{
"description": "This value set includes concept codes for specific substances/pharmaceutical products, allergy or intolerance conditions, and negation/exclusion codes to specify the absence of specific types of allergies or intolerances.",
"compose": {
"include": [ {
"valueSet": [ "http://hl7.org/fhir/ValueSet/substance-code" ]
}, {
"filter": [ {
"op": "is-a",
"value": "418038007",
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} ],
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}, {
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"op": "is-a",
"value": "267425008",
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} ],
"system": "http://snomed.info/sct"
}, {
"filter": [ {
"op": "is-a",
"value": "29736007",
"property": "concept"
} ],
"system": "http://snomed.info/sct"
}, {
"filter": [ {
"op": "is-a",
"value": "340519003",
"property": "concept"
} ],
"system": "http://snomed.info/sct"
}, {
"filter": [ {
"op": "is-a",
"value": "190753003",
"property": "concept"
} ],
"system": "http://snomed.info/sct"
}, {
"filter": [ {
"op": "is-a",
"value": "413427002",
"property": "concept"
} ],
"system": "http://snomed.info/sct"
}, {
"filter": [ {
"op": "is-a",
"value": "716186003",
"property": "concept"
} ],
"system": "http://snomed.info/sct"
} ]
},
"_filename": "ValueSet-allergyintolerance-code.json",
"package_name": "hl7.fhir.r6.expansions",
"date": null,
"meta": {
"profile": [ "http://hl7.org/fhir/StructureDefinition/shareablevalueset" ],
"lastUpdated": "2025-04-01T12:16:37.966+11:00"
},
"publisher": "FHIR Project team",
"jurisdiction": [ {
"coding": [ {
"code": "001",
"system": "http://unstats.un.org/unsd/methods/m49/m49.htm",
"display": "World"
} ]
} ],
"name": "SubstanceProductAndConditionAndNegationCodes",
"copyright": "This resource includes content from SNOMED Clinical Terms® (SNOMED CT®) which is copyright of the International Health Terminology Standards Development Organisation (IHTSDO). Implementers of these specifications must have the appropriate SNOMED CT Affiliate license - for more information contact http://www.snomed.org/snomed-ct/get-snomed-ct or info@snomed.org",
"type": null,
"experimental": "false",
"resourceType": "ValueSet",
"expansion": {
"offset": 0,
"contains": [ {
"code": "105590001",
"system": "http://snomed.info/sct",
"display": "Substance",
"designation": [ {
"use": {
"code": "display",
"system": "http://terminology.hl7.org/CodeSystem/designation-usage"
},
"value": "Substances",
"language": "en"
}, {
"use": {
"code": "display",
"system": "http://terminology.hl7.org/CodeSystem/designation-usage"
},
"value": "Substance (substance)",
"language": "en"
} ]
}, {
"code": "102002",
"system": "http://snomed.info/sct",
"display": "Hemoglobin Okaloosa",
"designation": [ {
"use": {
"code": "display",
"system": "http://terminology.hl7.org/CodeSystem/designation-usage"
},
"value": "Hb 48(CD7), Leu-arg",
"language": "en"
}, {
"use": {
"code": "display",
"system": "http://terminology.hl7.org/CodeSystem/designation-usage"
},
"value": "Haemoglobin Okaloosa",
"language": "en"
}, {
"use": {
"code": "display",
"system": "http://terminology.hl7.org/CodeSystem/designation-usage"
},
"value": "Hemoglobin Okaloosa (substance)",
"language": "en"
} ]
}, {
"code": "120006",
"system": "http://snomed.info/sct",
"display": "Ornithine racemase",
"designation": [ {
"use": {
"code": "display",
"system": "http://terminology.hl7.org/CodeSystem/designation-usage"
},
"value": "Ornithine racemase (substance)",
"language": "en"
} ]
}, {
"code": "125001",
"system": "http://snomed.info/sct",
"display": "Ferrous (59-Fe) sulfate (substance)",
"designation": [ {
"use": {
"code": "display",
"system": "http://terminology.hl7.org/CodeSystem/designation-usage"
},
"value": "Ferrous (59-Fe) sulfate",
"language": "en"
} ]
}, {
"code": "126000",
"system": "http://snomed.info/sct",
"display": "Galactosyl-N-acetylglucosaminylgalactosylglucosylceramide alpha-galactosyltransferase",
"designation": [ {
"use": {
"code": "display",
"system": "http://terminology.hl7.org/CodeSystem/designation-usage"
},
"value": "Galactosyl-N-acetylglucosaminylgalactosylglucosylceramide alpha-galactosyltransferase (substance)",
"language": "en"
} ]
}, {
"code": "130002",
"system": "http://snomed.info/sct",
"display": "Hemoglobin Hopkins-II",
"designation": [ {
"use": {
"code": "display",
"system": "http://terminology.hl7.org/CodeSystem/designation-usage"
},
"value": "Hb 112(G19), His-asp",
"language": "en"
}, {
"use": {
"code": "display",
"system": "http://terminology.hl7.org/CodeSystem/designation-usage"
},
"value": "Haemoglobin Hopkins-II",
"language": "en"
}, {
"use": {
"code": "display",
"system": "http://terminology.hl7.org/CodeSystem/designation-usage"
},
"value": "Hemoglobin Hopkins-II (substance)",
"language": "en"
} ]
}, {
"code": "131003",
"system": "http://snomed.info/sct",
"display": "Dolichyl-phosphate mannosyltransferase",
"designation": [ {
"use": {
"code": "display",
"system": "http://terminology.hl7.org/CodeSystem/designation-usage"
},
"value": "Dolichyl-phosphate mannosyltransferase (substance)",
"language": "en"
} ]
}, {
"code": "159002",
"system": "http://snomed.info/sct",
"display": "Ferrocyanide salt",
"designation": [ {
"use": {
"code": "display",
"system": "http://terminology.hl7.org/CodeSystem/designation-usage"
},
"value": "Ferrocyanide salt (substance)",
"language": "en"
} ]
}, {
"code": "164003",
"system": "http://snomed.info/sct",
"display": "Phosphoenolpyruvate-protein phosphotransferase",
"designation": [ {
"use": {
"code": "display",
"system": "http://terminology.hl7.org/CodeSystem/designation-usage"
},
"value": "Enzyme I of the phosphotransferase system",
"language": "en"
}, {
"use": {
"code": "display",
"system": "http://terminology.hl7.org/CodeSystem/designation-usage"
},
"value": "Phosphoenolpyruvate-protein phosphotransferase (substance)",
"language": "en"
} ]
}, {
"code": "178002",
"system": "http://snomed.info/sct",
"display": "Uridine diphosphate galactose",
"designation": [ {
"use": {
"code": "display",
"system": "http://terminology.hl7.org/CodeSystem/designation-usage"
},
"value": "Uridine diphosphate galactose (substance)",
"language": "en"
}, {
"use": {
"code": "display",
"system": "http://terminology.hl7.org/CodeSystem/designation-usage"
},
"value": "Uridyl diphosphate galactose",
"language": "en"
}, {
"use": {
"code": "display",
"system": "http://terminology.hl7.org/CodeSystem/designation-usage"
},
"value": "UDP - Uridyl diphosphate galactose",
"language": "en"
} ]
}, {
"code": "186002",
"system": "http://snomed.info/sct",
"display": "HLA-Cw9 antigen",
"designation": [ {
"use": {
"code": "display",
"system": "http://terminology.hl7.org/CodeSystem/designation-usage"
},
"value": "Human leukocyte antigen Cw9",
"language": "en"
}, {
"use": {
"code": "display",
"system": "http://terminology.hl7.org/CodeSystem/designation-usage"
},
"value": "Human leucocyte antigen Cw9",
"language": "en"
}, {
"use": {
"code": "display",
"system": "http://terminology.hl7.org/CodeSystem/designation-usage"
},
"value": "Human leukocyte antigen Cw9 (substance)",
"language": "en"
} ]
}, {
"code": "187006",
"system": "http://snomed.info/sct",
"display": "Cyanocobalamin (57-Co) (substance)",
"designation": [ {
"use": {
"code": "display",
"system": "http://terminology.hl7.org/CodeSystem/designation-usage"
},
"value": "Cyanocobalamin (57-Co)",
"language": "en"
} ]
}, {
"code": "200001",
"system": "http://snomed.info/sct",
"display": "Berberine",
"designation": [ {
"use": {
"code": "display",
"system": "http://terminology.hl7.org/CodeSystem/designation-usage"
},
"value": "Berberine (substance)",
"language": "en"
} ]
}, {
"code": "217008",
"system": "http://snomed.info/sct",
"display": "Blood group antigen IH",
"designation": [ {
"use": {
"code": "display",
"system": "http://terminology.hl7.org/CodeSystem/designation-usage"
},
"value": "Blood group antigen HI",
"language": "en"
}, {
"use": {
"code": "display",
"system": "http://terminology.hl7.org/CodeSystem/designation-usage"
},
"value": "Blood group antigen IO",
"language": "en"
}, {
"use": {
"code": "display",
"system": "http://terminology.hl7.org/CodeSystem/designation-usage"
},
"value": "Blood group antigen IH (substance)",
"language": "en"
} ]
}, {
"code": "231008",
"system": "http://snomed.info/sct",
"display": "3-hydroxyisobutyrate dehydrogenase",
"designation": [ {
"use": {
"code": "display",
"system": "http://terminology.hl7.org/CodeSystem/designation-usage"
},
"value": "3-hydroxyisobutyrate dehydrogenase (substance)",
"language": "en"
} ]
}, {
"code": "238002",
"system": "http://snomed.info/sct",
"display": "Heptachlor",
"designation": [ {
"use": {
"code": "display",
"system": "http://terminology.hl7.org/CodeSystem/designation-usage"
},
"value": "Heptachlor (substance)",
"language": "en"
} ]
}, {
"code": "261000",
"system": "http://snomed.info/sct",
"display": "Codeine phosphate",
"designation": [ {
"use": {
"code": "display",
"system": "http://terminology.hl7.org/CodeSystem/designation-usage"
},
"value": "Codeine phosphate (substance)",
"language": "en"
} ]
}, {
"code": "296000",
"system": "http://snomed.info/sct",
"display": "Coumachlor",
"designation": [ {
"use": {
"code": "display",
"system": "http://terminology.hl7.org/CodeSystem/designation-usage"
},
"value": "Coumachlor (substance)",
"language": "en"
} ]
}, {
"code": "327000",
"system": "http://snomed.info/sct",
"display": "Arsenic-76 (substance)",
"designation": [ {
"use": {
"code": "display",
"system": "http://terminology.hl7.org/CodeSystem/designation-usage"
},
"value": "Arsenic-76",
"language": "en"
}, {
"use": {
"code": "display",
"system": "http://terminology.hl7.org/CodeSystem/designation-usage"
},
"value": "76-As",
"language": "en"
} ]
}, {
"code": "329002",
"system": "http://snomed.info/sct",
"display": "Antimony-127 (substance)",
"designation": [ {
"use": {
"code": "display",
"system": "http://terminology.hl7.org/CodeSystem/designation-usage"
},
"value": "Antimony-127",
"language": "en"
}, {
"use": {
"code": "display",
"system": "http://terminology.hl7.org/CodeSystem/designation-usage"
},
"value": "127-Sb",
"language": "en"
} ]
}, {
"code": "336001",
"system": "http://snomed.info/sct",
"display": "Fibrinogen Tokyo II",
"designation": [ {
"use": {
"code": "display",
"system": "http://terminology.hl7.org/CodeSystem/designation-usage"
},
"value": "Fibrinogen Tokyo II (substance)",
"language": "en"
} ]
}, {
"code": "340005",
"system": "http://snomed.info/sct",
"display": "Enzyme variant",
"designation": [ {
"use": {
"code": "display",
"system": "http://terminology.hl7.org/CodeSystem/designation-usage"
},
"value": "Enzyme variant (substance)",
"language": "en"
} ]
}, {
"code": "363000",
"system": "http://snomed.info/sct",
"display": "Fibrinogen San Juan",
"designation": [ {
"use": {
"code": "display",
"system": "http://terminology.hl7.org/CodeSystem/designation-usage"
},
"value": "Fibrinogen San Juan (substance)",
"language": "en"
} ]
}, {
"code": "370000",
"system": "http://snomed.info/sct",
"display": "Beta>2S< glycoprotein (substance)",
"designation": [ {
"use": {
"code": "display",
"system": "http://terminology.hl7.org/CodeSystem/designation-usage"
},
"value": "Beta>2S< glycoprotein",
"language": "en"
} ]
}, {
"code": "371001",
"system": "http://snomed.info/sct",
"display": "Acylcarnitine hydrolase",
"designation": [ {
"use": {
"code": "display",
"system": "http://terminology.hl7.org/CodeSystem/designation-usage"
},
"value": "Acylcarnitine hydrolase (substance)",
"language": "en"
} ]
}, {
"code": "377002",
"system": "http://snomed.info/sct",
"display": "Sparteine",
"designation": [ {
"use": {
"code": "display",
"system": "http://terminology.hl7.org/CodeSystem/designation-usage"
},
"value": "Lupinidine",
"language": "en"
}, {
"use": {
"code": "display",
"system": "http://terminology.hl7.org/CodeSystem/designation-usage"
},
"value": "Sparteine (substance)",
"language": "en"
} ]
}, {
"code": "392001",
"system": "http://snomed.info/sct",
"display": "Gadolinium-151 (substance)",
"designation": [ {
"use": {
"code": "display",
"system": "http://terminology.hl7.org/CodeSystem/designation-usage"
},
"value": "151-Gd",
"language": "en"
}, {
"use": {
"code": "display",
"system": "http://terminology.hl7.org/CodeSystem/designation-usage"
},
"value": "Gadolinium-151",
"language": "en"
} ]
}, {
"code": "395004",
"system": "http://snomed.info/sct",
"display": "Immunoglobulin pentamer",
"designation": [ {
"use": {
"code": "display",
"system": "http://terminology.hl7.org/CodeSystem/designation-usage"
},
"value": "Immunoglobulin pentamer (substance)",
"language": "en"
} ]
}, {
"code": "412004",
"system": "http://snomed.info/sct",
"display": "Ribose-5-phosphate isomerase",
"designation": [ {
"use": {
"code": "display",
"system": "http://terminology.hl7.org/CodeSystem/designation-usage"
},
"value": "Phosphopentosisomerase",
"language": "en"
}, {
"use": {
"code": "display",
"system": "http://terminology.hl7.org/CodeSystem/designation-usage"
},
"value": "Phosphoriboisomerase",
"language": "en"
}, {
"use": {
"code": "display",
"system": "http://terminology.hl7.org/CodeSystem/designation-usage"
},
"value": "Ribose-5-phosphate isomerase (substance)",
"language": "en"
} ]
}, {
"code": "424006",
"system": "http://snomed.info/sct",
"display": "Citramalyl-CoA lyase",
"designation": [ {
"use": {
"code": "display",
"system": "http://terminology.hl7.org/CodeSystem/designation-usage"
},
"value": "Citramalyl-coenzyme A lyase",
"language": "en"
}, {
"use": {
"code": "display",
"system": "http://terminology.hl7.org/CodeSystem/designation-usage"
},
"value": "Citramalyl-coenzyme A lyase (substance)",
"language": "en"
} ]
}, {
"code": "425007",
"system": "http://snomed.info/sct",
"display": "Hemoglobin Nagoya",
"designation": [ {
"use": {
"code": "display",
"system": "http://terminology.hl7.org/CodeSystem/designation-usage"
},
"value": "Hb 97(FG4), His-pro",
"language": "en"
}, {
"use": {
"code": "display",
"system": "http://terminology.hl7.org/CodeSystem/designation-usage"
},
"value": "Haemoglobin Nagoya",
"language": "en"
}, {
"use": {
"code": "display",
"system": "http://terminology.hl7.org/CodeSystem/designation-usage"
},
"value": "Hemoglobin Nagoya (substance)",
"language": "en"
} ]
}, {
"code": "432003",
"system": "http://snomed.info/sct",
"display": "Carminic acid",
"designation": [ {
"use": {
"code": "display",
"system": "http://terminology.hl7.org/CodeSystem/designation-usage"
},
"value": "Carminic acid stain (substance)",
"language": "en"
}, {
"use": {
"code": "display",
"system": "http://terminology.hl7.org/CodeSystem/designation-usage"
},
"value": "Carminic acid stain",
"language": "en"
} ]
}, {
"code": "438004",
"system": "http://snomed.info/sct",
"display": "2-hydroxyglutarate dehydrogenase (substance)",
"designation": [ {
"use": {
"code": "display",
"system": "http://terminology.hl7.org/CodeSystem/designation-usage"
},
"value": "2-hydroxyglutarate dehydrogenase",
"language": "en"
} ]
}, {
"code": "462009",
"system": "http://snomed.info/sct",
"display": "Urease (ATP-hydrolysing)",
"designation": [ {
"use": {
"code": "display",
"system": "http://terminology.hl7.org/CodeSystem/designation-usage"
},
"value": "Urease (adenosine triphosphate-hydrolysing) (substance)",
"language": "en"
}, {
"use": {
"code": "display",
"system": "http://terminology.hl7.org/CodeSystem/designation-usage"
},
"value": "Urease (adenosine triphosphate-hydrolysing)",
"language": "en"
} ]
}, {
"code": "472007",
"system": "http://snomed.info/sct",
"display": "Vegetable textile fiber",
"designation": [ {
"use": {
"code": "display",
"system": "http://terminology.hl7.org/CodeSystem/designation-usage"
},
"value": "Vegetable textile fibre",
"language": "en"
}, {
"use": {
"code": "display",
"system": "http://terminology.hl7.org/CodeSystem/designation-usage"
},
"value": "Vegetable textile fiber (substance)",
"language": "en"
} ]
}, {
"code": "476005",
"system": "http://snomed.info/sct",
"display": "Lymphocyte antigen CD1b",
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"use": {
"code": "display",
"system": "http://terminology.hl7.org/CodeSystem/designation-usage"
},
"value": "Lymphocyte antigen CD1b (substance)",
"language": "en"
}, {
"use": {
"code": "display",
"system": "http://terminology.hl7.org/CodeSystem/designation-usage"
},
"value": "CD1b - Cluster of differentiation antigen 1b",
"language": "en"
}, {
"use": {
"code": "display",
"system": "http://terminology.hl7.org/CodeSystem/designation-usage"
},
"value": "Cluster of differentiation antigen 1b",
"language": "en"
} ]
}, {
"code": "498001",
"system": "http://snomed.info/sct",
"display": "Nitrilase",
"designation": [ {
"use": {
"code": "display",
"system": "http://terminology.hl7.org/CodeSystem/designation-usage"
},
"value": "Nitrilase (substance)",
"language": "en"
} ]
}, {
"code": "501001",
"system": "http://snomed.info/sct",
"display": "Blood group antibody Sf^a^",
"designation": [ {
"use": {
"code": "display",
"system": "http://terminology.hl7.org/CodeSystem/designation-usage"
},
"value": "Blood group antibody Stolzfus",
"language": "en"
}, {
"use": {
"code": "display",
"system": "http://terminology.hl7.org/CodeSystem/designation-usage"
},
"value": "Blood group antibody Sf^a^ (substance)",
"language": "en"
} ]
}, {
"code": "505005",
"system": "http://snomed.info/sct",
"display": "Blood group antibody M'",
"designation": [ {
"use": {
"code": "display",
"system": "http://terminology.hl7.org/CodeSystem/designation-usage"
},
"value": "Blood group antibody M' (substance)",
"language": "en"
} ]
}, {
"code": "506006",
"system": "http://snomed.info/sct",
"display": "3-oxosteroid delta^1^-dehydrogenase (substance)",
"designation": [ {
"use": {
"code": "display",
"system": "http://terminology.hl7.org/CodeSystem/designation-usage"
},
"value": "3-oxosteroid delta^1^-dehydrogenase",
"language": "en"
} ]
}, {
"code": "515004",
"system": "http://snomed.info/sct",
"display": "Blood group antigen Giaigue",
"designation": [ {
"use": {
"code": "display",
"system": "http://terminology.hl7.org/CodeSystem/designation-usage"
},
"value": "Blood group antigen Giaigue (substance)",
"language": "en"
} ]
}, {
"code": "519005",
"system": "http://snomed.info/sct",
"display": "Free protein S",
"designation": [ {
"use": {
"code": "display",
"system": "http://terminology.hl7.org/CodeSystem/designation-usage"
},
"value": "Free protein S (substance)",
"language": "en"
} ]
}, {
"code": "521000",
"system": "http://snomed.info/sct",
"display": "Mercury-197 (substance)",
"designation": [ {
"use": {
"code": "display",
"system": "http://terminology.hl7.org/CodeSystem/designation-usage"
},
"value": "Mercury-197",
"language": "en"
}, {
"use": {
"code": "display",
"system": "http://terminology.hl7.org/CodeSystem/designation-usage"
},
"value": "197-Hg",
"language": "en"
} ]
}, {
"code": "529003",
"system": "http://snomed.info/sct",
"display": "Guanosine",
"designation": [ {
"use": {
"code": "display",
"system": "http://terminology.hl7.org/CodeSystem/designation-usage"
},
"value": "Guanosine (substance)",
"language": "en"
} ]
}, {
"code": "538001",
"system": "http://snomed.info/sct",
"display": "2,3-dihydroxybenzoate 3,4-dioxygenase (substance)",
"designation": [ {
"use": {
"code": "display",
"system": "http://terminology.hl7.org/CodeSystem/designation-usage"
},
"value": "2,3-dihydroxybenzoate 3,4-dioxygenase",
"language": "en"
}, {
"use": {
"code": "display",
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} ]
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"value": "Hemoglobin Constant Spring",
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} ]
}, {
"code": "3672002",
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} ]
}, {
"code": "3684000",
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"display": "Phenylacetic acid",
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"value": "Phenylacetic acid (substance)",
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} ]
}, {
"code": "3689005",
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"value": "Hemoglobin Mizushi (substance)",
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} ]
}, {
"code": "3692009",
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"display": "Sodium sulfite",
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} ]
}, {
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} ]
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}, {
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},
"value": "Cytidine diphosphate (CDP) glycerol glycerophosphotransferase",
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}, {
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},
"value": "Cytidine diphosphate glycerol glycerophosphotransferase",
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}, {
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},
"value": "Cytidine diphosphate glycerol glycerophosphotransferase (substance)",
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} ]
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}, {
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}, {
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},
"value": "Prostaglandin synthase (substance)",
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} ]
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} ]
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}, {
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}, {
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"value": "Valine-transfer ribonucleic acid ligase",
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} ]
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"value": "Hemoglobin F-Port Royal (substance)",
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} ]
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} ]
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} ]
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}, {
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} ]
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"code": "8275006",
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} ]
}, {
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}, {
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}, {
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} ]
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} ]
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}, {
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}, {
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"value": "Revertase",
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}, {
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}, {
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} ]
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}, {
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} ]
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}, {
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"value": "Brilliant cresyl blue stain",
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} ]
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}, {
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} ]
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} ]
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} ]
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}, {
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}, {
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},
"value": "Cachectin",
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} ]
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}, {
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"value": "T-cell leukaemia-lymphoma gene 6",
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} ]
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} ]
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} ]
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} ]
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} ]
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