorical variable",
      "mapping": [ {
        "map": "N/A",
        "identity": "rim"
      } ],
      "type": [ {
        "code": "CodeableConcept"
      } ],
      "max": "1",
      "id": "Extension.extension:category.value[x]",
      "comment": "Simple strings can be used for descriptive purposes. Exact matching to EvidenceVariable.category.name for the Evidence.variableDefinition[variableRole=measuredVariable].observed=Reference(EvidenceVariable) could facilitate validation within datasets.",
      "base": {
        "max": "1",
        "min": 0,
        "path": "Extension.value[x]"
      },
      "isSummary": false
    }, {
      "constraint": [ {
        "key": "ele-1",
        "human": "All FHIR elements must have a @value or children",
        "xpath": "@value|f:*|h:div",
        "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1",
        "severity": "error",
        "expression": "hasValue() or (children().count() > id.count())"
      }, {
        "key": "ext-1",
        "human": "Must have either extensions or value[x], not both",
        "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
        "source": "http://hl7.org/fhir/StructureDefinition/Extension|4.0.1",
        "severity": "error",
        "expression": "extension.exists() != value.exists()"
      } ],
      "path": "Extension.extension",
      "requirements": "Element `Evidence.statistic.quantity` is part of an existing definition because parent element `Evidence.statistic` requires a cross-version extension.\nElement `Evidence.statistic.quantity` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.quantity` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
      "min": 0,
      "definition": "R4B: `Evidence.statistic.quantity` (new:Quantity)",
      "isModifier": false,
      "short": "R4B: Statistic value (new)",
      "type": [ {
        "code": "Extension"
      } ],
      "sliceName": "quantity",
      "max": "1",
      "id": "Extension.extension:quantity",
      "comment": "Element `Evidence.statistic.quantity` is part of an existing definition because parent element `Evidence.statistic` requires a cross-version extension.\nElement `Evidence.statistic.quantity` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.quantity` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
      "base": {
        "max": "*",
        "min": 0,
        "path": "Element.extension"
      },
      "isSummary": false
    }, {
      "path": "Extension.extension.id",
      "min": 0,
      "definition": "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
      "isModifier": false,
      "short": "Unique id for inter-element referencing",
      "mapping": [ {
        "map": "n/a",
        "identity": "rim"
      } ],
      "type": [ {
        "code": "http://hl7.org/fhirpath/System.String",
        "extension": [ {
          "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
          "valueUrl": "string"
        } ]
      } ],
      "representation": [ "xmlAttr" ],
      "max": "1",
      "id": "Extension.extension:quantity.id",
      "base": {
        "max": "1",
        "min": 0,
        "path": "Element.id"
      },
      "isSummary": false
    }, {
      "constraint": [ {
        "key": "ele-1",
        "human": "All FHIR elements must have a @value or children",
        "xpath": "@value|f:*|h:div",
        "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1",
        "severity": "error",
        "expression": "hasValue() or (children().count() > id.count())"
      }, {
        "key": "ext-1",
        "human": "Must have either extensions or value[x], not both",
        "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
        "source": "http://hl7.org/fhir/StructureDefinition/Extension|4.0.1",
        "severity": "error",
        "expression": "extension.exists() != value.exists()"
      } ],
      "path": "Extension.extension.extension",
      "min": 0,
      "definition": "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
      "isModifier": false,
      "short": "Additional content defined by implementations",
      "mapping": [ {
        "map": "n/a",
        "identity": "rim"
      } ],
      "slicing": {
        "rules": "open",
        "description": "Extensions are always sliced by (at least) url",
        "discriminator": [ {
          "path": "url",
          "type": "value"
        } ]
      },
      "type": [ {
        "code": "Extension"
      } ],
      "alias": [ "extensions", "user content" ],
      "max": "*",
      "id": "Extension.extension:quantity.extension",
      "comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
      "base": {
        "max": "*",
        "min": 0,
        "path": "Element.extension"
      },
      "isSummary": false
    }, {
      "path": "Extension.extension.url",
      "min": 1,
      "definition": "Source of the definition for the extension code - a logical name or a URL.",
      "isModifier": false,
      "short": "identifies the meaning of the extension",
      "fixedUri": "quantity",
      "mapping": [ {
        "map": "N/A",
        "identity": "rim"
      } ],
      "type": [ {
        "code": "http://hl7.org/fhirpath/System.String",
        "extension": [ {
          "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
          "valueUrl": "uri"
        } ]
      } ],
      "representation": [ "xmlAttr" ],
      "max": "1",
      "id": "Extension.extension:quantity.url",
      "comment": "The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.",
      "base": {
        "max": "1",
        "min": 1,
        "path": "Extension.url"
      },
      "isSummary": false
    }, {
      "constraint": [ {
        "key": "ele-1",
        "human": "All FHIR elements must have a @value or children",
        "xpath": "@value|f:*|h:div",
        "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1",
        "severity": "error",
        "expression": "hasValue() or (children().count() > id.count())"
      } ],
      "path": "Extension.extension.value[x]",
      "min": 0,
      "definition": "Statistic value.",
      "isModifier": false,
      "short": "Statistic value",
      "mapping": [ {
        "map": "N/A",
        "identity": "rim"
      } ],
      "type": [ {
        "code": "Quantity"
      } ],
      "max": "1",
      "id": "Extension.extension:quantity.value[x]",
      "base": {
        "max": "1",
        "min": 0,
        "path": "Extension.value[x]"
      },
      "isSummary": false
    }, {
      "constraint": [ {
        "key": "ele-1",
        "human": "All FHIR elements must have a @value or children",
        "xpath": "@value|f:*|h:div",
        "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1",
        "severity": "error",
        "expression": "hasValue() or (children().count() > id.count())"
      }, {
        "key": "ext-1",
        "human": "Must have either extensions or value[x], not both",
        "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
        "source": "http://hl7.org/fhir/StructureDefinition/Extension|4.0.1",
        "severity": "error",
        "expression": "extension.exists() != value.exists()"
      } ],
      "path": "Extension.extension",
      "requirements": "Element `Evidence.statistic.numberOfEvents` is part of an existing definition because parent element `Evidence.statistic` requires a cross-version extension.\nElement `Evidence.statistic.numberOfEvents` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.numberOfEvents` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
      "min": 0,
      "definition": "R4B: `Evidence.statistic.numberOfEvents` (new:unsignedInt)",
      "isModifier": false,
      "short": "R4B: The number of events associated with the statistic (new)",
      "type": [ {
        "code": "Extension"
      } ],
      "sliceName": "numberOfEvents",
      "max": "1",
      "id": "Extension.extension:numberOfEvents",
      "comment": "Element `Evidence.statistic.numberOfEvents` is part of an existing definition because parent element `Evidence.statistic` requires a cross-version extension.\nElement `Evidence.statistic.numberOfEvents` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.numberOfEvents` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).\nWhen the number of events is the statistic, use Evidence.statistic.quantity and set Evidence.statistic.type.coding.code=C25463 and Evidence.statistic.type.coding.display=Count. When the statistic is an Event Rate (where individual participants may have 2 or more events), use Evidence.statistic.numberOfEvents to record the total number of events rather than the number of participants with events.",
      "base": {
        "max": "*",
        "min": 0,
        "path": "Element.extension"
      },
      "isSummary": false
    }, {
      "path": "Extension.extension.id",
      "min": 0,
      "definition": "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
      "isModifier": false,
      "short": "Unique id for inter-element referencing",
      "mapping": [ {
        "map": "n/a",
        "identity": "rim"
      } ],
      "type": [ {
        "code": "http://hl7.org/fhirpath/System.String",
        "extension": [ {
          "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
          "valueUrl": "string"
        } ]
      } ],
      "representation": [ "xmlAttr" ],
      "max": "1",
      "id": "Extension.extension:numberOfEvents.id",
      "base": {
        "max": "1",
        "min": 0,
        "path": "Element.id"
      },
      "isSummary": false
    }, {
      "constraint": [ {
        "key": "ele-1",
        "human": "All FHIR elements must have a @value or children",
        "xpath": "@value|f:*|h:div",
        "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1",
        "severity": "error",
        "expression": "hasValue() or (children().count() > id.count())"
      }, {
        "key": "ext-1",
        "human": "Must have either extensions or value[x], not both",
        "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
        "source": "http://hl7.org/fhir/StructureDefinition/Extension|4.0.1",
        "severity": "error",
        "expression": "extension.exists() != value.exists()"
      } ],
      "path": "Extension.extension.extension",
      "min": 0,
      "definition": "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
      "isModifier": false,
      "short": "Additional content defined by implementations",
      "mapping": [ {
        "map": "n/a",
        "identity": "rim"
      } ],
      "slicing": {
        "rules": "open",
        "description": "Extensions are always sliced by (at least) url",
        "discriminator": [ {
          "path": "url",
          "type": "value"
        } ]
      },
      "type": [ {
        "code": "Extension"
      } ],
      "alias": [ "extensions", "user content" ],
      "max": "*",
      "id": "Extension.extension:numberOfEvents.extension",
      "comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
      "base": {
        "max": "*",
        "min": 0,
        "path": "Element.extension"
      },
      "isSummary": false
    }, {
      "path": "Extension.extension.url",
      "min": 1,
      "definition": "Source of the definition for the extension code - a logical name or a URL.",
      "isModifier": false,
      "short": "identifies the meaning of the extension",
      "fixedUri": "numberOfEvents",
      "mapping": [ {
        "map": "N/A",
        "identity": "rim"
      } ],
      "type": [ {
        "code": "http://hl7.org/fhirpath/System.String",
        "extension": [ {
          "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
          "valueUrl": "uri"
        } ]
      } ],
      "representation": [ "xmlAttr" ],
      "max": "1",
      "id": "Extension.extension:numberOfEvents.url",
      "comment": "The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.",
      "base": {
        "max": "1",
        "min": 1,
        "path": "Extension.url"
      },
      "isSummary": false
    }, {
      "constraint": [ {
        "key": "ele-1",
        "human": "All FHIR elements must have a @value or children",
        "xpath": "@value|f:*|h:div",
        "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1",
        "severity": "error",
        "expression": "hasValue() or (children().count() > id.count())"
      } ],
      "path": "Extension.extension.value[x]",
      "min": 0,
      "definition": "The number of events associated with the statistic, where the unit of analysis is different from numberAffected, sampleSize.knownDataCount and sampleSize.numberOfParticipants.",
      "isModifier": false,
      "short": "The number of events associated with the statistic",
      "mapping": [ {
        "map": "N/A",
        "identity": "rim"
      } ],
      "type": [ {
        "code": "unsignedInt"
      } ],
      "max": "1",
      "id": "Extension.extension:numberOfEvents.value[x]",
      "comment": "When the number of events is the statistic, use Evidence.statistic.quantity and set Evidence.statistic.type.coding.code=C25463 and Evidence.statistic.type.coding.display=Count. When the statistic is an Event Rate (where individual participants may have 2 or more events), use Evidence.statistic.numberOfEvents to record the total number of events rather than the number of participants with events.",
      "base": {
        "max": "1",
        "min": 0,
        "path": "Extension.value[x]"
      },
      "isSummary": false
    }, {
      "constraint": [ {
        "key": "ele-1",
        "human": "All FHIR elements must have a @value or children",
        "xpath": "@value|f:*|h:div",
        "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1",
        "severity": "error",
        "expression": "hasValue() or (children().count() > id.count())"
      }, {
        "key": "ext-1",
        "human": "Must have either extensions or value[x], not both",
        "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
        "source": "http://hl7.org/fhir/StructureDefinition/Extension|4.0.1",
        "severity": "error",
        "expression": "extension.exists() != value.exists()"
      } ],
      "path": "Extension.extension",
      "requirements": "Element `Evidence.statistic.numberAffected` is part of an existing definition because parent element `Evidence.statistic` requires a cross-version extension.\nElement `Evidence.statistic.numberAffected` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.numberAffected` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
      "min": 0,
      "definition": "R4B: `Evidence.statistic.numberAffected` (new:unsignedInt)",
      "isModifier": false,
      "short": "R4B: The number of participants affected (new)",
      "type": [ {
        "code": "Extension"
      } ],
      "sliceName": "numberAffected",
      "max": "1",
      "id": "Extension.extension:numberAffected",
      "comment": "Element `Evidence.statistic.numberAffected` is part of an existing definition because parent element `Evidence.statistic` requires a cross-version extension.\nElement `Evidence.statistic.numberAffected` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.numberAffected` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).\nWhen the number affected is the statistic, use Evidence.statistic.quantity and set Evidence.statistic.type.coding.code=C25463 and Evidence.statistic.type.coding.display=Count. When the statistic is a Proportion, use Evidence.statistic.numberAffected and enter an integer as the value. When the statistic is an Event Rate (where individual participants may have 2 or more events), use Evidence.statistic.numberAffected to record the number of participants with events rather than the total number of events.",
      "base": {
        "max": "*",
        "min": 0,
        "path": "Element.extension"
      },
      "isSummary": false
    }, {
      "path": "Extension.extension.id",
      "min": 0,
      "definition": "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
      "isModifier": false,
      "short": "Unique id for inter-element referencing",
      "mapping": [ {
        "map": "n/a",
        "identity": "rim"
      } ],
      "type": [ {
        "code": "http://hl7.org/fhirpath/System.String",
        "extension": [ {
          "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
          "valueUrl": "string"
        } ]
      } ],
      "representation": [ "xmlAttr" ],
      "max": "1",
      "id": "Extension.extension:numberAffected.id",
      "base": {
        "max": "1",
        "min": 0,
        "path": "Element.id"
      },
      "isSummary": false
    }, {
      "constraint": [ {
        "key": "ele-1",
        "human": "All FHIR elements must have a @value or children",
        "xpath": "@value|f:*|h:div",
        "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1",
        "severity": "error",
        "expression": "hasValue() or (children().count() > id.count())"
      }, {
        "key": "ext-1",
        "human": "Must have either extensions or value[x], not both",
        "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
        "source": "http://hl7.org/fhir/StructureDefinition/Extension|4.0.1",
        "severity": "error",
        "expression": "extension.exists() != value.exists()"
      } ],
      "path": "Extension.extension.extension",
      "min": 0,
      "definition": "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
      "isModifier": false,
      "short": "Additional content defined by implementations",
      "mapping": [ {
        "map": "n/a",
        "identity": "rim"
      } ],
      "slicing": {
        "rules": "open",
        "description": "Extensions are always sliced by (at least) url",
        "discriminator": [ {
          "path": "url",
          "type": "value"
        } ]
      },
      "type": [ {
        "code": "Extension"
      } ],
      "alias": [ "extensions", "user content" ],
      "max": "*",
      "id": "Extension.extension:numberAffected.extension",
      "comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
      "base": {
        "max": "*",
        "min": 0,
        "path": "Element.extension"
      },
      "isSummary": false
    }, {
      "path": "Extension.extension.url",
      "min": 1,
      "definition": "Source of the definition for the extension code - a logical name or a URL.",
      "isModifier": false,
      "short": "identifies the meaning of the extension",
      "fixedUri": "numberAffected",
      "mapping": [ {
        "map": "N/A",
        "identity": "rim"
      } ],
      "type": [ {
        "code": "http://hl7.org/fhirpath/System.String",
        "extension": [ {
          "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
          "valueUrl": "uri"
        } ]
      } ],
      "representation": [ "xmlAttr" ],
      "max": "1",
      "id": "Extension.extension:numberAffected.url",
      "comment": "The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.",
      "base": {
        "max": "1",
        "min": 1,
        "path": "Extension.url"
      },
      "isSummary": false
    }, {
      "constraint": [ {
        "key": "ele-1",
        "human": "All FHIR elements must have a @value or children",
        "xpath": "@value|f:*|h:div",
        "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1",
        "severity": "error",
        "expression": "hasValue() or (children().count() > id.count())"
      } ],
      "path": "Extension.extension.value[x]",
      "min": 0,
      "definition": "The number of participants affected where the unit of analysis is the same as sampleSize.knownDataCount and sampleSize.numberOfParticipants.",
      "isModifier": false,
      "short": "The number of participants affected",
      "mapping": [ {
        "map": "N/A",
        "identity": "rim"
      } ],
      "type": [ {
        "code": "unsignedInt"
      } ],
      "max": "1",
      "id": "Extension.extension:numberAffected.value[x]",
      "comment": "When the number affected is the statistic, use Evidence.statistic.quantity and set Evidence.statistic.type.coding.code=C25463 and Evidence.statistic.type.coding.display=Count. When the statistic is a Proportion, use Evidence.statistic.numberAffected and enter an integer as the value. When the statistic is an Event Rate (where individual participants may have 2 or more events), use Evidence.statistic.numberAffected to record the number of participants with events rather than the total number of events.",
      "base": {
        "max": "1",
        "min": 0,
        "path": "Extension.value[x]"
      },
      "isSummary": false
    }, {
      "constraint": [ {
        "key": "ele-1",
        "human": "All FHIR elements must have a @value or children",
        "xpath": "@value|f:*|h:div",
        "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1",
        "severity": "error",
        "expression": "hasValue() or (children().count() > id.count())"
      }, {
        "key": "ext-1",
        "human": "Must have either extensions or value[x], not both",
        "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
        "source": "http://hl7.org/fhir/StructureDefinition/Extension|4.0.1",
        "severity": "error",
        "expression": "extension.exists() != value.exists()"
      } ],
      "path": "Extension.extension",
      "requirements": "Element `Evidence.statistic.sampleSize` is part of an existing definition because parent element `Evidence.statistic` requires a cross-version extension.\nElement `Evidence.statistic.sampleSize` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.sampleSize` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
      "min": 0,
      "definition": "R4B: `Evidence.statistic.sampleSize` (new:BackboneElement)",
      "isModifier": false,
      "short": "R4B: Number of samples in the statistic (new)",
      "type": [ {
        "code": "Extension"
      } ],
      "sliceName": "sampleSize",
      "max": "1",
      "id": "Extension.extension:sampleSize",
      "comment": "Element `Evidence.statistic.sampleSize` is part of an existing definition because parent element `Evidence.statistic` requires a cross-version extension.\nElement `Evidence.statistic.sampleSize` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.sampleSize` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
      "base": {
        "max": "*",
        "min": 0,
        "path": "Element.extension"
      },
      "isSummary": false
    }, {
      "path": "Extension.extension.id",
      "min": 0,
      "definition": "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
      "isModifier": false,
      "short": "Unique id for inter-element referencing",
      "mapping": [ {
        "map": "n/a",
        "identity": "rim"
      } ],
      "type": [ {
        "code": "http://hl7.org/fhirpath/System.String",
        "extension": [ {
          "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
          "valueUrl": "string"
        } ]
      } ],
      "representation": [ "xmlAttr" ],
      "max": "1",
      "id": "Extension.extension:sampleSize.id",
      "base": {
        "max": "1",
        "min": 0,
        "path": "Element.id"
      },
      "isSummary": false
    }, {
      "constraint": [ {
        "key": "ele-1",
        "human": "All FHIR elements must have a @value or children",
        "xpath": "@value|f:*|h:div",
        "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1",
        "severity": "error",
        "expression": "hasValue() or (children().count() > id.count())"
      }, {
        "key": "ext-1",
        "human": "Must have either extensions or value[x], not both",
        "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
        "source": "http://hl7.org/fhir/StructureDefinition/Extension|4.0.1",
        "severity": "error",
        "expression": "extension.exists() != value.exists()"
      } ],
      "path": "Extension.extension.extension",
      "min": 0,
      "definition": "An Extension",
      "isModifier": false,
      "short": "Extension",
      "slicing": {
        "rules": "open",
        "ordered": false,
        "description": "Extensions are always sliced by (at least) url",
        "discriminator": [ {
          "path": "url",
          "type": "value"
        } ]
      },
      "type": [ {
        "code": "Extension"
      } ],
      "max": "*",
      "id": "Extension.extension:sampleSize.extension",
      "base": {
        "max": "*",
        "min": 0,
        "path": "Element.extension"
      },
      "isSummary": false
    }, {
      "constraint": [ {
        "key": "ele-1",
        "human": "All FHIR elements must have a @value or children",
        "xpath": "@value|f:*|h:div",
        "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1",
        "severity": "error",
        "expression": "hasValue() or (children().count() > id.count())"
      }, {
        "key": "ext-1",
        "human": "Must have either extensions or value[x], not both",
        "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
        "source": "http://hl7.org/fhir/StructureDefinition/Extension|4.0.1",
        "severity": "error",
        "expression": "extension.exists() != value.exists()"
      } ],
      "path": "Extension.extension.extension",
      "requirements": "Element `Evidence.statistic.sampleSize.description` is part of an existing definition because parent element `Evidence.statistic.sampleSize` requires a cross-version extension.\nElement `Evidence.statistic.sampleSize.description` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.sampleSize.description` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
      "min": 0,
      "definition": "R4B: `Evidence.statistic.sampleSize.description` (new:string)",
      "isModifier": false,
      "short": "R4B: Textual description of sample size for statistic (new)",
      "type": [ {
        "code": "Extension"
      } ],
      "sliceName": "description",
      "max": "1",
      "id": "Extension.extension:sampleSize.extension:description",
      "comment": "Element `Evidence.statistic.sampleSize.description` is part of an existing definition because parent element `Evidence.statistic.sampleSize` requires a cross-version extension.\nElement `Evidence.statistic.sampleSize.description` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.sampleSize.description` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
      "base": {
        "max": "*",
        "min": 0,
        "path": "Element.extension"
      },
      "isSummary": false
    }, {
      "path": "Extension.extension.extension.id",
      "min": 0,
      "definition": "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
      "isModifier": false,
      "short": "Unique id for inter-element referencing",
      "mapping": [ {
        "map": "n/a",
        "identity": "rim"
      } ],
      "type": [ {
        "code": "http://hl7.org/fhirpath/System.String",
        "extension": [ {
          "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
          "valueUrl": "string"
        } ]
      } ],
      "representation": [ "xmlAttr" ],
      "max": "1",
      "id": "Extension.extension:sampleSize.extension:description.id",
      "base": {
        "max": "1",
        "min": 0,
        "path": "Element.id"
      },
      "isSummary": false
    }, {
      "constraint": [ {
        "key": "ele-1",
        "human": "All FHIR elements must have a @value or children",
        "xpath": "@value|f:*|h:div",
        "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1",
        "severity": "error",
        "expression": "hasValue() or (children().count() > id.count())"
      }, {
        "key": "ext-1",
        "human": "Must have either extensions or value[x], not both",
        "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
        "source": "http://hl7.org/fhir/StructureDefinition/Extension|4.0.1",
        "severity": "error",
        "expression": "extension.exists() != value.exists()"
      } ],
      "path": "Extension.extension.extension.extension",
      "min": 0,
      "definition": "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
      "isModifier": false,
      "short": "Additional content defined by implementations",
      "mapping": [ {
        "map": "n/a",
        "identity": "rim"
      } ],
      "slicing": {
        "rules": "open",
        "description": "Extensions are always sliced by (at least) url",
        "discriminator": [ {
          "path": "url",
          "type": "value"
        } ]
      },
      "type": [ {
        "code": "Extension"
      } ],
      "alias": [ "extensions", "user content" ],
      "max": "*",
      "id": "Extension.extension:sampleSize.extension:description.extension",
      "comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
      "base": {
        "max": "*",
        "min": 0,
        "path": "Element.extension"
      },
      "isSummary": false
    }, {
      "path": "Extension.extension.extension.url",
      "min": 1,
      "definition": "Source of the definition for the extension code - a logical name or a URL.",
      "isModifier": false,
      "short": "identifies the meaning of the extension",
      "fixedUri": "description",
      "mapping": [ {
        "map": "N/A",
        "identity": "rim"
      } ],
      "type": [ {
        "code": "http://hl7.org/fhirpath/System.String",
        "extension": [ {
          "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
          "valueUrl": "uri"
        } ]
      } ],
      "representation": [ "xmlAttr" ],
      "max": "1",
      "id": "Extension.extension:sampleSize.extension:description.url",
      "comment": "The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.",
      "base": {
        "max": "1",
        "min": 1,
        "path": "Extension.url"
      },
      "isSummary": false
    }, {
      "constraint": [ {
        "key": "ele-1",
        "human": "All FHIR elements must have a @value or children",
        "xpath": "@value|f:*|h:div",
        "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1",
        "severity": "error",
        "expression": "hasValue() or (children().count() > id.count())"
      } ],
      "path": "Extension.extension.extension.value[x]",
      "min": 0,
      "definition": "Human-readable summary of population sample size.",
      "isModifier": false,
      "short": "Textual description of sample size for statistic",
      "mapping": [ {
        "map": "N/A",
        "identity": "rim"
      } ],
      "type": [ {
        "code": "string"
      } ],
      "max": "1",
      "id": "Extension.extension:sampleSize.extension:description.value[x]",
      "base": {
        "max": "1",
        "min": 0,
        "path": "Extension.value[x]"
      },
      "isSummary": false
    }, {
      "constraint": [ {
        "key": "ele-1",
        "human": "All FHIR elements must have a @value or children",
        "xpath": "@value|f:*|h:div",
        "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1",
        "severity": "error",
        "expression": "hasValue() or (children().count() > id.count())"
      }, {
        "key": "ext-1",
        "human": "Must have either extensions or value[x], not both",
        "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
        "source": "http://hl7.org/fhir/StructureDefinition/Extension|4.0.1",
        "severity": "error",
        "expression": "extension.exists() != value.exists()"
      } ],
      "path": "Extension.extension.extension",
      "requirements": "Element `Evidence.statistic.sampleSize.note` is part of an existing definition because parent element `Evidence.statistic.sampleSize` requires a cross-version extension.\nElement `Evidence.statistic.sampleSize.note` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.sampleSize.note` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
      "min": 0,
      "definition": "R4B: `Evidence.statistic.sampleSize.note` (new:Annotation)",
      "isModifier": false,
      "short": "R4B: Footnote or explanatory note about the sample size (new)",
      "type": [ {
        "code": "Extension"
      } ],
      "sliceName": "note",
      "max": "*",
      "id": "Extension.extension:sampleSize.extension:note",
      "comment": "Element `Evidence.statistic.sampleSize.note` is part of an existing definition because parent element `Evidence.statistic.sampleSize` requires a cross-version extension.\nElement `Evidence.statistic.sampleSize.note` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.sampleSize.note` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
      "base": {
        "max": "*",
        "min": 0,
        "path": "Element.extension"
      },
      "isSummary": false
    }, {
      "path": "Extension.extension.extension.id",
      "min": 0,
      "definition": "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
      "isModifier": false,
      "short": "Unique id for inter-element referencing",
      "mapping": [ {
        "map": "n/a",
        "identity": "rim"
      } ],
      "type": [ {
        "code": "http://hl7.org/fhirpath/System.String",
        "extension": [ {
          "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
          "valueUrl": "string"
        } ]
      } ],
      "representation": [ "xmlAttr" ],
      "max": "1",
      "id": "Extension.extension:sampleSize.extension:note.id",
      "base": {
        "max": "1",
        "min": 0,
        "path": "Element.id"
      },
      "isSummary": false
    }, {
      "constraint": [ {
        "key": "ele-1",
        "human": "All FHIR elements must have a @value or children",
        "xpath": "@value|f:*|h:div",
        "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1",
        "severity": "error",
        "expression": "hasValue() or (children().count() > id.count())"
      }, {
        "key": "ext-1",
        "human": "Must have either extensions or value[x], not both",
        "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
        "source": "http://hl7.org/fhir/StructureDefinition/Extension|4.0.1",
        "severity": "error",
        "expression": "extension.exists() != value.exists()"
      } ],
      "path": "Extension.extension.extension.extension",
      "min": 0,
      "definition": "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
      "isModifier": false,
      "short": "Additional content defined by implementations",
      "mapping": [ {
        "map": "n/a",
        "identity": "rim"
      } ],
      "slicing": {
        "rules": "open",
        "description": "Extensions are always sliced by (at least) url",
        "discriminator": [ {
          "path": "url",
          "type": "value"
        } ]
      },
      "type": [ {
        "code": "Extension"
      } ],
      "alias": [ "extensions", "user content" ],
      "max": "*",
      "id": "Extension.extension:sampleSize.extension:note.extension",
      "comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
      "base": {
        "max": "*",
        "min": 0,
        "path": "Element.extension"
      },
      "isSummary": false
    }, {
      "path": "Extension.extension.extension.url",
      "min": 1,
      "definition": "Source of the definition for the extension code - a logical name or a URL.",
      "isModifier": false,
      "short": "identifies the meaning of the extension",
      "fixedUri": "note",
      "mapping": [ {
        "map": "N/A",
        "identity": "rim"
      } ],
      "type": [ {
        "code": "http://hl7.org/fhirpath/System.String",
        "extension": [ {
          "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
          "valueUrl": "uri"
        } ]
      } ],
      "representation": [ "xmlAttr" ],
      "max": "1",
      "id": "Extension.extension:sampleSize.extension:note.url",
      "comment": "The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.",
      "base": {
        "max": "1",
        "min": 1,
        "path": "Extension.url"
      },
      "isSummary": false
    }, {
      "constraint": [ {
        "key": "ele-1",
        "human": "All FHIR elements must have a @value or children",
        "xpath": "@value|f:*|h:div",
        "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1",
        "severity": "error",
        "expression": "hasValue() or (children().count() > id.count())"
      } ],
      "path": "Extension.extension.extension.value[x]",
      "min": 0,
      "definition": "Footnote or explanatory note about the sample size.",
      "isModifier": false,
      "short": "Footnote or explanatory note about the sample size",
      "mapping": [ {
        "map": "N/A",
        "identity": "rim"
      } ],
      "type": [ {
        "code": "Annotation"
      } ],
      "max": "1",
      "id": "Extension.extension:sampleSize.extension:note.value[x]",
      "base": {
        "max": "1",
        "min": 0,
        "path": "Extension.value[x]"
      },
      "isSummary": false
    }, {
      "constraint": [ {
        "key": "ele-1",
        "human": "All FHIR elements must have a @value or children",
        "xpath": "@value|f:*|h:div",
        "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1",
        "severity": "error",
        "expression": "hasValue() or (children().count() > id.count())"
      }, {
        "key": "ext-1",
        "human": "Must have either extensions or value[x], not both",
        "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
        "source": "http://hl7.org/fhir/StructureDefinition/Extension|4.0.1",
        "severity": "error",
        "expression": "extension.exists() != value.exists()"
      } ],
      "path": "Extension.extension.extension",
      "requirements": "Element `Evidence.statistic.sampleSize.numberOfStudies` is part of an existing definition because parent element `Evidence.statistic.sampleSize` requires a cross-version extension.\nElement `Evidence.statistic.sampleSize.numberOfStudies` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.sampleSize.numberOfStudies` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
      "min": 0,
      "definition": "R4B: `Evidence.statistic.sampleSize.numberOfStudies` (new:unsignedInt)",
      "isModifier": false,
      "short": "R4B: Number of contributing studies (new)",
      "type": [ {
        "code": "Extension"
      } ],
      "sliceName": "numberOfStudies",
      "max": "1",
      "id": "Extension.extension:sampleSize.extension:numberOfStudies",
      "comment": "Element `Evidence.statistic.sampleSize.numberOfStudies` is part of an existing definition because parent element `Evidence.statistic.sampleSize` requires a cross-version extension.\nElement `Evidence.statistic.sampleSize.numberOfStudies` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.sampleSize.numberOfStudies` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
      "base": {
        "max": "*",
        "min": 0,
        "path": "Element.extension"
      },
      "isSummary": false
    }, {
      "path": "Extension.extension.extension.id",
      "min": 0,
      "definition": "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
      "isModifier": false,
      "short": "Unique id for inter-element referencing",
      "mapping": [ {
        "map": "n/a",
        "identity": "rim"
      } ],
      "type": [ {
        "code": "http://hl7.org/fhirpath/System.String",
        "extension": [ {
          "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
          "valueUrl": "string"
        } ]
      } ],
      "representation": [ "xmlAttr" ],
      "max": "1",
      "id": "Extension.extension:sampleSize.extension:numberOfStudies.id",
      "base": {
        "max": "1",
        "min": 0,
        "path": "Element.id"
      },
      "isSummary": false
    }, {
      "constraint": [ {
        "key": "ele-1",
        "human": "All FHIR elements must have a @value or children",
        "xpath": "@value|f:*|h:div",
        "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1",
        "severity": "error",
        "expression": "hasValue() or (children().count() > id.count())"
      }, {
        "key": "ext-1",
        "human": "Must have either extensions or value[x], not both",
        "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
        "source": "http://hl7.org/fhir/StructureDefinition/Extension|4.0.1",
        "severity": "error",
        "expression": "extension.exists() != value.exists()"
      } ],
      "path": "Extension.extension.extension.extension",
      "min": 0,
      "definition": "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
      "isModifier": false,
      "short": "Additional content defined by implementations",
      "mapping": [ {
        "map": "n/a",
        "identity": "rim"
      } ],
      "slicing": {
        "rules": "open",
        "description": "Extensions are always sliced by (at least) url",
        "discriminator": [ {
          "path": "url",
          "type": "value"
        } ]
      },
      "type": [ {
        "code": "Extension"
      } ],
      "alias": [ "extensions", "user content" ],
      "max": "*",
      "id": "Extension.extension:sampleSize.extension:numberOfStudies.extension",
      "comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
      "base": {
        "max": "*",
        "min": 0,
        "path": "Element.extension"
      },
      "isSummary": false
    }, {
      "path": "Extension.extension.extension.url",
      "min": 1,
      "definition": "Source of the definition for the extension code - a logical name or a URL.",
      "isModifier": false,
      "short": "identifies the meaning of the extension",
      "fixedUri": "numberOfStudies",
      "mapping": [ {
        "map": "N/A",
        "identity": "rim"
      } ],
      "type": [ {
        "code": "http://hl7.org/fhirpath/System.String",
        "extension": [ {
          "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
          "valueUrl": "uri"
        } ]
      } ],
      "representation": [ "xmlAttr" ],
      "max": "1",
      "id": "Extension.extension:sampleSize.extension:numberOfStudies.url",
      "comment": "The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.",
      "base": {
        "max": "1",
        "min": 1,
        "path": "Extension.url"
      },
      "isSummary": false
    }, {
      "constraint": [ {
        "key": "ele-1",
        "human": "All FHIR elements must have a @value or children",
        "xpath": "@value|f:*|h:div",
        "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1",
        "severity": "error",
        "expression": "hasValue() or (children().count() > id.count())"
      } ],
      "path": "Extension.extension.extension.value[x]",
      "min": 0,
      "definition": "Number of participants in the population.",
      "isModifier": false,
      "short": "Number of contributing studies",
      "mapping": [ {
        "map": "N/A",
        "identity": "rim"
      } ],
      "type": [ {
        "code": "unsignedInt"
      } ],
      "max": "1",
      "id": "Extension.extension:sampleSize.extension:numberOfStudies.value[x]",
      "base": {
        "max": "1",
        "min": 0,
        "path": "Extension.value[x]"
      },
      "isSummary": false
    }, {
      "constraint": [ {
        "key": "ele-1",
        "human": "All FHIR elements must have a @value or children",
        "xpath": "@value|f:*|h:div",
        "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1",
        "severity": "error",
        "expression": "hasValue() or (children().count() > id.count())"
      }, {
        "key": "ext-1",
        "human": "Must have either extensions or value[x], not both",
        "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
        "source": "http://hl7.org/fhir/StructureDefinition/Extension|4.0.1",
        "severity": "error",
        "expression": "extension.exists() != value.exists()"
      } ],
      "path": "Extension.extension.extension",
      "requirements": "Element `Evidence.statistic.sampleSize.numberOfParticipants` is part of an existing definition because parent element `Evidence.statistic.sampleSize` requires a cross-version extension.\nElement `Evidence.statistic.sampleSize.numberOfParticipants` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.sampleSize.numberOfParticipants` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
      "min": 0,
      "definition": "R4B: `Evidence.statistic.sampleSize.numberOfParticipants` (new:unsignedInt)",
      "isModifier": false,
      "short": "R4B: Cumulative number of participants (new)",
      "type": [ {
        "code": "Extension"
      } ],
      "sliceName": "numberOfParticipants",
      "max": "1",
      "id": "Extension.extension:sampleSize.extension:numberOfParticipants",
      "comment": "Element `Evidence.statistic.sampleSize.numberOfParticipants` is part of an existing definition because parent element `Evidence.statistic.sampleSize` requires a cross-version extension.\nElement `Evidence.statistic.sampleSize.numberOfParticipants` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.sampleSize.numberOfParticipants` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
      "base": {
        "max": "*",
        "min": 0,
        "path": "Element.extension"
      },
      "isSummary": false
    }, {
      "path": "Extension.extension.extension.id",
      "min": 0,
      "definition": "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
      "isModifier": false,
      "short": "Unique id for inter-element referencing",
      "mapping": [ {
        "map": "n/a",
        "identity": "rim"
      } ],
      "type": [ {
        "code": "http://hl7.org/fhirpath/System.String",
        "extension": [ {
          "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
          "valueUrl": "string"
        } ]
      } ],
      "representation": [ "xmlAttr" ],
      "max": "1",
      "id": "Extension.extension:sampleSize.extension:numberOfParticipants.id",
      "base": {
        "max": "1",
        "min": 0,
        "path": "Element.id"
      },
      "isSummary": false
    }, {
      "constraint": [ {
        "key": "ele-1",
        "human": "All FHIR elements must have a @value or children",
        "xpath": "@value|f:*|h:div",
        "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1",
        "severity": "error",
        "expression": "hasValue() or (children().count() > id.count())"
      }, {
        "key": "ext-1",
        "human": "Must have either extensions or value[x], not both",
        "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
        "source": "http://hl7.org/fhir/StructureDefinition/Extension|4.0.1",
        "severity": "error",
        "expression": "extension.exists() != value.exists()"
      } ],
      "path": "Extension.extension.extension.extension",
      "min": 0,
      "definition": "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
      "isModifier": false,
      "short": "Additional content defined by implementations",
      "mapping": [ {
        "map": "n/a",
        "identity": "rim"
      } ],
      "slicing": {
        "rules": "open",
        "description": "Extensions are always sliced by (at least) url",
        "discriminator": [ {
          "path": "url",
          "type": "value"
        } ]
      },
      "type": [ {
        "code": "Extension"
      } ],
      "alias": [ "extensions", "user content" ],
      "max": "*",
      "id": "Extension.extension:sampleSize.extension:numberOfParticipants.extension",
      "comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
      "base": {
        "max": "*",
        "min": 0,
        "path": "Element.extension"
      },
      "isSummary": false
    }, {
      "path": "Extension.extension.extension.url",
      "min": 1,
      "definition": "Source of the definition for the extension code - a logical name or a URL.",
      "isModifier": false,
      "short": "identifies the meaning of the extension",
      "fixedUri": "numberOfParticipants",
      "mapping": [ {
        "map": "N/A",
        "identity": "rim"
      } ],
      "type": [ {
        "code": "http://hl7.org/fhirpath/System.String",
        "extension": [ {
          "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
          "valueUrl": "uri"
        } ]
      } ],
      "representation": [ "xmlAttr" ],
      "max": "1",
      "id": "Extension.extension:sampleSize.extension:numberOfParticipants.url",
      "comment": "The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.",
      "base": {
        "max": "1",
        "min": 1,
        "path": "Extension.url"
      },
      "isSummary": false
    }, {
      "constraint": [ {
        "key": "ele-1",
        "human": "All FHIR elements must have a @value or children",
        "xpath": "@value|f:*|h:div",
        "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1",
        "severity": "error",
        "expression": "hasValue() or (children().count() > id.count())"
      } ],
      "path": "Extension.extension.extension.value[x]",
      "min": 0,
      "definition": "A human-readable string to clarify or explain concepts about the sample size.",
      "isModifier": false,
      "short": "Cumulative number of participants",
      "mapping": [ {
        "map": "N/A",
        "identity": "rim"
      } ],
      "type": [ {
        "code": "unsignedInt"
      } ],
      "max": "1",
      "id": "Extension.extension:sampleSize.extension:numberOfParticipants.value[x]",
      "base": {
        "max": "1",
        "min": 0,
        "path": "Extension.value[x]"
      },
      "isSummary": false
    }, {
      "constraint": [ {
        "key": "ele-1",
        "human": "All FHIR elements must have a @value or children",
        "xpath": "@value|f:*|h:div",
        "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1",
        "severity": "error",
        "expression": "hasValue() or (children().count() > id.count())"
      }, {
        "key": "ext-1",
        "human": "Must have either extensions or value[x], not both",
        "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
        "source": "http://hl7.org/fhir/StructureDefinition/Extension|4.0.1",
        "severity": "error",
        "expression": "extension.exists() != value.exists()"
      } ],
      "path": "Extension.extension.extension",
      "requirements": "Element `Evidence.statistic.sampleSize.knownDataCount` is part of an existing definition because parent element `Evidence.statistic.sampleSize` requires a cross-version extension.\nElement `Evidence.statistic.sampleSize.knownDataCount` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.sampleSize.knownDataCount` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
      "min": 0,
      "definition": "R4B: `Evidence.statistic.sampleSize.knownDataCount` (new:unsignedInt)",
      "isModifier": false,
      "short": "R4B: Number of participants with known results for measured variables (new)",
      "type": [ {
        "code": "Extension"
      } ],
      "sliceName": "knownDataCount",
      "max": "1",
      "id": "Extension.extension:sampleSize.extension:knownDataCount",
      "comment": "Element `Evidence.statistic.sampleSize.knownDataCount` is part of an existing definition because parent element `Evidence.statistic.sampleSize` requires a cross-version extension.\nElement `Evidence.statistic.sampleSize.knownDataCount` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.sampleSize.knownDataCount` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
      "base": {
        "max": "*",
        "min": 0,
        "path": "Element.extension"
      },
      "isSummary": false
    }, {
      "path": "Extension.extension.extension.id",
      "min": 0,
      "definition": "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
      "isModifier": false,
      "short": "Unique id for inter-element referencing",
      "mapping": [ {
        "map": "n/a",
        "identity": "rim"
      } ],
      "type": [ {
        "code": "http://hl7.org/fhirpath/System.String",
        "extension": [ {
          "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
          "valueUrl": "string"
        } ]
      } ],
      "representation": [ "xmlAttr" ],
      "max": "1",
      "id": "Extension.extension:sampleSize.extension:knownDataCount.id",
      "base": {
        "max": "1",
        "min": 0,
        "path": "Element.id"
      },
      "isSummary": false
    }, {
      "constraint": [ {
        "key": "ele-1",
        "human": "All FHIR elements must have a @value or children",
        "xpath": "@value|f:*|h:div",
        "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1",
        "severity": "error",
        "expression": "hasValue() or (children().count() > id.count())"
      }, {
        "key": "ext-1",
        "human": "Must have either extensions or value[x], not both",
        "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
        "source": "http://hl7.org/fhir/StructureDefinition/Extension|4.0.1",
        "severity": "error",
        "expression": "extension.exists() != value.exists()"
      } ],
      "path": "Extension.extension.extension.extension",
      "min": 0,
      "definition": "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
      "isModifier": false,
      "short": "Additional content defined by implementations",
      "mapping": [ {
        "map": "n/a",
        "identity": "rim"
      } ],
      "slicing": {
        "rules": "open",
        "description": "Extensions are always sliced by (at least) url",
        "discriminator": [ {
          "path": "url",
          "type": "value"
        } ]
      },
      "type": [ {
        "code": "Extension"
      } ],
      "alias": [ "extensions", "user content" ],
      "max": "*",
      "id": "Extension.extension:sampleSize.extension:knownDataCount.extension",
      "comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
      "base": {
        "max": "*",
        "min": 0,
        "path": "Element.extension"
      },
      "isSummary": false
    }, {
      "path": "Extension.extension.extension.url",
      "min": 1,
      "definition": "Source of the definition for the extension code - a logical name or a URL.",
      "isModifier": false,
      "short": "identifies the meaning of the extension",
      "fixedUri": "knownDataCount",
      "mapping": [ {
        "map": "N/A",
        "identity": "rim"
      } ],
      "type": [ {
        "code": "http://hl7.org/fhirpath/System.String",
        "extension": [ {
          "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
          "valueUrl": "uri"
        } ]
      } ],
      "representation": [ "xmlAttr" ],
      "max": "1",
      "id": "Extension.extension:sampleSize.extension:knownDataCount.url",
      "comment": "The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.",
      "base": {
        "max": "1",
        "min": 1,
        "path": "Extension.url"
      },
      "isSummary": false
    }, {
      "constraint": [ {
        "key": "ele-1",
        "human": "All FHIR elements must have a @value or children",
        "xpath": "@value|f:*|h:div",
        "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1",
        "severity": "error",
        "expression": "hasValue() or (children().count() > id.count())"
      } ],
      "path": "Extension.extension.extension.value[x]",
      "min": 0,
      "definition": "Number of participants with known results for measured variables.",
      "isModifier": false,
      "short": "Number of participants with known results for measured variables",
      "mapping": [ {
        "map": "N/A",
        "identity": "rim"
      } ],
      "type": [ {
        "code": "unsignedInt"
      } ],
      "max": "1",
      "id": "Extension.extension:sampleSize.extension:knownDataCount.value[x]",
      "base": {
        "max": "1",
        "min": 0,
        "path": "Extension.value[x]"
      },
      "isSummary": false
    }, {
      "path": "Extension.extension.url",
      "min": 1,
      "definition": "Source of the definition for the extension code - a logical name or a URL.",
      "isModifier": false,
      "short": "identifies the meaning of the extension",
      "fixedUri": "sampleSize",
      "mapping": [ {
        "map": "N/A",
        "identity": "rim"
      } ],
      "type": [ {
        "code": "http://hl7.org/fhirpath/System.String",
        "extension": [ {
          "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
          "valueUrl": "uri"
        } ]
      } ],
      "representation": [ "xmlAttr" ],
      "max": "1",
      "id": "Extension.extension:sampleSize.url",
      "comment": "The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.",
      "base": {
        "max": "1",
        "min": 1,
        "path": "Extension.url"
      },
      "isSummary": false
    }, {
      "constraint": [ {
        "key": "ele-1",
        "human": "All FHIR elements must have a @value or children",
        "xpath": "@value|f:*|h:div",
        "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1",
        "severity": "error",
        "expression": "hasValue() or (children().count() > id.count())"
      } ],
      "path": "Extension.extension.value[x]",
      "min": 0,
      "definition": "Value of extension - must be one of a constrained set of the data types (see [Extensibility](http://hl7.org/fhir/R4/extensibility.html) for a list).",
      "isModifier": false,
      "short": "Value of extension",
      "mapping": [ {
        "map": "N/A",
        "identity": "rim"
      } ],
      "type": [ {
        "code": "base64Binary"
      }, {
        "code": "boolean"
      }, {
        "code": "canonical"
      }, {
        "code": "code"
      }, {
        "code": "date"
      }, {
        "code": "dateTime"
      }, {
        "code": "decimal"
      }, {
        "code": "id"
      }, {
        "code": "instant"
      }, {
        "code": "integer"
      }, {
        "code": "markdown"
      }, {
        "code": "oid"
      }, {
        "code": "positiveInt"
      }, {
        "code": "string"
      }, {
        "code": "time"
      }, {
        "code": "unsignedInt"
      }, {
        "code": "uri"
      }, {
        "code": "url"
      }, {
        "code": "uuid"
      }, {
        "code": "Address"
      }, {
        "code": "Age"
      }, {
        "code": "Annotation"
      }, {
        "code": "Attachment"
      }, {
        "code": "CodeableConcept"
      }, {
        "code": "Coding"
      }, {
        "code": "ContactPoint"
      }, {
        "code": "Count"
      }, {
        "code": "Distance"
      }, {
        "code": "Duration"
      }, {
        "code": "HumanName"
      }, {
        "code": "Identifier"
      }, {
        "code": "Money"
      }, {
        "code": "Period"
      }, {
        "code": "Quantity"
      }, {
        "code": "Range"
      }, {
        "code": "Ratio"
      }, {
        "code": "Reference"
      }, {
        "code": "SampledData"
      }, {
        "code": "Signature"
      }, {
        "code": "Timing"
      }, {
        "code": "ContactDetail"
      }, {
        "code": "Contributor"
      }, {
        "code": "DataRequirement"
      }, {
        "code": "Expression"
      }, {
        "code": "ParameterDefinition"
      }, {
        "code": "RelatedArtifact"
      }, {
        "code": "TriggerDefinition"
      }, {
        "code": "UsageContext"
      }, {
        "code": "Dosage"
      }, {
        "code": "Meta"
      } ],
      "max": "0",
      "id": "Extension.extension:sampleSize.value[x]",
      "base": {
        "max": "1",
        "min": 0,
        "path": "Extension.value[x]"
      },
      "isSummary": false
    }, {
      "constraint": [ {
        "key": "ele-1",
        "human": "All FHIR elements must have a @value or children",
        "xpath": "@value|f:*|h:div",
        "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1",
        "severity": "error",
        "expression": "hasValue() or (children().count() > id.count())"
      }, {
        "key": "ext-1",
        "human": "Must have either extensions or value[x], not both",
        "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
        "source": "http://hl7.org/fhir/StructureDefinition/Extension|4.0.1",
        "severity": "error",
        "expression": "extension.exists() != value.exists()"
      } ],
      "path": "Extension.extension",
      "requirements": "Element `Evidence.statistic.attributeEstimate` is part of an existing definition because parent element `Evidence.statistic` requires a cross-version extension.\nElement `Evidence.statistic.attributeEstimate` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.attributeEstimate` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).\nCreating extension because element `Evidence.statistic.attributeEstimate` is a content reference and requires an extesion definition.",
      "min": 0,
      "definition": "R4B: `Evidence.statistic.attributeEstimate` (new:BackboneElement)",
      "isModifier": false,
      "short": "R4B: An attribute of the Statistic (new)",
      "type": [ {
        "code": "Extension"
      } ],
      "sliceName": "attributeEstimate",
      "max": "*",
      "id": "Extension.extension:attributeEstimate",
      "comment": "Element `Evidence.statistic.attributeEstimate` is part of an existing definition because parent element `Evidence.statistic` requires a cross-version extension.\nElement `Evidence.statistic.attributeEstimate` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.attributeEstimate` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
      "base": {
        "max": "*",
        "min": 0,
        "path": "Element.extension"
      },
      "isSummary": false
    }, {
      "path": "Extension.extension.id",
      "min": 0,
      "definition": "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
      "isModifier": false,
      "short": "Unique id for inter-element referencing",
      "mapping": [ {
        "map": "n/a",
        "identity": "rim"
      } ],
      "type": [ {
        "code": "http://hl7.org/fhirpath/System.String",
        "extension": [ {
          "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
          "valueUrl": "string"
        } ]
      } ],
      "representation": [ "xmlAttr" ],
      "max": "1",
      "id": "Extension.extension:attributeEstimate.id",
      "base": {
        "max": "1",
        "min": 0,
        "path": "Element.id"
      },
      "isSummary": false
    }, {
      "constraint": [ {
        "key": "ele-1",
        "human": "All FHIR elements must have a @value or children",
        "xpath": "@value|f:*|h:div",
        "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1",
        "severity": "error",
        "expression": "hasValue() or (children().count() > id.count())"
      }, {
        "key": "ext-1",
        "human": "Must have either extensions or value[x], not both",
        "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
        "source": "http://hl7.org/fhir/StructureDefinition/Extension|4.0.1",
        "severity": "error",
        "expression": "extension.exists() != value.exists()"
      } ],
      "path": "Extension.extension.extension",
      "min": 0,
      "definition": "An Extension",
      "isModifier": false,
      "short": "Extension",
      "slicing": {
        "rules": "open",
        "ordered": false,
        "description": "Extensions are always sliced by (at least) url",
        "discriminator": [ {
          "path": "url",
          "type": "value"
        } ]
      },
      "type": [ {
        "code": "Extension"
      } ],
      "max": "*",
      "id": "Extension.extension:attributeEstimate.extension",
      "base": {
        "max": "*",
        "min": 0,
        "path": "Element.extension"
      },
      "isSummary": false
    }, {
      "constraint": [ {
        "key": "ele-1",
        "human": "All FHIR elements must have a @value or children",
        "xpath": "@value|f:*|h:div",
        "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1",
        "severity": "error",
        "expression": "hasValue() or (children().count() > id.count())"
      }, {
        "key": "ext-1",
        "human": "Must have either extensions or value[x], not both",
        "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
        "source": "http://hl7.org/fhir/StructureDefinition/Extension|4.0.1",
        "severity": "error",
        "expression": "extension.exists() != value.exists()"
      } ],
      "path": "Extension.extension.extension",
      "requirements": "Element `Evidence.statistic.attributeEstimate.description` is part of an existing definition because parent element `Evidence.statistic.attributeEstimate` requires a cross-version extension.\nElement `Evidence.statistic.attributeEstimate.description` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.attributeEstimate.description` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
      "min": 0,
      "definition": "R4B: `Evidence.statistic.attributeEstimate.description` (new:string)",
      "isModifier": false,
      "short": "R4B: Textual description of the attribute estimate (new)",
      "type": [ {
        "code": "Extension"
      } ],
      "sliceName": "description",
      "max": "1",
      "id": "Extension.extension:attributeEstimate.extension:description",
      "comment": "Element `Evidence.statistic.attributeEstimate.description` is part of an existing definition because parent element `Evidence.statistic.attributeEstimate` requires a cross-version extension.\nElement `Evidence.statistic.attributeEstimate.description` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.attributeEstimate.description` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
      "base": {
        "max": "*",
        "min": 0,
        "path": "Element.extension"
      },
      "isSummary": false
    }, {
      "path": "Extension.extension.extension.id",
      "min": 0,
      "definition": "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
      "isModifier": false,
      "short": "Unique id for inter-element referencing",
      "mapping": [ {
        "map": "n/a",
        "identity": "rim"
      } ],
      "type": [ {
        "code": "http://hl7.org/fhirpath/System.String",
        "extension": [ {
          "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
          "valueUrl": "string"
        } ]
      } ],
      "representation": [ "xmlAttr" ],
      "max": "1",
      "id": "Extension.extension:attributeEstimate.extension:description.id",
      "base": {
        "max": "1",
        "min": 0,
        "path": "Element.id"
      },
      "isSummary": false
    }, {
      "constraint": [ {
        "key": "ele-1",
        "human": "All FHIR elements must have a @value or children",
        "xpath": "@value|f:*|h:div",
        "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1",
        "severity": "error",
        "expression": "hasValue() or (children().count() > id.count())"
      }, {
        "key": "ext-1",
        "human": "Must have either extensions or value[x], not both",
        "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
        "source": "http://hl7.org/fhir/StructureDefinition/Extension|4.0.1",
        "severity": "error",
        "expression": "extension.exists() != value.exists()"
      } ],
      "path": "Extension.extension.extension.extension",
      "min": 0,
      "definition": "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
      "isModifier": false,
      "short": "Additional content defined by implementations",
      "mapping": [ {
        "map": "n/a",
        "identity": "rim"
      } ],
      "slicing": {
        "rules": "open",
        "description": "Extensions are always sliced by (at least) url",
        "discriminator": [ {
          "path": "url",
          "type": "value"
        } ]
      },
      "type": [ {
        "code": "Extension"
      } ],
      "alias": [ "extensions", "user content" ],
      "max": "*",
      "id": "Extension.extension:attributeEstimate.extension:description.extension",
      "comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
      "base": {
        "max": "*",
        "min": 0,
        "path": "Element.extension"
      },
      "isSummary": false
    }, {
      "path": "Extension.extension.extension.url",
      "min": 1,
      "definition": "Source of the definition for the extension code - a logical name or a URL.",
      "isModifier": false,
      "short": "identifies the meaning of the extension",
      "fixedUri": "description",
      "mapping": [ {
        "map": "N/A",
        "identity": "rim"
      } ],
      "type": [ {
        "code": "http://hl7.org/fhirpath/System.String",
        "extension": [ {
          "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
          "valueUrl": "uri"
        } ]
      } ],
      "representation": [ "xmlAttr" ],
      "max": "1",
      "id": "Extension.extension:attributeEstimate.extension:description.url",
      "comment": "The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.",
      "base": {
        "max": "1",
        "min": 1,
        "path": "Extension.url"
      },
      "isSummary": false
    }, {
      "constraint": [ {
        "key": "ele-1",
        "human": "All FHIR elements must have a @value or children",
        "xpath": "@value|f:*|h:div",
        "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1",
        "severity": "error",
        "expression": "hasValue() or (children().count() > id.count())"
      } ],
      "path": "Extension.extension.extension.value[x]",
      "min": 0,
      "definition": "Human-readable summary of the estimate.",
      "isModifier": false,
      "short": "Textual description of the attribute estimate",
      "mapping": [ {
        "map": "N/A",
        "identity": "rim"
      } ],
      "type": [ {
        "code": "string"
      } ],
      "max": "1",
      "id": "Extension.extension:attributeEstimate.extension:description.value[x]",
      "base": {
        "max": "1",
        "min": 0,
        "path": "Extension.value[x]"
      },
      "isSummary": false
    }, {
      "constraint": [ {
        "key": "ele-1",
        "human": "All FHIR elements must have a @value or children",
        "xpath": "@value|f:*|h:div",
        "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1",
        "severity": "error",
        "expression": "hasValue() or (children().count() > id.count())"
      }, {
        "key": "ext-1",
        "human": "Must have either extensions or value[x], not both",
        "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
        "source": "http://hl7.org/fhir/StructureDefinition/Extension|4.0.1",
        "severity": "error",
        "expression": "extension.exists() != value.exists()"
      } ],
      "path": "Extension.extension.extension",
      "requirements": "Element `Evidence.statistic.attributeEstimate.note` is part of an existing definition because parent element `Evidence.statistic.attributeEstimate` requires a cross-version extension.\nElement `Evidence.statistic.attributeEstimate.note` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.attributeEstimate.note` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
      "min": 0,
      "definition": "R4B: `Evidence.statistic.attributeEstimate.note` (new:Annotation)",
      "isModifier": false,
      "short": "R4B: Footnote or explanatory note about the estimate (new)",
      "type": [ {
        "code": "Extension"
      } ],
      "sliceName": "note",
      "max": "*",
      "id": "Extension.extension:attributeEstimate.extension:note",
      "comment": "Element `Evidence.statistic.attributeEstimate.note` is part of an existing definition because parent element `Evidence.statistic.attributeEstimate` requires a cross-version extension.\nElement `Evidence.statistic.attributeEstimate.note` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.attributeEstimate.note` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
      "base": {
        "max": "*",
        "min": 0,
        "path": "Element.extension"
      },
      "isSummary": false
    }, {
      "path": "Extension.extension.extension.id",
      "min": 0,
      "definition": "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
      "isModifier": false,
      "short": "Unique id for inter-element referencing",
      "mapping": [ {
        "map": "n/a",
        "identity": "rim"
      } ],
      "type": [ {
        "code": "http://hl7.org/fhirpath/System.String",
        "extension": [ {
          "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
          "valueUrl": "string"
        } ]
      } ],
      "representation": [ "xmlAttr" ],
      "max": "1",
      "id": "Extension.extension:attributeEstimate.extension:note.id",
      "base": {
        "max": "1",
        "min": 0,
        "path": "Element.id"
      },
      "isSummary": false
    }, {
      "constraint": [ {
        "key": "ele-1",
        "human": "All FHIR elements must have a @value or children",
        "xpath": "@value|f:*|h:div",
        "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1",
        "severity": "error",
        "expression": "hasValue() or (children().count() > id.count())"
      }, {
        "key": "ext-1",
        "human": "Must have either extensions or value[x], not both",
        "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
        "source": "http://hl7.org/fhir/StructureDefinition/Extension|4.0.1",
        "severity": "error",
        "expression": "extension.exists() != value.exists()"
      } ],
      "path": "Extension.extension.extension.extension",
      "min": 0,
      "definition": "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
      "isModifier": false,
      "short": "Additional content defined by implementations",
      "mapping": [ {
        "map": "n/a",
        "identity": "rim"
      } ],
      "slicing": {
        "rules": "open",
        "description": "Extensions are always sliced by (at least) url",
        "discriminator": [ {
          "path": "url",
          "type": "value"
        } ]
      },
      "type": [ {
        "code": "Extension"
      } ],
      "alias": [ "extensions", "user content" ],
      "max": "*",
      "id": "Extension.extension:attributeEstimate.extension:note.extension",
      "comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
      "base": {
        "max": "*",
        "min": 0,
        "path": "Element.extension"
      },
      "isSummary": false
    }, {
      "path": "Extension.extension.extension.url",
      "min": 1,
      "definition": "Source of the definition for the extension code - a logical name or a URL.",
      "isModifier": false,
      "short": "identifies the meaning of the extension",
      "fixedUri": "note",
      "mapping": [ {
        "map": "N/A",
        "identity": "rim"
      } ],
      "type": [ {
        "code": "http://hl7.org/fhirpath/System.String",
        "extension": [ {
          "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
          "valueUrl": "uri"
        } ]
      } ],
      "representation": [ "xmlAttr" ],
      "max": "1",
      "id": "Extension.extension:attributeEstimate.extension:note.url",
      "comment": "The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.",
      "base": {
        "max": "1",
        "min": 1,
        "path": "Extension.url"
      },
      "isSummary": false
    }, {
      "constraint": [ {
        "key": "ele-1",
        "human": "All FHIR elements must have a @value or children",
        "xpath": "@value|f:*|h:div",
        "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1",
        "severity": "error",
        "expression": "hasValue() or (children().count() > id.count())"
      } ],
      "path": "Extension.extension.extension.value[x]",
      "min": 0,
      "definition": "Footnote or explanatory note about the estimate.",
      "isModifier": false,
      "short": "Footnote or explanatory note about the estimate",
      "mapping": [ {
        "map": "N/A",
        "identity": "rim"
      } ],
      "type": [ {
        "code": "Annotation"
      } ],
      "max": "1",
      "id": "Extension.extension:attributeEstimate.extension:note.value[x]",
      "base": {
        "max": "1",
        "min": 0,
        "path": "Extension.value[x]"
      },
      "isSummary": false
    }, {
      "constraint": [ {
        "key": "ele-1",
        "human": "All FHIR elements must have a @value or children",
        "xpath": "@value|f:*|h:div",
        "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1",
        "severity": "error",
        "expression": "hasValue() or (children().count() > id.count())"
      }, {
        "key": "ext-1",
        "human": "Must have either extensions or value[x], not both",
        "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
        "source": "http://hl7.org/fhir/StructureDefinition/Extension|4.0.1",
        "severity": "error",
        "expression": "extension.exists() != value.exists()"
      } ],
      "path": "Extension.extension.extension",
      "requirements": "Element `Evidence.statistic.attributeEstimate.type` is part of an existing definition because parent element `Evidence.statistic.attributeEstimate` requires a cross-version extension.\nElement `Evidence.statistic.attributeEstimate.type` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.attributeEstimate.type` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
      "min": 0,
      "definition": "R4B: `Evidence.statistic.attributeEstimate.type` (new:CodeableConcept)",
      "isModifier": false,
      "short": "R4B: The type of attribute estimate, eg confidence interval or p value (new)",
      "type": [ {
        "code": "Extension"
      } ],
      "sliceName": "type",
      "max": "1",
      "id": "Extension.extension:attributeEstimate.extension:type",
      "comment": "Element `Evidence.statistic.attributeEstimate.type` is part of an existing definition because parent element `Evidence.statistic.attributeEstimate` requires a cross-version extension.\nElement `Evidence.statistic.attributeEstimate.type` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.attributeEstimate.type` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
      "base": {
        "max": "*",
        "min": 0,
        "path": "Element.extension"
      },
      "isSummary": false
    }, {
      "path": "Extension.extension.extension.id",
      "min": 0,
      "definition": "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
      "isModifier": false,
      "short": "Unique id for inter-element referencing",
      "mapping": [ {
        "map": "n/a",
        "identity": "rim"
      } ],
      "type": [ {
        "code": "http://hl7.org/fhirpath/System.String",
        "extension": [ {
          "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
          "valueUrl": "string"
        } ]
      } ],
      "representation": [ "xmlAttr" ],
      "max": "1",
      "id": "Extension.extension:attributeEstimate.extension:type.id",
      "base": {
        "max": "1",
        "min": 0,
        "path": "Element.id"
      },
      "isSummary": false
    }, {
      "constraint": [ {
        "key": "ele-1",
        "human": "All FHIR elements must have a @value or children",
        "xpath": "@value|f:*|h:div",
        "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1",
        "severity": "error",
        "expression": "hasValue() or (children().count() > id.count())"
      }, {
        "key": "ext-1",
        "human": "Must have either extensions or value[x], not both",
        "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
        "source": "http://hl7.org/fhir/StructureDefinition/Extension|4.0.1",
        "severity": "error",
        "expression": "extension.exists() != value.exists()"
      } ],
      "path": "Extension.extension.extension.extension",
      "min": 0,
      "definition": "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
      "isModifier": false,
      "short": "Additional content defined by implementations",
      "mapping": [ {
        "map": "n/a",
        "identity": "rim"
      } ],
      "slicing": {
        "rules": "open",
        "description": "Extensions are always sliced by (at least) url",
        "discriminator": [ {
          "path": "url",
          "type": "value"
        } ]
      },
      "type": [ {
        "code": "Extension"
      } ],
      "alias": [ "extensions", "user content" ],
      "max": "*",
      "id": "Extension.extension:attributeEstimate.extension:type.extension",
      "comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
      "base": {
        "max": "*",
        "min": 0,
        "path": "Element.extension"
      },
      "isSummary": false
    }, {
      "path": "Extension.extension.extension.url",
      "min": 1,
      "definition": "Source of the definition for the extension code - a logical name or a URL.",
      "isModifier": false,
      "short": "identifies the meaning of the extension",
      "fixedUri": "type",
      "mapping": [ {
        "map": "N/A",
        "identity": "rim"
      } ],
      "type": [ {
        "code": "http://hl7.org/fhirpath/System.String",
        "extension": [ {
          "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
          "valueUrl": "uri"
        } ]
      } ],
      "representation": [ "xmlAttr" ],
      "max": "1",
      "id": "Extension.extension:attributeEstimate.extension:type.url",
      "comment": "The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.",
      "base": {
        "max": "1",
        "min": 1,
        "path": "Extension.url"
      },
      "isSummary": false
    }, {
      "constraint": [ {
        "key": "ele-1",
        "human": "All FHIR elements must have a @value or children",
        "xpath": "@value|f:*|h:div",
        "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1",
        "severity": "error",
        "expression": "hasValue() or (children().count() > id.count())"
      } ],
      "path": "Extension.extension.extension.value[x]",
      "min": 0,
      "definition": "The type of attribute estimate, eg confidence interval or p value.",
      "isModifier": false,
      "short": "The type of attribute estimate, eg confidence interval or p value",
      "mapping": [ {
        "map": "N/A",
        "identity": "rim"
      } ],
      "type": [ {
        "code": "CodeableConcept"
      } ],
      "binding": {
        "strength": "extensible",
        "valueSet": "http://hl7.org/fhir/uv/xver/ValueSet/R4B-attribute-estimate-type-for-R4|0.1.0"
      },
      "max": "1",
      "id": "Extension.extension:attributeEstimate.extension:type.value[x]",
      "base": {
        "max": "1",
        "min": 0,
        "path": "Extension.value[x]"
      },
      "isSummary": false
    }, {
      "constraint": [ {
        "key": "ele-1",
        "human": "All FHIR elements must have a @value or children",
        "xpath": "@value|f:*|h:div",
        "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1",
        "severity": "error",
        "expression": "hasValue() or (children().count() > id.count())"
      }, {
        "key": "ext-1",
        "human": "Must have either extensions or value[x], not both",
        "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
        "source": "http://hl7.org/fhir/StructureDefinition/Extension|4.0.1",
        "severity": "error",
        "expression": "extension.exists() != value.exists()"
      } ],
      "path": "Extension.extension.extension",
      "requirements": "Element `Evidence.statistic.attributeEstimate.quantity` is part of an existing definition because parent element `Evidence.statistic.attributeEstimate` requires a cross-version extension.\nElement `Evidence.statistic.attributeEstimate.quantity` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.attributeEstimate.quantity` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
      "min": 0,
      "definition": "R4B: `Evidence.statistic.attributeEstimate.quantity` (new:Quantity)",
      "isModifier": false,
      "short": "R4B: The singular quantity of the attribute estimate, for attribute estimates represented as single values; also used to report unit of measure (new)",
      "type": [ {
        "code": "Extension"
      } ],
      "sliceName": "quantity",
      "max": "1",
      "id": "Extension.extension:attributeEstimate.extension:quantity",
      "comment": "Element `Evidence.statistic.attributeEstimate.quantity` is part of an existing definition because parent element `Evidence.statistic.attributeEstimate` requires a cross-version extension.\nElement `Evidence.statistic.attributeEstimate.quantity` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.attributeEstimate.quantity` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).\nOften the p value",
      "base": {
        "max": "*",
        "min": 0,
        "path": "Element.extension"
      },
      "isSummary": false
    }, {
      "path": "Extension.extension.extension.id",
      "min": 0,
      "definition": "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
      "isModifier": false,
      "short": "Unique id for inter-element referencing",
      "mapping": [ {
        "map": "n/a",
        "identity": "rim"
      } ],
      "type": [ {
        "code": "http://hl7.org/fhirpath/System.String",
        "extension": [ {
          "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
          "valueUrl": "string"
        } ]
      } ],
      "representation": [ "xmlAttr" ],
      "max": "1",
      "id": "Extension.extension:attributeEstimate.extension:quantity.id",
      "base": {
        "max": "1",
        "min": 0,
        "path": "Element.id"
      },
      "isSummary": false
    }, {
      "constraint": [ {
        "key": "ele-1",
        "human": "All FHIR elements must have a @value or children",
        "xpath": "@value|f:*|h:div",
        "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1",
        "severity": "error",
        "expression": "hasValue() or (children().count() > id.count())"
      }, {
        "key": "ext-1",
        "human": "Must have either extensions or value[x], not both",
        "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
        "source": "http://hl7.org/fhir/StructureDefinition/Extension|4.0.1",
        "severity": "error",
        "expression": "extension.exists() != value.exists()"
      } ],
      "path": "Extension.extension.extension.extension",
      "min": 0,
      "definition": "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
      "isModifier": false,
      "short": "Additional content defined by implementations",
      "mapping": [ {
        "map": "n/a",
        "identity": "rim"
      } ],
      "slicing": {
        "rules": "open",
        "description": "Extensions are always sliced by (at least) url",
        "discriminator": [ {
          "path": "url",
          "type": "value"
        } ]
      },
      "type": [ {
        "code": "Extension"
      } ],
      "alias": [ "extensions", "user content" ],
      "max": "*",
      "id": "Extension.extension:attributeEstimate.extension:quantity.extension",
      "comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
      "base": {
        "max": "*",
        "min": 0,
        "path": "Element.extension"
      },
      "isSummary": false
    }, {
      "path": "Extension.extension.extension.url",
      "min": 1,
      "definition": "Source of the definition for the extension code - a logical name or a URL.",
      "isModifier": false,
      "short": "identifies the meaning of the extension",
      "fixedUri": "quantity",
      "mapping": [ {
        "map": "N/A",
        "identity": "rim"
      } ],
      "type": [ {
        "code": "http://hl7.org/fhirpath/System.String",
        "extension": [ {
          "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
          "valueUrl": "uri"
        } ]
      } ],
      "representation": [ "xmlAttr" ],
      "max": "1",
      "id": "Extension.extension:attributeEstimate.extension:quantity.url",
      "comment": "The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.",
      "base": {
        "max": "1",
        "min": 1,
        "path": "Extension.url"
      },
      "isSummary": false
    }, {
      "constraint": [ {
        "key": "ele-1",
        "human": "All FHIR elements must have a @value or children",
        "xpath": "@value|f:*|h:div",
        "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1",
        "severity": "error",
        "expression": "hasValue() or (children().count() > id.count())"
      } ],
      "path": "Extension.extension.extension.value[x]",
      "min": 0,
      "definition": "The singular quantity of the attribute estimate, for attribute estimates represented as single values; also used to report unit of measure.",
      "isModifier": false,
      "short": "The singular quantity of the attribute estimate, for attribute estimates represented as single values; also used to report unit of measure",
      "mapping": [ {
        "map": "N/A",
        "identity": "rim"
      } ],
      "type": [ {
        "code": "Quantity"
      } ],
      "max": "1",
      "id": "Extension.extension:attributeEstimate.extension:quantity.value[x]",
      "comment": "Often the p value",
      "base": {
        "max": "1",
        "min": 0,
        "path": "Extension.value[x]"
      },
      "isSummary": false
    }, {
      "constraint": [ {
        "key": "ele-1",
        "human": "All FHIR elements must have a @value or children",
        "xpath": "@value|f:*|h:div",
        "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1",
        "severity": "error",
        "expression": "hasValue() or (children().count() > id.count())"
      }, {
        "key": "ext-1",
        "human": "Must have either extensions or value[x], not both",
        "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
        "source": "http://hl7.org/fhir/StructureDefinition/Extension|4.0.1",
        "severity": "error",
        "expression": "extension.exists() != value.exists()"
      } ],
      "path": "Extension.extension.extension",
      "requirements": "Element `Evidence.statistic.attributeEstimate.level` is part of an existing definition because parent element `Evidence.statistic.attributeEstimate` requires a cross-version extension.\nElement `Evidence.statistic.attributeEstimate.level` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.attributeEstimate.level` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
      "min": 0,
      "definition": "R4B: `Evidence.statistic.attributeEstimate.level` (new:decimal)",
      "isModifier": false,
      "short": "R4B: Level of confidence interval, eg 0.95 for 95% confidence interval (new)",
      "type": [ {
        "code": "Extension"
      } ],
      "sliceName": "level",
      "max": "1",
      "id": "Extension.extension:attributeEstimate.extension:level",
      "comment": "Element `Evidence.statistic.attributeEstimate.level` is part of an existing definition because parent element `Evidence.statistic.attributeEstimate` requires a cross-version extension.\nElement `Evidence.statistic.attributeEstimate.level` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.attributeEstimate.level` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
      "base": {
        "max": "*",
        "min": 0,
        "path": "Element.extension"
      },
      "isSummary": false
    }, {
      "path": "Extension.extension.extension.id",
      "min": 0,
      "definition": "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
      "isModifier": false,
      "short": "Unique id for inter-element referencing",
      "mapping": [ {
        "map": "n/a",
        "identity": "rim"
      } ],
      "type": [ {
        "code": "http://hl7.org/fhirpath/System.String",
        "extension": [ {
          "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
          "valueUrl": "string"
        } ]
      } ],
      "representation": [ "xmlAttr" ],
      "max": "1",
      "id": "Extension.extension:attributeEstimate.extension:level.id",
      "base": {
        "max": "1",
        "min": 0,
        "path": "Element.id"
      },
      "isSummary": false
    }, {
      "constraint": [ {
        "key": "ele-1",
        "human": "All FHIR elements must have a @value or children",
        "xpath": "@value|f:*|h:div",
        "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1",
        "severity": "error",
        "expression": "hasValue() or (children().count() > id.count())"
      }, {
        "key": "ext-1",
        "human": "Must have either extensions or value[x], not both",
        "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
        "source": "http://hl7.org/fhir/StructureDefinition/Extension|4.0.1",
        "severity": "error",
        "expression": "extension.exists() != value.exists()"
      } ],
      "path": "Extension.extension.extension.extension",
      "min": 0,
      "definition": "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
      "isModifier": false,
      "short": "Additional content defined by implementations",
      "mapping": [ {
        "map": "n/a",
        "identity": "rim"
      } ],
      "slicing": {
        "rules": "open",
        "description": "Extensions are always sliced by (at least) url",
        "discriminator": [ {
          "path": "url",
          "type": "value"
        } ]
      },
      "type": [ {
        "code": "Extension"
      } ],
      "alias": [ "extensions", "user content" ],
      "max": "*",
      "id": "Extension.extension:attributeEstimate.extension:level.extension",
      "comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
      "base": {
        "max": "*",
        "min": 0,
        "path": "Element.extension"
      },
      "isSummary": false
    }, {
      "path": "Extension.extension.extension.url",
      "min": 1,
      "definition": "Source of the definition for the extension code - a logical name or a URL.",
      "isModifier": false,
      "short": "identifies the meaning of the extension",
      "fixedUri": "level",
      "mapping": [ {
        "map": "N/A",
        "identity": "rim"
      } ],
      "type": [ {
        "code": "http://hl7.org/fhirpath/System.String",
        "extension": [ {
          "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
          "valueUrl": "uri"
        } ]
      } ],
      "representation": [ "xmlAttr" ],
      "max": "1",
      "id": "Extension.extension:attributeEstimate.extension:level.url",
      "comment": "The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.",
      "base": {
        "max": "1",
        "min": 1,
        "path": "Extension.url"
      },
      "isSummary": false
    }, {
      "constraint": [ {
        "key": "ele-1",
        "human": "All FHIR elements must have a @value or children",
        "xpath": "@value|f:*|h:div",
        "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1",
        "severity": "error",
        "expression": "hasValue() or (children().count() > id.count())"
      } ],
      "path": "Extension.extension.extension.value[x]",
      "min": 0,
      "definition": "Use 95 for a 95% confidence interval.",
      "isModifier": false,
      "short": "Level of confidence interval, eg 0.95 for 95% confidence interval",
      "mapping": [ {
        "map": "N/A",
        "identity": "rim"
      } ],
      "type": [ {
        "code": "decimal"
      } ],
      "max": "1",
      "id": "Extension.extension:attributeEstimate.extension:level.value[x]",
      "base": {
        "max": "1",
        "min": 0,
        "path": "Extension.value[x]"
      },
      "isSummary": false
    }, {
      "constraint": [ {
        "key": "ele-1",
        "human": "All FHIR elements must have a @value or children",
        "xpath": "@value|f:*|h:div",
        "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1",
        "severity": "error",
        "expression": "hasValue() or (children().count() > id.count())"
      }, {
        "key": "ext-1",
        "human": "Must have either extensions or value[x], not both",
        "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
        "source": "http://hl7.org/fhir/StructureDefinition/Extension|4.0.1",
        "severity": "error",
        "expression": "extension.exists() != value.exists()"
      } ],
      "path": "Extension.extension.extension",
      "requirements": "Element `Evidence.statistic.attributeEstimate.range` is part of an existing definition because parent element `Evidence.statistic.attributeEstimate` requires a cross-version extension.\nElement `Evidence.statistic.attributeEstimate.range` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.attributeEstimate.range` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
      "min": 0,
      "definition": "R4B: `Evidence.statistic.attributeEstimate.range` (new:Range)",
      "isModifier": false,
      "short": "R4B: Lower and upper bound values of the attribute estimate (new)",
      "type": [ {
        "code": "Extension"
      } ],
      "sliceName": "range",
      "max": "1",
      "id": "Extension.extension:attributeEstimate.extension:range",
      "comment": "Element `Evidence.statistic.attributeEstimate.range` is part of an existing definition because parent element `Evidence.statistic.attributeEstimate` requires a cross-version extension.\nElement `Evidence.statistic.attributeEstimate.range` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.attributeEstimate.range` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
      "base": {
        "max": "*",
        "min": 0,
        "path": "Element.extension"
      },
      "isSummary": false
    }, {
      "path": "Extension.extension.extension.id",
      "min": 0,
      "definition": "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
      "isModifier": false,
      "short": "Unique id for inter-element referencing",
      "mapping": [ {
        "map": "n/a",
        "identity": "rim"
      } ],
      "type": [ {
        "code": "http://hl7.org/fhirpath/System.String",
        "extension": [ {
          "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
          "valueUrl": "string"
        } ]
      } ],
      "representation": [ "xmlAttr" ],
      "max": "1",
      "id": "Extension.extension:attributeEstimate.extension:range.id",
      "base": {
        "max": "1",
        "min": 0,
        "path": "Element.id"
      },
      "isSummary": false
    }, {
      "constraint": [ {
        "key": "ele-1",
        "human": "All FHIR elements must have a @value or children",
        "xpath": "@value|f:*|h:div",
        "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1",
        "severity": "error",
        "expression": "hasValue() or (children().count() > id.count())"
      }, {
        "key": "ext-1",
        "human": "Must have either extensions or value[x], not both",
        "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
        "source": "http://hl7.org/fhir/StructureDefinition/Extension|4.0.1",
        "severity": "error",
        "expression": "extension.exists() != value.exists()"
      } ],
      "path": "Extension.extension.extension.extension",
      "min": 0,
      "definition": "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
      "isModifier": false,
      "short": "Additional content defined by implementations",
      "mapping": [ {
        "map": "n/a",
        "identity": "rim"
      } ],
      "slicing": {
        "rules": "open",
        "description": "Extensions are always sliced by (at least) url",
        "discriminator": [ {
          "path": "url",
          "type": "value"
        } ]
      },
      "type": [ {
        "code": "Extension"
      } ],
      "alias": [ "extensions", "user content" ],
      "max": "*",
      "id": "Extension.extension:attributeEstimate.extension:range.extension",
      "comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
      "base": {
        "max": "*",
        "min": 0,
        "path": "Element.extension"
      },
      "isSummary": false
    }, {
      "path": "Extension.extension.extension.url",
      "min": 1,
      "definition": "Source of the definition for the extension code - a logical name or a URL.",
      "isModifier": false,
      "short": "identifies the meaning of the extension",
      "fixedUri": "range",
      "mapping": [ {
        "map": "N/A",
        "identity": "rim"
      } ],
      "type": [ {
        "code": "http://hl7.org/fhirpath/System.String",
        "extension": [ {
          "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
          "valueUrl": "uri"
        } ]
      } ],
      "representation": [ "xmlAttr" ],
      "max": "1",
      "id": "Extension.extension:attributeEstimate.extension:range.url",
      "comment": "The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.",
      "base": {
        "max": "1",
        "min": 1,
        "path": "Extension.url"
      },
      "isSummary": false
    }, {
      "constraint": [ {
        "key": "ele-1",
        "human": "All FHIR elements must have a @value or children",
        "xpath": "@value|f:*|h:div",
        "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1",
        "severity": "error",
        "expression": "hasValue() or (children().count() > id.count())"
      } ],
      "path": "Extension.extension.extension.value[x]",
      "min": 0,
      "definition": "Lower bound of confidence interval.",
      "isModifier": false,
      "short": "Lower and upper bound values of the attribute estimate",
      "mapping": [ {
        "map": "N/A",
        "identity": "rim"
      } ],
      "type": [ {
        "code": "Range"
      } ],
      "max": "1",
      "id": "Extension.extension:attributeEstimate.extension:range.value[x]",
      "base": {
        "max": "1",
        "min": 0,
        "path": "Extension.value[x]"
      },
      "isSummary": false
    }, {
      "constraint": [ {
        "key": "ele-1",
        "human": "All FHIR elements must have a @value or children",
        "xpath": "@value|f:*|h:div",
        "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1",
        "severity": "error",
        "expression": "hasValue() or (children().count() > id.count())"
      }, {
        "key": "ext-1",
        "human": "Must have either extensions or value[x], not both",
        "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
        "source": "http://hl7.org/fhir/StructureDefinition/Extension|4.0.1",
        "severity": "error",
        "expression": "extension.exists() != value.exists()"
      } ],
      "path": "Extension.extension.extension",
      "requirements": "Element `Evidence.statistic.attributeEstimate.attributeEstimate` is part of an existing definition because parent element `Evidence.statistic.attributeEstimate` requires a cross-version extension.\nElement `Evidence.statistic.attributeEstimate.attributeEstimate` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.attributeEstimate.attributeEstimate` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
      "min": 0,
      "definition": "R4B: `Evidence.statistic.attributeEstimate.attributeEstimate` (new:Evidence.statistic.attributeEstimate)",
      "isModifier": false,
      "short": "R4B: A nested attribute estimate; which is the attribute estimate of an attribute estimate (new)",
      "type": [ {
        "code": "Extension"
      } ],
      "sliceName": "attributeEstimate",
      "max": "*",
      "id": "Extension.extension:attributeEstimate.extension:attributeEstimate",
      "comment": "Element `Evidence.statistic.attributeEstimate.attributeEstimate` is part of an existing definition because parent element `Evidence.statistic.attributeEstimate` requires a cross-version extension.\nElement `Evidence.statistic.attributeEstimate.attributeEstimate` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.attributeEstimate.attributeEstimate` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).\nA nested attribute estimate; which is the attribute estimate of an attribute estimate",
      "base": {
        "max": "*",
        "min": 0,
        "path": "Element.extension"
      },
      "isSummary": false
    }, {
      "path": "Extension.extension.extension.id",
      "min": 0,
      "definition": "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
      "isModifier": false,
      "short": "Unique id for inter-element referencing",
      "mapping": [ {
        "map": "n/a",
        "identity": "rim"
      } ],
      "type": [ {
        "code": "http://hl7.org/fhirpath/System.String",
        "extension": [ {
          "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
          "valueUrl": "string"
        } ]
      } ],
      "representation": [ "xmlAttr" ],
      "max": "1",
      "id": "Extension.extension:attributeEstimate.extension:attributeEstimate.id",
      "base": {
        "max": "1",
        "min": 0,
        "path": "Element.id"
      },
      "isSummary": false
    }, {
      "constraint": [ {
        "key": "ele-1",
        "human": "All FHIR elements must have a @value or children",
        "xpath": "@value|f:*|h:div",
        "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1",
        "severity": "error",
        "expression": "hasValue() or (children().count() > id.count())"
      }, {
        "key": "ext-1",
        "human": "Must have either extensions or value[x], not both",
        "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
        "source": "http://hl7.org/fhir/StructureDefinition/Extension|4.0.1",
        "severity": "error",
        "expression": "extension.exists() != value.exists()"
      } ],
      "path": "Extension.extension.extension.extension",
      "min": 0,
      "definition": "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
      "isModifier": false,
      "short": "Additional content defined by implementations",
      "mapping": [ {
        "map": "n/a",
        "identity": "rim"
      } ],
      "slicing": {
        "rules": "open",
        "description": "Extensions are always sliced by (at least) url",
        "discriminator": [ {
          "path": "url",
          "type": "value"
        } ]
      },
      "type": [ {
        "code": "Extension"
      } ],
      "alias": [ "extensions", "user content" ],
      "max": "*",
      "id": "Extension.extension:attributeEstimate.extension:attributeEstimate.extension",
      "comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
      "base": {
        "max": "*",
        "min": 0,
        "path": "Element.extension"
      },
      "isSummary": false
    }, {
      "path": "Extension.extension.extension.url",
      "min": 1,
      "definition": "Source of the definition for the extension code - a logical name or a URL.",
      "isModifier": false,
      "short": "identifies the meaning of the extension",
      "fixedUri": "http://hl7.org/fhir/4.3/StructureDefinition/extension-Evidence.statistic.attributeEstimate",
      "mapping": [ {
        "map": "N/A",
        "identity": "rim"
      } ],
      "type": [ {
        "code": "http://hl7.org/fhirpath/System.String",
        "extension": [ {
          "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
          "valueUrl": "uri"
        } ]
      } ],
      "representation": [ "xmlAttr" ],
      "max": "1",
      "id": "Extension.extension:attributeEstimate.extension:attributeEstimate.url",
      "comment": "The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.",
      "base": {
        "max": "1",
        "min": 1,
        "path": "Extension.url"
      },
      "isSummary": false
    }, {
      "constraint": [ {
        "key": "ele-1",
        "human": "All FHIR elements must have a @value or children",
        "xpath": "@value|f:*|h:div",
        "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1",
        "severity": "error",
        "expression": "hasValue() or (children().count() > id.count())"
      } ],
      "path": "Extension.extension.extension.value[x]",
      "min": 0,
      "definition": "Value of extension - must be one of a constrained set of the data types (see [Extensibility](http://hl7.org/fhir/R4/extensibility.html) for a list).",
      "isModifier": false,
      "short": "Value of extension",
      "mapping": [ {
        "map": "N/A",
        "identity": "rim"
      } ],
      "type": [ {
        "code": "base64Binary"
      }, {
        "code": "boolean"
      }, {
        "code": "canonical"
      }, {
        "code": "code"
      }, {
        "code": "date"
      }, {
        "code": "dateTime"
      }, {
        "code": "decimal"
      }, {
        "code": "id"
      }, {
        "code": "instant"
      }, {
        "code": "integer"
      }, {
        "code": "markdown"
      }, {
        "code": "oid"
      }, {
        "code": "positiveInt"
      }, {
        "code": "string"
      }, {
        "code": "time"
      }, {
        "code": "unsignedInt"
      }, {
        "code": "uri"
      }, {
        "code": "url"
      }, {
        "code": "uuid"
      }, {
        "code": "Address"
      }, {
        "code": "Age"
      }, {
        "code": "Annotation"
      }, {
        "code": "Attachment"
      }, {
        "code": "CodeableConcept"
      }, {
        "code": "Coding"
      }, {
        "code": "ContactPoint"
      }, {
        "code": "Count"
      }, {
        "code": "Distance"
      }, {
        "code": "Duration"
      }, {
        "code": "HumanName"
      }, {
        "code": "Identifier"
      }, {
        "code": "Money"
      }, {
        "code": "Period"
      }, {
        "code": "Quantity"
      }, {
        "code": "Range"
      }, {
        "code": "Ratio"
      }, {
        "code": "Reference"
      }, {
        "code": "SampledData"
      }, {
        "code": "Signature"
      }, {
        "code": "Timing"
      }, {
        "code": "ContactDetail"
      }, {
        "code": "Contributor"
      }, {
        "code": "DataRequirement"
      }, {
        "code": "Expression"
      }, {
        "code": "ParameterDefinition"
      }, {
        "code": "RelatedArtifact"
      }, {
        "code": "TriggerDefinition"
      }, {
        "code": "UsageContext"
      }, {
        "code": "Dosage"
      }, {
        "code": "Meta"
      } ],
      "max": "0",
      "id": "Extension.extension:attributeEstimate.extension:attributeEstimate.value[x]",
      "base": {
        "max": "1",
        "min": 0,
        "path": "Extension.value[x]"
      },
      "isSummary": false
    }, {
      "path": "Extension.extension.url",
      "min": 1,
      "definition": "Source of the definition for the extension code - a logical name or a URL.",
      "isModifier": false,
      "short": "identifies the meaning of the extension",
      "fixedUri": "attributeEstimate",
      "mapping": [ {
        "map": "N/A",
        "identity": "rim"
      } ],
      "type": [ {
        "code": "http://hl7.org/fhirpath/System.String",
        "extension": [ {
          "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
          "valueUrl": "uri"
        } ]
      } ],
      "representation": [ "xmlAttr" ],
      "max": "1",
      "id": "Extension.extension:attributeEstimate.url",
      "comment": "The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.",
      "base": {
        "max": "1",
        "min": 1,
        "path": "Extension.url"
      },
      "isSummary": false
    }, {
      "constraint": [ {
        "key": "ele-1",
        "human": "All FHIR elements must have a @value or children",
        "xpath": "@value|f:*|h:div",
        "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1",
        "severity": "error",
        "expression": "hasValue() or (children().count() > id.count())"
      } ],
      "path": "Extension.extension.value[x]",
      "min": 0,
      "definition": "Value of extension - must be one of a constrained set of the data types (see [Extensibility](http://hl7.org/fhir/R4/extensibility.html) for a list).",
      "isModifier": false,
      "short": "Value of extension",
      "mapping": [ {
        "map": "N/A",
        "identity": "rim"
      } ],
      "type": [ {
        "code": "base64Binary"
      }, {
        "code": "boolean"
      }, {
        "code": "canonical"
      }, {
        "code": "code"
      }, {
        "code": "date"
      }, {
        "code": "dateTime"
      }, {
        "code": "decimal"
      }, {
        "code": "id"
      }, {
        "code": "instant"
      }, {
        "code": "integer"
      }, {
        "code": "markdown"
      }, {
        "code": "oid"
      }, {
        "code": "positiveInt"
      }, {
        "code": "string"
      }, {
        "code": "time"
      }, {
        "code": "unsignedInt"
      }, {
        "code": "uri"
      }, {
        "code": "url"
      }, {
        "code": "uuid"
      }, {
        "code": "Address"
      }, {
        "code": "Age"
      }, {
        "code": "Annotation"
      }, {
        "code": "Attachment"
      }, {
        "code": "CodeableConcept"
      }, {
        "code": "Coding"
      }, {
        "code": "ContactPoint"
      }, {
        "code": "Count"
      }, {
        "code": "Distance"
      }, {
        "code": "Duration"
      }, {
        "code": "HumanName"
      }, {
        "code": "Identifier"
      }, {
        "code": "Money"
      }, {
        "code": "Period"
      }, {
        "code": "Quantity"
      }, {
        "code": "Range"
      }, {
        "code": "Ratio"
      }, {
        "code": "Reference"
      }, {
        "code": "SampledData"
      }, {
        "code": "Signature"
      }, {
        "code": "Timing"
      }, {
        "code": "ContactDetail"
      }, {
        "code": "Contributor"
      }, {
        "code": "DataRequirement"
      }, {
        "code": "Expression"
      }, {
        "code": "ParameterDefinition"
      }, {
        "code": "RelatedArtifact"
      }, {
        "code": "TriggerDefinition"
      }, {
        "code": "UsageContext"
      }, {
        "code": "Dosage"
      }, {
        "code": "Meta"
      } ],
      "max": "0",
      "id": "Extension.extension:attributeEstimate.value[x]",
      "base": {
        "max": "1",
        "min": 0,
        "path": "Extension.value[x]"
      },
      "isSummary": false
    }, {
      "constraint": [ {
        "key": "ele-1",
        "human": "All FHIR elements must have a @value or children",
        "xpath": "@value|f:*|h:div",
        "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1",
        "severity": "error",
        "expression": "hasValue() or (children().count() > id.count())"
      }, {
        "key": "ext-1",
        "human": "Must have either extensions or value[x], not both",
        "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
        "source": "http://hl7.org/fhir/StructureDefinition/Extension|4.0.1",
        "severity": "error",
        "expression": "extension.exists() != value.exists()"
      } ],
      "path": "Extension.extension",
      "requirements": "Element `Evidence.statistic.modelCharacteristic` is part of an existing definition because parent element `Evidence.statistic` requires a cross-version extension.\nElement `Evidence.statistic.modelCharacteristic` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.modelCharacteristic` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
      "min": 0,
      "definition": "R4B: `Evidence.statistic.modelCharacteristic` (new:BackboneElement)",
      "isModifier": false,
      "short": "R4B: An aspect of the statistical model (new)",
      "type": [ {
        "code": "Extension"
      } ],
      "sliceName": "modelCharacteristic",
      "max": "*",
      "id": "Extension.extension:modelCharacteristic",
      "comment": "Element `Evidence.statistic.modelCharacteristic` is part of an existing definition because parent element `Evidence.statistic` requires a cross-version extension.\nElement `Evidence.statistic.modelCharacteristic` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.modelCharacteristic` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
      "base": {
        "max": "*",
        "min": 0,
        "path": "Element.extension"
      },
      "isSummary": false
    }, {
      "path": "Extension.extension.id",
      "min": 0,
      "definition": "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
      "isModifier": false,
      "short": "Unique id for inter-element referencing",
      "mapping": [ {
        "map": "n/a",
        "identity": "rim"
      } ],
      "type": [ {
        "code": "http://hl7.org/fhirpath/System.String",
        "extension": [ {
          "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
          "valueUrl": "string"
        } ]
      } ],
      "representation": [ "xmlAttr" ],
      "max": "1",
      "id": "Extension.extension:modelCharacteristic.id",
      "base": {
        "max": "1",
        "min": 0,
        "path": "Element.id"
      },
      "isSummary": false
    }, {
      "constraint": [ {
        "key": "ele-1",
        "human": "All FHIR elements must have a @value or children",
        "xpath": "@value|f:*|h:div",
        "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1",
        "severity": "error",
        "expression": "hasValue() or (children().count() > id.count())"
      }, {
        "key": "ext-1",
        "human": "Must have either extensions or value[x], not both",
        "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
        "source": "http://hl7.org/fhir/StructureDefinition/Extension|4.0.1",
        "severity": "error",
        "expression": "extension.exists() != value.exists()"
      } ],
      "path": "Extension.extension.extension",
      "min": 1,
      "definition": "An Extension",
      "isModifier": false,
      "short": "Extension",
      "slicing": {
        "rules": "open",
        "ordered": false,
        "description": "Extensions are always sliced by (at least) url",
        "discriminator": [ {
          "path": "url",
          "type": "value"
        } ]
      },
      "type": [ {
        "code": "Extension"
      } ],
      "max": "*",
      "id": "Extension.extension:modelCharacteristic.extension",
      "base": {
        "max": "*",
        "min": 0,
        "path": "Element.extension"
      },
      "isSummary": false
    }, {
      "constraint": [ {
        "key": "ele-1",
        "human": "All FHIR elements must have a @value or children",
        "xpath": "@value|f:*|h:div",
        "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1",
        "severity": "error",
        "expression": "hasValue() or (children().count() > id.count())"
      }, {
        "key": "ext-1",
        "human": "Must have either extensions or value[x], not both",
        "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
        "source": "http://hl7.org/fhir/StructureDefinition/Extension|4.0.1",
        "severity": "error",
        "expression": "extension.exists() != value.exists()"
      } ],
      "path": "Extension.extension.extension",
      "requirements": "Element `Evidence.statistic.modelCharacteristic.code` is part of an existing definition because parent element `Evidence.statistic.modelCharacteristic` requires a cross-version extension.\nElement `Evidence.statistic.modelCharacteristic.code` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.modelCharacteristic.code` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
      "min": 1,
      "definition": "R4B: `Evidence.statistic.modelCharacteristic.code` (new:CodeableConcept)",
      "isModifier": false,
      "short": "R4B: Model specification (new)",
      "type": [ {
        "code": "Extension"
      } ],
      "sliceName": "code",
      "max": "1",
      "id": "Extension.extension:modelCharacteristic.extension:code",
      "comment": "Element `Evidence.statistic.modelCharacteristic.code` is part of an existing definition because parent element `Evidence.statistic.modelCharacteristic` requires a cross-version extension.\nElement `Evidence.statistic.modelCharacteristic.code` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.modelCharacteristic.code` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
      "base": {
        "max": "*",
        "min": 0,
        "path": "Element.extension"
      },
      "isSummary": false
    }, {
      "path": "Extension.extension.extension.id",
      "min": 0,
      "definition": "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
      "isModifier": false,
      "short": "Unique id for inter-element referencing",
      "mapping": [ {
        "map": "n/a",
        "identity": "rim"
      } ],
      "type": [ {
        "code": "http://hl7.org/fhirpath/System.String",
        "extension": [ {
          "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
          "valueUrl": "string"
        } ]
      } ],
      "representation": [ "xmlAttr" ],
      "max": "1",
      "id": "Extension.extension:modelCharacteristic.extension:code.id",
      "base": {
        "max": "1",
        "min": 0,
        "path": "Element.id"
      },
      "isSummary": false
    }, {
      "constraint": [ {
        "key": "ele-1",
        "human": "All FHIR elements must have a @value or children",
        "xpath": "@value|f:*|h:div",
        "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1",
        "severity": "error",
        "expression": "hasValue() or (children().count() > id.count())"
      }, {
        "key": "ext-1",
        "human": "Must have either extensions or value[x], not both",
        "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
        "source": "http://hl7.org/fhir/StructureDefinition/Extension|4.0.1",
        "severity": "error",
        "expression": "extension.exists() != value.exists()"
      } ],
      "path": "Extension.extension.extension.extension",
      "min": 0,
      "definition": "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
      "isModifier": false,
      "short": "Additional content defined by implementations",
      "mapping": [ {
        "map": "n/a",
        "identity": "rim"
      } ],
      "slicing": {
        "rules": "open",
        "description": "Extensions are always sliced by (at least) url",
        "discriminator": [ {
          "path": "url",
          "type": "value"
        } ]
      },
      "type": [ {
        "code": "Extension"
      } ],
      "alias": [ "extensions", "user content" ],
      "max": "*",
      "id": "Extension.extension:modelCharacteristic.extension:code.extension",
      "comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
      "base": {
        "max": "*",
        "min": 0,
        "path": "Element.extension"
      },
      "isSummary": false
    }, {
      "path": "Extension.extension.extension.url",
      "min": 1,
      "definition": "Source of the definition for the extension code - a logical name or a URL.",
      "isModifier": false,
      "short": "identifies the meaning of the extension",
      "fixedUri": "code",
      "mapping": [ {
        "map": "N/A",
        "identity": "rim"
      } ],
      "type": [ {
        "code": "http://hl7.org/fhirpath/System.String",
        "extension": [ {
          "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
          "valueUrl": "uri"
        } ]
      } ],
      "representation": [ "xmlAttr" ],
      "max": "1",
      "id": "Extension.extension:modelCharacteristic.extension:code.url",
      "comment": "The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.",
      "base": {
        "max": "1",
        "min": 1,
        "path": "Extension.url"
      },
      "isSummary": false
    }, {
      "constraint": [ {
        "key": "ele-1",
        "human": "All FHIR elements must have a @value or children",
        "xpath": "@value|f:*|h:div",
        "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1",
        "severity": "error",
        "expression": "hasValue() or (children().count() > id.count())"
      } ],
      "path": "Extension.extension.extension.value[x]",
      "min": 1,
      "definition": "Description of a component of the method to generate the statistic.",
      "isModifier": false,
      "short": "Model specification",
      "mapping": [ {
        "map": "N/A",
        "identity": "rim"
      } ],
      "type": [ {
        "code": "CodeableConcept"
      } ],
      "binding": {
        "strength": "extensible",
        "valueSet": "http://hl7.org/fhir/uv/xver/ValueSet/R4B-statistic-model-code-for-R4|0.1.0"
      },
      "max": "1",
      "id": "Extension.extension:modelCharacteristic.extension:code.value[x]",
      "base": {
        "max": "1",
        "min": 0,
        "path": "Extension.value[x]"
      },
      "isSummary": false
    }, {
      "constraint": [ {
        "key": "ele-1",
        "human": "All FHIR elements must have a @value or children",
        "xpath": "@value|f:*|h:div",
        "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1",
        "severity": "error",
        "expression": "hasValue() or (children().count() > id.count())"
      }, {
        "key": "ext-1",
        "human": "Must have either extensions or value[x], not both",
        "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
        "source": "http://hl7.org/fhir/StructureDefinition/Extension|4.0.1",
        "severity": "error",
        "expression": "extension.exists() != value.exists()"
      } ],
      "path": "Extension.extension.extension",
      "requirements": "Element `Evidence.statistic.modelCharacteristic.value` is part of an existing definition because parent element `Evidence.statistic.modelCharacteristic` requires a cross-version extension.\nElement `Evidence.statistic.modelCharacteristic.value` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.modelCharacteristic.value` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
      "min": 0,
      "definition": "R4B: `Evidence.statistic.modelCharacteristic.value` (new:Quantity[SimpleQuantity])",
      "isModifier": false,
      "short": "R4B: Numerical value to complete model specification (new)",
      "type": [ {
        "code": "Extension"
      } ],
      "sliceName": "value",
      "max": "1",
      "id": "Extension.extension:modelCharacteristic.extension:value",
      "comment": "Element `Evidence.statistic.modelCharacteristic.value` is part of an existing definition because parent element `Evidence.statistic.modelCharacteristic` requires a cross-version extension.\nElement `Evidence.statistic.modelCharacteristic.value` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.modelCharacteristic.value` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
      "base": {
        "max": "*",
        "min": 0,
        "path": "Element.extension"
      },
      "isSummary": false
    }, {
      "path": "Extension.extension.extension.id",
      "min": 0,
      "definition": "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
      "isModifier": false,
      "short": "Unique id for inter-element referencing",
      "mapping": [ {
        "map": "n/a",
        "identity": "rim"
      } ],
      "type": [ {
        "code": "http://hl7.org/fhirpath/System.String",
        "extension": [ {
          "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
          "valueUrl": "string"
        } ]
      } ],
      "representation": [ "xmlAttr" ],
      "max": "1",
      "id": "Extension.extension:modelCharacteristic.extension:value.id",
      "base": {
        "max": "1",
        "min": 0,
        "path": "Element.id"
      },
      "isSummary": false
    }, {
      "constraint": [ {
        "key": "ele-1",
        "human": "All FHIR elements must have a @value or children",
        "xpath": "@value|f:*|h:div",
        "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1",
        "severity": "error",
        "expression": "hasValue() or (children().count() > id.count())"
      }, {
        "key": "ext-1",
        "human": "Must have either extensions or value[x], not both",
        "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
        "source": "http://hl7.org/fhir/StructureDefinition/Extension|4.0.1",
        "severity": "error",
        "expression": "extension.exists() != value.exists()"
      } ],
      "path": "Extension.extension.extension.extension",
      "min": 0,
      "definition": "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
      "isModifier": false,
      "short": "Additional content defined by implementations",
      "mapping": [ {
        "map": "n/a",
        "identity": "rim"
      } ],
      "slicing": {
        "rules": "open",
        "description": "Extensions are always sliced by (at least) url",
        "discriminator": [ {
          "path": "url",
          "type": "value"
        } ]
      },
      "type": [ {
        "code": "Extension"
      } ],
      "alias": [ "extensions", "user content" ],
      "max": "*",
      "id": "Extension.extension:modelCharacteristic.extension:value.extension",
      "comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
      "base": {
        "max": "*",
        "min": 0,
        "path": "Element.extension"
      },
      "isSummary": false
    }, {
      "path": "Extension.extension.extension.url",
      "min": 1,
      "definition": "Source of the definition for the extension code - a logical name or a URL.",
      "isModifier": false,
      "short": "identifies the meaning of the extension",
      "fixedUri": "value",
      "mapping": [ {
        "map": "N/A",
        "identity": "rim"
      } ],
      "type": [ {
        "code": "http://hl7.org/fhirpath/System.String",
        "extension": [ {
          "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
          "valueUrl": "uri"
        } ]
      } ],
      "representation": [ "xmlAttr" ],
      "max": "1",
      "id": "Extension.extension:modelCharacteristic.extension:value.url",
      "comment": "The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.",
      "base": {
        "max": "1",
        "min": 1,
        "path": "Extension.url"
      },
      "isSummary": false
    }, {
      "constraint": [ {
        "key": "ele-1",
        "human": "All FHIR elements must have a @value or children",
        "xpath": "@value|f:*|h:div",
        "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1",
        "severity": "error",
        "expression": "hasValue() or (children().count() > id.count())"
      } ],
      "path": "Extension.extension.extension.value[x]",
      "min": 0,
      "definition": "Further specification of the quantified value of the component of the method to generate the statistic.",
      "isModifier": false,
      "short": "Numerical value to complete model specification",
      "mapping": [ {
        "map": "N/A",
        "identity": "rim"
      } ],
      "type": [ {
        "code": "Quantity",
        "profile": [ "http://hl7.org/fhir/StructureDefinition/SimpleQuantity|4.0.1" ]
      } ],
      "max": "1",
      "id": "Extension.extension:modelCharacteristic.extension:value.value[x]",
      "base": {
        "max": "1",
        "min": 0,
        "path": "Extension.value[x]"
      },
      "isSummary": false
    }, {
      "constraint": [ {
        "key": "ele-1",
        "human": "All FHIR elements must have a @value or children",
        "xpath": "@value|f:*|h:div",
        "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1",
        "severity": "error",
        "expression": "hasValue() or (children().count() > id.count())"
      }, {
        "key": "ext-1",
        "human": "Must have either extensions or value[x], not both",
        "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
        "source": "http://hl7.org/fhir/StructureDefinition/Extension|4.0.1",
        "severity": "error",
        "expression": "extension.exists() != value.exists()"
      } ],
      "path": "Extension.extension.extension",
      "requirements": "Element `Evidence.statistic.modelCharacteristic.variable` is part of an existing definition because parent element `Evidence.statistic.modelCharacteristic` requires a cross-version extension.\nElement `Evidence.statistic.modelCharacteristic.variable` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.modelCharacteristic.variable` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
      "min": 0,
      "definition": "R4B: `Evidence.statistic.modelCharacteristic.variable` (new:BackboneElement)",
      "isModifier": false,
      "short": "R4B: A variable adjusted for in the adjusted analysis (new)",
      "type": [ {
        "code": "Extension"
      } ],
      "sliceName": "variable",
      "max": "*",
      "id": "Extension.extension:modelCharacteristic.extension:variable",
      "comment": "Element `Evidence.statistic.modelCharacteristic.variable` is part of an existing definition because parent element `Evidence.statistic.modelCharacteristic` requires a cross-version extension.\nElement `Evidence.statistic.modelCharacteristic.variable` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.modelCharacteristic.variable` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
      "base": {
        "max": "*",
        "min": 0,
        "path": "Element.extension"
      },
      "isSummary": false
    }, {
      "path": "Extension.extension.extension.id",
      "min": 0,
      "definition": "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
      "isModifier": false,
      "short": "Unique id for inter-element referencing",
      "mapping": [ {
        "map": "n/a",
        "identity": "rim"
      } ],
      "type": [ {
        "code": "http://hl7.org/fhirpath/System.String",
        "extension": [ {
          "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
          "valueUrl": "string"
        } ]
      } ],
      "representation": [ "xmlAttr" ],
      "max": "1",
      "id": "Extension.extension:modelCharacteristic.extension:variable.id",
      "base": {
        "max": "1",
        "min": 0,
        "path": "Element.id"
      },
      "isSummary": false
    }, {
      "constraint": [ {
        "key": "ele-1",
        "human": "All FHIR elements must have a @value or children",
        "xpath": "@value|f:*|h:div",
        "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1",
        "severity": "error",
        "expression": "hasValue() or (children().count() > id.count())"
      }, {
        "key": "ext-1",
        "human": "Must have either extensions or value[x], not both",
        "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
        "source": "http://hl7.org/fhir/StructureDefinition/Extension|4.0.1",
        "severity": "error",
        "expression": "extension.exists() != value.exists()"
      } ],
      "path": "Extension.extension.extension.extension",
      "min": 1,
      "definition": "An Extension",
      "isModifier": false,
      "short": "Extension",
      "slicing": {
        "rules": "open",
        "ordered": false,
        "description": "Extensions are always sliced by (at least) url",
        "discriminator": [ {
          "path": "url",
          "type": "value"
        } ]
      },
      "type": [ {
        "code": "Extension"
      } ],
      "max": "*",
      "id": "Extension.extension:modelCharacteristic.extension:variable.extension",
      "base": {
        "max": "*",
        "min": 0,
        "path": "Element.extension"
      },
      "isSummary": false
    }, {
      "constraint": [ {
        "key": "ele-1",
        "human": "All FHIR elements must have a @value or children",
        "xpath": "@value|f:*|h:div",
        "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1",
        "severity": "error",
        "expression": "hasValue() or (children().count() > id.count())"
      }, {
        "key": "ext-1",
        "human": "Must have either extensions or value[x], not both",
        "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
        "source": "http://hl7.org/fhir/StructureDefinition/Extension|4.0.1",
        "severity": "error",
        "expression": "extension.exists() != value.exists()"
      } ],
      "path": "Extension.extension.extension.extension",
      "requirements": "Element `Evidence.statistic.modelCharacteristic.variable.variableDefinition` is part of an existing definition because parent element `Evidence.statistic.modelCharacteristic.variable` requires a cross-version extension.\nElement `Evidence.statistic.modelCharacteristic.variable.variableDefinition` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.modelCharacteristic.variable.variableDefinition` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
      "min": 1,
      "definition": "R4B: `Evidence.statistic.modelCharacteristic.variable.variableDefinition` (new:Reference(Group,EvidenceVariable))",
      "isModifier": false,
      "short": "R4B: Description of the variable (new)",
      "type": [ {
        "code": "Extension"
      } ],
      "sliceName": "variableDefinition",
      "max": "1",
      "id": "Extension.extension:modelCharacteristic.extension:variable.extension:variableDefinition",
      "comment": "Element `Evidence.statistic.modelCharacteristic.variable.variableDefinition` is part of an existing definition because parent element `Evidence.statistic.modelCharacteristic.variable` requires a cross-version extension.\nElement `Evidence.statistic.modelCharacteristic.variable.variableDefinition` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.modelCharacteristic.variable.variableDefinition` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
      "base": {
        "max": "*",
        "min": 0,
        "path": "Element.extension"
      },
      "isSummary": false
    }, {
      "path": "Extension.extension.extension.extension.id",
      "min": 0,
      "definition": "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
      "isModifier": false,
      "short": "Unique id for inter-element referencing",
      "mapping": [ {
        "map": "n/a",
        "identity": "rim"
      } ],
      "type": [ {
        "code": "http://hl7.org/fhirpath/System.String",
        "extension": [ {
          "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
          "valueUrl": "string"
        } ]
      } ],
      "representation": [ "xmlAttr" ],
      "max": "1",
      "id": "Extension.extension:modelCharacteristic.extension:variable.extension:variableDefinition.id",
      "base": {
        "max": "1",
        "min": 0,
        "path": "Element.id"
      },
      "isSummary": false
    }, {
      "constraint": [ {
        "key": "ele-1",
        "human": "All FHIR elements must have a @value or children",
        "xpath": "@value|f:*|h:div",
        "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1",
        "severity": "error",
        "expression": "hasValue() or (children().count() > id.count())"
      }, {
        "key": "ext-1",
        "human": "Must have either extensions or value[x], not both",
        "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
        "source": "http://hl7.org/fhir/StructureDefinition/Extension|4.0.1",
        "severity": "error",
        "expression": "extension.exists() != value.exists()"
      } ],
      "path": "Extension.extension.extension.extension.extension",
      "min": 0,
      "definition": "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
      "isModifier": false,
      "short": "Additional content defined by implementations",
      "mapping": [ {
        "map": "n/a",
        "identity": "rim"
      } ],
      "slicing": {
        "rules": "open",
        "description": "Extensions are always sliced by (at least) url",
        "discriminator": [ {
          "path": "url",
          "type": "value"
        } ]
      },
      "type": [ {
        "code": "Extension"
      } ],
      "alias": [ "extensions", "user content" ],
      "max": "*",
      "id": "Extension.extension:modelCharacteristic.extension:variable.extension:variableDefinition.extension",
      "comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
      "base": {
        "max": "*",
        "min": 0,
        "path": "Element.extension"
      },
      "isSummary": false
    }, {
      "path": "Extension.extension.extension.extension.url",
      "min": 1,
      "definition": "Source of the definition for the extension code - a logical name or a URL.",
      "isModifier": false,
      "short": "identifies the meaning of the extension",
      "fixedUri": "variableDefinition",
      "mapping": [ {
        "map": "N/A",
        "identity": "rim"
      } ],
      "type": [ {
        "code": "http://hl7.org/fhirpath/System.String",
        "extension": [ {
          "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
          "valueUrl": "uri"
        } ]
      } ],
      "representation": [ "xmlAttr" ],
      "max": "1",
      "id": "Extension.extension:modelCharacteristic.extension:variable.extension:variableDefinition.url",
      "comment": "The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.",
      "base": {
        "max": "1",
        "min": 1,
        "path": "Extension.url"
      },
      "isSummary": false
    }, {
      "constraint": [ {
        "key": "ele-1",
        "human": "All FHIR elements must have a @value or children",
        "xpath": "@value|f:*|h:div",
        "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1",
        "severity": "error",
        "expression": "hasValue() or (children().count() > id.count())"
      } ],
      "path": "Extension.extension.extension.extension.value[x]",
      "min": 1,
      "definition": "Description of the variable.",
      "isModifier": false,
      "short": "Description of the variable",
      "mapping": [ {
        "map": "N/A",
        "identity": "rim"
      } ],
      "type": [ {
        "code": "Reference",
        "targetProfile": [ "http://hl7.org/fhir/4.3/StructureDefinition/profile-Group|0.1.0", "http://hl7.org/fhir/StructureDefinition/Group|4.0.1", "http://hl7.org/fhir/4.3/StructureDefinition/profile-EvidenceVariable|0.1.0", "http://hl7.org/fhir/StructureDefinition/EvidenceVariable|4.0.1" ]
      } ],
      "max": "1",
      "id": "Extension.extension:modelCharacteristic.extension:variable.extension:variableDefinition.value[x]",
      "base": {
        "max": "1",
        "min": 0,
        "path": "Extension.value[x]"
      },
      "isSummary": false
    }, {
      "constraint": [ {
        "key": "ele-1",
        "human": "All FHIR elements must have a @value or children",
        "xpath": "@value|f:*|h:div",
        "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1",
        "severity": "error",
        "expression": "hasValue() or (children().count() > id.count())"
      }, {
        "key": "ext-1",
        "human": "Must have either extensions or value[x], not both",
        "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
        "source": "http://hl7.org/fhir/StructureDefinition/Extension|4.0.1",
        "severity": "error",
        "expression": "extension.exists() != value.exists()"
      } ],
      "path": "Extension.extension.extension.extension",
      "requirements": "Element `Evidence.statistic.modelCharacteristic.variable.handling` is part of an existing definition because parent element `Evidence.statistic.modelCharacteristic.variable` requires a cross-version extension.\nElement `Evidence.statistic.modelCharacteristic.variable.handling` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.modelCharacteristic.variable.handling` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
      "min": 0,
      "definition": "R4B: `Evidence.statistic.modelCharacteristic.variable.handling` (new:code)",
      "isModifier": false,
      "short": "R4B: continuous | dichotomous | ordinal | polychotomous (new)",
      "type": [ {
        "code": "Extension"
      } ],
      "sliceName": "handling",
      "max": "1",
      "id": "Extension.extension:modelCharacteristic.extension:variable.extension:handling",
      "comment": "Element `Evidence.statistic.modelCharacteristic.variable.handling` is part of an existing definition because parent element `Evidence.statistic.modelCharacteristic.variable` requires a cross-version extension.\nElement `Evidence.statistic.modelCharacteristic.variable.handling` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.modelCharacteristic.variable.handling` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
      "base": {
        "max": "*",
        "min": 0,
        "path": "Element.extension"
      },
      "isSummary": false
    }, {
      "path": "Extension.extension.extension.extension.id",
      "min": 0,
      "definition": "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
      "isModifier": false,
      "short": "Unique id for inter-element referencing",
      "mapping": [ {
        "map": "n/a",
        "identity": "rim"
      } ],
      "type": [ {
        "code": "http://hl7.org/fhirpath/System.String",
        "extension": [ {
          "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
          "valueUrl": "string"
        } ]
      } ],
      "representation": [ "xmlAttr" ],
      "max": "1",
      "id": "Extension.extension:modelCharacteristic.extension:variable.extension:handling.id",
      "base": {
        "max": "1",
        "min": 0,
        "path": "Element.id"
      },
      "isSummary": false
    }, {
      "constraint": [ {
        "key": "ele-1",
        "human": "All FHIR elements must have a @value or children",
        "xpath": "@value|f:*|h:div",
        "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1",
        "severity": "error",
        "expression": "hasValue() or (children().count() > id.count())"
      }, {
        "key": "ext-1",
        "human": "Must have either extensions or value[x], not both",
        "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
        "source": "http://hl7.org/fhir/StructureDefinition/Extension|4.0.1",
        "severity": "error",
        "expression": "extension.exists() != value.exists()"
      } ],
      "path": "Extension.extension.extension.extension.extension",
      "min": 0,
      "definition": "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
      "isModifier": false,
      "short": "Additional content defined by implementations",
      "mapping": [ {
        "map": "n/a",
        "identity": "rim"
      } ],
      "slicing": {
        "rules": "open",
        "description": "Extensions are always sliced by (at least) url",
        "discriminator": [ {
          "path": "url",
          "type": "value"
        } ]
      },
      "type": [ {
        "code": "Extension"
      } ],
      "alias": [ "extensions", "user content" ],
      "max": "*",
      "id": "Extension.extension:modelCharacteristic.extension:variable.extension:handling.extension",
      "comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
      "base": {
        "max": "*",
        "min": 0,
        "path": "Element.extension"
      },
      "isSummary": false
    }, {
      "path": "Extension.extension.extension.extension.url",
      "min": 1,
      "definition": "Source of the definition for the extension code - a logical name or a URL.",
      "isModifier": false,
      "short": "identifies the meaning of the extension",
      "fixedUri": "handling",
      "mapping": [ {
        "map": "N/A",
        "identity": "rim"
      } ],
      "type": [ {
        "code": "http://hl7.org/fhirpath/System.String",
        "extension": [ {
          "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
          "valueUrl": "uri"
        } ]
      } ],
      "representation": [ "xmlAttr" ],
      "max": "1",
      "id": "Extension.extension:modelCharacteristic.extension:variable.extension:handling.url",
      "comment": "The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.",
      "base": {
        "max": "1",
        "min": 1,
        "path": "Extension.url"
      },
      "isSummary": false
    }, {
      "constraint": [ {
        "key": "ele-1",
        "human": "All FHIR elements must have a @value or children",
        "xpath": "@value|f:*|h:div",
        "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1",
        "severity": "error",
        "expression": "hasValue() or (children().count() > id.count())"
      } ],
      "path": "Extension.extension.extension.extension.value[x]",
      "min": 0,
      "definition": "How the variable is classified for use in adjusted analysis.",
      "isModifier": false,
      "short": "continuous | dichotomous | ordinal | polychotomous",
      "mapping": [ {
        "map": "N/A",
        "identity": "rim"
      } ],
      "type": [ {
        "code": "code"
      } ],
      "binding": {
        "strength": "required",
        "valueSet": "http://hl7.org/fhir/uv/xver/ValueSet/R4B-variable-handling-for-R4|0.1.0"
      },
      "max": "1",
      "id": "Extension.extension:modelCharacteristic.extension:variable.extension:handling.value[x]",
      "base": {
        "max": "1",
        "min": 0,
        "path": "Extension.value[x]"
      },
      "isSummary": false
    }, {
      "constraint": [ {
        "key": "ele-1",
        "human": "All FHIR elements must have a @value or children",
        "xpath": "@value|f:*|h:div",
        "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1",
        "severity": "error",
        "expression": "hasValue() or (children().count() > id.count())"
      }, {
        "key": "ext-1",
        "human": "Must have either extensions or value[x], not both",
        "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
        "source": "http://hl7.org/fhir/StructureDefinition/Extension|4.0.1",
        "severity": "error",
        "expression": "extension.exists() != value.exists()"
      } ],
      "path": "Extension.extension.extension.extension",
      "requirements": "Element `Evidence.statistic.modelCharacteristic.variable.valueCategory` is part of an existing definition because parent element `Evidence.statistic.modelCharacteristic.variable` requires a cross-version extension.\nElement `Evidence.statistic.modelCharacteristic.variable.valueCategory` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.modelCharacteristic.variable.valueCategory` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
      "min": 0,
      "definition": "R4B: `Evidence.statistic.modelCharacteristic.variable.valueCategory` (new:CodeableConcept)",
      "isModifier": false,
      "short": "R4B: Description for grouping of ordinal or polychotomous variables (new)",
      "type": [ {
        "code": "Extension"
      } ],
      "sliceName": "valueCategory",
      "max": "*",
      "id": "Extension.extension:modelCharacteristic.extension:variable.extension:valueCategory",
      "comment": "Element `Evidence.statistic.modelCharacteristic.variable.valueCategory` is part of an existing definition because parent element `Evidence.statistic.modelCharacteristic.variable` requires a cross-version extension.\nElement `Evidence.statistic.modelCharacteristic.variable.valueCategory` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.modelCharacteristic.variable.valueCategory` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
      "base": {
        "max": "*",
        "min": 0,
        "path": "Element.extension"
      },
      "isSummary": false
    }, {
      "path": "Extension.extension.extension.extension.id",
      "min": 0,
      "definition": "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
      "isModifier": false,
      "short": "Unique id for inter-element referencing",
      "mapping": [ {
        "map": "n/a",
        "identity": "rim"
      } ],
      "type": [ {
        "code": "http://hl7.org/fhirpath/System.String",
        "extension": [ {
          "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
          "valueUrl": "string"
        } ]
      } ],
      "representation": [ "xmlAttr" ],
      "max": "1",
      "id": "Extension.extension:modelCharacteristic.extension:variable.extension:valueCategory.id",
      "base": {
        "max": "1",
        "min": 0,
        "path": "Element.id"
      },
      "isSummary": false
    }, {
      "constraint": [ {
        "key": "ele-1",
        "human": "All FHIR elements must have a @value or children",
        "xpath": "@value|f:*|h:div",
        "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1",
        "severity": "error",
        "expression": "hasValue() or (children().count() > id.count())"
      }, {
        "key": "ext-1",
        "human": "Must have either extensions or value[x], not both",
        "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
        "source": "http://hl7.org/fhir/StructureDefinition/Extension|4.0.1",
        "severity": "error",
        "expression": "extension.exists() != value.exists()"
      } ],
      "path": "Extension.extension.extension.extension.extension",
      "min": 0,
      "definition": "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
      "isModifier": false,
      "short": "Additional content defined by implementations",
      "mapping": [ {
        "map": "n/a",
        "identity": "rim"
      } ],
      "slicing": {
        "rules": "open",
        "description": "Extensions are always sliced by (at least) url",
        "discriminator": [ {
          "path": "url",
          "type": "value"
        } ]
      },
      "type": [ {
        "code": "Extension"
      } ],
      "alias": [ "extensions", "user content" ],
      "max": "*",
      "id": "Extension.extension:modelCharacteristic.extension:variable.extension:valueCategory.extension",
      "comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
      "base": {
        "max": "*",
        "min": 0,
        "path": "Element.extension"
      },
      "isSummary": false
    }, {
      "path": "Extension.extension.extension.extension.url",
      "min": 1,
      "definition": "Source of the definition for the extension code - a logical name or a URL.",
      "isModifier": false,
      "short": "identifies the meaning of the extension",
      "fixedUri": "valueCategory",
      "mapping": [ {
        "map": "N/A",
        "identity": "rim"
      } ],
      "type": [ {
        "code": "http://hl7.org/fhirpath/System.String",
        "extension": [ {
          "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
          "valueUrl": "uri"
        } ]
      } ],
      "representation": [ "xmlAttr" ],
      "max": "1",
      "id": "Extension.extension:modelCharacteristic.extension:variable.extension:valueCategory.url",
      "comment": "The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.",
      "base": {
        "max": "1",
        "min": 1,
        "path": "Extension.url"
      },
      "isSummary": false
    }, {
      "constraint": [ {
        "key": "ele-1",
        "human": "All FHIR elements must have a @value or children",
        "xpath": "@value|f:*|h:div",
        "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1",
        "severity": "error",
        "expression": "hasValue() or (children().count() > id.count())"
      } ],
      "path": "Extension.extension.extension.extension.value[x]",
      "min": 0,
      "definition": "Description for grouping of ordinal or polychotomous variables.",
      "isModifier": false,
      "short": "Description for grouping of ordinal or polychotomous variables",
      "mapping": [ {
        "map": "N/A",
        "identity": "rim"
      } ],
      "type": [ {
        "code": "CodeableConcept"
      } ],
      "max": "1",
      "id": "Extension.extension:modelCharacteristic.extension:variable.extension:valueCategory.value[x]",
      "base": {
        "max": "1",
        "min": 0,
        "path": "Extension.value[x]"
      },
      "isSummary": false
    }, {
      "constraint": [ {
        "key": "ele-1",
        "human": "All FHIR elements must have a @value or children",
        "xpath": "@value|f:*|h:div",
        "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1",
        "severity": "error",
        "expression": "hasValue() or (children().count() > id.count())"
      }, {
        "key": "ext-1",
        "human": "Must have either extensions or value[x], not both",
        "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
        "source": "http://hl7.org/fhir/StructureDefinition/Extension|4.0.1",
        "severity": "error",
        "expression": "extension.exists() != value.exists()"
      } ],
      "path": "Extension.extension.extension.extension",
      "requirements": "Element `Evidence.statistic.modelCharacteristic.variable.valueQuantity` is part of an existing definition because parent element `Evidence.statistic.modelCharacteristic.variable` requires a cross-version extension.\nElement `Evidence.statistic.modelCharacteristic.variable.valueQuantity` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.modelCharacteristic.variable.valueQuantity` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
      "min": 0,
      "definition": "R4B: `Evidence.statistic.modelCharacteristic.variable.valueQuantity` (new:Quantity)",
      "isModifier": false,
      "short": "R4B: Discrete value for grouping of ordinal or polychotomous variables (new)",
      "type": [ {
        "code": "Extension"
      } ],
      "sliceName": "valueQuantity",
      "max": "*",
      "id": "Extension.extension:modelCharacteristic.extension:variable.extension:valueQuantity",
      "comment": "Element `Evidence.statistic.modelCharacteristic.variable.valueQuantity` is part of an existing definition because parent element `Evidence.statistic.modelCharacteristic.variable` requires a cross-version extension.\nElement `Evidence.statistic.modelCharacteristic.variable.valueQuantity` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.modelCharacteristic.variable.valueQuantity` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
      "base": {
        "max": "*",
        "min": 0,
        "path": "Element.extension"
      },
      "isSummary": false
    }, {
      "path": "Extension.extension.extension.extension.id",
      "min": 0,
      "definition": "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
      "isModifier": false,
      "short": "Unique id for inter-element referencing",
      "mapping": [ {
        "map": "n/a",
        "identity": "rim"
      } ],
      "type": [ {
        "code": "http://hl7.org/fhirpath/System.String",
        "extension": [ {
          "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
          "valueUrl": "string"
        } ]
      } ],
      "representation": [ "xmlAttr" ],
      "max": "1",
      "id": "Extension.extension:modelCharacteristic.extension:variable.extension:valueQuantity.id",
      "base": {
        "max": "1",
        "min": 0,
        "path": "Element.id"
      },
      "isSummary": false
    }, {
      "constraint": [ {
        "key": "ele-1",
        "human": "All FHIR elements must have a @value or children",
        "xpath": "@value|f:*|h:div",
        "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1",
        "severity": "error",
        "expression": "hasValue() or (children().count() > id.count())"
      }, {
        "key": "ext-1",
        "human": "Must have either extensions or value[x], not both",
        "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
        "source": "http://hl7.org/fhir/StructureDefinition/Extension|4.0.1",
        "severity": "error",
        "expression": "extension.exists() != value.exists()"
      } ],
      "path": "Extension.extension.extension.extension.extension",
      "min": 0,
      "definition": "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
      "isModifier": false,
      "short": "Additional content defined by implementations",
      "mapping": [ {
        "map": "n/a",
        "identity": "rim"
      } ],
      "slicing": {
        "rules": "open",
        "description": "Extensions are always sliced by (at least) url",
        "discriminator": [ {
          "path": "url",
          "type": "value"
        } ]
      },
      "type": [ {
        "code": "Extension"
      } ],
      "alias": [ "extensions", "user content" ],
      "max": "*",
      "id": "Extension.extension:modelCharacteristic.extension:variable.extension:valueQuantity.extension",
      "comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
      "base": {
        "max": "*",
        "min": 0,
        "path": "Element.extension"
      },
      "isSummary": false
    }, {
      "path": "Extension.extension.extension.extension.url",
      "min": 1,
      "definition": "Source of the definition for the extension code - a logical name or a URL.",
      "isModifier": false,
      "short": "identifies the meaning of the extension",
      "fixedUri": "valueQuantity",
      "mapping": [ {
        "map": "N/A",
        "identity": "rim"
      } ],
      "type": [ {
        "code": "http://hl7.org/fhirpath/System.String",
        "extension": [ {
          "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
          "valueUrl": "uri"
        } ]
      } ],
      "representation": [ "xmlAttr" ],
      "max": "1",
      "id": "Extension.extension:modelCharacteristic.extension:variable.extension:valueQuantity.url",
      "comment": "The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.",
      "base": {
        "max": "1",
        "min": 1,
        "path": "Extension.url"
      },
      "isSummary": false
    }, {
      "constraint": [ {
        "key": "ele-1",
        "human": "All FHIR elements must have a @value or children",
        "xpath": "@value|f:*|h:div",
        "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1",
        "severity": "error",
        "expression": "hasValue() or (children().count() > id.count())"
      } ],
      "path": "Extension.extension.extension.extension.value[x]",
      "min": 0,
      "definition": "Discrete value for grouping of ordinal or polychotomous variables.",
      "isModifier": false,
      "short": "Discrete value for grouping of ordinal or polychotomous variables",
      "mapping": [ {
        "map": "N/A",
        "identity": "rim"
      } ],
      "type": [ {
        "code": "Quantity"
      } ],
      "max": "1",
      "id": "Extension.extension:modelCharacteristic.extension:variable.extension:valueQuantity.value[x]",
      "base": {
        "max": "1",
        "min": 0,
        "path": "Extension.value[x]"
      },
      "isSummary": false
    }, {
      "constraint": [ {
        "key": "ele-1",
        "human": "All FHIR elements must have a @value or children",
        "xpath": "@value|f:*|h:div",
        "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1",
        "severity": "error",
        "expression": "hasValue() or (children().count() > id.count())"
      }, {
        "key": "ext-1",
        "human": "Must have either extensions or value[x], not both",
        "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
        "source": "http://hl7.org/fhir/StructureDefinition/Extension|4.0.1",
        "severity": "error",
        "expression": "extension.exists() != value.exists()"
      } ],
      "path": "Extension.extension.extension.extension",
      "requirements": "Element `Evidence.statistic.modelCharacteristic.variable.valueRange` is part of an existing definition because parent element `Evidence.statistic.modelCharacteristic.variable` requires a cross-version extension.\nElement `Evidence.statistic.modelCharacteristic.variable.valueRange` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.modelCharacteristic.variable.valueRange` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
      "min": 0,
      "definition": "R4B: `Evidence.statistic.modelCharacteristic.variable.valueRange` (new:Range)",
      "isModifier": false,
      "short": "R4B: Range of values for grouping of ordinal or polychotomous variables (new)",
      "type": [ {
        "code": "Extension"
      } ],
      "sliceName": "valueRange",
      "max": "*",
      "id": "Extension.extension:modelCharacteristic.extension:variable.extension:valueRange",
      "comment": "Element `Evidence.statistic.modelCharacteristic.variable.valueRange` is part of an existing definition because parent element `Evidence.statistic.modelCharacteristic.variable` requires a cross-version extension.\nElement `Evidence.statistic.modelCharacteristic.variable.valueRange` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.modelCharacteristic.variable.valueRange` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
      "base": {
        "max": "*",
        "min": 0,
        "path": "Element.extension"
      },
      "isSummary": false
    }, {
      "path": "Extension.extension.extension.extension.id",
      "min": 0,
      "definition": "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
      "isModifier": false,
      "short": "Unique id for inter-element referencing",
      "mapping": [ {
        "map": "n/a",
        "identity": "rim"
      } ],
      "type": [ {
        "code": "http://hl7.org/fhirpath/System.String",
        "extension": [ {
          "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
          "valueUrl": "string"
        } ]
      } ],
      "representation": [ "xmlAttr" ],
      "max": "1",
      "id": "Extension.extension:modelCharacteristic.extension:variable.extension:valueRange.id",
      "base": {
        "max": "1",
        "min": 0,
        "path": "Element.id"
      },
      "isSummary": false
    }, {
      "constraint": [ {
        "key": "ele-1",
        "human": "All FHIR elements must have a @value or children",
        "xpath": "@value|f:*|h:div",
        "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1",
        "severity": "error",
        "expression": "hasValue() or (children().count() > id.count())"
      }, {
        "key": "ext-1",
        "human": "Must have either extensions or value[x], not both",
        "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
        "source": "http://hl7.org/fhir/StructureDefinition/Extension|4.0.1",
        "severity": "error",
        "expression": "extension.exists() != value.exists()"
      } ],
      "path": "Extension.extension.extension.extension.extension",
      "min": 0,
      "definition": "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
      "isModifier": false,
      "short": "Additional content defined by implementations",
      "mapping": [ {
        "map": "n/a",
        "identity": "rim"
      } ],
      "slicing": {
        "rules": "open",
        "description": "Extensions are always sliced by (at least) url",
        "discriminator": [ {
          "path": "url",
          "type": "value"
        } ]
      },
      "type": [ {
        "code": "Extension"
      } ],
      "alias": [ "extensions", "user content" ],
      "max": "*",
      "id": "Extension.extension:modelCharacteristic.extension:variable.extension:valueRange.extension",
      "comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
      "base": {
        "max": "*",
        "min": 0,
        "path": "Element.extension"
      },
      "isSummary": false
    }, {
      "path": "Extension.extension.extension.extension.url",
      "min": 1,
      "definition": "Source of the definition for the extension code - a logical name or a URL.",
      "isModifier": false,
      "short": "identifies the meaning of the extension",
      "fixedUri": "valueRange",
      "mapping": [ {
        "map": "N/A",
        "identity": "rim"
      } ],
      "type": [ {
        "code": "http://hl7.org/fhirpath/System.String",
        "extension": [ {
          "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
          "valueUrl": "uri"
        } ]
      } ],
      "representation": [ "xmlAttr" ],
      "max": "1",
      "id": "Extension.extension:modelCharacteristic.extension:variable.extension:valueRange.url",
      "comment": "The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.",
      "base": {
        "max": "1",
        "min": 1,
        "path": "Extension.url"
      },
      "isSummary": false
    }, {
      "constraint": [ {
        "key": "ele-1",
        "human": "All FHIR elements must have a @value or children",
        "xpath": "@value|f:*|h:div",
        "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1",
        "severity": "error",
        "expression": "hasValue() or (children().count() > id.count())"
      } ],
      "path": "Extension.extension.extension.extension.value[x]",
      "min": 0,
      "definition": "Range of values for grouping of ordinal or polychotomous variables.",
      "isModifier": false,
      "short": "Range of values for grouping of ordinal or polychotomous variables",
      "mapping": [ {
        "map": "N/A",
        "identity": "rim"
      } ],
      "type": [ {
        "code": "Range"
      } ],
      "max": "1",
      "id": "Extension.extension:modelCharacteristic.extension:variable.extension:valueRange.value[x]",
      "base": {
        "max": "1",
        "min": 0,
        "path": "Extension.value[x]"
      },
      "isSummary": false
    }, {
      "path": "Extension.extension.extension.url",
      "min": 1,
      "definition": "Source of the definition for the extension code - a logical name or a URL.",
      "isModifier": false,
      "short": "identifies the meaning of the extension",
      "fixedUri": "variable",
      "mapping": [ {
        "map": "N/A",
        "identity": "rim"
      } ],
      "type": [ {
        "code": "http://hl7.org/fhirpath/System.String",
        "extension": [ {
          "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
          "valueUrl": "uri"
        } ]
      } ],
      "representation": [ "xmlAttr" ],
      "max": "1",
      "id": "Extension.extension:modelCharacteristic.extension:variable.url",
      "comment": "The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.",
      "base": {
        "max": "1",
        "min": 1,
        "path": "Extension.url"
      },
      "isSummary": false
    }, {
      "constraint": [ {
        "key": "ele-1",
        "human": "All FHIR elements must have a @value or children",
        "xpath": "@value|f:*|h:div",
        "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1",
        "severity": "error",
        "expression": "hasValue() or (children().count() > id.count())"
      } ],
      "path": "Extension.extension.extension.value[x]",
      "min": 0,
      "definition": "Value of extension - must be one of a constrained set of the data types (see [Extensibility](http://hl7.org/fhir/R4/extensibility.html) for a list).",
      "isModifier": false,
      "short": "Value of extension",
      "mapping": [ {
        "map": "N/A",
        "identity": "rim"
      } ],
      "type": [ {
        "code": "base64Binary"
      }, {
        "code": "boolean"
      }, {
        "code": "canonical"
      }, {
        "code": "code"
      }, {
        "code": "date"
      }, {
        "code": "dateTime"
      }, {
        "code": "decimal"
      }, {
        "code": "id"
      }, {
        "code": "instant"
      }, {
        "code": "integer"
      }, {
        "code": "markdown"
      }, {
        "code": "oid"
      }, {
        "code": "positiveInt"
      }, {
        "code": "string"
      }, {
        "code": "time"
      }, {
        "code": "unsignedInt"
      }, {
        "code": "uri"
      }, {
        "code": "url"
      }, {
        "code": "uuid"
      }, {
        "code": "Address"
      }, {
        "code": "Age"
      }, {
        "code": "Annotation"
      }, {
        "code": "Attachment"
      }, {
        "code": "CodeableConcept"
      }, {
        "code": "Coding"
      }, {
        "code": "ContactPoint"
      }, {
        "code": "Count"
      }, {
        "code": "Distance"
      }, {
        "code": "Duration"
      }, {
        "code": "HumanName"
      }, {
        "code": "Identifier"
      }, {
        "code": "Money"
      }, {
        "code": "Period"
      }, {
        "code": "Quantity"
      }, {
        "code": "Range"
      }, {
        "code": "Ratio"
      }, {
        "code": "Reference"
      }, {
        "code": "SampledData"
      }, {
        "code": "Signature"
      }, {
        "code": "Timing"
      }, {
        "code": "ContactDetail"
      }, {
        "code": "Contributor"
      }, {
        "code": "DataRequirement"
      }, {
        "code": "Expression"
      }, {
        "code": "ParameterDefinition"
      }, {
        "code": "RelatedArtifact"
      }, {
        "code": "TriggerDefinition"
      }, {
        "code": "UsageContext"
      }, {
        "code": "Dosage"
      }, {
        "code": "Meta"
      } ],
      "max": "0",
      "id": "Extension.extension:modelCharacteristic.extension:variable.value[x]",
      "base": {
        "max": "1",
        "min": 0,
        "path": "Extension.value[x]"
      },
      "isSummary": false
    }, {
      "constraint": [ {
        "key": "ele-1",
        "human": "All FHIR elements must have a @value or children",
        "xpath": "@value|f:*|h:div",
        "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1",
        "severity": "error",
        "expression": "hasValue() or (children().count() > id.count())"
      }, {
        "key": "ext-1",
        "human": "Must have either extensions or value[x], not both",
        "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
        "source": "http://hl7.org/fhir/StructureDefinition/Extension|4.0.1",
        "severity": "error",
        "expression": "extension.exists() != value.exists()"
      } ],
      "path": "Extension.extension.extension",
      "requirements": "Element `Evidence.statistic.modelCharacteristic.attributeEstimate` is part of an existing definition because parent element `Evidence.statistic.modelCharacteristic` requires a cross-version extension.\nElement `Evidence.statistic.modelCharacteristic.attributeEstimate` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.modelCharacteristic.attributeEstimate` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
      "min": 0,
      "definition": "R4B: `Evidence.statistic.modelCharacteristic.attributeEstimate` (new:Evidence.statistic.attributeEstimate)",
      "isModifier": false,
      "short": "R4B: An attribute of the statistic used as a model characteristic (new)",
      "type": [ {
        "code": "Extension"
      } ],
      "sliceName": "attributeEstimate",
      "max": "*",
      "id": "Extension.extension:modelCharacteristic.extension:attributeEstimate",
      "comment": "Element `Evidence.statistic.modelCharacteristic.attributeEstimate` is part of an existing definition because parent element `Evidence.statistic.modelCharacteristic` requires a cross-version extension.\nElement `Evidence.statistic.modelCharacteristic.attributeEstimate` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.modelCharacteristic.attributeEstimate` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
      "base": {
        "max": "*",
        "min": 0,
        "path": "Element.extension"
      },
      "isSummary": false
    }, {
      "path": "Extension.extension.extension.id",
      "min": 0,
      "definition": "Unique id for the element within a resource (for internal references). This may be any string value that does not contain spaces.",
      "isModifier": false,
      "short": "Unique id for inter-element referencing",
      "mapping": [ {
        "map": "n/a",
        "identity": "rim"
      } ],
      "type": [ {
        "code": "http://hl7.org/fhirpath/System.String",
        "extension": [ {
          "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
          "valueUrl": "string"
        } ]
      } ],
      "representation": [ "xmlAttr" ],
      "max": "1",
      "id": "Extension.extension:modelCharacteristic.extension:attributeEstimate.id",
      "base": {
        "max": "1",
        "min": 0,
        "path": "Element.id"
      },
      "isSummary": false
    }, {
      "constraint": [ {
        "key": "ele-1",
        "human": "All FHIR elements must have a @value or children",
        "xpath": "@value|f:*|h:div",
        "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1",
        "severity": "error",
        "expression": "hasValue() or (children().count() > id.count())"
      }, {
        "key": "ext-1",
        "human": "Must have either extensions or value[x], not both",
        "xpath": "exists(f:extension)!=exists(f:*[starts-with(local-name(.), \"value\")])",
        "source": "http://hl7.org/fhir/StructureDefinition/Extension|4.0.1",
        "severity": "error",
        "expression": "extension.exists() != value.exists()"
      } ],
      "path": "Extension.extension.extension.extension",
      "min": 0,
      "definition": "May be used to represent additional information that is not part of the basic definition of the element. To make the use of extensions safe and manageable, there is a strict set of governance  applied to the definition and use of extensions. Though any implementer can define an extension, there is a set of requirements that SHALL be met as part of the definition of the extension.",
      "isModifier": false,
      "short": "Additional content defined by implementations",
      "mapping": [ {
        "map": "n/a",
        "identity": "rim"
      } ],
      "slicing": {
        "rules": "open",
        "description": "Extensions are always sliced by (at least) url",
        "discriminator": [ {
          "path": "url",
          "type": "value"
        } ]
      },
      "type": [ {
        "code": "Extension"
      } ],
      "alias": [ "extensions", "user content" ],
      "max": "*",
      "id": "Extension.extension:modelCharacteristic.extension:attributeEstimate.extension",
      "comment": "There can be no stigma associated with the use of extensions by any application, project, or standard - regardless of the institution or jurisdiction that uses or defines the extensions.  The use of extensions is what allows the FHIR specification to retain a core level of simplicity for everyone.",
      "base": {
        "max": "*",
        "min": 0,
        "path": "Element.extension"
      },
      "isSummary": false
    }, {
      "path": "Extension.extension.extension.url",
      "min": 1,
      "definition": "Source of the definition for the extension code - a logical name or a URL.",
      "isModifier": false,
      "short": "identifies the meaning of the extension",
      "fixedUri": "http://hl7.org/fhir/4.3/StructureDefinition/extension-Evidence.statistic.attributeEstimate",
      "mapping": [ {
        "map": "N/A",
        "identity": "rim"
      } ],
      "type": [ {
        "code": "http://hl7.org/fhirpath/System.String",
        "extension": [ {
          "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
          "valueUrl": "uri"
        } ]
      } ],
      "representation": [ "xmlAttr" ],
      "max": "1",
      "id": "Extension.extension:modelCharacteristic.extension:attributeEstimate.url",
      "comment": "The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.",
      "base": {
        "max": "1",
        "min": 1,
        "path": "Extension.url"
      },
      "isSummary": false
    }, {
      "constraint": [ {
        "key": "ele-1",
        "human": "All FHIR elements must have a @value or children",
        "xpath": "@value|f:*|h:div",
        "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1",
        "severity": "error",
        "expression": "hasValue() or (children().count() > id.count())"
      } ],
      "path": "Extension.extension.extension.value[x]",
      "min": 0,
      "definition": "Value of extension - must be one of a constrained set of the data types (see [Extensibility](http://hl7.org/fhir/R4/extensibility.html) for a list).",
      "isModifier": false,
      "short": "Value of extension",
      "mapping": [ {
        "map": "N/A",
        "identity": "rim"
      } ],
      "type": [ {
        "code": "base64Binary"
      }, {
        "code": "boolean"
      }, {
        "code": "canonical"
      }, {
        "code": "code"
      }, {
        "code": "date"
      }, {
        "code": "dateTime"
      }, {
        "code": "decimal"
      }, {
        "code": "id"
      }, {
        "code": "instant"
      }, {
        "code": "integer"
      }, {
        "code": "markdown"
      }, {
        "code": "oid"
      }, {
        "code": "positiveInt"
      }, {
        "code": "string"
      }, {
        "code": "time"
      }, {
        "code": "unsignedInt"
      }, {
        "code": "uri"
      }, {
        "code": "url"
      }, {
        "code": "uuid"
      }, {
        "code": "Address"
      }, {
        "code": "Age"
      }, {
        "code": "Annotation"
      }, {
        "code": "Attachment"
      }, {
        "code": "CodeableConcept"
      }, {
        "code": "Coding"
      }, {
        "code": "ContactPoint"
      }, {
        "code": "Count"
      }, {
        "code": "Distance"
      }, {
        "code": "Duration"
      }, {
        "code": "HumanName"
      }, {
        "code": "Identifier"
      }, {
        "code": "Money"
      }, {
        "code": "Period"
      }, {
        "code": "Quantity"
      }, {
        "code": "Range"
      }, {
        "code": "Ratio"
      }, {
        "code": "Reference"
      }, {
        "code": "SampledData"
      }, {
        "code": "Signature"
      }, {
        "code": "Timing"
      }, {
        "code": "ContactDetail"
      }, {
        "code": "Contributor"
      }, {
        "code": "DataRequirement"
      }, {
        "code": "Expression"
      }, {
        "code": "ParameterDefinition"
      }, {
        "code": "RelatedArtifact"
      }, {
        "code": "TriggerDefinition"
      }, {
        "code": "UsageContext"
      }, {
        "code": "Dosage"
      }, {
        "code": "Meta"
      } ],
      "max": "0",
      "id": "Extension.extension:modelCharacteristic.extension:attributeEstimate.value[x]",
      "base": {
        "max": "1",
        "min": 0,
        "path": "Extension.value[x]"
      },
      "isSummary": false
    }, {
      "path": "Extension.extension.url",
      "min": 1,
      "definition": "Source of the definition for the extension code - a logical name or a URL.",
      "isModifier": false,
      "short": "identifies the meaning of the extension",
      "fixedUri": "modelCharacteristic",
      "mapping": [ {
        "map": "N/A",
        "identity": "rim"
      } ],
      "type": [ {
        "code": "http://hl7.org/fhirpath/System.String",
        "extension": [ {
          "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
          "valueUrl": "uri"
        } ]
      } ],
      "representation": [ "xmlAttr" ],
      "max": "1",
      "id": "Extension.extension:modelCharacteristic.url",
      "comment": "The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.",
      "base": {
        "max": "1",
        "min": 1,
        "path": "Extension.url"
      },
      "isSummary": false
    }, {
      "constraint": [ {
        "key": "ele-1",
        "human": "All FHIR elements must have a @value or children",
        "xpath": "@value|f:*|h:div",
        "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1",
        "severity": "error",
        "expression": "hasValue() or (children().count() > id.count())"
      } ],
      "path": "Extension.extension.value[x]",
      "min": 0,
      "definition": "Value of extension - must be one of a constrained set of the data types (see [Extensibility](http://hl7.org/fhir/R4/extensibility.html) for a list).",
      "isModifier": false,
      "short": "Value of extension",
      "mapping": [ {
        "map": "N/A",
        "identity": "rim"
      } ],
      "type": [ {
        "code": "base64Binary"
      }, {
        "code": "boolean"
      }, {
        "code": "canonical"
      }, {
        "code": "code"
      }, {
        "code": "date"
      }, {
        "code": "dateTime"
      }, {
        "code": "decimal"
      }, {
        "code": "id"
      }, {
        "code": "instant"
      }, {
        "code": "integer"
      }, {
        "code": "markdown"
      }, {
        "code": "oid"
      }, {
        "code": "positiveInt"
      }, {
        "code": "string"
      }, {
        "code": "time"
      }, {
        "code": "unsignedInt"
      }, {
        "code": "uri"
      }, {
        "code": "url"
      }, {
        "code": "uuid"
      }, {
        "code": "Address"
      }, {
        "code": "Age"
      }, {
        "code": "Annotation"
      }, {
        "code": "Attachment"
      }, {
        "code": "CodeableConcept"
      }, {
        "code": "Coding"
      }, {
        "code": "ContactPoint"
      }, {
        "code": "Count"
      }, {
        "code": "Distance"
      }, {
        "code": "Duration"
      }, {
        "code": "HumanName"
      }, {
        "code": "Identifier"
      }, {
        "code": "Money"
      }, {
        "code": "Period"
      }, {
        "code": "Quantity"
      }, {
        "code": "Range"
      }, {
        "code": "Ratio"
      }, {
        "code": "Reference"
      }, {
        "code": "SampledData"
      }, {
        "code": "Signature"
      }, {
        "code": "Timing"
      }, {
        "code": "ContactDetail"
      }, {
        "code": "Contributor"
      }, {
        "code": "DataRequirement"
      }, {
        "code": "Expression"
      }, {
        "code": "ParameterDefinition"
      }, {
        "code": "RelatedArtifact"
      }, {
        "code": "TriggerDefinition"
      }, {
        "code": "UsageContext"
      }, {
        "code": "Dosage"
      }, {
        "code": "Meta"
      } ],
      "max": "0",
      "id": "Extension.extension:modelCharacteristic.value[x]",
      "base": {
        "max": "1",
        "min": 0,
        "path": "Extension.value[x]"
      },
      "isSummary": false
    }, {
      "path": "Extension.url",
      "min": 1,
      "definition": "Source of the definition for the extension code - a logical name or a URL.",
      "isModifier": false,
      "short": "identifies the meaning of the extension",
      "fixedUri": "http://hl7.org/fhir/4.3/StructureDefinition/extension-Evidence.statistic",
      "mapping": [ {
        "map": "N/A",
        "identity": "rim"
      } ],
      "type": [ {
        "code": "http://hl7.org/fhirpath/System.String",
        "extension": [ {
          "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-fhir-type",
          "valueUrl": "uri"
        } ]
      } ],
      "representation": [ "xmlAttr" ],
      "max": "1",
      "id": "Extension.url",
      "comment": "The definition may point directly to a computable or human-readable definition of the extensibility codes, or it may be a logical URI as declared in some other specification. The definition SHALL be a URI for the Structure Definition defining the extension.",
      "base": {
        "max": "1",
        "min": 1,
        "path": "Extension.url"
      },
      "isSummary": false
    }, {
      "constraint": [ {
        "key": "ele-1",
        "human": "All FHIR elements must have a @value or children",
        "xpath": "@value|f:*|h:div",
        "source": "http://hl7.org/fhir/StructureDefinition/Element|4.0.1",
        "severity": "error",
        "expression": "hasValue() or (children().count() > id.count())"
      } ],
      "path": "Extension.value[x]",
      "min": 0,
      "definition": "Value of extension - must be one of a constrained set of the data types (see [Extensibility](http://hl7.org/fhir/R4/extensibility.html) for a list).",
      "isModifier": false,
      "short": "Value of extension",
      "mapping": [ {
        "map": "N/A",
        "identity": "rim"
      } ],
      "type": [ {
        "code": "base64Binary"
      }, {
        "code": "boolean"
      }, {
        "code": "canonical"
      }, {
        "code": "code"
      }, {
        "code": "date"
      }, {
        "code": "dateTime"
      }, {
        "code": "decimal"
      }, {
        "code": "id"
      }, {
        "code": "instant"
      }, {
        "code": "integer"
      }, {
        "code": "markdown"
      }, {
        "code": "oid"
      }, {
        "code": "positiveInt"
      }, {
        "code": "string"
      }, {
        "code": "time"
      }, {
        "code": "unsignedInt"
      }, {
        "code": "uri"
      }, {
        "code": "url"
      }, {
        "code": "uuid"
      }, {
        "code": "Address"
      }, {
        "code": "Age"
      }, {
        "code": "Annotation"
      }, {
        "code": "Attachment"
      }, {
        "code": "CodeableConcept"
      }, {
        "code": "Coding"
      }, {
        "code": "ContactPoint"
      }, {
        "code": "Count"
      }, {
        "code": "Distance"
      }, {
        "code": "Duration"
      }, {
        "code": "HumanName"
      }, {
        "code": "Identifier"
      }, {
        "code": "Money"
      }, {
        "code": "Period"
      }, {
        "code": "Quantity"
      }, {
        "code": "Range"
      }, {
        "code": "Ratio"
      }, {
        "code": "Reference"
      }, {
        "code": "SampledData"
      }, {
        "code": "Signature"
      }, {
        "code": "Timing"
      }, {
        "code": "ContactDetail"
      }, {
        "code": "Contributor"
      }, {
        "code": "DataRequirement"
      }, {
        "code": "Expression"
      }, {
        "code": "ParameterDefinition"
      }, {
        "code": "RelatedArtifact"
      }, {
        "code": "TriggerDefinition"
      }, {
        "code": "UsageContext"
      }, {
        "code": "Dosage"
      }, {
        "code": "Meta"
      } ],
      "max": "0",
      "id": "Extension.value[x]",
      "base": {
        "max": "1",
        "min": 0,
        "path": "Extension.value[x]"
      },
      "isSummary": false
    } ],
    "extension": [ {
      "url": "http://hl7.org/fhir/tools/StructureDefinition/snapshot-base-version",
      "valueString": "4.0.1"
    } ]
  },
  "status": "active",
  "id": "1ceed2a6-85c0-4019-a664-5c15241697cc",
  "kind": "complex-type",
  "url": "http://hl7.org/fhir/4.3/StructureDefinition/extension-Evidence.statistic",
  "context": [ {
    "type": "element",
    "expression": "Evidence"
  } ],
  "version": "0.1.0",
  "differential": {
    "element": [ {
      "path": "Extension",
      "min": 0,
      "definition": "R4B: `Evidence.statistic` (new:BackboneElement)",
      "isModifier": false,
      "short": "R4B: Values and parameters for a single statistic (new)",
      "max": "*",
      "id": "Extension",
      "comment": "Element `Evidence.statistic` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
      "base": {
        "max": "*",
        "min": 0,
        "path": "Extension"
      }
    }, {
      "id": "Extension.extension",
      "max": "*",
      "min": 0,
      "base": {
        "max": "*",
        "min": 0,
        "path": "Extension.extension"
      },
      "path": "Extension.extension",
      "slicing": {
        "rules": "open",
        "ordered": false,
        "discriminator": [ {
          "path": "url",
          "type": "value"
        } ]
      }
    }, {
      "path": "Extension.extension",
      "requirements": "Element `Evidence.statistic.description` is part of an existing definition because parent element `Evidence.statistic` requires a cross-version extension.\nElement `Evidence.statistic.description` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.description` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
      "min": 0,
      "definition": "R4B: `Evidence.statistic.description` (new:string)",
      "short": "R4B: Description of content (new)",
      "sliceName": "description",
      "max": "1",
      "id": "Extension.extension:description",
      "comment": "Element `Evidence.statistic.description` is part of an existing definition because parent element `Evidence.statistic` requires a cross-version extension.\nElement `Evidence.statistic.description` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.description` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
      "base": {
        "max": "*",
        "min": 0,
        "path": "Extension.extension"
      }
    }, {
      "id": "Extension.extension:description.url",
      "max": "1",
      "min": 1,
      "base": {
        "max": "1",
        "min": 1,
        "path": "Extension.url"
      },
      "path": "Extension.extension.url",
      "fixedUri": "description"
    }, {
      "id": "Extension.extension:description.value[x]",
      "max": "1",
      "min": 0,
      "base": {
        "max": "1",
        "min": 0,
        "path": "Extension.value[x]"
      },
      "path": "Extension.extension.value[x]",
      "type": [ {
        "code": "string"
      } ],
      "short": "Description of content",
      "definition": "A description of the content value of the statistic."
    }, {
      "path": "Extension.extension",
      "requirements": "Element `Evidence.statistic.note` is part of an existing definition because parent element `Evidence.statistic` requires a cross-version extension.\nElement `Evidence.statistic.note` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.note` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
      "min": 0,
      "definition": "R4B: `Evidence.statistic.note` (new:Annotation)",
      "short": "R4B: Footnotes and/or explanatory notes (new)",
      "sliceName": "note",
      "max": "*",
      "id": "Extension.extension:note",
      "comment": "Element `Evidence.statistic.note` is part of an existing definition because parent element `Evidence.statistic` requires a cross-version extension.\nElement `Evidence.statistic.note` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.note` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
      "base": {
        "max": "*",
        "min": 0,
        "path": "Extension.extension"
      }
    }, {
      "id": "Extension.extension:note.url",
      "max": "1",
      "min": 1,
      "base": {
        "max": "1",
        "min": 1,
        "path": "Extension.url"
      },
      "path": "Extension.extension.url",
      "fixedUri": "note"
    }, {
      "id": "Extension.extension:note.value[x]",
      "max": "1",
      "min": 0,
      "base": {
        "max": "1",
        "min": 0,
        "path": "Extension.value[x]"
      },
      "path": "Extension.extension.value[x]",
      "type": [ {
        "code": "Annotation"
      } ],
      "short": "Footnotes and/or explanatory notes",
      "definition": "Footnotes and/or explanatory notes."
    }, {
      "path": "Extension.extension",
      "requirements": "Element `Evidence.statistic.statisticType` is part of an existing definition because parent element `Evidence.statistic` requires a cross-version extension.\nElement `Evidence.statistic.statisticType` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.statisticType` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
      "min": 0,
      "definition": "R4B: `Evidence.statistic.statisticType` (new:CodeableConcept)",
      "short": "R4B: Type of statistic, eg relative risk (new)",
      "sliceName": "statisticType",
      "max": "1",
      "id": "Extension.extension:statisticType",
      "comment": "Element `Evidence.statistic.statisticType` is part of an existing definition because parent element `Evidence.statistic` requires a cross-version extension.\nElement `Evidence.statistic.statisticType` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.statisticType` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
      "base": {
        "max": "*",
        "min": 0,
        "path": "Extension.extension"
      }
    }, {
      "id": "Extension.extension:statisticType.url",
      "max": "1",
      "min": 1,
      "base": {
        "max": "1",
        "min": 1,
        "path": "Extension.url"
      },
      "path": "Extension.extension.url",
      "fixedUri": "statisticType"
    }, {
      "path": "Extension.extension.value[x]",
      "min": 0,
      "definition": "Type of statistic, eg relative risk.",
      "short": "Type of statistic, eg relative risk",
      "type": [ {
        "code": "CodeableConcept"
      } ],
      "binding": {
        "strength": "extensible",
        "valueSet": "http://hl7.org/fhir/uv/xver/ValueSet/R4B-statistic-type-for-R4|0.1.0"
      },
      "max": "1",
      "id": "Extension.extension:statisticType.value[x]",
      "base": {
        "max": "1",
        "min": 0,
        "path": "Extension.value[x]"
      }
    }, {
      "path": "Extension.extension",
      "requirements": "Element `Evidence.statistic.category` is part of an existing definition because parent element `Evidence.statistic` requires a cross-version extension.\nElement `Evidence.statistic.category` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.category` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
      "min": 0,
      "definition": "R4B: `Evidence.statistic.category` (new:CodeableConcept)",
      "short": "R4B: Associated category for categorical variable (new)",
      "sliceName": "category",
      "max": "1",
      "id": "Extension.extension:category",
      "comment": "Element `Evidence.statistic.category` is part of an existing definition because parent element `Evidence.statistic` requires a cross-version extension.\nElement `Evidence.statistic.category` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.category` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).\nSimple strings can be used for descriptive purposes. Exact matching to EvidenceVariable.category.name for the Evidence.variableDefinition[variableRole=measuredVariable].observed=Reference(EvidenceVariable) could facilitate validation within datasets.",
      "base": {
        "max": "*",
        "min": 0,
        "path": "Extension.extension"
      }
    }, {
      "id": "Extension.extension:category.url",
      "max": "1",
      "min": 1,
      "base": {
        "max": "1",
        "min": 1,
        "path": "Extension.url"
      },
      "path": "Extension.extension.url",
      "fixedUri": "category"
    }, {
      "path": "Extension.extension.value[x]",
      "min": 0,
      "definition": "When the measured variable is handled categorically, the category element is used to define which category the statistic is reporting.",
      "short": "Associated category for categorical variable",
      "type": [ {
        "code": "CodeableConcept"
      } ],
      "max": "1",
      "id": "Extension.extension:category.value[x]",
      "comment": "Simple strings can be used for descriptive purposes. Exact matching to EvidenceVariable.category.name for the Evidence.variableDefinition[variableRole=measuredVariable].observed=Reference(EvidenceVariable) could facilitate validation within datasets.",
      "base": {
        "max": "1",
        "min": 0,
        "path": "Extension.value[x]"
      }
    }, {
      "path": "Extension.extension",
      "requirements": "Element `Evidence.statistic.quantity` is part of an existing definition because parent element `Evidence.statistic` requires a cross-version extension.\nElement `Evidence.statistic.quantity` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.quantity` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
      "min": 0,
      "definition": "R4B: `Evidence.statistic.quantity` (new:Quantity)",
      "short": "R4B: Statistic value (new)",
      "sliceName": "quantity",
      "max": "1",
      "id": "Extension.extension:quantity",
      "comment": "Element `Evidence.statistic.quantity` is part of an existing definition because parent element `Evidence.statistic` requires a cross-version extension.\nElement `Evidence.statistic.quantity` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.quantity` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
      "base": {
        "max": "*",
        "min": 0,
        "path": "Extension.extension"
      }
    }, {
      "id": "Extension.extension:quantity.url",
      "max": "1",
      "min": 1,
      "base": {
        "max": "1",
        "min": 1,
        "path": "Extension.url"
      },
      "path": "Extension.extension.url",
      "fixedUri": "quantity"
    }, {
      "id": "Extension.extension:quantity.value[x]",
      "max": "1",
      "min": 0,
      "base": {
        "max": "1",
        "min": 0,
        "path": "Extension.value[x]"
      },
      "path": "Extension.extension.value[x]",
      "type": [ {
        "code": "Quantity"
      } ],
      "short": "Statistic value",
      "definition": "Statistic value."
    }, {
      "path": "Extension.extension",
      "requirements": "Element `Evidence.statistic.numberOfEvents` is part of an existing definition because parent element `Evidence.statistic` requires a cross-version extension.\nElement `Evidence.statistic.numberOfEvents` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.numberOfEvents` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
      "min": 0,
      "definition": "R4B: `Evidence.statistic.numberOfEvents` (new:unsignedInt)",
      "short": "R4B: The number of events associated with the statistic (new)",
      "sliceName": "numberOfEvents",
      "max": "1",
      "id": "Extension.extension:numberOfEvents",
      "comment": "Element `Evidence.statistic.numberOfEvents` is part of an existing definition because parent element `Evidence.statistic` requires a cross-version extension.\nElement `Evidence.statistic.numberOfEvents` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.numberOfEvents` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).\nWhen the number of events is the statistic, use Evidence.statistic.quantity and set Evidence.statistic.type.coding.code=C25463 and Evidence.statistic.type.coding.display=Count. When the statistic is an Event Rate (where individual participants may have 2 or more events), use Evidence.statistic.numberOfEvents to record the total number of events rather than the number of participants with events.",
      "base": {
        "max": "*",
        "min": 0,
        "path": "Extension.extension"
      }
    }, {
      "id": "Extension.extension:numberOfEvents.url",
      "max": "1",
      "min": 1,
      "base": {
        "max": "1",
        "min": 1,
        "path": "Extension.url"
      },
      "path": "Extension.extension.url",
      "fixedUri": "numberOfEvents"
    }, {
      "path": "Extension.extension.value[x]",
      "min": 0,
      "definition": "The number of events associated with the statistic, where the unit of analysis is different from numberAffected, sampleSize.knownDataCount and sampleSize.numberOfParticipants.",
      "short": "The number of events associated with the statistic",
      "type": [ {
        "code": "unsignedInt"
      } ],
      "max": "1",
      "id": "Extension.extension:numberOfEvents.value[x]",
      "comment": "When the number of events is the statistic, use Evidence.statistic.quantity and set Evidence.statistic.type.coding.code=C25463 and Evidence.statistic.type.coding.display=Count. When the statistic is an Event Rate (where individual participants may have 2 or more events), use Evidence.statistic.numberOfEvents to record the total number of events rather than the number of participants with events.",
      "base": {
        "max": "1",
        "min": 0,
        "path": "Extension.value[x]"
      }
    }, {
      "path": "Extension.extension",
      "requirements": "Element `Evidence.statistic.numberAffected` is part of an existing definition because parent element `Evidence.statistic` requires a cross-version extension.\nElement `Evidence.statistic.numberAffected` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.numberAffected` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
      "min": 0,
      "definition": "R4B: `Evidence.statistic.numberAffected` (new:unsignedInt)",
      "short": "R4B: The number of participants affected (new)",
      "sliceName": "numberAffected",
      "max": "1",
      "id": "Extension.extension:numberAffected",
      "comment": "Element `Evidence.statistic.numberAffected` is part of an existing definition because parent element `Evidence.statistic` requires a cross-version extension.\nElement `Evidence.statistic.numberAffected` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.numberAffected` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).\nWhen the number affected is the statistic, use Evidence.statistic.quantity and set Evidence.statistic.type.coding.code=C25463 and Evidence.statistic.type.coding.display=Count. When the statistic is a Proportion, use Evidence.statistic.numberAffected and enter an integer as the value. When the statistic is an Event Rate (where individual participants may have 2 or more events), use Evidence.statistic.numberAffected to record the number of participants with events rather than the total number of events.",
      "base": {
        "max": "*",
        "min": 0,
        "path": "Extension.extension"
      }
    }, {
      "id": "Extension.extension:numberAffected.url",
      "max": "1",
      "min": 1,
      "base": {
        "max": "1",
        "min": 1,
        "path": "Extension.url"
      },
      "path": "Extension.extension.url",
      "fixedUri": "numberAffected"
    }, {
      "path": "Extension.extension.value[x]",
      "min": 0,
      "definition": "The number of participants affected where the unit of analysis is the same as sampleSize.knownDataCount and sampleSize.numberOfParticipants.",
      "short": "The number of participants affected",
      "type": [ {
        "code": "unsignedInt"
      } ],
      "max": "1",
      "id": "Extension.extension:numberAffected.value[x]",
      "comment": "When the number affected is the statistic, use Evidence.statistic.quantity and set Evidence.statistic.type.coding.code=C25463 and Evidence.statistic.type.coding.display=Count. When the statistic is a Proportion, use Evidence.statistic.numberAffected and enter an integer as the value. When the statistic is an Event Rate (where individual participants may have 2 or more events), use Evidence.statistic.numberAffected to record the number of participants with events rather than the total number of events.",
      "base": {
        "max": "1",
        "min": 0,
        "path": "Extension.value[x]"
      }
    }, {
      "path": "Extension.extension",
      "requirements": "Element `Evidence.statistic.sampleSize` is part of an existing definition because parent element `Evidence.statistic` requires a cross-version extension.\nElement `Evidence.statistic.sampleSize` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.sampleSize` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
      "min": 0,
      "definition": "R4B: `Evidence.statistic.sampleSize` (new:BackboneElement)",
      "short": "R4B: Number of samples in the statistic (new)",
      "sliceName": "sampleSize",
      "max": "1",
      "id": "Extension.extension:sampleSize",
      "comment": "Element `Evidence.statistic.sampleSize` is part of an existing definition because parent element `Evidence.statistic` requires a cross-version extension.\nElement `Evidence.statistic.sampleSize` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.sampleSize` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
      "base": {
        "max": "*",
        "min": 0,
        "path": "Extension.extension"
      }
    }, {
      "id": "Extension.extension:sampleSize.extension",
      "max": "*",
      "min": 0,
      "base": {
        "max": "*",
        "min": 0,
        "path": "Extension.extension"
      },
      "path": "Extension.extension.extension",
      "slicing": {
        "rules": "open",
        "ordered": false,
        "discriminator": [ {
          "path": "url",
          "type": "value"
        } ]
      }
    }, {
      "path": "Extension.extension.extension",
      "requirements": "Element `Evidence.statistic.sampleSize.description` is part of an existing definition because parent element `Evidence.statistic.sampleSize` requires a cross-version extension.\nElement `Evidence.statistic.sampleSize.description` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.sampleSize.description` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
      "min": 0,
      "definition": "R4B: `Evidence.statistic.sampleSize.description` (new:string)",
      "short": "R4B: Textual description of sample size for statistic (new)",
      "sliceName": "description",
      "max": "1",
      "id": "Extension.extension:sampleSize.extension:description",
      "comment": "Element `Evidence.statistic.sampleSize.description` is part of an existing definition because parent element `Evidence.statistic.sampleSize` requires a cross-version extension.\nElement `Evidence.statistic.sampleSize.description` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.sampleSize.description` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
      "base": {
        "max": "*",
        "min": 0,
        "path": "Extension.extension"
      }
    }, {
      "id": "Extension.extension:sampleSize.extension:description.url",
      "max": "1",
      "min": 1,
      "base": {
        "max": "1",
        "min": 1,
        "path": "Extension.url"
      },
      "path": "Extension.extension.extension.url",
      "fixedUri": "description"
    }, {
      "id": "Extension.extension:sampleSize.extension:description.value[x]",
      "max": "1",
      "min": 0,
      "base": {
        "max": "1",
        "min": 0,
        "path": "Extension.value[x]"
      },
      "path": "Extension.extension.extension.value[x]",
      "type": [ {
        "code": "string"
      } ],
      "short": "Textual description of sample size for statistic",
      "definition": "Human-readable summary of population sample size."
    }, {
      "path": "Extension.extension.extension",
      "requirements": "Element `Evidence.statistic.sampleSize.note` is part of an existing definition because parent element `Evidence.statistic.sampleSize` requires a cross-version extension.\nElement `Evidence.statistic.sampleSize.note` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.sampleSize.note` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
      "min": 0,
      "definition": "R4B: `Evidence.statistic.sampleSize.note` (new:Annotation)",
      "short": "R4B: Footnote or explanatory note about the sample size (new)",
      "sliceName": "note",
      "max": "*",
      "id": "Extension.extension:sampleSize.extension:note",
      "comment": "Element `Evidence.statistic.sampleSize.note` is part of an existing definition because parent element `Evidence.statistic.sampleSize` requires a cross-version extension.\nElement `Evidence.statistic.sampleSize.note` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.sampleSize.note` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
      "base": {
        "max": "*",
        "min": 0,
        "path": "Extension.extension"
      }
    }, {
      "id": "Extension.extension:sampleSize.extension:note.url",
      "max": "1",
      "min": 1,
      "base": {
        "max": "1",
        "min": 1,
        "path": "Extension.url"
      },
      "path": "Extension.extension.extension.url",
      "fixedUri": "note"
    }, {
      "id": "Extension.extension:sampleSize.extension:note.value[x]",
      "max": "1",
      "min": 0,
      "base": {
        "max": "1",
        "min": 0,
        "path": "Extension.value[x]"
      },
      "path": "Extension.extension.extension.value[x]",
      "type": [ {
        "code": "Annotation"
      } ],
      "short": "Footnote or explanatory note about the sample size",
      "definition": "Footnote or explanatory note about the sample size."
    }, {
      "path": "Extension.extension.extension",
      "requirements": "Element `Evidence.statistic.sampleSize.numberOfStudies` is part of an existing definition because parent element `Evidence.statistic.sampleSize` requires a cross-version extension.\nElement `Evidence.statistic.sampleSize.numberOfStudies` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.sampleSize.numberOfStudies` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
      "min": 0,
      "definition": "R4B: `Evidence.statistic.sampleSize.numberOfStudies` (new:unsignedInt)",
      "short": "R4B: Number of contributing studies (new)",
      "sliceName": "numberOfStudies",
      "max": "1",
      "id": "Extension.extension:sampleSize.extension:numberOfStudies",
      "comment": "Element `Evidence.statistic.sampleSize.numberOfStudies` is part of an existing definition because parent element `Evidence.statistic.sampleSize` requires a cross-version extension.\nElement `Evidence.statistic.sampleSize.numberOfStudies` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.sampleSize.numberOfStudies` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
      "base": {
        "max": "*",
        "min": 0,
        "path": "Extension.extension"
      }
    }, {
      "id": "Extension.extension:sampleSize.extension:numberOfStudies.url",
      "max": "1",
      "min": 1,
      "base": {
        "max": "1",
        "min": 1,
        "path": "Extension.url"
      },
      "path": "Extension.extension.extension.url",
      "fixedUri": "numberOfStudies"
    }, {
      "id": "Extension.extension:sampleSize.extension:numberOfStudies.value[x]",
      "max": "1",
      "min": 0,
      "base": {
        "max": "1",
        "min": 0,
        "path": "Extension.value[x]"
      },
      "path": "Extension.extension.extension.value[x]",
      "type": [ {
        "code": "unsignedInt"
      } ],
      "short": "Number of contributing studies",
      "definition": "Number of participants in the population."
    }, {
      "path": "Extension.extension.extension",
      "requirements": "Element `Evidence.statistic.sampleSize.numberOfParticipants` is part of an existing definition because parent element `Evidence.statistic.sampleSize` requires a cross-version extension.\nElement `Evidence.statistic.sampleSize.numberOfParticipants` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.sampleSize.numberOfParticipants` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
      "min": 0,
      "definition": "R4B: `Evidence.statistic.sampleSize.numberOfParticipants` (new:unsignedInt)",
      "short": "R4B: Cumulative number of participants (new)",
      "sliceName": "numberOfParticipants",
      "max": "1",
      "id": "Extension.extension:sampleSize.extension:numberOfParticipants",
      "comment": "Element `Evidence.statistic.sampleSize.numberOfParticipants` is part of an existing definition because parent element `Evidence.statistic.sampleSize` requires a cross-version extension.\nElement `Evidence.statistic.sampleSize.numberOfParticipants` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.sampleSize.numberOfParticipants` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
      "base": {
        "max": "*",
        "min": 0,
        "path": "Extension.extension"
      }
    }, {
      "id": "Extension.extension:sampleSize.extension:numberOfParticipants.url",
      "max": "1",
      "min": 1,
      "base": {
        "max": "1",
        "min": 1,
        "path": "Extension.url"
      },
      "path": "Extension.extension.extension.url",
      "fixedUri": "numberOfParticipants"
    }, {
      "id": "Extension.extension:sampleSize.extension:numberOfParticipants.value[x]",
      "max": "1",
      "min": 0,
      "base": {
        "max": "1",
        "min": 0,
        "path": "Extension.value[x]"
      },
      "path": "Extension.extension.extension.value[x]",
      "type": [ {
        "code": "unsignedInt"
      } ],
      "short": "Cumulative number of participants",
      "definition": "A human-readable string to clarify or explain concepts about the sample size."
    }, {
      "path": "Extension.extension.extension",
      "requirements": "Element `Evidence.statistic.sampleSize.knownDataCount` is part of an existing definition because parent element `Evidence.statistic.sampleSize` requires a cross-version extension.\nElement `Evidence.statistic.sampleSize.knownDataCount` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.sampleSize.knownDataCount` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
      "min": 0,
      "definition": "R4B: `Evidence.statistic.sampleSize.knownDataCount` (new:unsignedInt)",
      "short": "R4B: Number of participants with known results for measured variables (new)",
      "sliceName": "knownDataCount",
      "max": "1",
      "id": "Extension.extension:sampleSize.extension:knownDataCount",
      "comment": "Element `Evidence.statistic.sampleSize.knownDataCount` is part of an existing definition because parent element `Evidence.statistic.sampleSize` requires a cross-version extension.\nElement `Evidence.statistic.sampleSize.knownDataCount` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.sampleSize.knownDataCount` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
      "base": {
        "max": "*",
        "min": 0,
        "path": "Extension.extension"
      }
    }, {
      "id": "Extension.extension:sampleSize.extension:knownDataCount.url",
      "max": "1",
      "min": 1,
      "base": {
        "max": "1",
        "min": 1,
        "path": "Extension.url"
      },
      "path": "Extension.extension.extension.url",
      "fixedUri": "knownDataCount"
    }, {
      "id": "Extension.extension:sampleSize.extension:knownDataCount.value[x]",
      "max": "1",
      "min": 0,
      "base": {
        "max": "1",
        "min": 0,
        "path": "Extension.value[x]"
      },
      "path": "Extension.extension.extension.value[x]",
      "type": [ {
        "code": "unsignedInt"
      } ],
      "short": "Number of participants with known results for measured variables",
      "definition": "Number of participants with known results for measured variables."
    }, {
      "id": "Extension.extension:sampleSize.url",
      "max": "1",
      "min": 1,
      "base": {
        "max": "1",
        "min": 1,
        "path": "Extension.url"
      },
      "path": "Extension.extension.url",
      "fixedUri": "sampleSize"
    }, {
      "id": "Extension.extension:sampleSize.value[x]",
      "max": "0",
      "min": 0,
      "base": {
        "max": "1",
        "min": 0,
        "path": "Extension.value[x]"
      },
      "path": "Extension.extension.value[x]"
    }, {
      "path": "Extension.extension",
      "requirements": "Element `Evidence.statistic.attributeEstimate` is part of an existing definition because parent element `Evidence.statistic` requires a cross-version extension.\nElement `Evidence.statistic.attributeEstimate` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.attributeEstimate` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).\nCreating extension because element `Evidence.statistic.attributeEstimate` is a content reference and requires an extesion definition.",
      "min": 0,
      "definition": "R4B: `Evidence.statistic.attributeEstimate` (new:BackboneElement)",
      "short": "R4B: An attribute of the Statistic (new)",
      "sliceName": "attributeEstimate",
      "max": "*",
      "id": "Extension.extension:attributeEstimate",
      "comment": "Element `Evidence.statistic.attributeEstimate` is part of an existing definition because parent element `Evidence.statistic` requires a cross-version extension.\nElement `Evidence.statistic.attributeEstimate` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.attributeEstimate` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
      "base": {
        "max": "*",
        "min": 0,
        "path": "Extension.extension"
      }
    }, {
      "id": "Extension.extension:attributeEstimate.extension",
      "max": "*",
      "min": 0,
      "base": {
        "max": "*",
        "min": 0,
        "path": "Extension.extension"
      },
      "path": "Extension.extension.extension",
      "slicing": {
        "rules": "open",
        "ordered": false,
        "discriminator": [ {
          "path": "url",
          "type": "value"
        } ]
      }
    }, {
      "path": "Extension.extension.extension",
      "requirements": "Element `Evidence.statistic.attributeEstimate.description` is part of an existing definition because parent element `Evidence.statistic.attributeEstimate` requires a cross-version extension.\nElement `Evidence.statistic.attributeEstimate.description` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.attributeEstimate.description` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
      "min": 0,
      "definition": "R4B: `Evidence.statistic.attributeEstimate.description` (new:string)",
      "short": "R4B: Textual description of the attribute estimate (new)",
      "sliceName": "description",
      "max": "1",
      "id": "Extension.extension:attributeEstimate.extension:description",
      "comment": "Element `Evidence.statistic.attributeEstimate.description` is part of an existing definition because parent element `Evidence.statistic.attributeEstimate` requires a cross-version extension.\nElement `Evidence.statistic.attributeEstimate.description` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.attributeEstimate.description` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
      "base": {
        "max": "*",
        "min": 0,
        "path": "Extension.extension"
      }
    }, {
      "id": "Extension.extension:attributeEstimate.extension:description.url",
      "max": "1",
      "min": 1,
      "base": {
        "max": "1",
        "min": 1,
        "path": "Extension.url"
      },
      "path": "Extension.extension.extension.url",
      "fixedUri": "description"
    }, {
      "id": "Extension.extension:attributeEstimate.extension:description.value[x]",
      "max": "1",
      "min": 0,
      "base": {
        "max": "1",
        "min": 0,
        "path": "Extension.value[x]"
      },
      "path": "Extension.extension.extension.value[x]",
      "type": [ {
        "code": "string"
      } ],
      "short": "Textual description of the attribute estimate",
      "definition": "Human-readable summary of the estimate."
    }, {
      "path": "Extension.extension.extension",
      "requirements": "Element `Evidence.statistic.attributeEstimate.note` is part of an existing definition because parent element `Evidence.statistic.attributeEstimate` requires a cross-version extension.\nElement `Evidence.statistic.attributeEstimate.note` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.attributeEstimate.note` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
      "min": 0,
      "definition": "R4B: `Evidence.statistic.attributeEstimate.note` (new:Annotation)",
      "short": "R4B: Footnote or explanatory note about the estimate (new)",
      "sliceName": "note",
      "max": "*",
      "id": "Extension.extension:attributeEstimate.extension:note",
      "comment": "Element `Evidence.statistic.attributeEstimate.note` is part of an existing definition because parent element `Evidence.statistic.attributeEstimate` requires a cross-version extension.\nElement `Evidence.statistic.attributeEstimate.note` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.attributeEstimate.note` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
      "base": {
        "max": "*",
        "min": 0,
        "path": "Extension.extension"
      }
    }, {
      "id": "Extension.extension:attributeEstimate.extension:note.url",
      "max": "1",
      "min": 1,
      "base": {
        "max": "1",
        "min": 1,
        "path": "Extension.url"
      },
      "path": "Extension.extension.extension.url",
      "fixedUri": "note"
    }, {
      "id": "Extension.extension:attributeEstimate.extension:note.value[x]",
      "max": "1",
      "min": 0,
      "base": {
        "max": "1",
        "min": 0,
        "path": "Extension.value[x]"
      },
      "path": "Extension.extension.extension.value[x]",
      "type": [ {
        "code": "Annotation"
      } ],
      "short": "Footnote or explanatory note about the estimate",
      "definition": "Footnote or explanatory note about the estimate."
    }, {
      "path": "Extension.extension.extension",
      "requirements": "Element `Evidence.statistic.attributeEstimate.type` is part of an existing definition because parent element `Evidence.statistic.attributeEstimate` requires a cross-version extension.\nElement `Evidence.statistic.attributeEstimate.type` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.attributeEstimate.type` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
      "min": 0,
      "definition": "R4B: `Evidence.statistic.attributeEstimate.type` (new:CodeableConcept)",
      "short": "R4B: The type of attribute estimate, eg confidence interval or p value (new)",
      "sliceName": "type",
      "max": "1",
      "id": "Extension.extension:attributeEstimate.extension:type",
      "comment": "Element `Evidence.statistic.attributeEstimate.type` is part of an existing definition because parent element `Evidence.statistic.attributeEstimate` requires a cross-version extension.\nElement `Evidence.statistic.attributeEstimate.type` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.attributeEstimate.type` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
      "base": {
        "max": "*",
        "min": 0,
        "path": "Extension.extension"
      }
    }, {
      "id": "Extension.extension:attributeEstimate.extension:type.url",
      "max": "1",
      "min": 1,
      "base": {
        "max": "1",
        "min": 1,
        "path": "Extension.url"
      },
      "path": "Extension.extension.extension.url",
      "fixedUri": "type"
    }, {
      "path": "Extension.extension.extension.value[x]",
      "min": 0,
      "definition": "The type of attribute estimate, eg confidence interval or p value.",
      "short": "The type of attribute estimate, eg confidence interval or p value",
      "type": [ {
        "code": "CodeableConcept"
      } ],
      "binding": {
        "strength": "extensible",
        "valueSet": "http://hl7.org/fhir/uv/xver/ValueSet/R4B-attribute-estimate-type-for-R4|0.1.0"
      },
      "max": "1",
      "id": "Extension.extension:attributeEstimate.extension:type.value[x]",
      "base": {
        "max": "1",
        "min": 0,
        "path": "Extension.value[x]"
      }
    }, {
      "path": "Extension.extension.extension",
      "requirements": "Element `Evidence.statistic.attributeEstimate.quantity` is part of an existing definition because parent element `Evidence.statistic.attributeEstimate` requires a cross-version extension.\nElement `Evidence.statistic.attributeEstimate.quantity` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.attributeEstimate.quantity` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
      "min": 0,
      "definition": "R4B: `Evidence.statistic.attributeEstimate.quantity` (new:Quantity)",
      "short": "R4B: The singular quantity of the attribute estimate, for attribute estimates represented as single values; also used to report unit of measure (new)",
      "sliceName": "quantity",
      "max": "1",
      "id": "Extension.extension:attributeEstimate.extension:quantity",
      "comment": "Element `Evidence.statistic.attributeEstimate.quantity` is part of an existing definition because parent element `Evidence.statistic.attributeEstimate` requires a cross-version extension.\nElement `Evidence.statistic.attributeEstimate.quantity` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.attributeEstimate.quantity` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).\nOften the p value",
      "base": {
        "max": "*",
        "min": 0,
        "path": "Extension.extension"
      }
    }, {
      "id": "Extension.extension:attributeEstimate.extension:quantity.url",
      "max": "1",
      "min": 1,
      "base": {
        "max": "1",
        "min": 1,
        "path": "Extension.url"
      },
      "path": "Extension.extension.extension.url",
      "fixedUri": "quantity"
    }, {
      "path": "Extension.extension.extension.value[x]",
      "min": 0,
      "definition": "The singular quantity of the attribute estimate, for attribute estimates represented as single values; also used to report unit of measure.",
      "short": "The singular quantity of the attribute estimate, for attribute estimates represented as single values; also used to report unit of measure",
      "type": [ {
        "code": "Quantity"
      } ],
      "max": "1",
      "id": "Extension.extension:attributeEstimate.extension:quantity.value[x]",
      "comment": "Often the p value",
      "base": {
        "max": "1",
        "min": 0,
        "path": "Extension.value[x]"
      }
    }, {
      "path": "Extension.extension.extension",
      "requirements": "Element `Evidence.statistic.attributeEstimate.level` is part of an existing definition because parent element `Evidence.statistic.attributeEstimate` requires a cross-version extension.\nElement `Evidence.statistic.attributeEstimate.level` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.attributeEstimate.level` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
      "min": 0,
      "definition": "R4B: `Evidence.statistic.attributeEstimate.level` (new:decimal)",
      "short": "R4B: Level of confidence interval, eg 0.95 for 95% confidence interval (new)",
      "sliceName": "level",
      "max": "1",
      "id": "Extension.extension:attributeEstimate.extension:level",
      "comment": "Element `Evidence.statistic.attributeEstimate.level` is part of an existing definition because parent element `Evidence.statistic.attributeEstimate` requires a cross-version extension.\nElement `Evidence.statistic.attributeEstimate.level` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.attributeEstimate.level` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
      "base": {
        "max": "*",
        "min": 0,
        "path": "Extension.extension"
      }
    }, {
      "id": "Extension.extension:attributeEstimate.extension:level.url",
      "max": "1",
      "min": 1,
      "base": {
        "max": "1",
        "min": 1,
        "path": "Extension.url"
      },
      "path": "Extension.extension.extension.url",
      "fixedUri": "level"
    }, {
      "id": "Extension.extension:attributeEstimate.extension:level.value[x]",
      "max": "1",
      "min": 0,
      "base": {
        "max": "1",
        "min": 0,
        "path": "Extension.value[x]"
      },
      "path": "Extension.extension.extension.value[x]",
      "type": [ {
        "code": "decimal"
      } ],
      "short": "Level of confidence interval, eg 0.95 for 95% confidence interval",
      "definition": "Use 95 for a 95% confidence interval."
    }, {
      "path": "Extension.extension.extension",
      "requirements": "Element `Evidence.statistic.attributeEstimate.range` is part of an existing definition because parent element `Evidence.statistic.attributeEstimate` requires a cross-version extension.\nElement `Evidence.statistic.attributeEstimate.range` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.attributeEstimate.range` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
      "min": 0,
      "definition": "R4B: `Evidence.statistic.attributeEstimate.range` (new:Range)",
      "short": "R4B: Lower and upper bound values of the attribute estimate (new)",
      "sliceName": "range",
      "max": "1",
      "id": "Extension.extension:attributeEstimate.extension:range",
      "comment": "Element `Evidence.statistic.attributeEstimate.range` is part of an existing definition because parent element `Evidence.statistic.attributeEstimate` requires a cross-version extension.\nElement `Evidence.statistic.attributeEstimate.range` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.attributeEstimate.range` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
      "base": {
        "max": "*",
        "min": 0,
        "path": "Extension.extension"
      }
    }, {
      "id": "Extension.extension:attributeEstimate.extension:range.url",
      "max": "1",
      "min": 1,
      "base": {
        "max": "1",
        "min": 1,
        "path": "Extension.url"
      },
      "path": "Extension.extension.extension.url",
      "fixedUri": "range"
    }, {
      "id": "Extension.extension:attributeEstimate.extension:range.value[x]",
      "max": "1",
      "min": 0,
      "base": {
        "max": "1",
        "min": 0,
        "path": "Extension.value[x]"
      },
      "path": "Extension.extension.extension.value[x]",
      "type": [ {
        "code": "Range"
      } ],
      "short": "Lower and upper bound values of the attribute estimate",
      "definition": "Lower bound of confidence interval."
    }, {
      "path": "Extension.extension.extension",
      "requirements": "Element `Evidence.statistic.attributeEstimate.attributeEstimate` is part of an existing definition because parent element `Evidence.statistic.attributeEstimate` requires a cross-version extension.\nElement `Evidence.statistic.attributeEstimate.attributeEstimate` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.attributeEstimate.attributeEstimate` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
      "min": 0,
      "definition": "R4B: `Evidence.statistic.attributeEstimate.attributeEstimate` (new:Evidence.statistic.attributeEstimate)",
      "short": "R4B: A nested attribute estimate; which is the attribute estimate of an attribute estimate (new)",
      "sliceName": "attributeEstimate",
      "max": "*",
      "id": "Extension.extension:attributeEstimate.extension:attributeEstimate",
      "comment": "Element `Evidence.statistic.attributeEstimate.attributeEstimate` is part of an existing definition because parent element `Evidence.statistic.attributeEstimate` requires a cross-version extension.\nElement `Evidence.statistic.attributeEstimate.attributeEstimate` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.attributeEstimate.attributeEstimate` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).\nA nested attribute estimate; which is the attribute estimate of an attribute estimate",
      "base": {
        "max": "*",
        "min": 0,
        "path": "Extension.extension"
      }
    }, {
      "id": "Extension.extension:attributeEstimate.extension:attributeEstimate.url",
      "max": "1",
      "min": 1,
      "base": {
        "max": "1",
        "min": 1,
        "path": "Extension.url"
      },
      "path": "Extension.extension.extension.url",
      "fixedUri": "http://hl7.org/fhir/4.3/StructureDefinition/extension-Evidence.statistic.attributeEstimate"
    }, {
      "id": "Extension.extension:attributeEstimate.extension:attributeEstimate.value[x]",
      "max": "0",
      "min": 0,
      "base": {
        "max": "1",
        "min": 0,
        "path": "Extension.value[x]"
      },
      "path": "Extension.extension.extension.value[x]"
    }, {
      "id": "Extension.extension:attributeEstimate.url",
      "max": "1",
      "min": 1,
      "base": {
        "max": "1",
        "min": 1,
        "path": "Extension.url"
      },
      "path": "Extension.extension.url",
      "fixedUri": "attributeEstimate"
    }, {
      "id": "Extension.extension:attributeEstimate.value[x]",
      "max": "0",
      "min": 0,
      "base": {
        "max": "1",
        "min": 0,
        "path": "Extension.value[x]"
      },
      "path": "Extension.extension.value[x]"
    }, {
      "path": "Extension.extension",
      "requirements": "Element `Evidence.statistic.modelCharacteristic` is part of an existing definition because parent element `Evidence.statistic` requires a cross-version extension.\nElement `Evidence.statistic.modelCharacteristic` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.modelCharacteristic` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
      "min": 0,
      "definition": "R4B: `Evidence.statistic.modelCharacteristic` (new:BackboneElement)",
      "short": "R4B: An aspect of the statistical model (new)",
      "sliceName": "modelCharacteristic",
      "max": "*",
      "id": "Extension.extension:modelCharacteristic",
      "comment": "Element `Evidence.statistic.modelCharacteristic` is part of an existing definition because parent element `Evidence.statistic` requires a cross-version extension.\nElement `Evidence.statistic.modelCharacteristic` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.modelCharacteristic` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
      "base": {
        "max": "*",
        "min": 0,
        "path": "Extension.extension"
      }
    }, {
      "id": "Extension.extension:modelCharacteristic.extension",
      "max": "*",
      "min": 1,
      "base": {
        "max": "*",
        "min": 0,
        "path": "Extension.extension"
      },
      "path": "Extension.extension.extension",
      "slicing": {
        "rules": "open",
        "ordered": false,
        "discriminator": [ {
          "path": "url",
          "type": "value"
        } ]
      }
    }, {
      "path": "Extension.extension.extension",
      "requirements": "Element `Evidence.statistic.modelCharacteristic.code` is part of an existing definition because parent element `Evidence.statistic.modelCharacteristic` requires a cross-version extension.\nElement `Evidence.statistic.modelCharacteristic.code` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.modelCharacteristic.code` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
      "min": 1,
      "definition": "R4B: `Evidence.statistic.modelCharacteristic.code` (new:CodeableConcept)",
      "short": "R4B: Model specification (new)",
      "sliceName": "code",
      "max": "1",
      "id": "Extension.extension:modelCharacteristic.extension:code",
      "comment": "Element `Evidence.statistic.modelCharacteristic.code` is part of an existing definition because parent element `Evidence.statistic.modelCharacteristic` requires a cross-version extension.\nElement `Evidence.statistic.modelCharacteristic.code` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.modelCharacteristic.code` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
      "base": {
        "max": "*",
        "min": 0,
        "path": "Extension.extension"
      }
    }, {
      "id": "Extension.extension:modelCharacteristic.extension:code.url",
      "max": "1",
      "min": 1,
      "base": {
        "max": "1",
        "min": 1,
        "path": "Extension.url"
      },
      "path": "Extension.extension.extension.url",
      "fixedUri": "code"
    }, {
      "path": "Extension.extension.extension.value[x]",
      "min": 1,
      "definition": "Description of a component of the method to generate the statistic.",
      "short": "Model specification",
      "type": [ {
        "code": "CodeableConcept"
      } ],
      "binding": {
        "strength": "extensible",
        "valueSet": "http://hl7.org/fhir/uv/xver/ValueSet/R4B-statistic-model-code-for-R4|0.1.0"
      },
      "max": "1",
      "id": "Extension.extension:modelCharacteristic.extension:code.value[x]",
      "base": {
        "max": "1",
        "min": 0,
        "path": "Extension.value[x]"
      }
    }, {
      "path": "Extension.extension.extension",
      "requirements": "Element `Evidence.statistic.modelCharacteristic.value` is part of an existing definition because parent element `Evidence.statistic.modelCharacteristic` requires a cross-version extension.\nElement `Evidence.statistic.modelCharacteristic.value` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.modelCharacteristic.value` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
      "min": 0,
      "definition": "R4B: `Evidence.statistic.modelCharacteristic.value` (new:Quantity[SimpleQuantity])",
      "short": "R4B: Numerical value to complete model specification (new)",
      "sliceName": "value",
      "max": "1",
      "id": "Extension.extension:modelCharacteristic.extension:value",
      "comment": "Element `Evidence.statistic.modelCharacteristic.value` is part of an existing definition because parent element `Evidence.statistic.modelCharacteristic` requires a cross-version extension.\nElement `Evidence.statistic.modelCharacteristic.value` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.modelCharacteristic.value` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
      "base": {
        "max": "*",
        "min": 0,
        "path": "Extension.extension"
      }
    }, {
      "id": "Extension.extension:modelCharacteristic.extension:value.url",
      "max": "1",
      "min": 1,
      "base": {
        "max": "1",
        "min": 1,
        "path": "Extension.url"
      },
      "path": "Extension.extension.extension.url",
      "fixedUri": "value"
    }, {
      "id": "Extension.extension:modelCharacteristic.extension:value.value[x]",
      "max": "1",
      "min": 0,
      "base": {
        "max": "1",
        "min": 0,
        "path": "Extension.value[x]"
      },
      "path": "Extension.extension.extension.value[x]",
      "type": [ {
        "code": "Quantity",
        "profile": [ "http://hl7.org/fhir/StructureDefinition/SimpleQuantity|4.0.1" ]
      } ],
      "short": "Numerical value to complete model specification",
      "definition": "Further specification of the quantified value of the component of the method to generate the statistic."
    }, {
      "path": "Extension.extension.extension",
      "requirements": "Element `Evidence.statistic.modelCharacteristic.variable` is part of an existing definition because parent element `Evidence.statistic.modelCharacteristic` requires a cross-version extension.\nElement `Evidence.statistic.modelCharacteristic.variable` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.modelCharacteristic.variable` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
      "min": 0,
      "definition": "R4B: `Evidence.statistic.modelCharacteristic.variable` (new:BackboneElement)",
      "short": "R4B: A variable adjusted for in the adjusted analysis (new)",
      "sliceName": "variable",
      "max": "*",
      "id": "Extension.extension:modelCharacteristic.extension:variable",
      "comment": "Element `Evidence.statistic.modelCharacteristic.variable` is part of an existing definition because parent element `Evidence.statistic.modelCharacteristic` requires a cross-version extension.\nElement `Evidence.statistic.modelCharacteristic.variable` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.modelCharacteristic.variable` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
      "base": {
        "max": "*",
        "min": 0,
        "path": "Extension.extension"
      }
    }, {
      "id": "Extension.extension:modelCharacteristic.extension:variable.extension",
      "max": "*",
      "min": 1,
      "base": {
        "max": "*",
        "min": 0,
        "path": "Extension.extension"
      },
      "path": "Extension.extension.extension.extension",
      "slicing": {
        "rules": "open",
        "ordered": false,
        "discriminator": [ {
          "path": "url",
          "type": "value"
        } ]
      }
    }, {
      "path": "Extension.extension.extension.extension",
      "requirements": "Element `Evidence.statistic.modelCharacteristic.variable.variableDefinition` is part of an existing definition because parent element `Evidence.statistic.modelCharacteristic.variable` requires a cross-version extension.\nElement `Evidence.statistic.modelCharacteristic.variable.variableDefinition` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.modelCharacteristic.variable.variableDefinition` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
      "min": 1,
      "definition": "R4B: `Evidence.statistic.modelCharacteristic.variable.variableDefinition` (new:Reference(Group,EvidenceVariable))",
      "short": "R4B: Description of the variable (new)",
      "sliceName": "variableDefinition",
      "max": "1",
      "id": "Extension.extension:modelCharacteristic.extension:variable.extension:variableDefinition",
      "comment": "Element `Evidence.statistic.modelCharacteristic.variable.variableDefinition` is part of an existing definition because parent element `Evidence.statistic.modelCharacteristic.variable` requires a cross-version extension.\nElement `Evidence.statistic.modelCharacteristic.variable.variableDefinition` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.modelCharacteristic.variable.variableDefinition` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
      "base": {
        "max": "*",
        "min": 0,
        "path": "Extension.extension"
      }
    }, {
      "id": "Extension.extension:modelCharacteristic.extension:variable.extension:variableDefinition.url",
      "max": "1",
      "min": 1,
      "base": {
        "max": "1",
        "min": 1,
        "path": "Extension.url"
      },
      "path": "Extension.extension.extension.extension.url",
      "fixedUri": "variableDefinition"
    }, {
      "id": "Extension.extension:modelCharacteristic.extension:variable.extension:variableDefinition.value[x]",
      "max": "1",
      "min": 1,
      "base": {
        "max": "1",
        "min": 0,
        "path": "Extension.value[x]"
      },
      "path": "Extension.extension.extension.extension.value[x]",
      "type": [ {
        "code": "Reference",
        "targetProfile": [ "http://hl7.org/fhir/4.3/StructureDefinition/profile-Group|0.1.0", "http://hl7.org/fhir/StructureDefinition/Group|4.0.1", "http://hl7.org/fhir/4.3/StructureDefinition/profile-EvidenceVariable|0.1.0", "http://hl7.org/fhir/StructureDefinition/EvidenceVariable|4.0.1" ]
      } ],
      "short": "Description of the variable",
      "definition": "Description of the variable."
    }, {
      "path": "Extension.extension.extension.extension",
      "requirements": "Element `Evidence.statistic.modelCharacteristic.variable.handling` is part of an existing definition because parent element `Evidence.statistic.modelCharacteristic.variable` requires a cross-version extension.\nElement `Evidence.statistic.modelCharacteristic.variable.handling` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.modelCharacteristic.variable.handling` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
      "min": 0,
      "definition": "R4B: `Evidence.statistic.modelCharacteristic.variable.handling` (new:code)",
      "short": "R4B: continuous | dichotomous | ordinal | polychotomous (new)",
      "sliceName": "handling",
      "max": "1",
      "id": "Extension.extension:modelCharacteristic.extension:variable.extension:handling",
      "comment": "Element `Evidence.statistic.modelCharacteristic.variable.handling` is part of an existing definition because parent element `Evidence.statistic.modelCharacteristic.variable` requires a cross-version extension.\nElement `Evidence.statistic.modelCharacteristic.variable.handling` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.modelCharacteristic.variable.handling` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
      "base": {
        "max": "*",
        "min": 0,
        "path": "Extension.extension"
      }
    }, {
      "id": "Extension.extension:modelCharacteristic.extension:variable.extension:handling.url",
      "max": "1",
      "min": 1,
      "base": {
        "max": "1",
        "min": 1,
        "path": "Extension.url"
      },
      "path": "Extension.extension.extension.extension.url",
      "fixedUri": "handling"
    }, {
      "path": "Extension.extension.extension.extension.value[x]",
      "min": 0,
      "definition": "How the variable is classified for use in adjusted analysis.",
      "short": "continuous | dichotomous | ordinal | polychotomous",
      "type": [ {
        "code": "code"
      } ],
      "binding": {
        "strength": "required",
        "valueSet": "http://hl7.org/fhir/uv/xver/ValueSet/R4B-variable-handling-for-R4|0.1.0"
      },
      "max": "1",
      "id": "Extension.extension:modelCharacteristic.extension:variable.extension:handling.value[x]",
      "base": {
        "max": "1",
        "min": 0,
        "path": "Extension.value[x]"
      }
    }, {
      "path": "Extension.extension.extension.extension",
      "requirements": "Element `Evidence.statistic.modelCharacteristic.variable.valueCategory` is part of an existing definition because parent element `Evidence.statistic.modelCharacteristic.variable` requires a cross-version extension.\nElement `Evidence.statistic.modelCharacteristic.variable.valueCategory` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.modelCharacteristic.variable.valueCategory` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
      "min": 0,
      "definition": "R4B: `Evidence.statistic.modelCharacteristic.variable.valueCategory` (new:CodeableConcept)",
      "short": "R4B: Description for grouping of ordinal or polychotomous variables (new)",
      "sliceName": "valueCategory",
      "max": "*",
      "id": "Extension.extension:modelCharacteristic.extension:variable.extension:valueCategory",
      "comment": "Element `Evidence.statistic.modelCharacteristic.variable.valueCategory` is part of an existing definition because parent element `Evidence.statistic.modelCharacteristic.variable` requires a cross-version extension.\nElement `Evidence.statistic.modelCharacteristic.variable.valueCategory` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.modelCharacteristic.variable.valueCategory` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
      "base": {
        "max": "*",
        "min": 0,
        "path": "Extension.extension"
      }
    }, {
      "id": "Extension.extension:modelCharacteristic.extension:variable.extension:valueCategory.url",
      "max": "1",
      "min": 1,
      "base": {
        "max": "1",
        "min": 1,
        "path": "Extension.url"
      },
      "path": "Extension.extension.extension.extension.url",
      "fixedUri": "valueCategory"
    }, {
      "id": "Extension.extension:modelCharacteristic.extension:variable.extension:valueCategory.value[x]",
      "max": "1",
      "min": 0,
      "base": {
        "max": "1",
        "min": 0,
        "path": "Extension.value[x]"
      },
      "path": "Extension.extension.extension.extension.value[x]",
      "type": [ {
        "code": "CodeableConcept"
      } ],
      "short": "Description for grouping of ordinal or polychotomous variables",
      "definition": "Description for grouping of ordinal or polychotomous variables."
    }, {
      "path": "Extension.extension.extension.extension",
      "requirements": "Element `Evidence.statistic.modelCharacteristic.variable.valueQuantity` is part of an existing definition because parent element `Evidence.statistic.modelCharacteristic.variable` requires a cross-version extension.\nElement `Evidence.statistic.modelCharacteristic.variable.valueQuantity` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.modelCharacteristic.variable.valueQuantity` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
      "min": 0,
      "definition": "R4B: `Evidence.statistic.modelCharacteristic.variable.valueQuantity` (new:Quantity)",
      "short": "R4B: Discrete value for grouping of ordinal or polychotomous variables (new)",
      "sliceName": "valueQuantity",
      "max": "*",
      "id": "Extension.extension:modelCharacteristic.extension:variable.extension:valueQuantity",
      "comment": "Element `Evidence.statistic.modelCharacteristic.variable.valueQuantity` is part of an existing definition because parent element `Evidence.statistic.modelCharacteristic.variable` requires a cross-version extension.\nElement `Evidence.statistic.modelCharacteristic.variable.valueQuantity` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.modelCharacteristic.variable.valueQuantity` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
      "base": {
        "max": "*",
        "min": 0,
        "path": "Extension.extension"
      }
    }, {
      "id": "Extension.extension:modelCharacteristic.extension:variable.extension:valueQuantity.url",
      "max": "1",
      "min": 1,
      "base": {
        "max": "1",
        "min": 1,
        "path": "Extension.url"
      },
      "path": "Extension.extension.extension.extension.url",
      "fixedUri": "valueQuantity"
    }, {
      "id": "Extension.extension:modelCharacteristic.extension:variable.extension:valueQuantity.value[x]",
      "max": "1",
      "min": 0,
      "base": {
        "max": "1",
        "min": 0,
        "path": "Extension.value[x]"
      },
      "path": "Extension.extension.extension.extension.value[x]",
      "type": [ {
        "code": "Quantity"
      } ],
      "short": "Discrete value for grouping of ordinal or polychotomous variables",
      "definition": "Discrete value for grouping of ordinal or polychotomous variables."
    }, {
      "path": "Extension.extension.extension.extension",
      "requirements": "Element `Evidence.statistic.modelCharacteristic.variable.valueRange` is part of an existing definition because parent element `Evidence.statistic.modelCharacteristic.variable` requires a cross-version extension.\nElement `Evidence.statistic.modelCharacteristic.variable.valueRange` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.modelCharacteristic.variable.valueRange` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
      "min": 0,
      "definition": "R4B: `Evidence.statistic.modelCharacteristic.variable.valueRange` (new:Range)",
      "short": "R4B: Range of values for grouping of ordinal or polychotomous variables (new)",
      "sliceName": "valueRange",
      "max": "*",
      "id": "Extension.extension:modelCharacteristic.extension:variable.extension:valueRange",
      "comment": "Element `Evidence.statistic.modelCharacteristic.variable.valueRange` is part of an existing definition because parent element `Evidence.statistic.modelCharacteristic.variable` requires a cross-version extension.\nElement `Evidence.statistic.modelCharacteristic.variable.valueRange` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.modelCharacteristic.variable.valueRange` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
      "base": {
        "max": "*",
        "min": 0,
        "path": "Extension.extension"
      }
    }, {
      "id": "Extension.extension:modelCharacteristic.extension:variable.extension:valueRange.url",
      "max": "1",
      "min": 1,
      "base": {
        "max": "1",
        "min": 1,
        "path": "Extension.url"
      },
      "path": "Extension.extension.extension.extension.url",
      "fixedUri": "valueRange"
    }, {
      "id": "Extension.extension:modelCharacteristic.extension:variable.extension:valueRange.value[x]",
      "max": "1",
      "min": 0,
      "base": {
        "max": "1",
        "min": 0,
        "path": "Extension.value[x]"
      },
      "path": "Extension.extension.extension.extension.value[x]",
      "type": [ {
        "code": "Range"
      } ],
      "short": "Range of values for grouping of ordinal or polychotomous variables",
      "definition": "Range of values for grouping of ordinal or polychotomous variables."
    }, {
      "id": "Extension.extension:modelCharacteristic.extension:variable.url",
      "max": "1",
      "min": 1,
      "base": {
        "max": "1",
        "min": 1,
        "path": "Extension.url"
      },
      "path": "Extension.extension.extension.url",
      "fixedUri": "variable"
    }, {
      "id": "Extension.extension:modelCharacteristic.extension:variable.value[x]",
      "max": "0",
      "min": 0,
      "base": {
        "max": "1",
        "min": 0,
        "path": "Extension.value[x]"
      },
      "path": "Extension.extension.extension.value[x]"
    }, {
      "path": "Extension.extension.extension",
      "requirements": "Element `Evidence.statistic.modelCharacteristic.attributeEstimate` is part of an existing definition because parent element `Evidence.statistic.modelCharacteristic` requires a cross-version extension.\nElement `Evidence.statistic.modelCharacteristic.attributeEstimate` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.modelCharacteristic.attributeEstimate` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
      "min": 0,
      "definition": "R4B: `Evidence.statistic.modelCharacteristic.attributeEstimate` (new:Evidence.statistic.attributeEstimate)",
      "short": "R4B: An attribute of the statistic used as a model characteristic (new)",
      "sliceName": "attributeEstimate",
      "max": "*",
      "id": "Extension.extension:modelCharacteristic.extension:attributeEstimate",
      "comment": "Element `Evidence.statistic.modelCharacteristic.attributeEstimate` is part of an existing definition because parent element `Evidence.statistic.modelCharacteristic` requires a cross-version extension.\nElement `Evidence.statistic.modelCharacteristic.attributeEstimate` has a context of Evidence based on following the parent source element upwards and mapping to `Evidence`.\nElement `Evidence.statistic.modelCharacteristic.attributeEstimate` has no mapping targets in FHIR R4. Typically, this is because the element has been added (is a new element).",
      "base": {
        "max": "*",
        "min": 0,
        "path": "Extension.extension"
      }
    }, {
      "id": "Extension.extension:modelCharacteristic.extension:attributeEstimate.url",
      "max": "1",
      "min": 1,
      "base": {
        "max": "1",
        "min": 1,
        "path": "Extension.url"
      },
      "path": "Extension.extension.extension.url",
      "fixedUri": "http://hl7.org/fhir/4.3/StructureDefinition/extension-Evidence.statistic.attributeEstimate"
    }, {
      "id": "Extension.extension:modelCharacteristic.extension:attributeEstimate.value[x]",
      "max": "0",
      "min": 0,
      "base": {
        "max": "1",
        "min": 0,
        "path": "Extension.value[x]"
      },
      "path": "Extension.extension.extension.value[x]"
    }, {
      "id": "Extension.extension:modelCharacteristic.url",
      "max": "1",
      "min": 1,
      "base": {
        "max": "1",
        "min": 1,
        "path": "Extension.url"
      },
      "path": "Extension.extension.url",
      "fixedUri": "modelCharacteristic"
    }, {
      "id": "Extension.extension:modelCharacteristic.value[x]",
      "max": "0",
      "min": 0,
      "base": {
        "max": "1",
        "min": 0,
        "path": "Extension.value[x]"
      },
      "path": "Extension.extension.value[x]"
    }, {
      "id": "Extension.url",
      "max": "1",
      "min": 1,
      "base": {
        "max": "1",
        "min": 1,
        "path": "Extension.url"
      },
      "path": "Extension.url",
      "fixedUri": "http://hl7.org/fhir/4.3/StructureDefinition/extension-Evidence.statistic"
    }, {
      "id": "Extension.value[x]",
      "max": "0",
      "min": 0,
      "base": {
        "max": "1",
        "min": 0,
        "path": "Extension.value[x]"
      },
      "path": "Extension.value[x]"
    } ]
  },
  "contact": [ {
    "name": "FHIR Infrastructure",
    "telecom": [ {
      "value": "http://www.hl7.org/Special/committees/fiwg",
      "system": "url"
    } ]
  } ],
  "baseDefinition": "http://hl7.org/fhir/StructureDefinition/Extension|4.0.1"
}