{
  "description": "Abbildung einer MII Bioprobe",
  "_filename": "ProfileSpecimenBioprobe.json",
  "package_name": "de.medizininformatikinitiative.kerndatensatz.biobank",
  "date": null,
  "derivation": "constraint",
  "publisher": null,
  "fhirVersion": "4.0.1",
  "name": "ProfileSpecimenBioprobe",
  "mapping": [ {
    "uri": "http://hl7.org/v3",
    "name": "RIM Mapping",
    "identity": "rim"
  }, {
    "uri": "http://hl7.org/fhir/fivews",
    "name": "FiveWs Pattern Mapping",
    "identity": "w5"
  }, {
    "uri": "http://hl7.org/v2",
    "name": "HL7 v2 Mapping",
    "identity": "v2"
  } ],
  "abstract": false,
  "type": "Specimen",
  "experimental": null,
  "resourceType": "StructureDefinition",
  "title": "Profile - Specimen- Bioprobe",
  "package_version": "0.9.0",
  "extension": [ {
    "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-category",
    "valueString": "Clinical.Diagnostics"
  }, {
    "url": "http://hl7.org/fhir/StructureDefinition/structuredefinition-security-category",
    "valueCode": "patient"
  } ],
  "status": "active",
  "id": "17de9696-c594-45b3-93ce-440301c179c4",
  "kind": "resource",
  "url": "https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Specimen",
  "version": null,
  "differential": {
    "element": [ {
      "id": "Specimen.extension",
      "min": 1,
      "path": "Specimen.extension",
      "slicing": {
        "rules": "open",
        "ordered": false,
        "discriminator": [ {
          "path": "url",
          "type": "value"
        } ]
      }
    }, {
      "id": "Specimen.extension:diagnose",
      "max": "1",
      "min": 0,
      "path": "Specimen.extension",
      "type": [ {
        "code": "Extension",
        "profile": [ "https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Diagnose" ]
      } ],
      "sliceName": "diagnose",
      "mustSupport": true
    }, {
      "id": "Specimen.extension:gehoertZu",
      "max": "1",
      "min": 1,
      "path": "Specimen.extension",
      "type": [ {
        "code": "Extension",
        "profile": [ "https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/VerwaltendeOrganisation" ]
      } ],
      "sliceName": "gehoertZu",
      "mustSupport": true
    }, {
      "id": "Specimen.identifier",
      "path": "Specimen.identifier",
      "mustSupport": true
    }, {
      "id": "Specimen.status",
      "min": 1,
      "path": "Specimen.status",
      "mustSupport": true
    }, {
      "id": "Specimen.type",
      "min": 1,
      "path": "Specimen.type",
      "mustSupport": true
    }, {
      "id": "Specimen.type.coding",
      "min": 1,
      "path": "Specimen.type.coding",
      "slicing": {
        "rules": "open",
        "discriminator": [ {
          "path": "system",
          "type": "pattern"
        } ]
      }
    }, {
      "id": "Specimen.type.coding:sct",
      "max": "*",
      "min": 1,
      "path": "Specimen.type.coding",
      "binding": {
        "strength": "extensible",
        "valueSet": "https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/ValueSet/probenart"
      },
      "sliceName": "sct"
    }, {
      "id": "Specimen.type.coding:sct.system",
      "min": 1,
      "path": "Specimen.type.coding.system",
      "patternUri": "http://snomed.info/sct"
    }, {
      "id": "Specimen.subject",
      "min": 1,
      "path": "Specimen.subject",
      "type": [ {
        "code": "Reference",
        "targetProfile": [ "http://hl7.org/fhir/StructureDefinition/Patient" ]
      } ]
    }, {
      "id": "Specimen.parent",
      "path": "Specimen.parent",
      "mustSupport": true
    }, {
      "id": "Specimen.collection",
      "min": 1,
      "path": "Specimen.collection"
    }, {
      "id": "Specimen.collection.extension",
      "path": "Specimen.collection.extension",
      "slicing": {
        "rules": "open",
        "ordered": false,
        "discriminator": [ {
          "path": "url",
          "type": "value"
        } ]
      }
    }, {
      "id": "Specimen.collection.extension:entnahmeprozedur",
      "max": "1",
      "min": 0,
      "path": "Specimen.collection.extension",
      "type": [ {
        "code": "Extension",
        "profile": [ "https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Entnahmeprozedur" ]
      } ],
      "sliceName": "entnahmeprozedur",
      "mustSupport": true
    }, {
      "id": "Specimen.collection.extension:einstellungBlutversorgung",
      "max": "1",
      "min": 0,
      "path": "Specimen.collection.extension",
      "type": [ {
        "code": "Extension",
        "profile": [ "https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/EinstellungBlutversorgung" ]
      } ],
      "sliceName": "einstellungBlutversorgung",
      "mustSupport": true
    }, {
      "id": "Specimen.collection.collected[x]",
      "min": 1,
      "path": "Specimen.collection.collected[x]",
      "mustSupport": true
    }, {
      "id": "Specimen.collection.bodySite",
      "path": "Specimen.collection.bodySite",
      "constraint": [ {
        "key": "mii-bb-1",
        "human": "Bei der Angabe der Entnahmestelle muss ein ICD-O-3 Topographiecode oder ein SNOMED CT Code angegeben werden.",
        "source": "https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Specimen",
        "severity": "error",
        "expression": "coding.where(system = 'http://snomed.info/sct' or system = 'http://terminology.hl7.org/CodeSystem/icd-o-3').exists()"
      } ],
      "mustSupport": true
    }, {
      "id": "Specimen.collection.bodySite.coding",
      "path": "Specimen.collection.bodySite.coding",
      "slicing": {
        "rules": "open",
        "discriminator": [ {
          "path": "system",
          "type": "pattern"
        } ]
      }
    }, {
      "id": "Specimen.collection.bodySite.coding:sct",
      "max": "1",
      "min": 0,
      "path": "Specimen.collection.bodySite.coding",
      "binding": {
        "strength": "required",
        "valueSet": "https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/ValueSet/sct-body-structures"
      },
      "sliceName": "sct",
      "mustSupport": true
    }, {
      "id": "Specimen.collection.bodySite.coding:sct.system",
      "min": 1,
      "path": "Specimen.collection.bodySite.coding.system",
      "patternUri": "http://snomed.info/sct"
    }, {
      "id": "Specimen.collection.bodySite.coding:icd-o-3",
      "max": "1",
      "min": 0,
      "path": "Specimen.collection.bodySite.coding",
      "binding": {
        "strength": "required",
        "valueSet": "https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/ValueSet/icd-o-3-topography"
      },
      "sliceName": "icd-o-3",
      "mustSupport": true
    }, {
      "id": "Specimen.collection.bodySite.coding:icd-o-3.system",
      "min": 1,
      "path": "Specimen.collection.bodySite.coding.system",
      "patternUri": "http://terminology.hl7.org/CodeSystem/icd-o-3"
    }, {
      "id": "Specimen.collection.fastingStatus[x]",
      "min": 1,
      "path": "Specimen.collection.fastingStatus[x]",
      "slicing": {
        "rules": "open",
        "ordered": false,
        "discriminator": [ {
          "path": "$this",
          "type": "type"
        } ]
      },
      "mustSupport": true
    }, {
      "id": "Specimen.collection.fastingStatusCodeableConcept",
      "max": "1",
      "min": 0,
      "path": "Specimen.collection.fastingStatusCodeableConcept",
      "type": [ {
        "code": "CodeableConcept"
      } ],
      "binding": {
        "strength": "required",
        "valueSet": "http://terminology.hl7.org/ValueSet/v2-0916"
      }
    }, {
      "id": "Specimen.processing",
      "path": "Specimen.processing",
      "slicing": {
        "rules": "open",
        "discriminator": [ {
          "path": "processing.procedure.coding",
          "type": "pattern"
        } ]
      }
    }, {
      "id": "Specimen.processing.extension",
      "min": 1,
      "path": "Specimen.processing.extension",
      "slicing": {
        "rules": "open",
        "ordered": false,
        "discriminator": [ {
          "path": "url",
          "type": "value"
        } ]
      }
    }, {
      "id": "Specimen.processing.extension:temperaturbedingungen",
      "max": "1",
      "min": 1,
      "path": "Specimen.processing.extension",
      "type": [ {
        "code": "Extension",
        "profile": [ "https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Temperaturbedingungen" ]
      } ],
      "sliceName": "temperaturbedingungen",
      "mustSupport": true
    }, {
      "id": "Specimen.processing.procedure",
      "min": 1,
      "path": "Specimen.processing.procedure",
      "binding": {
        "strength": "example",
        "valueSet": "https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/ValueSet/sct-specimen-preparation"
      },
      "constraint": [ {
        "key": "mii-bb-2",
        "human": "Wenn es sich nicht um einen Lagerprozess handelt, muss ein SCT Code angegeben werden.",
        "source": "https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Specimen",
        "severity": "error",
        "expression": "coding.where(system = 'http://snomed.info/sct' or code = 'LAGERUNG').exists()"
      } ],
      "mustSupport": true
    }, {
      "id": "Specimen.processing.procedure.coding",
      "path": "Specimen.processing.procedure.coding",
      "slicing": {
        "rules": "open",
        "discriminator": [ {
          "path": "system",
          "type": "pattern"
        } ]
      }
    }, {
      "id": "Specimen.processing.procedure.coding:sct",
      "max": "*",
      "min": 0,
      "path": "Specimen.processing.procedure.coding",
      "sliceName": "sct",
      "mustSupport": true,
      "patternCoding": {
        "system": "http://snomed.info/sct"
      }
    }, {
      "id": "Specimen.processing.additive",
      "path": "Specimen.processing.additive",
      "type": [ {
        "code": "Reference",
        "targetProfile": [ "https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Substance" ]
      } ],
      "mustSupport": true
    }, {
      "id": "Specimen.processing.time[x]",
      "min": 1,
      "path": "Specimen.processing.time[x]",
      "slicing": {
        "rules": "open",
        "ordered": false,
        "discriminator": [ {
          "path": "$this",
          "type": "type"
        } ]
      }
    }, {
      "id": "Specimen.processing.timePeriod",
      "max": "1",
      "min": 0,
      "path": "Specimen.processing.timePeriod",
      "type": [ {
        "code": "Period"
      } ],
      "mustSupport": true
    }, {
      "id": "Specimen.processing.timePeriod.start",
      "min": 1,
      "path": "Specimen.processing.timePeriod.start",
      "mustSupport": true
    }, {
      "id": "Specimen.processing.timePeriod.end",
      "path": "Specimen.processing.timePeriod.end",
      "mustSupport": true
    }, {
      "id": "Specimen.processing:lagerprozess",
      "max": "*",
      "min": 0,
      "path": "Specimen.processing",
      "sliceName": "lagerprozess",
      "mustSupport": true
    }, {
      "id": "Specimen.processing:lagerprozess.procedure.coding",
      "path": "Specimen.processing.procedure.coding",
      "patternCoding": {
        "code": "LAGERUNG",
        "system": "https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/CodeSystem/Probenlagerung",
        "display": "Lagerung einer Probe"
      }
    }, {
      "id": "Specimen.container.type",
      "min": 1,
      "path": "Specimen.container.type",
      "binding": {
        "strength": "extensible",
        "valueSet": "https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/ValueSet/containertyp"
      },
      "mustSupport": true
    }, {
      "id": "Specimen.container.capacity",
      "path": "Specimen.container.capacity",
      "mustSupport": true
    }, {
      "id": "Specimen.container.specimenQuantity",
      "path": "Specimen.container.specimenQuantity",
      "mustSupport": true
    }, {
      "id": "Specimen.container.additive[x]",
      "path": "Specimen.container.additive[x]",
      "type": [ {
        "code": "Reference",
        "targetProfile": [ "https://www.medizininformatik-initiative.de/fhir/ext/modul-biobank/StructureDefinition/Substance" ]
      } ],
      "mustSupport": true
    }, {
      "id": "Specimen.note",
      "path": "Specimen.note",
      "mustSupport": true
    } ]
  },
  "baseDefinition": "http://hl7.org/fhir/StructureDefinition/Specimen"
}