description: 'An HLA Antibody Assay Interpretation contains the overall human interpretation of an entire assay.\r\nThis includes which antigens/specificities are determined to be positive or negative.\r\n\r\nComponents of this observation:\r\n------------------------------------\r\ninterpretation-context: “Clinical Interpretation”\r\nreject-assay: Boolean if the assay was rejected or not.\r\nreject-reason: Reason for assay rejection\r\nfailure-code: Failure code generated for assay\r\npositive-specificities: multi-locus HLA GLstring of all loci and alleles considered positive\r\nquestionable-specificities: multi-locus HLA GLstring of all loci and alleles considered questionable\r\nnegative-specificities: multi-locus HLA GLstring of all loci and alleles considered negative'
package_name: hla.antibody.report
derivation: constraint
name: HLAImmunoassayInterpretation
type: Observation
elements:
  referenceRange: {index: 9}
  interpretation: {index: 5}
  encounter: {index: 2}
  specimen:
    mustSupport: true
    index: 7
    elements:
      reference: {index: 8}
    required: [reference]
  component:
    index: 10
    slicing:
      rules: open
      discriminator:
      - {path: $this, type: value}
      min: null
      slices:
        assay-rejected:
          match: {}
          schema:
            label: assay-rejected
            mustSupport: true
            index: 11
            elements:
              code:
                elements:
                  coding:
                    elements:
                      system:
                        binding: {strength: extensible, valueSet: 'http://fhir.nmdp.org/terminology/fhir/CodeSystem/hla-immunoassay-codes'}
                        mustSupport: true
                        index: 12
                      code:
                        binding: {strength: extensible, valueSet: 'http://fhir.nmdp.org/terminologyfhir/ValueSet//hla-immuno-assay-rejected-reason'}
                        mustSupport: true
                        index: 13
                    required: [code, system]
        assay-failure-code:
          match: {}
          schema:
            label: assay-failure-code
            mustSupport: true
            index: 14
            elements:
              code:
                elements:
                  coding:
                    elements:
                      system:
                        binding: {strength: extensible, valueSet: 'http://fhir.nmdp.org/terminology/fhir/CodeSystem/hla-immunoassay-codes'}
                        mustSupport: true
                        index: 15
                      code:
                        binding: {strength: extensible, valueSet: 'http://fhir.nmdp.org/terminology/fhir/ValueSet/hla-immuno-assay-failure-code'}
                        mustSupport: true
                        index: 16
                    required: [code, system]
        assay-interpretation-context:
          match: {}
          schema:
            label: assay-interpretation-context
            mustSupport: true
            _required: true
            index: 17
            elements:
              code:
                elements:
                  coding:
                    elements:
                      system: {mustSupport: false, index: 18}
                      code: {mustSupport: false, index: 19}
                  text:
                    pattern: {type: string, value: Clinical Interpretation}
                    mustSupport: true
                    type: string
                    index: 20
                required: [text]
        assay-interpretation-negative-specificities:
          match: {}
          schema:
            label: Negative Specificities
            mustSupport: true
            index: 21
            elements:
              code:
                elements:
                  coding:
                    elements:
                      system:
                        binding: {strength: required, valueSet: 'http://fhir.nmdp.org/terminology/fhir/CodeSystem/hla-immunoassay-codes'}
                        mustSupport: true
                        index: 22
                      code:
                        label: Specificity
                        binding: {strength: extensible, valueSet: 'http://fhir.nmdp.org/terminology/fhir/ValueSet/hla-immuno-assay-interpretation-specificity'}
                        pattern: {type: code, value: Negative}
                        mustSupport: true
                        type: code
                        index: 23
                    required: [code]
              value:
                label: Negative Specificities
                choices: [valueString]
                index: 25
              valueString: {type: string, label: Negative Specificities, choiceOf: value, index: 26}
            required: [value, valueString]
        assay-interpretation-positive-specificities:
          match: {}
          schema:
            index: 27
            elements:
              code:
                elements:
                  coding:
                    elements:
                      system:
                        binding: {strength: extensible, valueSet: 'http://fhir.nmdp.org/terminology/fhir/CodeSystem/hla-immunoassay-codes'}
                        mustSupport: true
                        index: 28
                      code:
                        label: Specificity
                        binding: {strength: extensible, valueSet: 'http://fhir.nmdp.org/terminology/fhir/ValueSet/hla-immunoassay-interpretation-specificity'}
                        pattern: {type: code, value: Positivie}
                        mustSupport: true
                        type: code
                        index: 29
                    required: [code, system]
              value:
                label: Positive Specificities
                mustSupport: true
                choices: [valueString]
                index: 31
              valueString: {type: string, label: Positive Specificities, mustSupport: true, choiceOf: value, index: 32}
            required: [value, valueString]
        assay-interpretation-questionable-specificities:
          match: {}
          schema:
            index: 33
            elements:
              code:
                elements:
                  coding:
                    elements:
                      system:
                        binding: {strength: extensible, valueSet: 'http://fhir.nmdp.org/terminology/fhir/CodeSystem/hla-immunoassay-codes'}
                        mustSupport: true
                        index: 34
                      version: {mustSupport: false, index: 35}
                      code:
                        label: Specificity
                        binding: {strength: extensible, valueSet: 'http://fhir.nmdp.org/terminology/fhir/ValueSet/hla-immunoassay-interpretation-specificity'}
                        pattern: {type: code, value: Questionable}
                        mustSupport: true
                        type: code
                        index: 36
                    required: [code, system]
              value:
                label: Questionable Specificities
                mustSupport: true
                choices: [valueString]
                index: 38
              valueString: {type: string, label: Questionable Specificities, mustSupport: true, choiceOf: value, index: 39}
  bodySite: {index: 6}
  focus: {index: 1}
  partOf:
    elements:
      reference: {label: HLA Antibody Diagnostic Report Ref, mustSupport: true, index: 0}
    required: [reference]
  performer:
    mustSupport: true
    index: 3
    elements:
      reference: {mustSupport: true, index: 4}
    required: [reference]
package_version: 0.1.2
class: profile
kind: resource
url: https://fhir.nmdp.org/ig/HlaAntibodyReport/StructureDefinition/hla-immuno-assay-interpretation
base: http://hl7.org/fhir/StructureDefinition/Observation
version: 0.0.1