{
  "description": null,
  "_filename": "OperationDefinition-find-subject-variants.json",
  "package_name": "hl7.fhir.uv.genomics-reporting",
  "date": "2021-04-13T19:13:37+00:00",
  "system": false,
  "publisher": "HL7 International Clinical Genomics Work Group",
  "instance": false,
  "jurisdiction": [ {
    "coding": [ {
      "code": "001",
      "system": "http://unstats.un.org/unsd/methods/m49/m49.htm"
    } ]
  } ],
  "name": "FindSubjectVariants",
  "type": "true",
  "experimental": null,
  "resourceType": "OperationDefinition",
  "title": "Find Subject Variants",
  "package_version": "1.1.0",
  "status": "active",
  "id": "1ae8922d-c82c-4632-ae23-90b7d9a33860",
  "kind": "operation",
  "url": "http://hl7.org/fhir/uv/genomics-reporting/OperationDefinition/find-subject-variants",
  "code": "match",
  "version": "1.1.0",
  "contact": [ {
    "telecom": [ {
      "value": "http://www.hl7.org/Special/committees/clingenomics",
      "system": "url"
    } ]
  } ],
  "parameter": [ {
    "max": "1",
    "min": 1,
    "use": "in",
    "name": "subject",
    "type": "string",
    "searchType": "reference",
    "documentation": "The subject of interest."
  }, {
    "max": "1",
    "min": 1,
    "use": "in",
    "name": "region",
    "type": "Range",
    "documentation": "Region of interest is specified as a 0-based integer interval range. Variants that overlap the range are returned."
  }, {
    "max": "1",
    "min": 1,
    "use": "in",
    "name": "genomicRefSeq",
    "type": "string",
    "searchType": "token",
    "documentation": "Genomic reference sequence is a valid NCBI chromosome-level ('NC_') build 37 or build 38 identifier, or a valid mitochondrion identifier (NC_012920.1, NC_001807.4)"
  }, {
    "max": "*",
    "min": 0,
    "use": "out",
    "name": "regionStudied",
    "type": "canonical",
    "documentation": "[Profile: http://hl7.org/fhir/uv/genomics-reporting/StructureDefinition/region-studied] Must include 1..* component:ranges-examined; 1..1 component:coordinate-system (valued with '0-based interval counting'); 1..1 component:genomic-ref-seq.",
    "targetProfile": [ "http://hl7.org/fhir/uv/genomics-reporting/StructureDefinition/region-studied" ]
  }, {
    "max": "*",
    "min": 0,
    "use": "out",
    "name": "variant",
    "type": "canonical",
    "documentation": "[Profile: http://hl7.org/fhir/uv/genomics-reporting/StructureDefinition/variant] Must include valueCodeableConcept; component:genomic-source-class; component:genomic-ref-seq; component:allelic-state; component:ref-allele; component:alt-allele; component:coordinate-system (valued with '0-based interval counting'); component:exact-start-end.",
    "targetProfile": [ "http://hl7.org/fhir/uv/genomics-reporting/StructureDefinition/variant" ]
  }, {
    "max": "*",
    "min": 0,
    "use": "out",
    "name": "sequencePhaseRelationship",
    "type": "canonical",
    "documentation": "[Profile: http://hl7.org/fhir/uv/genomics-reporting/StructureDefinition/sequence-phase-relationship] Must include valueCodeableConcept; 2..2 derivedFrom:variant.",
    "targetProfile": [ "http://hl7.org/fhir/uv/genomics-reporting/StructureDefinition/sequence-phase-relationship" ]
  } ]
}